Lymphopenia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A leukopenia that is the condition of having an abnormally low level of lymphocytes in the blood. (Human Disease Ontology, DOID_614)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D008231
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Genes

123 genes/proteins associated with the disease Lymphopenia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
IL1B interleukin 1, beta 2.88009
IL7 interleukin 7 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.64775
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.57853
TP53 tumor protein p53 1.50423
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.46542
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.38242
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.35934
RB1 retinoblastoma 1 1.35386
CLU clusterin 1.34926
BCL2 B-cell CLL/lymphoma 2 1.34169
CXCL8 chemokine (C-X-C motif) ligand 8 1.3388
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.33346
TNF tumor necrosis factor 1.33169
INSIG1 insulin induced gene 1 1.30026
IL12B interleukin 12B 1.29502
IL4 interleukin 4 1.2944
VEGFA vascular endothelial growth factor A 1.29011
JUN jun proto-oncogene 1.2898
WEE1 WEE1 G2 checkpoint kinase 1.27845
BCL2L1 BCL2-like 1 1.25214
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.25183
BIRC5 baculoviral IAP repeat containing 5 1.2509
GSTP1 glutathione S-transferase pi 1 1.2437
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.22566
MAP2K1 mitogen-activated protein kinase kinase 1 1.22534
MSMO1 methylsterol monooxygenase 1 1.21759
GSTM1 glutathione S-transferase mu 1 1.21631
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 1.21108
GJA1 gap junction protein, alpha 1, 43kDa 1.20881
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.20719
TPM1 tropomyosin 1 (alpha) 1.19868
SRGN serglycin 1.19672
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.19672
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.19672
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.18293
IL6 interleukin 6 1.18059
CCND1 cyclin D1 1.16302
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.15831
PSAP prosaposin 1.15492
TEK TEK tyrosine kinase, endothelial 1.15256
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 1.15189
CCND3 cyclin D3 1.15055
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 1.15022
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 1.14302
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.13793
ATF5 activating transcription factor 5 1.13793
NFIB nuclear factor I/B 1.13793
CDK1 cyclin-dependent kinase 1 1.13415
F3 coagulation factor III (thromboplastin, tissue factor) 1.13143
CXCR4 chemokine (C-X-C motif) receptor 4 1.13143
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.12805
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.12219
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.12082
AOX1 aldehyde oxidase 1 1.11707
VWF von Willebrand factor 1.10977
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.10699
CCL2 chemokine (C-C motif) ligand 2 1.10631
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.10493
GADD45A growth arrest and DNA-damage-inducible, alpha 1.10282
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.10033
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.09541
ONECUT1 one cut homeobox 1 1.09047
CCNB1 cyclin B1 1.08904
IGFBP3 insulin-like growth factor binding protein 3 1.08797
MT2A metallothionein 2A 1.08797
BIRC3 baculoviral IAP repeat containing 3 1.08442
RBP1 retinol binding protein 1, cellular 1.08231
HADH hydroxyacyl-CoA dehydrogenase 1.08231
SATB1 SATB homeobox 1 1.08055
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.07875
MAPK3 mitogen-activated protein kinase 3 1.07768
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.0766
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.07625
NQO1 NAD(P)H dehydrogenase, quinone 1 1.07128
PCNA proliferating cell nuclear antigen 1.07022
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.06987
MAPK1 mitogen-activated protein kinase 1 1.06952
CDKN2A cyclin-dependent kinase inhibitor 2A 1.06808
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 1.06625
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.06625
CCNG2 cyclin G2 1.06588
CD36 CD36 molecule (thrombospondin receptor) 1.06333
H2AFX H2A histone family, member X 1.06152
SPINT2 serine peptidase inhibitor, Kunitz type, 2 1.06152
PLK2 polo-like kinase 2 1.06152
DIABLO diablo, IAP-binding mitochondrial protein 1.06152
TOP2A topoisomerase (DNA) II alpha 170kDa 1.06116
GSTA5 glutathione S-transferase alpha 5 1.05936
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.059
FGB fibrinogen beta chain 1.05757
ELOVL6 ELOVL fatty acid elongase 6 1.05535
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.04757
VAMP8 vesicle-associated membrane protein 8 1.04501
FXYD3 FXYD domain containing ion transport regulator 3 1.04465
FDPS farnesyl diphosphate synthase 1.04389
BAX BCL2-associated X protein 1.04163
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.03864
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.03641
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.03419
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.03271
PDGFC platelet derived growth factor C 1.03235
FASN fatty acid synthase 1.03122
AQP3 aquaporin 3 (Gill blood group) 1.03084
HSPA1A heat shock 70kDa protein 1A 1.03009
AOC1 amine oxidase, copper containing 1 1.03009
SOD2 superoxide dismutase 2, mitochondrial 1.02971
CTH cystathionine gamma-lyase 1.02933
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.02746
POR P450 (cytochrome) oxidoreductase 1.02596
EGFR epidermal growth factor receptor 1.02559
PFN2 profilin 2 1.02447
SQLE squalene epoxidase 1.0241
IRF1 interferon regulatory factor 1 1.02225
DLC1 DLC1 Rho GTPase activating protein 1.02114
LOX lysyl oxidase 1.0204
GADD45G growth arrest and DNA-damage-inducible, gamma 1.0204
G6PC glucose-6-phosphatase, catalytic subunit 1.0189
PRNP prion protein 1.0189
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.01739
DSP desmoplakin 1.01399
ESR1 estrogen receptor 1 1.01399
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 1.01025