Lung squamous cell carcinoma_LUSC_TCGA-85-8288-01A-11R-2296-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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378 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-85-8288-01A-11R-2296-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACAN aggrecan
ACBD7 acyl-CoA binding domain containing 7
ADAM22 ADAM metallopeptidase domain 22
ADAM8 ADAM metallopeptidase domain 8
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
AEBP1 AE binding protein 1
AGO1 argonaute RISC catalytic component 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKAP3 A kinase (PRKA) anchor protein 3
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALPK1 alpha-kinase 1
ALPK2 alpha-kinase 2
AMOTL1 angiomotin like 1
ANGPT2 angiopoietin 2
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD11 ankyrin repeat domain 11
ANKRD30BL ankyrin repeat domain 30B-like
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
ANTXR1 anthrax toxin receptor 1
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ARL17B ADP-ribosylation factor-like 17B
ARL3 ADP-ribosylation factor-like 3
ARL9 ADP-ribosylation factor-like 9
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASB13 ankyrin repeat and SOCS box containing 13
ATF5 activating transcription factor 5
ATXN2L ataxin 2-like
ATXN7L2 ataxin 7-like 2
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
BCHE butyrylcholinesterase
BLNK B-cell linker
BTN2A2 butyrophilin, subfamily 2, member A2
C10ORF12 chromosome 10 open reading frame 12
C10ORF2 chromosome 10 open reading frame 2
C12ORF65 chromosome 12 open reading frame 65
C21ORF2 chromosome 21 open reading frame 2
C4ORF46 chromosome 4 open reading frame 46
C6ORF222 chromosome 6 open reading frame 222
C7ORF33 chromosome 7 open reading frame 33
CACTIN cactin, spliceosome C complex subunit
CALD1 caldesmon 1
CALR calreticulin
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CBX5 chromobox homolog 5
CCAR2 cell cycle and apoptosis regulator 2
CCDC102A coiled-coil domain containing 102A
CCDC146 coiled-coil domain containing 146
CCDC158 coiled-coil domain containing 158
CCDC25 coiled-coil domain containing 25
CCDC28B coiled-coil domain containing 28B
CCNF cyclin F
CCNI2 cyclin I family, member 2
CCNJ cyclin J
CD207 CD207 molecule, langerin
CD320 CD320 molecule
CDH23 cadherin-related 23
CDIP1 cell death-inducing p53 target 1
CDK18 cyclin-dependent kinase 18
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20
CEACAM22P carcinoembryonic antigen-related cell adhesion molecule 22, pseudogene
CEP83 centrosomal protein 83kDa
CFAP97 cilia and flagella associated protein 97
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHMP7 charged multivesicular body protein 7
CHODL-AS1 CHODL antisense RNA 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CIT citron rho-interacting serine/threonine kinase
CLCN4 chloride channel, voltage-sensitive 4
CLCN7 chloride channel, voltage-sensitive 7
CLDN14 claudin 14
CLDN16 claudin 16
CLEC18A C-type lectin domain family 18, member A
CLEC18C C-type lectin domain family 18, member C
CNN3 calponin 3, acidic
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL12A1 collagen, type XII, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL22A1 collagen, type XXII, alpha 1
COL23A1 collagen, type XXIII, alpha 1
COL8A1 collagen, type VIII, alpha 1
COL8A2 collagen, type VIII, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COMP cartilage oligomeric matrix protein
CORIN corin, serine peptidase
CR1L complement component (3b/4b) receptor 1-like
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CSNK1G2 casein kinase 1, gamma 2
CTGF connective tissue growth factor
CTIF CBP80/20-dependent translation initiation factor
CUEDC2 CUE domain containing 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDA1 DET1 and DDB1 associated 1
DGAT2 diacylglycerol O-acyltransferase 2
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DNAH6 dynein, axonemal, heavy chain 6
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
DOHH deoxyhypusine hydroxylase/monooxygenase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
E2F2 E2F transcription factor 2
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
EBF3 early B-cell factor 3
ECE1 endothelin converting enzyme 1
EDC4 enhancer of mRNA decapping 4
EFCAB5 EF-hand calcium binding domain 5
EMID1 EMI domain containing 1
EN2 engrailed homeobox 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6
EP400 E1A binding protein p400
ERI1 exoribonuclease 1
ESR1 estrogen receptor 1
EWSAT1 Ewing sarcoma associated transcript 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FABP6 fatty acid binding protein 6, ileal
