Lung squamous cell carcinoma_LUSC_TCGA-66-2773-01A-01R-1201-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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258 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-66-2773-01A-01R-1201-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABLIM1 actin binding LIM protein 1
ACKR3 atypical chemokine receptor 3
ADAM17 ADAM metallopeptidase domain 17
ADAM28 ADAM metallopeptidase domain 28
ADHFE1 alcohol dehydrogenase, iron containing, 1
ADSS adenylosuccinate synthase
AGFG1 ArfGAP with FG repeats 1
AHCYL1 adenosylhomocysteinase-like 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANO7 anoctamin 7
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
AP3B2 adaptor-related protein complex 3, beta 2 subunit
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
ASPH aspartate beta-hydroxylase
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATRN attractin
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCL2L1 BCL2-like 1
BMPR1B bone morphogenetic protein receptor, type IB
BTBD2 BTB (POZ) domain containing 2
C12ORF4 chromosome 12 open reading frame 4
C16ORF52 chromosome 16 open reading frame 52
C1ORF177 chromosome 1 open reading frame 177
C2CD2 C2 calcium-dependent domain containing 2
C2CD4A C2 calcium-dependent domain containing 4A
C8ORF74 chromosome 8 open reading frame 74
CALB2 calbindin 2
CAPN13 calpain 13
CASC4 cancer susceptibility candidate 4
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CCDC129 coiled-coil domain containing 129
CCDC160 coiled-coil domain containing 160
CCNYL1 cyclin Y-like 1
CCPG1 cell cycle progression 1
CCR3 chemokine (C-C motif) receptor 3
CD276 CD276 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDCA2 cell division cycle associated 2
CDH26 cadherin 26
CDYL chromodomain protein, Y-like
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CES1P1 carboxylesterase 1 pseudogene 1
CHMP7 charged multivesicular body protein 7
CHP2 calcineurin-like EF-hand protein 2
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CIB3 calcium and integrin binding family member 3
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
CMTM8 CKLF-like MARVEL transmembrane domain containing 8
CMTR2 cap methyltransferase 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNOT7 CCR4-NOT transcription complex, subunit 7
COLCA1 colorectal cancer associated 1
CP ceruloplasmin (ferroxidase)
CPD carboxypeptidase D
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPNE4 copine IV
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTSB cathepsin B
CTSC cathepsin C
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP4F29P cytochrome P450, family 4, subfamily F, polypeptide 29, pseudogene
DEFB1 defensin, beta 1
DENND4A DENN/MADD domain containing 4A
DGCR10 DiGeorge syndrome critical region gene 10 (non-protein coding)
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DKFZP434K028 uncharacterized LOC26070
DMTN dematin actin binding protein
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DOCK5 dedicator of cytokinesis 5
DTX3L deltex 3 like, E3 ubiquitin ligase
EEA1 early endosome antigen 1
EGF epidermal growth factor
ELP3 elongator acetyltransferase complex subunit 3
EPGN epithelial mitogen
EPHB3 EPH receptor B3
EPS8 epidermal growth factor receptor pathway substrate 8
ERC2 ELKS/RAB6-interacting/CAST family member 2
ERI1 exoribonuclease 1
ERMP1 endoplasmic reticulum metallopeptidase 1
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ESR1 estrogen receptor 1
F5 coagulation factor V (proaccelerin, labile factor)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM138D family with sequence similarity 138, member D
FAM13A-AS1 FAM13A antisense RNA 1
FAM153B family with sequence similarity 153, member B
FOXL2NB FOXL2 neighbor
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
G6PD glucose-6-phosphate dehydrogenase
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GAL3ST2 galactose-3-O-sulfotransferase 2
GCLC glutamate-cysteine ligase, catalytic subunit
GPR45 G protein-coupled receptor 45
GSR glutathione reductase
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HHIPL2 HHIP-like 2
HKDC1 hexokinase domain containing 1
HM13 histocompatibility (minor) 13
HMBOX1 homeobox containing 1
HPN hepsin
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
IL37 interleukin 37
IL7 interleukin 7
INTS9 integrator complex subunit 9
KIAA0319 KIAA0319
KYNU kynureninase
LINC00521 long intergenic non-protein coding RNA 521
LOC100272216 uncharacterized LOC100272216
LOC285692 uncharacterized LOC285692
LOC641367 cyclin Y-like 1 pseudogene
