Lung squamous cell carcinoma_LUSC_TCGA-94-8035-01A-11R-2247-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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330 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-94-8035-01A-11R-2247-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AASDH aminoadipate-semialdehyde dehydrogenase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ABHD8 abhydrolase domain containing 8
ACLY ATP citrate lyase
ADGRL1 adhesion G protein-coupled receptor L1
AHDC1 AT hook, DNA binding motif, containing 1
ALKBH2 alkB, alkylation repair homolog 2 (E. coli)
ALKBH5 AlkB family member 5, RNA demethylase
ANKRD17 ankyrin repeat domain 17
ANKRD39 ankyrin repeat domain 39
ANKRD42 ankyrin repeat domain 42
ANO7 anoctamin 7
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APC2 adenomatosis polyposis coli 2
AREG amphiregulin
ARHGAP5-AS1 ARHGAP5 antisense RNA 1 (head to head)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARID1A AT rich interactive domain 1A (SWI-like)
ARMC7 armadillo repeat containing 7
ARRDC4 arrestin domain containing 4
ASPG asparaginase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BCLAF1 BCL2-associated transcription factor 1
BRI3BP BRI3 binding protein
BSG basigin (Ok blood group)
BTC betacellulin
C14ORF80 chromosome 14 open reading frame 80
C17ORF85 chromosome 17 open reading frame 85
C19ORF24 chromosome 19 open reading frame 24
C19ORF25 chromosome 19 open reading frame 25
C19ORF48 chromosome 19 open reading frame 48
C21ORF59 chromosome 21 open reading frame 59
C2ORF16 chromosome 2 open reading frame 16
C7ORF66 chromosome 7 open reading frame 66
C7ORF71 chromosome 7 open reading frame 71
C8ORF74 chromosome 8 open reading frame 74
C9ORF69 chromosome 9 open reading frame 69
CABS1 calcium-binding protein, spermatid-specific 1
CALR calreticulin
CBLN2 cerebellin 2 precursor
CBWD1 COBW domain containing 1
CBWD5 COBW domain containing 5
CCDC137 coiled-coil domain containing 137
CCNI cyclin I
CDC34 cell division cycle 34
CDH24 cadherin 24, type 2
CDX4 caudal type homeobox 4
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CENPC centromere protein C
CEP135 centrosomal protein 135kDa
CHMP7 charged multivesicular body protein 7
CIRBP-AS1 CIRBP antisense RNA 1
CKMT1B creatine kinase, mitochondrial 1B
CLOCK clock circadian regulator
CNGB3 cyclic nucleotide gated channel beta 3
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CPT1C carnitine palmitoyltransferase 1C
CSRP2 cysteine and glycine-rich protein 2
CYB5D1 cytochrome b5 domain containing 1
DANCR differentiation antagonizing non-protein coding RNA
DBX2 developing brain homeobox 2
DCK deoxycytidine kinase
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DMRTA1 DMRT-like family A1
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DSC2 desmocollin 2
DSC3 desmocollin 3
DSEL dermatan sulfate epimerase-like
DSG3 desmoglein 3
DUSP5P1 dual specificity phosphatase 5 pseudogene 1
E2F2 E2F transcription factor 2
ECE2 endothelin converting enzyme 2
EFS embryonal Fyn-associated substrate
EIF1AD eukaryotic translation initiation factor 1A domain containing
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5A eukaryotic translation initiation factor 5A
EIF5AL1 eukaryotic translation initiation factor 5A-like 1
ELOF1 elongation factor 1 homolog (S. cerevisiae)
EMC1 ER membrane protein complex subunit 1
EMC6 ER membrane protein complex subunit 6
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPHA2 EPH receptor A2
EPHA4 EPH receptor A4
ERP29 endoplasmic reticulum protein 29
EXOC1 exocyst complex component 1
EXTL3 exostosin-like glycosyltransferase 3
FAM111B family with sequence similarity 111, member B
FASN fatty acid synthase
FEM1A fem-1 homolog a (C. elegans)
FGF11 fibroblast growth factor 11
FIP1L1 factor interacting with PAPOLA and CPSF1
FOXK2 forkhead box K2
FTLP10 ferritin, light polypeptide pseudogene 10
FTSJ3 FtsJ homolog 3 (E. coli)
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GAGE1 G antigen 1
GAGE10 G antigen 10
GAGE2B G antigen 2B
