Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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373 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD10 abhydrolase domain containing 10
ABHD17A abhydrolase domain containing 17A
ABRA actin binding Rho activating protein
ACYP2 acylphosphatase 2, muscle type
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ALOXE3 arachidonate lipoxygenase 3
ALX1 ALX homeobox 1
AMPD1 adenosine monophosphate deaminase 1
ANKRD30A ankyrin repeat domain 30A
APC2 adenomatosis polyposis coli 2
AQP11 aquaporin 11
ARHGAP5-AS1 ARHGAP5 antisense RNA 1 (head to head)
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASB3 ankyrin repeat and SOCS box containing 3
ATG4C autophagy related 4C, cysteine peptidase
ATP13A5 ATPase type 13A5
ATP9B ATPase, class II, type 9B
AVP arginine vasopressin
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6 B-cell CLL/lymphoma 6
BEX5 brain expressed, X-linked 5
C10ORF82 chromosome 10 open reading frame 82
C11ORF73 chromosome 11 open reading frame 73
C14ORF37 chromosome 14 open reading frame 37
C17ORF100 chromosome 17 open reading frame 100
C19ORF73 chromosome 19 open reading frame 73
C1QL1 complement component 1, q subcomponent-like 1
C1QL4 complement component 1, q subcomponent-like 4
C3ORF70 chromosome 3 open reading frame 70
C4ORF27 chromosome 4 open reading frame 27
C8ORF37 chromosome 8 open reading frame 37
C9ORF40 chromosome 9 open reading frame 40
CACHD1 cache domain containing 1
CADM4 cell adhesion molecule 4
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC85B coiled-coil domain containing 85B
CCDC85C coiled-coil domain containing 85C
CCKBR cholecystokinin B receptor
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CDKN2AIP CDKN2A interacting protein
CDX1 caudal type homeobox 1
CEPT1 choline/ethanolamine phosphotransferase 1
CES2 carboxylesterase 2
CETN4P centrin EF-hand protein 4, pseudogene
CFAP36 cilia and flagella associated protein 36
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli)
CIDEB cell death-inducing DFFA-like effector b
CKB creatine kinase, brain
CLP1 cleavage and polyadenylation factor I subunit 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNIH2 cornichon family AMPA receptor auxiliary protein 2
CNTFR ciliary neurotrophic factor receptor
CNTN4 contactin 4
COMMD1 copper metabolism (Murr1) domain containing 1
COPS4 COP9 signalosome subunit 4
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CRIPT cysteine-rich PDZ-binding protein
CST8 cystatin 8 (cystatin-related epididymal specific)
CTAG2 cancer/testis antigen 2
CXCL14 chemokine (C-X-C motif) ligand 14
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DACT2 dishevelled-binding antagonist of beta-catenin 2
DACT3 dishevelled-binding antagonist of beta-catenin 3
DBR1 debranching RNA lariats 1
DGAT2 diacylglycerol O-acyltransferase 2
DLX4 distal-less homeobox 4
DPF2 D4, zinc and double PHD fingers family 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNA2 ephrin-A2
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EHBP1 EH domain binding protein 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EMC10 ER membrane protein complex subunit 10
EMILIN3 elastin microfibril interfacer 3
EMX1 empty spiracles homeobox 1
ERC2-IT1 ERC2 intronic transcript 1
ERLEC1 endoplasmic reticulum lectin 1
ETFDH electron-transferring-flavoprotein dehydrogenase
EXOC3-AS1 EXOC3 antisense RNA 1
EXTL2 exostosin-like glycosyltransferase 2
FAM111B family with sequence similarity 111, member B
FAM120AOS family with sequence similarity 120A opposite strand
FAM161A family with sequence similarity 161, member A
FAM210B family with sequence similarity 210, member B
FAM218A family with sequence similarity 218, member A
FAM27L family with sequence similarity 27-like
FAM43A family with sequence similarity 43, member A
FAM57B family with sequence similarity 57, member B
FAM86B2 family with sequence similarity 86, member B2
FAM86DP family with sequence similarity 86, member D, pseudogene
FANCL Fanconi anemia, complementation group L
FBXO8 F-box protein 8
FGF10 fibroblast growth factor 10
FGF12 fibroblast growth factor 12
FIBP fibroblast growth factor (acidic) intracellular binding protein
FNTB farnesyltransferase, CAAX box, beta
FOXD2 forkhead box D2
FOXD3 forkhead box D3
FOXE3 forkhead box E3
FRMD6 FERM domain containing 6
FST follistatin
FYTTD1 forty-two-three domain containing 1
FZD3 frizzled class receptor 3
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GDF6 growth differentiation factor 6
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIP2 glutamate receptor interacting protein 2
