Lung squamous cell carcinoma_LUSC_TCGA-85-8580-01A-31R-2403-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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275 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-85-8580-01A-31R-2403-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAA1 aortic aneurysm, familial abdominal 1
AADACL2 arylacetamide deacetylase-like 2
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACAD9 acyl-CoA dehydrogenase family, member 9
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
ADRA2B adrenoceptor alpha 2B
AHDC1 AT hook, DNA binding motif, containing 1
ALOX12B arachidonate 12-lipoxygenase, 12R type
ANKRD19P ankyrin repeat domain 19, pseudogene
ARG1 arginase 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL13B ADP-ribosylation factor-like 13B
ARTN artemin
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASB6 ankyrin repeat and SOCS box containing 6
ASTL astacin-like metallo-endopeptidase (M12 family)
ATG3 autophagy related 3
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BDNF brain-derived neurotrophic factor
BNIPL BCL2/adenovirus E1B 19kD interacting protein like
BORA bora, aurora kinase A activator
BTG3 BTG family, member 3
C11ORF42 chromosome 11 open reading frame 42
C11ORF71 chromosome 11 open reading frame 71
C14ORF178 chromosome 14 open reading frame 178
C15ORF62 chromosome 15 open reading frame 62
C2ORF66 chromosome 2 open reading frame 66
C3ORF62 chromosome 3 open reading frame 62
C5ORF52 chromosome 5 open reading frame 52
C9ORF114 chromosome 9 open reading frame 114
C9ORF142 chromosome 9 open reading frame 142
C9ORF84 chromosome 9 open reading frame 84
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CALML4 calmodulin-like 4
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CASKIN1 CASK interacting protein 1
CASZ1 castor zinc finger 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCAR2 cell cycle and apoptosis regulator 2
CCT6P1 chaperonin containing TCP1, subunit 6 (zeta) pseudogene 1
CDK9 cyclin-dependent kinase 9
CDRT15 CMT1A duplicated region transcript 15
CENPK centromere protein K
CHAF1A chromatin assembly factor 1, subunit A (p150)
CKMT1B creatine kinase, mitochondrial 1B
CLUH clustered mitochondria (cluA/CLU1) homolog
CNFN cornifelin
COMMD4 COMM domain containing 4
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CROCC ciliary rootlet coiled-coil, rootletin
CRYBB2 crystallin, beta B2
CRYBG3 beta-gamma crystallin domain containing 3
CSK c-src tyrosine kinase
CSRP2 cysteine and glycine-rich protein 2
CSTA cystatin A (stefin A)
CUL3 cullin 3
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CXADRP3 coxsackie virus and adenovirus receptor pseudogene 3
CXORF57 chromosome X open reading frame 57
DCK deoxycytidine kinase
DGKA diacylglycerol kinase, alpha 80kDa
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLEC1 deleted in lung and esophageal cancer 1
DLX3 distal-less homeobox 3
DMTN dematin actin binding protein
DPF1 D4, zinc and double PHD fingers family 1
DSG1 desmoglein 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENDOU endonuclease, polyU-specific
EPHA1 EPH receptor A1
EPHB6 EPH receptor B6
ERAS ES cell expressed Ras
ERBB2IP erbb2 interacting protein
EVPL envoplakin
FAM117B family with sequence similarity 117, member B
FAM167A-AS1 FAM167A antisense RNA 1
FAM43A family with sequence similarity 43, member A
FAM71F2 family with sequence similarity 71, member F2
FAM73B family with sequence similarity 73, member B
FAM83C family with sequence similarity 83, member C
FAM83H family with sequence similarity 83, member H
FANCE Fanconi anemia, complementation group E
FETUB fetuin B
FLJ33360 FLJ33360 protein
FOXE1 forkhead box E1
FRMD8 FERM domain containing 8
GALR2 galanin receptor 2
GIF gastric intrinsic factor (vitamin B synthesis)
GLTP glycolipid transfer protein
GMEB2 glucocorticoid modulatory element binding protein 2
GPR6 G protein-coupled receptor 6
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRHL3 grainyhead-like 3 (Drosophila)
H1FX H1 histone family, member X
HCRT hypocretin (orexin) neuropeptide precursor
HDAC4 histone deacetylase 4
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HPSE heparanase
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HYAL3 hyaluronoglucosaminidase 3
IGSF11 immunoglobulin superfamily, member 11
INHBC inhibin, beta C
INTS9 integrator complex subunit 9
IQCB1 IQ motif containing B1
ITPKB inositol-trisphosphate 3-kinase B
IVL involucrin
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough
JPH1 junctophilin 1
KHSRP KH-type splicing regulatory protein
KIAA2018 KIAA2018
KIF21A kinesin family member 21A
KIF7 kinesin family member 7
KLF5 Kruppel-like factor 5 (intestinal)
KLK10 kallikrein-related peptidase 10
KLK14 kallikrein-related peptidase 14
KLRG2 killer cell lectin-like receptor subfamily G, member 2
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT77 keratin 77, type II
KRTDAP keratinocyte differentiation-associated protein
LAD1 ladinin 1
LGI3 leucine-rich repeat LGI family, member 3
LIN54 lin-54 DREAM MuvB core complex component
LIN7C lin-7 homolog C (C. elegans)
LINC00051 long intergenic non-protein coding RNA 51
LINC00176 long intergenic non-protein coding RNA 176
LINC00475 long intergenic non-protein coding RNA 475
LINC01465 long intergenic non-protein coding RNA 1465
LIPF lipase, gastric
LIPM lipase, family member M
LOC100130691 uncharacterized LOC100130691