GAGE2C G antigen 2C
GAGE2D G antigen 2D
GAGE4 G antigen 4
GAMT guanidinoacetate N-methyltransferase
GBP6 guanylate binding protein family, member 6
GEMIN4 gem (nuclear organelle) associated protein 4
GGCX gamma-glutamyl carboxylase
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1
GRB2 growth factor receptor-bound protein 2
GRSF1 G-rich RNA sequence binding factor 1
GRWD1 glutamate-rich WD repeat containing 1
GSK3A glycogen synthase kinase 3 alpha
GTF3A general transcription factor IIIA
GUSBP1 glucuronidase, beta pseudogene 1
H3F3B H3 histone, family 3B (H3.3B)
H3F3C H3 histone, family 3C
HEXIM1 hexamethylene bis-acetamide inducible 1
HHIPL1 HHIP-like 1
HIST1H2BH histone cluster 1, H2bh
HIST1H3C histone cluster 1, H3c
HIST1H3J histone cluster 1, H3j
HIST1H4L histone cluster 1, H4l
HMGN1 high mobility group nucleosome binding domain 1
HMGN5 high mobility group nucleosome binding domain 5
HMSD histocompatibility (minor) serpin domain containing
HPYR1 Helicobacter pylori responsive 1 (non-protein coding)
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
ICMT isoprenylcysteine carboxyl methyltransferase
IL31 interleukin 31
KDF1 keratinocyte differentiation factor 1
KHSRP KH-type splicing regulatory protein
KISS1R KISS1 receptor
KITLG KIT ligand
KLF16 Kruppel-like factor 16
KRI1 KRI1 homolog (S. cerevisiae)
KRT19 keratin 19, type I
KRTAP12-1 keratin associated protein 12-1
KRTAP9-2 keratin associated protein 9-2
KRTAP9-4 keratin associated protein 9-4
LALBA lactalbumin, alpha-
LCE1B late cornified envelope 1B
LINC00160 long intergenic non-protein coding RNA 160
LINC00652 long intergenic non-protein coding RNA 652
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LNX2 ligand of numb-protein X 2
MAGEA1 melanoma antigen family A1
MAGEA10 melanoma antigen family A10
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK13 mitogen-activated protein kinase 13
MARK2 MAP/microtubule affinity-regulating kinase 2
MBD3 methyl-CpG binding domain protein 3
MED16 mediator complex subunit 16
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD2B major facilitator superfamily domain containing 2B
MFSD6L major facilitator superfamily domain containing 6-like
MGAT4C MGAT4 family, member C
MGC2889 uncharacterized protein MGC2889
MIER2 mesoderm induction early response 1, family member 2
MOB1B MOB kinase activator 1B
MRGPRX1 MAS-related GPR, member X1
MRPL39 mitochondrial ribosomal protein L39
MTIF3 mitochondrial translational initiation factor 3
MTMR9 myotubularin related protein 9
MUM1L1 melanoma associated antigen (mutated) 1-like 1
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAIF1 nuclear apoptosis inducing factor 1
NAP1L6 nucleosome assembly protein 1-like 6
NARF nuclear prelamin A recognition factor
NCL nucleolin
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NMU neuromedin U
NOA1 nitric oxide associated 1
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8
NUP54 nucleoporin 54kDa
ODC1 ornithine decarboxylase 1
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
OR7D2 olfactory receptor, family 7, subfamily D, member 2
P4HB prolyl 4-hydroxylase, beta polypeptide
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PANK4 pantothenate kinase 4
PARD6G par-6 family cell polarity regulator gamma
PCDHB3 protocadherin beta 3
PFKL phosphofructokinase, liver
PGAM2 phosphoglycerate mutase 2 (muscle)
PGK2 phosphoglycerate kinase 2
PHF23 PHD finger protein 23
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
PLD6 phospholipase D family, member 6
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POU4F1 POU class 4 homeobox 1
PPAN-P2RY11 PPAN-P2RY11 readthrough
PPAT phosphoribosyl pyrophosphate amidotransferase
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PQLC2 PQ loop repeat containing 2
PRDM4 PR domain containing 4
PRKCSH protein kinase C substrate 80K-H
PRMT2 protein arginine methyltransferase 2
PRSS16 protease, serine, 16 (thymus)
PUS3 pseudouridylate synthase 3
PUSL1 pseudouridylate synthase-like 1
