Lymphohistiocytosis, Hemophagocytic Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0024291
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Genes

114 genes associated with the disease Lymphohistiocytosis, Hemophagocytic in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTB actin, beta
ADA adenosine deaminase
ALB albumin
ALK anaplastic lymphoma receptor tyrosine kinase
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APCS amyloid P component, serum
APOL1 apolipoprotein L, 1
ARR3 arrestin 3, retinal (X-arrestin)
ASRGL1 asparaginase like 1
ATF5 activating transcription factor 5
B3GAT1 beta-1,3-glucuronyltransferase 1
BCL3 B-cell CLL/lymphoma 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASR calcium-sensing receptor
CCDC22 coiled-coil domain containing 22
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CD163 CD163 molecule
CD40LG CD40 ligand
CD47 CD47 molecule
CD52 CD52 molecule
CDC42 cell division cycle 42
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CXADR coxsackie virus and adenovirus receptor
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
DNASE1L3 deoxyribonuclease I-like 3
EEA1 early endosome antigen 1
ELP1 elongator acetyltransferase complex subunit 1
FGL1 fibrinogen-like 1
FHL2 four and a half LIM domains 2
FHL3 four and a half LIM domains 3
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GATA2 GATA binding protein 2
GATA4 GATA binding protein 4
GNLY granulysin
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HAVCR2 hepatitis A virus cellular receptor 2
HAX1 HCLS1 associated protein X-1
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HPS1 Hermansky-Pudlak syndrome 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL16 interleukin 16
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL4 interleukin 4
IL6 interleukin 6
IRF5 interferon regulatory factor 5
ISG20 interferon stimulated exonuclease gene 20kDa
ITK IL2-inducible T-cell kinase
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
LAMP1 lysosomal-associated membrane protein 1
LYST lysosomal trafficking regulator
MAGT1 magnesium transporter 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MIP major intrinsic protein of lens fiber
NAAA N-acylethanolamine acid amidase
NCAM1 neural cell adhesion molecule 1
NLRC4 NLR family, CARD domain containing 4
NR1I3 nuclear receptor subfamily 1, group I, member 3
PDLIM7 PDZ and LIM domain 7 (enigma)
PFN1 profilin 1
PRF1 perforin 1 (pore forming protein)
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PROX1 prospero homeobox 1
PTF1A pancreas specific transcription factor, 1a
PTPRC protein tyrosine phosphatase, receptor type, C
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RAB27A RAB27A, member RAS oncogene family
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RC3H1 ring finger and CCCH-type domains 1
RUNX1 runt-related transcription factor 1
SH2D1A SH2 domain containing 1A
SIRPA signal-regulatory protein alpha
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SRSF1 serine/arginine-rich splicing factor 1
SRSF6 serine/arginine-rich splicing factor 6
STX11 syntaxin 11
STXBP2 syntaxin binding protein 2
TCF3 transcription factor 3
TCN2 transcobalamin II
TFF1 trefoil factor 1
THBD thrombomodulin
TLR9 toll-like receptor 9
TMEM201 transmembrane protein 201
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRIM13 tripartite motif containing 13
UNC13D unc-13 homolog D (C. elegans)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase