Lysosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. (Gene Ontology, GO_0005764)
External Link http://amigo.geneontology.org/amigo/term/GO:0005764
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Genes

1000 proteins co-occuring with the Lysosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
LAMP1 lysosomal-associated membrane protein 1 3.951
BECN1 beclin 1, autophagy related 3.83
CTSB cathepsin B 3.786
MTOR mechanistic target of rapamycin (serine/threonine kinase) 3.769
CTSS cathepsin S 3.757
CTSD cathepsin D 3.75
ATG5 autophagy related 5 3.748
SQSTM1 sequestosome 1 3.687
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 3.654
TFEB transcription factor EB 3.644
ATG7 autophagy related 7 3.633
LAMP2 lysosomal-associated membrane protein 2 3.63
ULK1 unc-51 like autophagy activating kinase 1 3.596
AKT1 v-akt murine thymoma viral oncogene homolog 1 3.497
IL1B interleukin 1, beta 3.493
ATG12 autophagy related 12 3.477
TNF tumor necrosis factor 3.436
CTSL cathepsin L 3.431
RAB5A RAB5A, member RAS oncogene family 3.43
GABARAPL1 GABA(A) receptor-associated protein like 1 3.414
IL6 interleukin 6 3.408
GABARAPL2 GABA(A) receptor-associated protein-like 2 3.388
IFNG interferon, gamma 3.382
FBF1 Fas (TNFRSF6) binding factor 1 3.381
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 3.354
NPC1 Niemann-Pick disease, type C1 3.351
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3.35
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 3.348
EEA1 early endosome antigen 1 3.34
CD8A CD8a molecule 3.339
DNAH8 dynein, axonemal, heavy chain 8 3.336
CD4 CD4 molecule 3.336
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 3.334
CASP3 caspase 3, apoptosis-related cysteine peptidase 3.332
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.293
TP53 tumor protein p53 3.285
PINK1 PTEN induced putative kinase 1 3.284
MAP1S microtubule-associated protein 1S 3.272
GAPDH glyceraldehyde-3-phosphate dehydrogenase 3.271
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 3.269
BCL2 B-cell CLL/lymphoma 2 3.257
EGFR epidermal growth factor receptor 3.246
GBA1 glucosylceramidase beta 1 3.24
ATG3 autophagy related 3 3.224
TLR4 toll-like receptor 4 3.219
INS insulin 3.214
CASP1 caspase 1, apoptosis-related cysteine peptidase 3.211
APP amyloid beta (A4) precursor protein 3.204
MAP1B microtubule-associated protein 1B 3.194
TGFB1 transforming growth factor, beta 1 3.193
ATG14 autophagy related 14 3.185
ATG13 autophagy related 13 3.184
TFRC transferrin receptor 3.177
RAB11A RAB11A, member RAS oncogene family 3.177
CD63 CD63 molecule 3.167
IL10 interleukin 10 3.166
NPC2 Niemann-Pick disease, type C2 3.157
RB1CC1 RB1-inducible coiled-coil 1 3.157
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 3.153
MCOLN1 mucolipin 1 3.148
OGA O-GlcNAcase 3.139
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 3.136
PRKN parkin RBR E3 ubiquitin protein ligase 3.122
HSPA8 heat shock 70kDa protein 8 3.118
IL18 interleukin 18 3.109
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 3.1
APOE apolipoprotein E 3.093
PXDNL peroxidasin-like 3.088
EGF epidermal growth factor 3.086
TLR9 toll-like receptor 9 3.084
GABARAP GABA(A) receptor-associated protein 3.075
ANXA5 annexin A5 3.057
RHEB Ras homolog enriched in brain 3.052
TLR2 toll-like receptor 2 3.05
HSPA4 heat shock 70kDa protein 4 3.049
CYCS cytochrome c, somatic 3.043
CD68 CD68 molecule 3.041
GLB1 galactosidase, beta 1 3.035
IGF2R insulin-like growth factor 2 receptor 3.033
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 3.031
ERBB2 erb-b2 receptor tyrosine kinase 2 3.025
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 3.025
IL1A interleukin 1, alpha 3.019
CCL2 chemokine (C-C motif) ligand 2 3.018
IDUA iduronidase, alpha-L- 3.014
SCARB2 scavenger receptor class B, member 2 3.013
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 3.013
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 3.012
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 3.012
UVRAG UV radiation resistance associated 3.003
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.995
RPTOR regulatory associated protein of MTOR, complex 1 2.993
CXCL8 chemokine (C-X-C motif) ligand 8 2.989
CALCOCO2 calcium binding and coiled-coil domain 2 2.987
TLR7 toll-like receptor 7 2.987
ZNF395 zinc finger protein 395 2.985
IL2 interleukin 2 2.984
NBR1 neighbor of BRCA1 gene 1 2.982
IL4 interleukin 4 2.98
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 2.98
STX17 syntaxin 17 2.98
SCGB1D1 secretoglobin, family 1D, member 1 2.979
MGAM maltase-glucoamylase 2.966
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 2.965
CD300C CD300c molecule 2.962
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.96
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.96
BAX BCL2-associated X protein 2.951
SIRT1 sirtuin 1 2.948
TLR3 toll-like receptor 3 2.943
MYD88 myeloid differentiation primary response 88 2.942
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 2.939
CD274 CD274 molecule 2.938
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.937
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.929
ATP13A2 ATPase type 13A2 2.929
PTEN phosphatase and tensin homolog 2.926
IFNB1 interferon, beta 1, fibroblast 2.924
SCARB1 scavenger receptor class B, member 1 2.924
LRRK2 leucine-rich repeat kinase 2 2.919
RAB7A RAB7A, member RAS oncogene family 2.916
ATG4B autophagy related 4B, cysteine peptidase 2.916
OPTN optineurin 2.909
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.908
PPT1 palmitoyl-protein thioesterase 1 2.905
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.905
CD44 CD44 molecule (Indian blood group) 2.905
TSC2 tuberous sclerosis 2 2.904
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.903
ATG10 autophagy related 10 2.902
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.901
MAPK3 mitogen-activated protein kinase 3 2.901
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 2.898
ATG101 autophagy related 101 2.893
CD86 CD86 molecule 2.891
CTSK cathepsin K 2.89
ACE2 angiotensin I converting enzyme 2 2.89
PCSK9 proprotein convertase subtilisin/kexin type 9 2.878
IGF1 insulin-like growth factor 1 (somatomedin C) 2.876
IFNA1 interferon, alpha 1 2.876
FOXO3 forkhead box O3 2.874
TFE3 transcription factor binding to IGHM enhancer 3 2.869
JUN jun proto-oncogene 2.867
GUSB glucuronidase, beta 2.867
CTSC cathepsin C 2.866
MMP9 matrix metallopeptidase 9 2.865
TSG101 tumor susceptibility 101 2.848
CTSA cathepsin A 2.846
VAMP8 vesicle-associated membrane protein 8 2.844
FN1 fibronectin 1 2.838
BCL2L1 BCL2-like 1 2.837
CANX calnexin 2.836
RAB27A RAB27A, member RAS oncogene family 2.835
TBK1 TANK-binding kinase 1 2.833
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.833
CLN3 ceroid-lipofuscinosis, neuronal 3 2.83
MPO myeloperoxidase 2.83
BACE1 beta-site APP-cleaving enzyme 1 2.83
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.829
RRAGC Ras-related GTP binding C 2.823
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.818
AMBRA1 autophagy/beclin-1 regulator 1 2.816
CD80 CD80 molecule 2.815
GSK3B glycogen synthase kinase 3 beta 2.813
TARDBP TAR DNA binding protein 2.812
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 2.808
