Lung squamous cell carcinoma_LUSC_TCGA-43-A474-01A-11R-A24H-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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313 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-43-A474-01A-11R-A24H-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ACTL10 actin-like 10
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALOX12 arachidonate 12-lipoxygenase
AMN amnion associated transmembrane protein
ANKMY2 ankyrin repeat and MYND domain containing 2
ANKRD9 ankyrin repeat domain 9
AOX1 aldehyde oxidase 1
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
ASIC5 acid sensing (proton gated) ion channel family member 5
ATF4 activating transcription factor 4
ATN1 atrophin 1
ATP13A5 ATPase type 13A5
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
BCL6 B-cell CLL/lymphoma 6
BRAT1 BRCA1-associated ATM activator 1
BTG3 BTG family, member 3
C10ORF91 chromosome 10 open reading frame 91
C12ORF75 chromosome 12 open reading frame 75
C14ORF169 chromosome 14 open reading frame 169
C16ORF90 chromosome 16 open reading frame 90
C1ORF100 chromosome 1 open reading frame 100
C20ORF144 chromosome 20 open reading frame 144
C20ORF197 chromosome 20 open reading frame 197
C3ORF67 chromosome 3 open reading frame 67
CALB1 calbindin 1, 28kDa
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CBWD3 COBW domain containing 3
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC169 coiled-coil domain containing 169
CCDC185 coiled-coil domain containing 185
CCDC3 coiled-coil domain containing 3
CCDC34 coiled-coil domain containing 34
CCSER1 coiled-coil serine-rich protein 1
CCT6P1 chaperonin containing TCP1, subunit 6 (zeta) pseudogene 1
CD44 CD44 molecule (Indian blood group)
CENPE centromere protein E, 312kDa
CEP162 centrosomal protein 162kDa
CEP72 centrosomal protein 72kDa
CERK ceramide kinase
CERS6 ceramide synthase 6
CKB creatine kinase, brain
CLEC18A C-type lectin domain family 18, member A
CLEC18B C-type lectin domain family 18, member B
CLUAP1 clusterin associated protein 1
COL7A1 collagen, type VII, alpha 1
CORO6 coronin 6
COX19 COX19 cytochrome c oxidase assembly factor
CREB5 cAMP responsive element binding protein 5
CRYAA crystallin, alpha A
CTSV cathepsin V
CYCS cytochrome c, somatic
CYCSP52 cytochrome c, somatic pseudogene 52
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCC DCC netrin 1 receptor
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DENND5A DENN/MADD domain containing 5A
DLD dihydrolipoamide dehydrogenase
DNAH11 dynein, axonemal, heavy chain 11
DNM1L dynamin 1-like
DPF1 D4, zinc and double PHD fingers family 1
DPY19L2P2 DPY19L2 pseudogene 2
DTD1 D-tyrosyl-tRNA deacylase 1
EFCAB3 EF-hand calcium binding domain 3
EHBP1 EH domain binding protein 1
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EMC2 ER membrane protein complex subunit 2
ESR2 estrogen receptor 2 (ER beta)
EYA1 EYA transcriptional coactivator and phosphatase 1
FAM122A family with sequence similarity 122A
FAM132A family with sequence similarity 132, member A
FAM210A family with sequence similarity 210, member A
FBN2 fibrillin 2
FGF21 fibroblast growth factor 21
FGFBP2 fibroblast growth factor binding protein 2
FKBP4 FK506 binding protein 4, 59kDa
FKBP6 FK506 binding protein 6, 36kDa
FLJ13224 uncharacterized LOC79857
FLJ42627 uncharacterized LOC645644
FOXP2 forkhead box P2
FSCN1 fascin actin-bundling protein 1
FST follistatin
FXN frataxin
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18
GARS glycyl-tRNA synthetase
GCSH glycine cleavage system protein H (aminomethyl carrier)
GDI1 GDP dissociation inhibitor 1
GLI1 GLI family zinc finger 1
GLI4 GLI family zinc finger 4
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GSTA3 glutathione S-transferase alpha 3
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTM3 glutathione S-transferase mu 3 (brain)
GTF2I general transcription factor IIi
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GTPBP10 GTP-binding protein 10 (putative)
HAGHL hydroxyacylglutathione hydrolase-like
HHAT hedgehog acyltransferase
HHIPL2 HHIP-like 2
HIBADH 3-hydroxyisobutyrate dehydrogenase
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene
HIP1 huntingtin interacting protein 1
HIST1H1E histone cluster 1, H1e
HKDC1 hexokinase domain containing 1
HOXA11-AS HOXA11 antisense RNA
HOXD10 homeobox D10
HOXD11 homeobox D11
HR hair growth associated
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB3 heat shock 27kDa protein 3
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HYAL3 hyaluronoglucosaminidase 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INF2 inverted formin, FH2 and WH2 domain containing
IPO7 importin 7
IRF2BP2 interferon regulatory factor 2 binding protein 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB8 integrin, beta 8
IZUMO2 IZUMO family member 2
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KCTD16 potassium channel tetramerization domain containing 16
KIAA1671 KIAA1671
KLC1 kinesin light chain 1
KLF5 Kruppel-like factor 5 (intestinal)
KRT17 keratin 17, type I
LAMA1 laminin, alpha 1
LDHA lactate dehydrogenase A
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LHX5 LIM homeobox 5
LOC541473 FK506 binding protein 6, 36kDa pseudogene
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1
LRP1B low density lipoprotein receptor-related protein 1B
LRP4 low density lipoprotein receptor-related protein 4
LTBP4 latent transforming growth factor beta binding protein 4
