Lymphangioleiomyomatosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

197 genes co-occuring with the disease Lymphangioleiomyomatosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
TSC2 tuberous sclerosis 2 3.675
TSC1 tuberous sclerosis 1 3.353
MTOR mechanistic target of rapamycin (serine/threonine kinase) 3.106
VEGFD vascular endothelial growth factor D 3.094
RHEB Ras homolog enriched in brain 2.828
FLCN folliculin 2.721
TBC1D7 TBC1 domain family, member 7 2.566
TFE3 transcription factor binding to IGHM enhancer 3 2.447
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 2.406
RPTOR regulatory associated protein of MTOR, complex 1 2.301
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.273
FKBP1A FK506 binding protein 1A, 12kDa 2.266
RASA1 RAS p21 protein activator (GTPase activating protein) 1 2.254
RICTOR RPTOR independent companion of MTOR, complex 2 2.182
RPS6 ribosomal protein S6 2.132
PMEL premelanosome protein 2.126
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.112
CALD1 caldesmon 1 2.086
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 2.084
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 2.043
MITF microphthalmia-associated transcription factor 2.041
CTSK cathepsin K 1.984
FLT4 fms-related tyrosine kinase 4 1.977
FNIP2 folliculin interacting protein 2 1.976
PGR progesterone receptor 1.951
MAPKAP1 mitogen-activated protein kinase associated protein 1 1.949
ESR1 estrogen receptor 1 1.933
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.913
VEGFC vascular endothelial growth factor C 1.91
AKT1S1 AKT1 substrate 1 (proline-rich) 1.888
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.88
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.872
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.864
FNIP1 folliculin interacting protein 1 1.863
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.809
CD34 CD34 molecule 1.804
DEPTOR DEP domain containing MTOR-interacting protein 1.803
CD1A CD1a molecule 1.773
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.76
CD1E CD1e molecule 1.752
PRR5 proline rich 5 (renal) 1.744
PTEN phosphatase and tensin homolog 1.734
CD1B CD1b molecule 1.726
EIF4E eukaryotic translation initiation factor 4E 1.715
ULK1 unc-51 like autophagy activating kinase 1 1.712
RRAGC Ras-related GTP binding C 1.71
STK11 serine/threonine kinase 11 1.694
MME membrane metallo-endopeptidase 1.682
CD1D CD1d molecule 1.661
CD1C CD1c molecule 1.661
TFEB transcription factor EB 1.648
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 1.637
PECAM1 platelet/endothelial cell adhesion molecule 1 1.631
RRAGB Ras-related GTP binding B 1.629
ELN elastin 1.592
RRAGA Ras-related GTP binding A 1.591
TP53 tumor protein p53 1.563
ANO1 anoctamin 1, calcium activated chloride channel 1.526
TYR tyrosinase 1.526
SLC38A9 solute carrier family 38, member 9 1.508
NF1 neurofibromin 1 1.502
PDPN podoplanin 1.501
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.49
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.48
DDIT4 DNA-damage-inducible transcript 4 1.466
PROX1 prospero homeobox 1 1.462
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.444
RRAGD Ras-related GTP binding D 1.44
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.437
RHEBL1 Ras homolog enriched in brain like 1 1.437
ITFG2 integrin alpha FG-GAP repeat containing 2 1.432
EGF epidermal growth factor 1.431
MMP2 matrix metallopeptidase 2 1.426
FAM161B family with sequence similarity 161, member B 1.419
RHOA ras homolog family member A 1.416
SGK1 serum/glucocorticoid regulated kinase 1 1.41
ALB albumin 1.406
MLANA melan-A 1.405
SYP synaptophysin 1.393
EGFR epidermal growth factor receptor 1.368
SZT2 seizure threshold 2 homolog (mouse) 1.368
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.366
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.364
KRT7 keratin 7, type II 1.358
KDR kinase insert domain receptor 1.356
EIF4A2 eukaryotic translation initiation factor 4A2 1.349
CD68 CD68 molecule 1.346
ATG13 autophagy related 13 1.331
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.327
MUC1 mucin 1, cell surface associated 1.322
MMP9 matrix metallopeptidase 9 1.321
TGFB1 transforming growth factor, beta 1 1.314
NKX2-1 NK2 homeobox 1 1.312
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 1.308
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.292
