Lymphoid Leukemia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0023448
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Genes

267 genes associated with the disease Lymphoid Leukemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
A1CF APOBEC1 complementation factor
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AFF4 AF4/FMR2 family, member 4
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
AMPD1 adenosine monophosphate deaminase 1
ANPEP alanyl (membrane) aminopeptidase
ARR3 arrestin 3, retinal (X-arrestin)
ASIP agouti signaling protein
ASPA aspartoacylase
ASPG asparaginase
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATP11A ATPase, class VI, type 11A
AXL AXL receptor tyrosine kinase
B3GAT1 beta-1,3-glucuronyltransferase 1
BAALC brain and acute leukemia, cytoplasmic
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BLNK B-cell linker
BMI1 BMI1 proto-oncogene, polycomb ring finger
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C11ORF65 chromosome 11 open reading frame 65
C3 complement component 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CD19 CD19 molecule
CD22 CD22 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CD58 CD58 molecule
CDK2 cyclin-dependent kinase 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CLPTM1L CLPTM1-like
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CNTNAP1 contactin associated protein 1
COL18A1 collagen, type XVIII, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSG cathepsin G
CTTN cortactin
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DERL1 derlin 1
DLL1 delta-like 1 (Drosophila)
DNTT DNA nucleotidylexotransferase
DOCK8 dedicator of cytokinesis 8
E2F1 E2F transcription factor 1
EBP emopamil binding protein (sterol isomerase)
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4E eukaryotic translation initiation factor 4E
ELP2 elongator acetyltransferase complex subunit 2
ENG endoglin
EPHA1 EPH receptor A1
EPHA3 EPH receptor A3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV6 ets variant 6
EVPL envoplakin
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBXW11 F-box and WD repeat domain containing 11
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FDPS farnesyl diphosphate synthase
FES FES proto-oncogene, tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FLT3 fms-related tyrosine kinase 3
FMN2 formin 2
FOXO3 forkhead box O3
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GCSAM germinal center-associated, signaling and motility
GFER growth factor, augmenter of liver regeneration
GFI1 growth factor independent 1 transcription repressor
GGPS1 geranylgeranyl diphosphate synthase 1
GLIS2 GLIS family zinc finger 2
GML glycosylphosphatidylinositol anchored molecule like
GRB2 growth factor receptor-bound protein 2
GSTK1 glutathione S-transferase kappa 1
HOXC5 homeobox C5
HPGDS hematopoietic prostaglandin D synthase
HPSE heparanase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IFNB1 interferon, beta 1, fibroblast
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
IGH immunoglobulin heavy locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL11 interleukin 11
IL15 interleukin 15
IL16 interleukin 16
IL1B interleukin 1, beta
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL3 interleukin 3
IL3RA interleukin 3 receptor, alpha (low affinity)
IL6 interleukin 6
IPCEF1 interaction protein for cytohesin exchange factors 1
IRX3 iroquois homeobox 3
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
KDM2B lysine (K)-specific demethylase 2B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRT20 keratin 20, type I
KRT7 keratin 7, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LEF1 lymphoid enhancer-binding factor 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK3 mitogen-activated protein kinase 3
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MERTK MER proto-oncogene, tyrosine kinase
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH6 mutS homolog 6
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD1 MAX dimerization protein 1
MYADM myeloid-associated differentiation marker
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOD1 myogenic differentiation 1
NFIL3 nuclear factor, interleukin 3 regulated
NKX3-1 NK3 homeobox 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR2E1 nuclear receptor subfamily 2, group E, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NT5C2 5'-nucleotidase, cytosolic II
NUP98 nucleoporin 98kDa
ODC1 ornithine decarboxylase 1
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
PAX5 paired box 5
PBX1 pre-B-cell leukemia homeobox 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDIK1L PDLIM1 interacting kinase 1 like
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDLIM7 PDZ and LIM domain 7 (enigma)
PGP phosphoglycolate phosphatase
PLAT plasminogen activator, tissue
PLD2 phospholipase D2
POMC proopiomelanocortin
POT1 protection of telomeres 1
PPARA peroxisome proliferator-activated receptor alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRMT5 protein arginine methyltransferase 5
PRTN3 proteinase 3
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRC protein tyrosine phosphatase, receptor type, C
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RAG1 recombination activating gene 1
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RCSD1 RCSD domain containing 1
ROPN1L rhophilin associated tail protein 1-like
RPS14 ribosomal protein S14
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A8 S100 calcium binding protein A8
SCLY selenocysteine lyase
SELPLG selectin P ligand
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH2B3 SH2B adaptor protein 3
SIAH2 siah E3 ubiquitin protein ligase 2
SIRT1 sirtuin 1
SIX6 SIX homeobox 6
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SOX11 SRY (sex determining region Y)-box 11
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPP1 secreted phosphoprotein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase
TAL1 T-cell acute lymphocytic leukemia 1
TARP TCR gamma alternate reading frame protein
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCF3 transcription factor 3
TERT telomerase reverse transcriptase
TFIP11 tuftelin interacting protein 11
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TLX1 T-cell leukemia homeobox 1
TLX3 T-cell leukemia homeobox 3
TMEM132D transmembrane protein 132D
TNF tumor necrosis factor
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TPMT thiopurine S-methyltransferase
TRG T cell receptor gamma locus
TRIM13 tripartite motif containing 13
TRIM33 tripartite motif containing 33
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TYK2 tyrosine kinase 2
UCN urocortin
UHRF1 ubiquitin-like with PHD and ring finger domains 1
VPREB1 pre-B lymphocyte 1
WNT3A wingless-type MMTV integration site family, member 3A
WNT9A wingless-type MMTV integration site family, member 9A
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
YY1 YY1 transcription factor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF384 zinc finger protein 384