LRG1 leucine-rich alpha-2-glycoprotein 1
MAPK11 mitogen-activated protein kinase 11
MCPH1 microcephalin 1
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGST1 microsomal glutathione S-transferase 1
MOB3C MOB kinase activator 3C
MPZL2 myelin protein zero-like 2
MTMR9 myotubularin related protein 9
MTUS1 microtubule associated tumor suppressor 1
NAMPT nicotinamide phosphoribosyltransferase
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NEU4 sialidase 4
NKX1-2 NK1 homeobox 2
NMB neuromedin B
NOXRED1 NADP-dependent oxidoreductase domain containing 1
NRG1 neuregulin 1
NRG4 neuregulin 4
OPRK1 opioid receptor, kappa 1
OR5B12 olfactory receptor, family 5, subfamily B, member 12
PANX2 pannexin 2
PDE7A phosphodiesterase 7A
PDRG1 p53 and DNA-damage regulated 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLIN4 perilipin 4
PLIN5 perilipin 5
PLS1 plastin 1
PNPO pyridoxamine 5'-phosphate oxidase
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POM121L10P POM121 transmembrane nucleoporin-like 10, pseudogene
POM121L8P POM121 transmembrane nucleoporin-like 8 pseudogene
PPAP2C phosphatidic acid phosphatase type 2C
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRINS psoriasis associated non-protein coding RNA induced by stress
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRSS1 protease, serine, 1 (trypsin 1)
PRSS3P2 protease, serine, 3 pseudogene 2
PTPRS protein tyrosine phosphatase, receptor type, S
R3HCC1 R3H domain and coiled-coil containing 1
RAB10 RAB10, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RBM4B RNA binding motif protein 4B
RDH10 retinol dehydrogenase 10 (all-trans)
RESP18 regulated endocrine-specific protein 18
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RFPL1S RFPL1 antisense RNA 1
RFPL3 ret finger protein-like 3
RNASE3 ribonuclease, RNase A family, 3
RNF111 ring finger protein 111
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF24 ring finger protein 24
ROM1 retinal outer segment membrane protein 1
RPE ribulose-5-phosphate-3-epimerase
SBNO2 strawberry notch homolog 2 (Drosophila)
SDSL serine dehydratase-like
SELL selectin L
SEPT12 septin 12
SGMS1 sphingomyelin synthase 1
SH2D4A SH2 domain containing 4A
SH2D6 SH2 domain containing 6
SHISA9 shisa family member 9
SHROOM1 shroom family member 1
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC23A3 solute carrier family 23, member 3
SLC26A8 solute carrier family 26 (anion exchanger), member 8
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA70 small nucleolar RNA, H/ACA box 70
SOST sclerostin
SPP1 secreted phosphoprotein 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STC2 stanniocalcin 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYT2 synaptotagmin II
TAS2R50 taste receptor, type 2, member 50
TBC1D29 TBC1 domain family, member 29
TBC1D3C TBC1 domain family, member 3C
TBC1D3P1-DHX40P1 TBC1D3P1-DHX40P1 readthrough transcribed pseudogene
TDP2 tyrosyl-DNA phosphodiesterase 2
TDRD6 tudor domain containing 6
TFG TRK-fused gene
TJP3 tight junction protein 3
TLE6 transducin-like enhancer of split 6
TLK1 tousled-like kinase 1
TMEM184A transmembrane protein 184A
TMEM213 transmembrane protein 213
TMPRSS4 transmembrane protease, serine 4
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNPO1 transportin 1
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TP53I3 tumor protein p53 inducible protein 3
TPST2 tyrosylprotein sulfotransferase 2
TPX2 TPX2, microtubule-associated
TREML3P triggering receptor expressed on myeloid cells-like 3, pseudogene
TREML4 triggering receptor expressed on myeloid cells-like 4
TREML5P triggering receptor expressed on myeloid cells-like 5, pseudogene
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSKU tsukushi, small leucine rich proteoglycan
TTC22 tetratricopeptide repeat domain 22
TTI2 TELO2 interacting protein 2
TUBA8 tubulin, alpha 8
TUSC3 tumor suppressor candidate 3
TXNRD1 thioredoxin reductase 1
UBFD1 ubiquitin family domain containing 1
UBXN8 UBX domain protein 8
USP28 ubiquitin specific peptidase 28
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VWA7 von Willebrand factor A domain containing 7
WDR18 WD repeat domain 18
WNT11 wingless-type MMTV integration site family, member 11
WNT5A wingless-type MMTV integration site family, member 5A
XPO7 exportin 7
ZDHHC2 zinc finger, DHHC-type containing 2
ZDHHC9 zinc finger, DHHC-type containing 9
ZFAND6 zinc finger, AN1-type domain 6
ZNF148 zinc finger protein 148
ZNF488 zinc finger protein 488

low expression

Symbol Name
LRIF1 ligand dependent nuclear receptor interacting factor 1