LOC341056 SUMO1 activating enzyme subunit 1 pseudogene
LOC613037 nuclear pore complex interacting protein pseudogene
LONRF1 LON peptidase N-terminal domain and ring finger 1
LPAR5 lysophosphatidic acid receptor 5
LY6G6C lymphocyte antigen 6 complex, locus G6C
MBD4 methyl-CpG binding domain protein 4
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MOB1B MOB kinase activator 1B
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MPPED1 metallophosphoesterase domain containing 1
MTUS1 microtubule associated tumor suppressor 1
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NDOR1 NADPH dependent diflavin oxidoreductase 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFE2L2 nuclear factor, erythroid 2-like 2
NKPD1 NTPase, KAP family P-loop domain containing 1
NPSR1 neuropeptide S receptor 1
NRADDP neurotrophin receptor associated death domain, pseudogene
NTF3 neurotrophin 3
NUP188 nucleoporin 188kDa
NUP50 nucleoporin 50kDa
NUTM2F NUT family member 2F
NUTM2G NUT family member 2G
NXF2 nuclear RNA export factor 2
NXF5 nuclear RNA export factor 5
ODC1 ornithine decarboxylase 1
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1
OR1K1 olfactory receptor, family 1, subfamily K, member 1
OR4K15 olfactory receptor, family 4, subfamily K, member 15
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B
PAQR3 progestin and adipoQ receptor family member III
PCNT pericentrin
PGA3 pepsinogen 3, group I (pepsinogen A)
PGA4 pepsinogen 4, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PHLDB2 pleckstrin homology-like domain, family B, member 2
PHLDB3 pleckstrin homology-like domain, family B, member 3
PI3 peptidase inhibitor 3, skin-derived
PKP1 plakophilin 1
PLA2G3 phospholipase A2, group III
PLAC8 placenta-specific 8
PLCD1 phospholipase C, delta 1
PLD6 phospholipase D family, member 6
PNPLA1 patatin-like phospholipase domain containing 1
POF1B premature ovarian failure, 1B
PPL periplakin
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRAMEF11 PRAME family member 11
PRAMEF4 PRAME family member 4
PRPF4 pre-mRNA processing factor 4
PRR22 proline rich 22
QSOX2 quiescin Q6 sulfhydryl oxidase 2
RAB6B RAB6B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RAET1K retinoic acid early transcript 1K pseudogene
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGDS ral guanine nucleotide dissociation stimulator
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RANBP3 RAN binding protein 3
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REEP4 receptor accessory protein 4
RNF208 ring finger protein 208
RNF217-AS1 RNF217 antisense RNA 1 (head to head)
RNF219 ring finger protein 219
RNF222 ring finger protein 222
SAGE1 sarcoma antigen 1
SALL3 spalt-like transcription factor 3
SAPCD2 suppressor APC domain containing 2
SCRIB scribbled planar cell polarity protein
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SETD8 SET domain containing (lysine methyltransferase) 8
SGPP2 sphingosine-1-phosphate phosphatase 2
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLC25A42 solute carrier family 25, member 42
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLED1 proteoglycan 3 pseudogene
SLURP1 secreted LY6/PLAUR domain containing 1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNCB synuclein, beta
SNORA62 small nucleolar RNA, H/ACA box 62
SOX15 SRY (sex determining region Y)-box 15
SOX21 SRY (sex determining region Y)-box 21
SPACA4 sperm acrosome associated 4
SPEM1 spermatid maturation 1
SPRR1A small proline-rich protein 1A
SPRR4 small proline-rich protein 4
SPTSSB serine palmitoyltransferase, small subunit B
SREBF1 sterol regulatory element binding transcription factor 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SREK1IP1 SREK1-interacting protein 1
ST7L suppression of tumorigenicity 7 like
STPG1 sperm-tail PG-rich repeat containing 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SURF6 surfeit 6
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TDH L-threonine dehydrogenase (pseudogene)
TET3 tet methylcytosine dioxygenase 3
TGM3 transglutaminase 3
THEM5 thioesterase superfamily member 5
TIAF1 TGFB1-induced anti-apoptotic factor 1
TMPRSS11D transmembrane protease, serine 11D
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOPBP1 topoisomerase (DNA) II binding protein 1
TOR2A torsin family 2, member A
TPRN taperin
TPTEP1 transmembrane phosphatase with tensin homology pseudogene 1
TRAK1 trafficking protein, kinesin binding 1
TRAPPC13 trafficking protein particle complex 13
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM23 tripartite motif containing 23
TRIM35 tripartite motif containing 35
TUBB4B tubulin, beta 4B class IVb
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
ULK3 unc-51 like kinase 3
UMPS uridine monophosphate synthetase
VWA5A von Willebrand factor A domain containing 5A
WFDC5 WAP four-disulfide core domain 5
WNT2B wingless-type MMTV integration site family, member 2B
XPA xeroderma pigmentosum, complementation group A
ZBTB7C zinc finger and BTB domain containing 7C
ZDHHC12 zinc finger, DHHC-type containing 12
ZDHHC3 zinc finger, DHHC-type containing 3
ZMYND19 zinc finger, MYND-type containing 19
ZNF202 zinc finger protein 202
ZNF57 zinc finger protein 57
ZNF595 zinc finger protein 595
ZNF707 zinc finger protein 707
ZNF735 zinc finger protein 735
ZNF782 zinc finger protein 782

low expression

Symbol Name
FRG1 FSHD region gene 1
SETD5 SET domain containing 5
THUMPD3 THUMP domain containing 3