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB2B RAB2B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RABIF RAB interacting factor
RASL11A RAS-like, family 11, member A
RBM44 RNA binding motif protein 44
RCC2 regulator of chromosome condensation 2
REEP4 receptor accessory protein 4
RHOV ras homolog family member V
RIC8B RIC8 guanine nucleotide exchange factor B
RITA1 RBPJ interacting and tubulin associated 1
RNF126 ring finger protein 126
RNF167 ring finger protein 167
RNF32 ring finger protein 32
RPL10L ribosomal protein L10-like
RPL21 ribosomal protein L21
RPP25 ribonuclease P/MRP 25kDa subunit
RPS2P32 ribosomal protein S2 pseudogene 32
RRM2 ribonucleotide reductase M2
RRP1B ribosomal RNA processing 1B
RUSC1 RUN and SH3 domain containing 1
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCAMP4 secretory carrier membrane protein 4
SCARB2 scavenger receptor class B, member 2
SCFD2 sec1 family domain containing 2
SDAD1 SDA1 domain containing 1
SEPT11 septin 11
SERBP1 SERPINE1 mRNA binding protein 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFPQ splicing factor proline/glutamine-rich
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC25A41 solute carrier family 25, member 41
SLC25A52 solute carrier family 25, member 52
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC51A solute carrier family 51, alpha subunit
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SNORA55 small nucleolar RNA, H/ACA box 55
SOWAHB sosondowah ankyrin repeat domain family member B
SPAG7 sperm associated antigen 7
SPATC1L spermatogenesis and centriole associated 1-like
SPPL3 signal peptide peptidase like 3
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2A small proline-rich protein 2A
SPRR2D small proline-rich protein 2D
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
SRP72 signal recognition particle 72kDa
SRSF4 serine/arginine-rich splicing factor 4
STK35 serine/threonine kinase 35
STRADA STE20-related kinase adaptor alpha
STXBP5 syntaxin binding protein 5 (tomosyn)
SUMO3 small ubiquitin-like modifier 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBCCD1 TBCC domain containing 1
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TDG thymine-DNA glycosylase
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TFF2 trefoil factor 2
TGM3 transglutaminase 3
THAP6 THAP domain containing 6
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TLCD1 TLC domain containing 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM102 transmembrane protein 102
TMEM201 transmembrane protein 201
TMEM37 transmembrane protein 37
TMEM41A transmembrane protein 41A
TMPRSS11A transmembrane protease, serine 11A
TMPRSS11D transmembrane protease, serine 11D
TMPRSS11F transmembrane protease, serine 11F
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TMUB1 transmembrane and ubiquitin-like domain containing 1
TMX3 thioredoxin-related transmembrane protein 3
TNNI1 troponin I type 1 (skeletal, slow)
TRA2B transformer 2 beta homolog (Drosophila)
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
UBA6 ubiquitin-like modifier activating enzyme 6
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
UHRF1 ubiquitin-like with PHD and ring finger domains 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
ULK3 unc-51 like kinase 3
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
UPK1B uroplakin 1B
USO1 USO1 vesicle transport factor
USP46 ubiquitin specific peptidase 46
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
WFDC11 WAP four-disulfide core domain 11
WIBG within bgcn homolog (Drosophila)
WISP3 WNT1 inducible signaling pathway protein 3
WRAP53 WD repeat containing, antisense to TP53
WRB tryptophan rich basic protein
XPO7 exportin 7
YTHDC1 YTH domain containing 1
ZBTB11 zinc finger and BTB domain containing 11
ZIC5 Zic family member 5
ZNF544 zinc finger protein 544
ZNF556 zinc finger protein 556
ZNF584 zinc finger protein 584
ZNF77 zinc finger protein 77
ZNF883 zinc finger protein 883

low expression

Symbol Name
CREBBP CREB binding protein
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit