Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
Similar Terms
Downloads & Tools


449 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ADAM33 ADAM metallopeptidase domain 33
ADD1 adducin 1 (alpha)
ADRA2C adrenoceptor alpha 2C
ADSSL1 adenylosuccinate synthase like 1
AHNAK2 AHNAK nucleoprotein 2
AIM1 absent in melanoma 1
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
ALLC allantoicase
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD11 ankyrin repeat domain 11
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APC2 adenomatosis polyposis coli 2
ARHGAP39 Rho GTPase activating protein 39
ARMC5 armadillo repeat containing 5
ARSD arylsulfatase D
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPG asparaginase
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATXN1 ataxin 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
BCO2 beta-carotene oxygenase 2
BEND3 BEN domain containing 3
BEND5 BEN domain containing 5
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BMP8B bone morphogenetic protein 8b
BTBD3 BTB (POZ) domain containing 3
C11ORF71 chromosome 11 open reading frame 71
C11ORF94 chromosome 11 open reading frame 94
C11ORF95 chromosome 11 open reading frame 95
C15ORF56 chromosome 15 open reading frame 56
C16ORF46 chromosome 16 open reading frame 46
C16ORF58 chromosome 16 open reading frame 58
C17ORF97 chromosome 17 open reading frame 97
C19ORF73 chromosome 19 open reading frame 73
C1ORF226 chromosome 1 open reading frame 226
C20ORF194 chromosome 20 open reading frame 194
C20ORF195 chromosome 20 open reading frame 195
C22ORF24 chromosome 22 open reading frame 24
C3ORF20 chromosome 3 open reading frame 20
C3ORF22 chromosome 3 open reading frame 22
C3ORF58 chromosome 3 open reading frame 58
C7ORF69 chromosome 7 open reading frame 69
C9ORF163 chromosome 9 open reading frame 163
C9ORF172 chromosome 9 open reading frame 172
C9ORF69 chromosome 9 open reading frame 69
CA5BP1 carbonic anhydrase VB pseudogene 1
CACFD1 calcium channel flower domain containing 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACTIN cactin, spliceosome C complex subunit
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPNS2 calpain, small subunit 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBX6 chromobox homolog 6
CCDC115 coiled-coil domain containing 115
CD276 CD276 molecule
CDC25B cell division cycle 25B
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CELF5 CUGBP, Elav-like family member 5
CENPB centromere protein B, 80kDa
CHPF chondroitin polymerizing factor
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CILP2 cartilage intermediate layer protein 2
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COL20A1 collagen, type XX, alpha 1
COL6A4P2 collagen, type VI, alpha 4 pseudogene 2
COL9A2 collagen, type IX, alpha 2
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
COPG1 coatomer protein complex, subunit gamma 1
CPLX1 complexin 1
CRIPAK cysteine-rich PAK1 inhibitor
CRYBA2 crystallin, beta A2
CRYGS crystallin, gamma S
CSRP2 cysteine and glycine-rich protein 2
CTBP1 C-terminal binding protein 1
CTBP1-AS2 CTBP1 antisense RNA 2 (head to head)
CTNND1 catenin (cadherin-associated protein), delta 1
CTPS1 CTP synthase 1
CYCSP52 cytochrome c, somatic pseudogene 52
DACT2 dishevelled-binding antagonist of beta-catenin 2
DAZL deleted in azoospermia-like
DBIL5P diazepam binding inhibitor-like 5, pseudogene
DDRGK1 DDRGK domain containing 1
DGKQ diacylglycerol kinase, theta 110kDa
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DPPA5 developmental pluripotency associated 5
DSP desmoplakin
DTNA dystrobrevin, alpha
EBF4 early B-cell factor 4
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPHA4 EPH receptor A4
EPPK1 epiplakin 1
ERICH6 glutamate-rich 6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETV5 ets variant 5
FAM120B family with sequence similarity 120B
FAM127C family with sequence similarity 127, member C
FAM160A2 family with sequence similarity 160, member A2
FAM168B family with sequence similarity 168, member B
FAM181B family with sequence similarity 181, member B
FAM193A family with sequence similarity 193, member A
FAM43A family with sequence similarity 43, member A
FAM46D family with sequence similarity 46, member D