MAN1A2 mannosidase, alpha, class 1A, member 2
MAP2 microtubule-associated protein 2
MAPK12 mitogen-activated protein kinase 12
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MEIS3 Meis homeobox 3
METTL15 methyltransferase like 15
MFSD4 major facilitator superfamily domain containing 4
MIOX myo-inositol oxygenase
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPLKIP M-phase specific PLK1 interacting protein
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MTA1 metastasis associated 1
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO16 myosin XVI
MYO3A myosin IIIA
MYOM3 myomesin 3
NAMPT nicotinamide phosphoribosyltransferase
NDRG1 N-myc downstream regulated 1
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NECAB2 N-terminal EF-hand calcium binding protein 2
NEK7 NIMA-related kinase 7
NELL2 NEL-like 2 (chicken)
NFE2L2 nuclear factor, erythroid 2-like 2
NGB neuroglobin
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NKD2 naked cuticle homolog 2 (Drosophila)
NOBOX NOBOX oogenesis homeobox
NR5A1 nuclear receptor subfamily 5, group A, member 1
NT5DC2 5'-nucleotidase domain containing 2
ODC1 ornithine decarboxylase 1
ONECUT1 one cut homeobox 1
OR1F1 olfactory receptor, family 1, subfamily F, member 1
OR51I2 olfactory receptor, family 51, subfamily I, member 2
OSBPL6 oxysterol binding protein-like 6
OTOP2 otopetrin 2
OTOP3 otopetrin 3
P3H2 prolyl 3-hydroxylase 2
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PCDHB10 protocadherin beta 10
PCDHB2 protocadherin beta 2
PCDHGA10 protocadherin gamma subfamily A, 10
PCLO piccolo presynaptic cytomatrix protein
PCSK5 proprotein convertase subtilisin/kexin type 5
PELO pelota homolog (Drosophila)
PFKM phosphofructokinase, muscle
PFKP phosphofructokinase, platelet
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PKP1 plakophilin 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2R1 phospholipase A2 receptor 1, 180kDa
PMS2CL PMS2 C-terminal like pseudogene
POR P450 (cytochrome) oxidoreductase
POU6F2 POU class 6 homeobox 2
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRMT3 protein arginine methyltransferase 3
PSPN persephin
PTHLH parathyroid hormone-like hormone
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRK protein tyrosine phosphatase, receptor type, K
PYDC2 pyrin domain containing 2
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2
RAP1GAP2 RAP1 GTPase activating protein 2
RCOR1 REST corepressor 1
RIPPLY2 ripply transcriptional repressor 2
RNF175 ring finger protein 175
RNFT2 ring finger protein, transmembrane 2
RPS2P32 ribosomal protein S2 pseudogene 32
RUNX1-IT1 RUNX1 intronic transcript 1
SAAL1 serum amyloid A-like 1
SBF2 SET binding factor 2
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCRN1 secernin 1
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SERHL serine hydrolase-like (pseudogene)
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SLC35F3 solute carrier family 35, member F3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC45A4 solute carrier family 45, member 4
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMC5 structural maintenance of chromosomes 5
SMYD3 SET and MYND domain containing 3
SNAI2 snail family zinc finger 2
SNORA71B small nucleolar RNA, H/ACA box 71B
SNW1 SNW domain containing 1
SNX5 sorting nexin 5
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SOSTDC1 sclerostin domain containing 1
SPATA21 spermatogenesis associated 21
SPIRE2 spire-type actin nucleation factor 2
SREBF1 sterol regulatory element binding transcription factor 1
SRPX sushi-repeat containing protein, X-linked
SSTR5 somatostatin receptor 5
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYNM synemin, intermediate filament protein
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D4 TBC1 domain family, member 4
TBX18 T-box 18
TCHH trichohyalin
TDH L-threonine dehydrogenase (pseudogene)
TEX15 testis expressed 15
TIAM2 T-cell lymphoma invasion and metastasis 2
TKT transketolase
TMEM81 transmembrane protein 81
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNRC18 trinucleotide repeat containing 18
TPPP tubulin polymerization promoting protein
TRIM45 tripartite motif containing 45
TRIM7 tripartite motif containing 7
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSG101 tumor susceptibility 101
TSPAN18 tetraspanin 18
TSPAN7 tetraspanin 7
TSPAN9 tetraspanin 9
TTC21B tetratricopeptide repeat domain 21B
TTF2 transcription termination factor, RNA polymerase II
TTLL12 tubulin tyrosine ligase-like family member 12
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UGDH UDP-glucose 6-dehydrogenase
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
USH1G Usher syndrome 1G (autosomal recessive)
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR3 WD repeat domain 3
WDYHV1 WDYHV motif containing 1
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
YBX3 Y box binding protein 3
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZDHHC11 zinc finger, DHHC-type containing 11
ZFAT zinc finger and AT hook domain containing
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF276 zinc finger protein 276
ZNF556 zinc finger protein 556

low expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALG9 ALG9, alpha-1,2-mannosyltransferase
BUD13 BUD13 homolog (S. cerevisiae)
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EXOC2 exocyst complex component 2
HINFP histone H4 transcription factor
PICALM phosphatidylinositol binding clathrin assembly protein
UBE4A ubiquitination factor E4A