Lung squamous cell carcinoma_LUSC_TCGA-96-7545-01A-21R-2045-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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206 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-96-7545-01A-21R-2045-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACOT13 acyl-CoA thioesterase 13
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADGRG4 adhesion G protein-coupled receptor G4
AFTPH aftiphilin
AKR1C2 aldo-keto reductase family 1, member C2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGAP28 Rho GTPase activating protein 28
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL5A ADP-ribosylation factor-like 5A
ARSG arylsulfatase G
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATRN attractin
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BOD1L1 biorientation of chromosomes in cell division 1-like 1
C17ORF105 chromosome 17 open reading frame 105
C1D C1D nuclear receptor corepressor
C6ORF10 chromosome 6 open reading frame 10
C8B complement component 8, beta polypeptide
CALN1 calneuron 1
CCNDBP1 cyclin D-type binding-protein 1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH13 cadherin 13
CEP68 centrosomal protein 68kDa
CERS6 ceramide synthase 6
CHRM3 cholinergic receptor, muscarinic 3
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CNOT6L CCR4-NOT transcription complex, subunit 6-like
COPS2 COP9 signalosome subunit 2
CPA3 carboxypeptidase A3 (mast cell)
CPEB2 cytoplasmic polyadenylation element binding protein 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRHBP corticotropin releasing hormone binding protein
CRIPT cysteine-rich PDZ-binding protein
CRYBA4 crystallin, beta A4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DSP desmoplakin
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
DYNLT3 dynein, light chain, Tctex-type 3
EDN1 endothelin 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPCAM epithelial cell adhesion molecule
EXOC6B exocyst complex component 6B
FAM114A1 family with sequence similarity 114, member A1
FAM117B family with sequence similarity 117, member B
FAM13A family with sequence similarity 13, member A
FAM210B family with sequence similarity 210, member B
FAM8A1 family with sequence similarity 8, member A1
FBXO11 F-box protein 11
FEM1B fem-1 homolog b (C. elegans)
FETUB fetuin B
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOXN2 forkhead box N2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLIPR1L2 GLI pathogenesis-related 1 like 2
GMPS guanine monphosphate synthase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GPI glucose-6-phosphate isomerase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HK2 hexokinase 2
HLF hepatic leukemia factor
HP haptoglobin
HPS3 Hermansky-Pudlak syndrome 3
HPSE heparanase
IER3IP1 immediate early response 3 interacting protein 1
IGSF10 immunoglobulin superfamily, member 10
IMPAD1 inositol monophosphatase domain containing 1
IRS2 insulin receptor substrate 2
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDM1B lysine (K)-specific demethylase 1B
KDM7A lysine (K)-specific demethylase 7A
KDSR 3-ketodihydrosphingosine reductase
KIF13A kinesin family member 13A
KIF5B kinesin family member 5B
KLF3 Kruppel-like factor 3 (basic)
KLHL5 kelch-like family member 5
KPNA4 karyopherin alpha 4 (importin alpha 3)
LAMP2 lysosomal-associated membrane protein 2
LIAS lipoic acid synthetase
LRRTM1 leucine rich repeat transmembrane neuronal 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP2K5 mitogen-activated protein kinase kinase 5
MBD2 methyl-CpG binding domain protein 2
MBNL1 muscleblind-like splicing regulator 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCFD2 multiple coagulation factor deficiency 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD1 major facilitator superfamily domain containing 1
MIF4GD MIF4G domain containing
MMRN1 multimerin 1
MOB1A MOB kinase activator 1A
MORC3 MORC family CW-type zinc finger 3
MRPL19 mitochondrial ribosomal protein L19
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTIF2 mitochondrial translational initiation factor 2
NBEAP1 neurobeachin pseudogene 1
NEBL nebulette
NELL1 NEL-like 1 (chicken)
NMD3 NMD3 ribosome export adaptor
NOS1 nitric oxide synthase 1 (neuronal)
NPY5R neuropeptide Y receptor Y5
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
OPA1 optic atrophy 1 (autosomal dominant)
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAQR3 progestin and adipoQ receptor family member III
PARD3 par-3 family cell polarity regulator
PCDHGB7 protocadherin gamma subfamily B, 7
PCYOX1 prenylcysteine oxidase 1
PDS5A PDS5 cohesin associated factor A
PGAP1 post-GPI attachment to proteins 1
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAC8 placenta-specific 8
PLCH1 phospholipase C, eta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLS3 plastin 3
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1R21 protein phosphatase 1, regulatory subunit 21
PPP1R2P1 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1
PPP1R2P3 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
RANBP2 RAN binding protein 2
RAP2B RAP2B, member of RAS oncogene family
RCAN1 regulator of calcineurin 1
RELL1 RELT-like 1
RNF13 ring finger protein 13
RNF149 ring finger protein 149
RPL22L1 ribosomal protein L22-like 1
RPL23P8 ribosomal protein L23 pseudogene 8
RPS27A ribosomal protein S27a
SALL3 spalt-like transcription factor 3
SCARB2 scavenger receptor class B, member 2
SEC31A SEC31 homolog A (S. cerevisiae)
SEPT11 septin 11
SERP1 stress-associated endoplasmic reticulum protein 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLAIN2 SLAIN motif family, member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC35F3 solute carrier family 35, member F3
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOCS2 suppressor of cytokine signaling 2
SOCS5 suppressor of cytokine signaling 5
SOWAHB sosondowah ankyrin repeat domain family member B
SPIN2B spindlin family, member 2B
SSR1 signal sequence receptor, alpha
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAMBP STAM binding protein
STON1 stonin 1
TCF4 transcription factor 4
TDP2 tyrosyl-DNA phosphodiesterase 2
TDRP testis development related protein
TM4SF1 transmembrane 4 L six family member 1
TMEM209 transmembrane protein 209
TMEM33 transmembrane protein 33
TMEM41A transmembrane protein 41A
TMEM87A transmembrane protein 87A
TMOD2 tropomodulin 2 (neuronal)
TMPRSS11F transmembrane protease, serine 11F
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TPI1P3 triosephosphate isomerase 1 pseudogene 3
TPMT thiopurine S-methyltransferase
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSPAN18 tetraspanin 18
TTC7A tetratricopeptide repeat domain 7A
UBE3A ubiquitin protein ligase E3A
UGDH UDP-glucose 6-dehydrogenase
USP6NL USP6 N-terminal like
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
ZDHHC3 zinc finger, DHHC-type containing 3
ZNF507 zinc finger protein 507
ZNF556 zinc finger protein 556
ZNF800 zinc finger protein 800

low expression

Symbol Name
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
MUS81 MUS81 structure-specific endonuclease subunit