FAM117A family with sequence similarity 117, member A
FAM171A1 family with sequence similarity 171, member A1
FAM180A family with sequence similarity 180, member A
FAM196B family with sequence similarity 196, member B
FAM208B family with sequence similarity 208, member B
FAM24A family with sequence similarity 24, member A
FAM53B family with sequence similarity 53, member B
FAM65C family with sequence similarity 65, member C
FAS Fas cell surface death receptor
FBLN2 fibulin 2
FBXO31 F-box protein 31
FBXW8 F-box and WD repeat domain containing 8
FCGBP Fc fragment of IgG binding protein
FGF1 fibroblast growth factor 1 (acidic)
FGF16 fibroblast growth factor 16
FGF18 fibroblast growth factor 18
FGF22 fibroblast growth factor 22
FHOD3 formin homology 2 domain containing 3
FMOD fibromodulin
FNDC1 fibronectin type III domain containing 1
FOXN1 forkhead box N1
FOXQ1 forkhead box Q1
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GANAB glucosidase, alpha; neutral AB
GAS6 growth arrest-specific 6
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLB1L2 galactosidase, beta 1-like 2
GLIS2 GLIS family zinc finger 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GOLGA8DP golgin A8 family, member D, pseudogene
GOLGA8EP golgin A8 family, member E, pseudogene
GOLGA8F golgin A8 family, member F
GOLGA8G golgin A8 family, member G
GPR137 G protein-coupled receptor 137
GPR156 G protein-coupled receptor 156
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAPLN1 hyaluronan and proteoglycan link protein 1
HAPLN3 hyaluronan and proteoglycan link protein 3
HCG4B HLA complex group 4B (non-protein coding)
HCRTR1 hypocretin (orexin) receptor 1
HECA headcase homolog (Drosophila)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMGN5 high mobility group nucleosome binding domain 5
HOXA11-AS HOXA11 antisense RNA
HSDL1 hydroxysteroid dehydrogenase like 1
HSPG2 heparan sulfate proteoglycan 2
HYLS1 hydrolethalus syndrome 1
HYOU1 hypoxia up-regulated 1
ICOSLG inducible T-cell co-stimulator ligand
IGSF3 immunoglobulin superfamily, member 3
IL23A interleukin 23, alpha subunit p19
IL27RA interleukin 27 receptor, alpha
INGX inhibitor of growth family, X-linked, pseudogene
INTS9 integrator complex subunit 9
IPMK inositol polyphosphate multikinase
ISM1 isthmin 1, angiogenesis inhibitor
ITGA11 integrin, alpha 11
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JAK3 Janus kinase 3
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDM2B lysine (K)-specific demethylase 2B
KIAA1024 KIAA1024
KIAA1217 KIAA1217
KIF3C kinesin family member 3C
KIRREL2 kin of IRRE like 2 (Drosophila)
KLF1 Kruppel-like factor 1 (erythroid)
KRTAP10-2 keratin associated protein 10-2
LDB1 LIM domain binding 1
LINC00323 long intergenic non-protein coding RNA 323
LINC00515 long intergenic non-protein coding RNA 515
LMAN1 lectin, mannose-binding, 1
LOC285768 uncharacterized LOC285768
LOC399815 chromosome 10 open reading frame 88 pseudogene
LOXL1 lysyl oxidase-like 1
LRRC15 leucine rich repeat containing 15
LRRC7 leucine rich repeat containing 7
LRRN4CL LRRN4 C-terminal like
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LZTS1 leucine zipper, putative tumor suppressor 1
MAPK8 mitogen-activated protein kinase 8
MAST1 microtubule associated serine/threonine kinase 1
MAT1A methionine adenosyltransferase I, alpha
MATN1 matrilin 1, cartilage matrix protein
MBD3 methyl-CpG binding domain protein 3
MCPH1 microcephalin 1
MED12 mediator complex subunit 12
MEGF6 multiple EGF-like-domains 6
METTL11B methyltransferase like 11B
MICB MHC class I polypeptide-related sequence B
MIR1-1HG MIR1-1 host gene
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMP11 matrix metallopeptidase 11
MTUS1 microtubule associated tumor suppressor 1
MVK mevalonate kinase
MXRA8 matrix-remodelling associated 8
MYBPC1 myosin binding protein C, slow type
MYBPC2 myosin binding protein C, fast type
MYOZ2 myozenin 2
NANP N-acetylneuraminic acid phosphatase
NCAM2 neural cell adhesion molecule 2
NCOR2 nuclear receptor corepressor 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NINL ninein-like
NKX2-3 NK2 homeobox 3
NKX3-2 NK3 homeobox 2
NLRP1 NLR family, pyrin domain containing 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOMO1 NODAL modulator 1
NOMO2 NODAL modulator 2
NPHP4 nephronophthisis 4
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NRXN1 neurexin 1
NUAK1 NUAK family, SNF1-like kinase, 1
NUPR1 nuclear protein, transcriptional regulator, 1
NUTM2D NUT family member 2D
OMD osteomodulin
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OR4F6 olfactory receptor, family 4, subfamily F, member 6