FAM90A1 family with sequence similarity 90, member A1
FBXL19 F-box and leucine-rich repeat protein 19
FBXL7 F-box and leucine-rich repeat protein 7
FBXO47 F-box protein 47
FGFRL1 fibroblast growth factor receptor-like 1
FLJ16779 uncharacterized LOC100192386
FLJ30679 uncharacterized protein FLJ30679
FLJ34503 uncharacterized FLJ34503
FLJ37453 uncharacterized LOC729614
FLYWCH1 FLYWCH-type zinc finger 1
FMO4 flavin containing monooxygenase 4
FOXK1 forkhead box K1
FOXL2 forkhead box L2
FOXP2 forkhead box P2
FSD2 fibronectin type III and SPRY domain containing 2
FTHL17 ferritin, heavy polypeptide-like 17
FURIN furin (paired basic amino acid cleaving enzyme)
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAK cyclin G associated kinase
GALNS galactosamine (N-acetyl)-6-sulfatase
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GATSL3 GATS protein-like 3
GEMIN8 gem (nuclear organelle) associated protein 8
GGN gametogenetin
GLB1L galactosidase, beta 1-like
GLRA2 glycine receptor, alpha 2
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GOLGA3 golgin A3
GOLGA6A golgin A6 family, member A
GOLGA6B golgin A6 family, member B
GOLGB1 golgin B1
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
GPNMB glycoprotein (transmembrane) nmb
GPR149 G protein-coupled receptor 149
GPR150 G protein-coupled receptor 150
GPR26 G protein-coupled receptor 26
GPR27 G protein-coupled receptor 27
GRM5 glutamate receptor, metabotropic 5
GSTTP2 glutathione S-transferase theta pseudogene 2
GTF2A1L general transcription factor IIA, 1-like
HAO2 hydroxyacid oxidase 2 (long chain)
HAUS3 HAUS augmin-like complex, subunit 3
HCG4 HLA complex group 4 (non-protein coding)
HCRTR1 hypocretin (orexin) receptor 1
HDAC6 histone deacetylase 6
HDLBP high density lipoprotein binding protein
HGFAC HGF activator
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HMG20B high mobility group 20B
HOOK3 hook microtubule-tethering protein 3
HSPA1L heat shock 70kDa protein 1-like
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
HTT huntingtin
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IDUA iduronidase, alpha-L-
IFITM5 interferon induced transmembrane protein 5
IGSF11 immunoglobulin superfamily, member 11
IGSF8 immunoglobulin superfamily, member 8
IL9 interleukin 9
INTS4P1 integrator complex subunit 4 pseudogene 1
IQSEC2 IQ motif and Sec7 domain 2
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
JAG1 jagged 1
JRK Jrk homolog (mouse)
KAT6A K(lysine) acetyltransferase 6A
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KDM5C lysine (K)-specific demethylase 5C
KERA keratocan
KGFLP2 keratinocyte growth factor-like protein 2
KIAA0232 KIAA0232
KIAA1024 KIAA1024
KLHL36 kelch-like family member 36
KLKP1 kallikrein pseudogene 1
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6C keratin 6C, type II
KY kyphoscoliosis peptidase
LALBA lactalbumin, alpha-
LCE1B late cornified envelope 1B
LEKR1 leucine, glutamate and lysine rich 1
LHCGR luteinizing hormone/choriogonadotropin receptor
LINC00167 long intergenic non-protein coding RNA 167
LINC00319 long intergenic non-protein coding RNA 319
LINC00476 long intergenic non-protein coding RNA 476
LINC01465 long intergenic non-protein coding RNA 1465
LINC01599 long intergenic non-protein coding RNA 1599
LMNTD2 lamin tail domain containing 2
LOC100270804 uncharacterized LOC100270804
LOC143188 uncharacterized LOC143188
LOC283731 uncharacterized LOC283731
LOC283856 uncharacterized LOC283856
LOC284661 uncharacterized LOC284661
LOC285593 uncharacterized LOC285593
LOC93622 Morf4 family associated protein 1-like 1 pseudogene
LPA lipoprotein, Lp(a)
LRP3 low density lipoprotein receptor-related protein 3
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC24 leucine rich repeat containing 24
LRRC41 leucine rich repeat containing 41
LRRC4C leucine rich repeat containing 4C
LRRC56 leucine rich repeat containing 56
LUZP2 leucine zipper protein 2
LYNX1 Ly6/neurotoxin 1
MACF1 microtubule-actin crosslinking factor 1
MAEA macrophage erythroblast attacher
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEB18 melanoma antigen family B18
MAGED1 melanoma antigen family D1
MAGED4B melanoma antigen family D4B
MAGEE2 melanoma antigen family E2