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HAND2 heart and neural crest derivatives expressed 2
HAPLN4 hyaluronan and proteoglycan link protein 4
HCG4 HLA complex group 4 (non-protein coding)
HIST1H2AG histone cluster 1, H2ag
HIST1H2AL histone cluster 1, H2al
HIST1H2BB histone cluster 1, H2bb
HIST1H2BH histone cluster 1, H2bh
HIST1H2BL histone cluster 1, H2bl
HIST1H3C histone cluster 1, H3c
HIST1H3F histone cluster 1, H3f
HIST1H3J histone cluster 1, H3j
HMBOX1 homeobox containing 1
HMSD histocompatibility (minor) serpin domain containing
HOXD13 homeobox D13
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPSE heparanase
HRASLS HRAS-like suppressor
HSPA2 heat shock 70kDa protein 2
HTRA2 HtrA serine peptidase 2
HYAL3 hyaluronoglucosaminidase 3
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGSF1 immunoglobulin superfamily, member 1
ING2 inhibitor of growth family, member 2
INTS5 integrator complex subunit 5
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITM2C integral membrane protein 2C
JCHAIN joining chain of multimeric IgA and IgM
JPH3 junctophilin 3
KBTBD12 kelch repeat and BTB (POZ) domain containing 12
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1841 KIAA1841
KIRREL3 kin of IRRE like 3 (Drosophila)
KLF14 Kruppel-like factor 14
KLHL14 kelch-like family member 14
KLHL8 kelch-like family member 8
KPTN kaptin (actin binding protein)
KRT222 keratin 222, type II
KRT76 keratin 76, type II
KRTAP3-1 keratin associated protein 3-1
L2HGDH L-2-hydroxyglutarate dehydrogenase
LBX2 ladybird homeobox 2
LINC00092 long intergenic non-protein coding RNA 92
LINC00526 long intergenic non-protein coding RNA 526
LINGO3 leucine rich repeat and Ig domain containing 3
LKAAEAR1 LKAAEAR motif containing 1
LOC100132215 uncharacterized LOC100132215
LOC100272217 uncharacterized LOC100272217
LOC284578 uncharacterized LOC284578
LOC645166 lymphocyte-specific protein 1 pseudogene
LOC727924 uncharacterized LOC727924
LOC728613 programmed cell death 6 pseudogene
LPP LIM domain containing preferred translocation partner in lipoma
LRFN1 leucine rich repeat and fibronectin type III domain containing 1
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LRRC4B leucine rich repeat containing 4B
LRRIQ4 leucine-rich repeats and IQ motif containing 4
LUZP2 leucine zipper protein 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MB21D2 Mab-21 domain containing 2
MBLAC1 metallo-beta-lactamase domain containing 1
MC4R melanocortin 4 receptor
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MDH1 malate dehydrogenase 1, NAD (soluble)
MED19 mediator complex subunit 19
MEIS1 Meis homeobox 1
MEIS3 Meis homeobox 3
METTL7B methyltransferase like 7B
MFSD4 major facilitator superfamily domain containing 4
MGC2889 uncharacterized protein MGC2889
MOCS2 molybdenum cofactor synthesis 2
MON1A MON1 secretory trafficking family member A
MPPED1 metallophosphoesterase domain containing 1
MRPL16 mitochondrial ribosomal protein L16
MSH2 mutS homolog 2
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAF1 nuclear assembly factor 1 ribonucleoprotein
NAP1L3 nucleosome assembly protein 1-like 3
NAP1L5 nucleosome assembly protein 1-like 5
NDRG2 NDRG family member 2
NF1P1 neurofibromin 1 pseudogene 1
NFIA nuclear factor I/A
NKX2-4 NK2 homeobox 4
NKX2-6 NK2 homeobox 6
NME1-NME2 NME1-NME2 readthrough
NPR3 natriuretic peptide receptor 3
NPW neuropeptide W
NPY5R neuropeptide Y receptor Y5
NRL neural retina leucine zipper
NRXN1 neurexin 1
NRXN2 neurexin 2
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae)
NUBPL nucleotide binding protein-like
NXPH4 neurexophilin 4
OLFM2 olfactomedin 2
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OR14J1 olfactory receptor, family 14, subfamily J, member 1
OR4M2 olfactory receptor, family 4, subfamily M, member 2
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR4N3P olfactory receptor, family 4, subfamily N, member 3 pseudogene
OR4N4 olfactory receptor, family 4, subfamily N, member 4
OR4N5 olfactory receptor, family 4, subfamily N, member 5
OR5M10 olfactory receptor, family 5, subfamily M, member 10
OR7E5P olfactory receptor, family 7, subfamily E, member 5 pseudogene
OTX1 orthodenticle homeobox 1
OTX2 orthodenticle homeobox 2
PAIP2B poly(A) binding protein interacting protein 2B
PAPOLG poly(A) polymerase gamma
PARP8 poly (ADP-ribose) polymerase family, member 8
PCCB propionyl CoA carboxylase, beta polypeptide
PCDHA2 protocadherin alpha 2
PCDHA5 protocadherin alpha 5
PCDHA6 protocadherin alpha 6
PCDHB10 protocadherin beta 10
PCDHB13 protocadherin beta 13
PCDHB5 protocadherin beta 5