EIF4B eukaryotic translation initiation factor 4B 1.29
DEPDC5 DEP domain containing 5 1.289
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.281
TFEC transcription factor EC 1.269
INS insulin 1.269
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.266
IGF1 insulin-like growth factor 1 (somatomedin C) 1.26
WDR59 WD repeat domain 59 1.257
SOX10 SRY (sex determining region Y)-box 10 1.257
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.255
TBC1D3F TBC1 domain family, member 3F 1.253
WDR24 WD repeat domain 24 1.246
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 1.24
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.237
EIF4A1 eukaryotic translation initiation factor 4A1 1.235
CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 1.235
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 1.234
PCNA proliferating cell nuclear antigen 1.231
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 1.225
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 1.224
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.223
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.222
CRP C-reactive protein, pentraxin-related 1.219
GPNMB glycoprotein (transmembrane) nmb 1.219
PAX8 paired box 8 1.217
ELOC elongin C 1.217
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.214
EFNA5 ephrin-A5 1.211
IGF1R insulin-like growth factor 1 receptor 1.208
SFTPC surfactant protein C 1.208
IRS1 insulin receptor substrate 1 1.207
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.205
IL6 interleukin 6 1.202
ACTB actin, beta 1.201
KPTN kaptin (actin binding protein) 1.2
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 1.193
RAP1GAP RAP1 GTPase activating protein 1.19
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.186
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.182
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.178
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.177
ENO2 enolase 2 (gamma, neuronal) 1.172
ERBB2 erb-b2 receptor tyrosine kinase 2 1.163
TCHP trichoplein, keratin filament binding 1.156
GRB10 growth factor receptor-bound protein 10 1.151
MMP7 matrix metallopeptidase 7 1.149
MYH10 myosin, heavy chain 10, non-muscle 1.143
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.143
SEH1L SEH1-like (S. cerevisiae) 1.142
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 1.133
UTS2 urotensin 2 1.132
SST somatostatin 1.127
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 1.122
MAPK3 mitogen-activated protein kinase 3 1.115
IFNG interferon, gamma 1.107
EZR ezrin 1.106
CD4 CD4 molecule 1.105
MYH14 myosin, heavy chain 14, non-muscle 1.105
USP6 ubiquitin specific peptidase 6 1.103
CD207 CD207 molecule, langerin 1.101
CD99 CD99 molecule 1.1
CD99L2 CD99 molecule-like 2 1.097
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 1.088
ATG5 autophagy related 5 1.085
MAP2K1 mitogen-activated protein kinase kinase 1 1.075
BECN1 beclin 1, autophagy related 1.073
CD8A CD8a molecule 1.072
EWSR1 EWS RNA-binding protein 1 1.072
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.068
MYOG myogenin (myogenic factor 4) 1.068
IFNA2 interferon, alpha 2 1.066
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) 1.062
CALB2 calbindin 2 1.061
SESN2 sestrin 2 1.057
LARP1B La ribonucleoprotein domain family, member 1B 1.057
SQSTM1 sequestosome 1 1.056
CDC16 cell division cycle 16 1.052
RDX radixin 1.05
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.05
NF2 neurofibromin 2 (merlin) 1.049
CCND1 cyclin D1 1.046
CHGA chromogranin A 1.037
SEC13 SEC13 homolog (S. cerevisiae) 1.036
CDK2 cyclin-dependent kinase 2 1.033
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.03
ALK anaplastic lymphoma receptor tyrosine kinase 1.029
HOXD11 homeobox D11 1.029
UTS2R urotensin 2 receptor 1.021
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.021
RB1CC1 RB1-inducible coiled-coil 1 1.021
PXDN peroxidasin 1.018
TNF tumor necrosis factor 1.016
MSN moesin 1.015
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 1.012
SS18 synovial sarcoma translocation, chromosome 18 1.012
CCL2 chemokine (C-C motif) ligand 2 1.011
PXDNL peroxidasin-like 1.01
SLAMF1 signaling lymphocytic activation molecule family member 1 1.01
PRKCA protein kinase C, alpha 1.007
TTI1 TELO2 interacting protein 1 1.002
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 1.0
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.0