MAN2B2 mannosidase, alpha, class 2B, member 2
MAP10 microtubule-associated protein 10
MAP2K5 mitogen-activated protein kinase kinase 5
MARVELD3 MARVEL domain containing 3
MAVS mitochondrial antiviral signaling protein
MBD3L2 methyl-CpG binding domain protein 3-like 2
MCHR2 melanin-concentrating hormone receptor 2
MEX3B mex-3 RNA binding family member B
MEX3D mex-3 RNA binding family member D
MIER2 mesoderm induction early response 1, family member 2
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLYCD malonyl-CoA decarboxylase
MMP10 matrix metallopeptidase 10
MMP23A matrix metallopeptidase 23A (pseudogene)
MN1 meningioma (disrupted in balanced translocation) 1
MON1B MON1 secretory trafficking family member B
MRFAP1L1 Morf4 family associated protein 1-like 1
MRGPRE MAS-related GPR, member E
MROH1 maestro heat-like repeat family member 1
MSANTD1 Myb/SANT-like DNA-binding domain containing 1
MTCL1 microtubule crosslinking factor 1
MUM1 melanoma associated antigen (mutated) 1
MXD4 MAX dimerization protein 4
MXRA5 matrix-remodelling associated 5
MYOD1 myogenic differentiation 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAP1L6 nucleosome assembly protein 1-like 6
NDRG4 NDRG family member 4
NELFA negative elongation factor complex member A
NFYC nuclear transcription factor Y, gamma
NHLH1 nescient helix loop helix 1
NKAIN4 Na+/K+ transporting ATPase interacting 4
NLRP6 NLR family, pyrin domain containing 6
NOP14-AS1 NOP14 antisense RNA 1
NOXA1 NADPH oxidase activator 1
NPR3 natriuretic peptide receptor 3
NSG1 neuron specific gene family member 1
NUTM2D NUT family member 2D
NXF2 nuclear RNA export factor 2
NXF5 nuclear RNA export factor 5
NXNL2 nucleoredoxin-like 2
NXT2 nuclear transport factor 2-like export factor 2
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1
OR2A4 olfactory receptor, family 2, subfamily A, member 4
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OR52E8 olfactory receptor, family 52, subfamily E, member 8
OR56A5 olfactory receptor, family 56, subfamily A, member 5
OR5P2 olfactory receptor, family 5, subfamily P, member 2
OR5T2 olfactory receptor, family 5, subfamily T, member 2
ORAI3 ORAI calcium release-activated calcium modulator 3
OXT oxytocin/neurophysin I prepropeptide
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P3H1 prolyl 3-hydroxylase 1
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PANK2 pantothenate kinase 2
PATE3 prostate and testis expressed 3
PCDHA2 protocadherin alpha 2
PCDHB12 protocadherin beta 12
PCDHB14 protocadherin beta 14
PCDHB4 protocadherin beta 4
PCED1A PC-esterase domain containing 1A
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCGF3 polycomb group ring finger 3
PCSK4 proprotein convertase subtilisin/kexin type 4
PDIA4 protein disulfide isomerase family A, member 4
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX6 peroxisomal biogenesis factor 6
PGK2 phosphoglycerate kinase 2
PGM2L1 phosphoglucomutase 2-like 1
PHRF1 PHD and ring finger domains 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEC plectin
PLK5 polo-like kinase 5
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1
PNMA5 paraneoplastic Ma antigen family member 5
POLN polymerase (DNA directed) nu
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B
PPARA peroxisome proliferator-activated receptor alpha
PPCS phosphopantothenoylcysteine synthetase
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PRAMEF14 PRAME family member 14
PRAMEF2 PRAME family member 2
PRAMEF22 PRAME family member 22
PRKX protein kinase, X-linked
PROSC proline synthetase co-transcribed homolog (bacterial)
PRR15 proline rich 15
PRSS16 protease, serine, 16 (thymus)
PSPN persephin
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRF protein tyrosine phosphatase, receptor type, F
PYDC2 pyrin domain containing 2
RAB43 RAB43, member RAS oncogene family
RAB6C RAB6C, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAD51AP2 RAD51 associated protein 2
RAI2 retinoic acid induced 2
RAX retina and anterior neural fold homeobox
RBMXL3 RNA binding motif protein, X-linked-like 3
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RGS12 regulator of G-protein signaling 12
RHO rhodopsin
RIMS3 regulating synaptic membrane exocytosis 3