OTULIN OTU deubiquitinase with linear linkage specificity
PCDHGB7 protocadherin gamma subfamily B, 7
PDCD11 programmed cell death 11
PEF1 penta-EF-hand domain containing 1
PFKL phosphofructokinase, liver
PGA5 pepsinogen 5, group I (pepsinogen A)
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKDREJ polycystin (PKD) family receptor for egg jelly
PLA2G3 phospholipase A2, group III
POLH polymerase (DNA directed), eta
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POPDC3 popeye domain containing 3
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRDM2 PR domain containing 2, with ZNF domain
PRELP proline/arginine-rich end leucine-rich repeat protein
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PSTK phosphoseryl-tRNA kinase
PTPRF protein tyrosine phosphatase, receptor type, F
PYDC1 PYD (pyrin domain) containing 1
PYDC2 pyrin domain containing 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RDM1 RAD52 motif containing 1
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RFX8 RFX family member 8, lacking RFX DNA binding domain
RGS16 regulator of G-protein signaling 16
RHCE Rh blood group, CcEe antigens
RHD Rh blood group, D antigen
RNF150 ring finger protein 150
RNF165 ring finger protein 165
RPS6KL1 ribosomal protein S6 kinase-like 1
RRP1B ribosomal RNA processing 1B
RUNX3 runt-related transcription factor 3
RYR3 ryanodine receptor 3
SAP30 Sin3A-associated protein, 30kDa
SCARB1 scavenger receptor class B, member 1
SCD5 stearoyl-CoA desaturase 5
SCLT1 sodium channel and clathrin linker 1
SCT secretin
SEC24D SEC24 family member D
SFRP4 secreted frizzled-related protein 4
SH3BGR SH3 domain binding glutamate-rich protein
SH3RF1 SH3 domain containing ring finger 1
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC35E2 solute carrier family 35, member E2
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLX4 SLX4 structure-specific endonuclease subunit
SMAD1 SMAD family member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNN stannin
SNORA47 small nucleolar RNA, H/ACA box 47
SPATA5 spermatogenesis associated 5
SPATC1L spermatogenesis and centriole associated 1-like
SPATS2 spermatogenesis associated, serine-rich 2
SPEN spen family transcriptional repressor
SPHK2 sphingosine kinase 2
SPIDR scaffolding protein involved in DNA repair
SPIRE1 spire-type actin nucleation factor 1
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST7-OT4 ST7 overlapping transcript 4
STX19 syntaxin 19
SUFU suppressor of fused homolog (Drosophila)
SYNDIG1 synapse differentiation inducing 1
SYNPO2 synaptopodin 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAPBP TAP binding protein (tapasin)
TBC1D16 TBC1 domain family, member 16
TBC1D24 TBC1 domain family, member 24
TBC1D26 TBC1 domain family, member 26
TBC1D3H TBC1 domain family, member 3H
TCF3 transcription factor 3
TDRP testis development related protein
TELO2 telomere maintenance 2
TET1 tet methylcytosine dioxygenase 1
THBS2 thrombospondin 2
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLR6 toll-like receptor 6
TLX1 T-cell leukemia homeobox 1
TLX1NB TLX1 neighbor
TMEM133 transmembrane protein 133
TMEM150C transmembrane protein 150C
TMEM200C transmembrane protein 200C
TMEM57 transmembrane protein 57
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNPO2 transportin 2
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TPPP tubulin polymerization promoting protein
TRAPPC11 trafficking protein particle complex 11
TRIM37 tripartite motif containing 37
TSC2 tuberous sclerosis 2
TSPAN9 tetraspanin 9
TWIST2 twist family bHLH transcription factor 2
TXLNA taxilin alpha
TXLNB taxilin beta
TXNDC16 thioredoxin domain containing 16
UHRF1 ubiquitin-like with PHD and ring finger domains 1
ULK1 unc-51 like autophagy activating kinase 1
USP31 ubiquitin specific peptidase 31
UTS2 urotensin 2
UVRAG UV radiation resistance associated
VASH2 vasohibin 2
WNT4 wingless-type MMTV integration site family, member 4
WSCD2 WSC domain containing 2
XKR5 XK, Kell blood group complex subunit-related family, member 5
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XPO7 exportin 7
ZBED3 zinc finger, BED-type containing 3
ZFPM1 zinc finger protein, FOG family member 1
ZNF330 zinc finger protein 330
ZNF414 zinc finger protein 414
ZNF500 zinc finger protein 500
ZNF516 zinc finger protein 516
ZNF532 zinc finger protein 532
ZNF653 zinc finger protein 653
ZNF668 zinc finger protein 668
ZNF774 zinc finger protein 774
ZNF81 zinc finger protein 81
ZNF837 zinc finger protein 837
ZNF843 zinc finger protein 843
ZNF862 zinc finger protein 862

low expression

Symbol Name
RBM45 RNA binding motif protein 45
TMEM87B transmembrane protein 87B
TSC1 tuberous sclerosis 1