PCDHB7 protocadherin beta 7
PCDHB8 protocadherin beta 8
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDYN prodynorphin
PELI1 pellino E3 ubiquitin protein ligase 1
PELO pelota homolog (Drosophila)
PEX13 peroxisomal biogenesis factor 13
PIAS2 protein inhibitor of activated STAT, 2
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PRAC2 prostate cancer susceptibility candidate 2
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRORSD1P prolyl-tRNA synthetase associated domain containing 1, pseudogene
PRR35 proline rich 35
PRSS21 protease, serine, 21 (testisin)
PSME4 proteasome (prosome, macropain) activator subunit 4
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PURG purine-rich element binding protein G
PUS10 pseudouridylate synthase 10
RBM23 RNA binding motif protein 23
REG1A regenerating islet-derived 1 alpha
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REM2 RAS (RAD and GEM)-like GTP binding 2
RIT2 Ras-like without CAAX 2
RNASEH2C ribonuclease H2, subunit C
RPS2P32 ribosomal protein S2 pseudogene 32
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RTN4 reticulon 4
RWDD4 RWD domain containing 4
SDC2 syndecan 2
SDHAF2 succinate dehydrogenase complex assembly factor 2
SELV selenoprotein V
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHISA7 shisa family member 7
SIAH3 siah E3 ubiquitin protein ligase family member 3
SIRT4 sirtuin 4
SLAMF9 SLAM family member 9
SLC22A20 solute carrier family 22, member 20
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SMAD5-AS1 SMAD5 antisense RNA 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNORA15 small nucleolar RNA, H/ACA box 15
SOCS1 suppressor of cytokine signaling 1
SOCS5 suppressor of cytokine signaling 5
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1
SORCS3 sortilin-related VPS10 domain containing receptor 3
SOX21 SRY (sex determining region Y)-box 21
SPATA31C1 SPATA31 subfamily C, member 1
SRBD1 S1 RNA binding domain 1
SSTR5 somatostatin receptor 5
STX5 syntaxin 5
STXBP6 syntaxin binding protein 6 (amisyn)
SUGT1P1 SUGT1 pseudogene 1
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYT16 synaptotagmin XVI
SYT3 synaptotagmin III
TBCCD1 TBCC domain containing 1
TCEAL5 transcription elongation factor A (SII)-like 5
TCTE3 t-complex-associated-testis-expressed 3
TEAD2 TEA domain family member 2
TFF2 trefoil factor 2
TGFB2 transforming growth factor, beta 2
TGM3 transglutaminase 3
TGM7 transglutaminase 7
THAP11 THAP domain containing 11
THAP9 THAP domain containing 9
THBS4 thrombospondin 4
THSD7B thrombospondin, type I, domain containing 7B
THTPA thiamine triphosphatase
TM7SF2 transmembrane 7 superfamily member 2
TMEM109 transmembrane protein 109
TMEM121 transmembrane protein 121
TMEM126A transmembrane protein 126A
TMEM135 transmembrane protein 135
TMEM17 transmembrane protein 17
TMEM179B transmembrane protein 179B
TMEM216 transmembrane protein 216
TMX2 thioredoxin-related transmembrane protein 2
TPGS1 tubulin polyglutamylase complex subunit 1
TRIM32 tripartite motif containing 32
TRIM49 tripartite motif containing 49
TRIM53AP tripartite motif containing 53A, pseudogene
TSPYL4 TSPY-like 4
TST thiosulfate sulfurtransferase (rhodanese)
TTC33 tetratricopeptide repeat domain 33
TTC9C tetratricopeptide repeat domain 9C
TTYH1 tweety family member 1
TUBA3D tubulin, alpha 3d
TUBA3E tubulin, alpha 3e
TYMSOS TYMS opposite strand
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UFSP2 UFM1-specific peptidase 2
UGP2 UDP-glucose pyrophosphorylase 2
USP1 ubiquitin specific peptidase 1
VWCE von Willebrand factor C and EGF domains
WDPCP WD repeat containing planar cell polarity effector
WIF1 WNT inhibitory factor 1
WNK4 WNK lysine deficient protein kinase 4
WSCD2 WSC domain containing 2
XPO1 exportin 1
XXYLT1 xyloside xylosyltransferase 1
YPEL4 yippee-like 4 (Drosophila)
ZADH2 zinc binding alcohol dehydrogenase domain containing 2
ZBTB42 zinc finger and BTB domain containing 42
ZFP37 ZFP37 zinc finger protein
ZNF114 zinc finger protein 114
ZNF131 zinc finger protein 131
ZNF134 zinc finger protein 134
ZNF180 zinc finger protein 180
ZNF219 zinc finger protein 219
ZNF233 zinc finger protein 233
ZNF271P zinc finger protein 271, pseudogene
ZNF416 zinc finger protein 416
ZNF542P zinc finger protein 542, pseudogene
ZNF575 zinc finger protein 575
ZNF582 zinc finger protein 582
ZNF583 zinc finger protein 583
ZNF584 zinc finger protein 584
ZNF613 zinc finger protein 613
ZNF615 zinc finger protein 615
ZNF658 zinc finger protein 658
ZNF883 zinc finger protein 883
ZSCAN1 zinc finger and SCAN domain containing 1

low expression

Symbol Name
ZNF777 zinc finger protein 777