RLF rearranged L-myc fusion
RNF170 ring finger protein 170
RNF4 ring finger protein 4
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RRBP1 ribosome binding protein 1
RYR3 ryanodine receptor 3
SAG S-antigen; retina and pineal gland (arrestin)
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCN3B sodium channel, voltage gated, type III beta subunit
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SHBG sex hormone-binding globulin
SHPK sedoheptulokinase
SHROOM2 shroom family member 2
SIX3 SIX homeobox 3
SKOR1 SKI family transcriptional corepressor 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A18 solute carrier family 22, member 18
SLC22A23 solute carrier family 22, member 23
SLC25A34 solute carrier family 25, member 34
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLITRK3 SLIT and NTRK-like family, member 3
SLX4IP SLX4 interacting protein
SMIM10L2A small integral membrane protein 10 like 2A
SMIM10L2B small integral membrane protein 10 like 2B
SMIM19 small integral membrane protein 19
SNORD116-4 small nucleolar RNA, C/D box 116-4
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1
SOX11 SRY (sex determining region Y)-box 11
SOX3 SRY (sex determining region Y)-box 3
SPEM1 spermatid maturation 1
SPNS1 spinster homolog 1 (Drosophila)
SPRYD3 SPRY domain containing 3
SRCAP Snf2-related CREBBP activator protein
SSPO SCO-spondin
SSTR5 somatostatin receptor 5
ST20-AS1 ST20 antisense RNA 1
ST7L suppression of tumorigenicity 7 like
STK35 serine/threonine kinase 35
SYNGR3 synaptogyrin 3
SYT9 synaptotagmin IX
SZT2 seizure threshold 2 homolog (mouse)
TADA2B transcriptional adaptor 2B
TAS2R10 taste receptor, type 2, member 10
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBC1D14 TBC1 domain family, member 14
TBC1D21 TBC1 domain family, member 21
TCTE3 t-complex-associated-testis-expressed 3
TEKT3 tektin 3
TG thyroglobulin
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TMEM132B transmembrane protein 132B
TMEM132C transmembrane protein 132C
TMEM229A transmembrane protein 229A
TMEM31 transmembrane protein 31
TMEM88B transmembrane protein 88B
TMPRSS7 transmembrane protease, serine 7
TNIP2 TNFAIP3 interacting protein 2
TOLLIP toll interacting protein
TP53TG3B TP53 target 3B
TPGS1 tubulin polyglutamylase complex subunit 1
TPRX1 tetra-peptide repeat homeobox 1
TRAPPC2 trafficking protein particle complex 2
TRIM43 tripartite motif containing 43
TRIM64 tripartite motif containing 64
TRIM67 tripartite motif containing 67
TSGA13 testis specific, 13
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBOX5 U-box domain containing 5
ULBP3 UL16 binding protein 3
UPP2 uridine phosphorylase 2
UVSSA UV-stimulated scaffold protein A
VCX variable charge, X-linked
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VWA5A von Willebrand factor A domain containing 5A
VWC2 von Willebrand factor C domain containing 2
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR3 WD repeat domain 3
WNT2B wingless-type MMTV integration site family, member 2B
WWOX WW domain containing oxidoreductase
XAB2 XPA binding protein 2
XIST X inactive specific transcript (non-protein coding)
YIPF7 Yip1 domain family, member 7
ZBED9 zinc finger, BED-type containing 9
ZBTB22 zinc finger and BTB domain containing 22
ZBTB3 zinc finger and BTB domain containing 3
ZBTB49 zinc finger and BTB domain containing 49
ZC3H18 zinc finger CCCH-type containing 18
ZC3H3 zinc finger CCCH-type containing 3
ZC3H6 zinc finger CCCH-type containing 6
ZFP41 ZFP41 zinc finger protein
ZFP69 ZFP69 zinc finger protein
ZFP69B ZFP69 zinc finger protein B
ZMPSTE24 zinc metallopeptidase STE24
ZNF213 zinc finger protein 213
ZNF214 zinc finger protein 214
ZNF517 zinc finger protein 517
ZNF528 zinc finger protein 528
ZNF532 zinc finger protein 532
ZNF610 zinc finger protein 610
ZNF611 zinc finger protein 611
ZNF646 zinc finger protein 646
ZNF665 zinc finger protein 665
ZNF668 zinc finger protein 668
ZNF684 zinc finger protein 684
ZNF688 zinc finger protein 688
ZNF703 zinc finger protein 703
ZNF747 zinc finger protein 747
ZNF785 zinc finger protein 785
ZNF843 zinc finger protein 843
ZNF880 zinc finger protein 880

low expression

Symbol Name
C12ORF43 chromosome 12 open reading frame 43