TPCN2 two pore segment channel 2 2.807
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.807
RIGI RNA sensor RIG-I 2.803
MAPT microtubule-associated protein tau 2.8
CTSG cathepsin G 2.799
CD36 CD36 molecule (thrombospondin receptor) 2.799
LGMN legumain 2.797
RAB4A RAB4A, member RAS oncogene family 2.796
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2.795
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.792
RRAGA Ras-related GTP binding A 2.791
IRF3 interferon regulatory factor 3 2.789
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.784
AIF1 allograft inflammatory factor 1 2.784
CAV1 caveolin 1, caveolae protein, 22kDa 2.782
PTPRC protein tyrosine phosphatase, receptor type, C 2.779
ICAM1 intercellular adhesion molecule 1 2.775
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 2.772
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.771
TREM2 triggering receptor expressed on myeloid cells 2 2.771
RUBCN rubicon autophagy regulator 2.767
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 2.766
HMGB1 high mobility group box 1 2.765
SORT1 sortilin 1 2.765
VAMP7 vesicle-associated membrane protein 7 2.764
MFN2 mitofusin 2 2.763
PARP1 poly (ADP-ribose) polymerase 1 2.762
NCOA4 nuclear receptor coactivator 4 2.761
SNAP29 synaptosomal-associated protein, 29kDa 2.761
CD40 CD40 molecule, TNF receptor superfamily member 5 2.761
ELANE elastase, neutrophil expressed 2.76
CALR calreticulin 2.759
FURIN furin (paired basic amino acid cleaving enzyme) 2.758
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B 2.756
GSDMD gasdermin D 2.755
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 2.754
CD9 CD9 molecule 2.753
HMOX1 heme oxygenase 1 2.752
PPARG peroxisome proliferator-activated receptor gamma 2.746
STAT1 signal transducer and activator of transcription 1, 91kDa 2.744
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 2.743
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.74
ARSA arylsulfatase A 2.738
NFE2L2 nuclear factor, erythroid 2-like 2 2.736
CD81 CD81 molecule 2.735
FOXO1 forkhead box O1 2.733
PSEN1 presenilin 1 2.729
CCL5 chemokine (C-C motif) ligand 5 2.729
CXCR4 chemokine (C-X-C motif) receptor 4 2.727
PARK7 parkinson protein 7 2.727
CTNS cystinosin, lysosomal cystine transporter 2.725
CGAS cyclic GMP-AMP synthase 2.725
GALNS galactosamine (N-acetyl)-6-sulfatase 2.723
CYBB cytochrome b-245, beta polypeptide 2.719
FBXO32 F-box protein 32 2.717
LTF lactotransferrin 2.717
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.716
FASLG Fas ligand (TNF superfamily, member 6) 2.716
SLC38A9 solute carrier family 38, member 9 2.714
IDS iduronate 2-sulfatase 2.714
GALC galactosylceramidase 2.711
LRP2 low density lipoprotein receptor-related protein 2 2.71
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.71
SOD1 superoxide dismutase 1, soluble 2.708
DNM1L dynamin 1-like 2.708
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.706
SGSH N-sulfoglucosamine sulfohydrolase 2.703
ERVW-1 endogenous retrovirus group W, member 1 2.702
TMPRSS2 transmembrane protease, serine 2 2.701
TLR8 toll-like receptor 8 2.699
AIM2 absent in melanoma 2 2.699
IL13 interleukin 13 2.697
MRC1 mannose receptor, C type 1 2.694
CTSZ cathepsin Z 2.691
ULK2 unc-51 like autophagy activating kinase 2 2.691
STK11 serine/threonine kinase 11 2.691
TYRP1 tyrosinase-related protein 1 2.69
RRAGB Ras-related GTP binding B 2.689
CCL3 chemokine (C-C motif) ligand 3 2.688
GRN granulin 2.686
KEAP1 kelch-like ECH-associated protein 1 2.684
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 2.684
GPX4 glutathione peroxidase 4 2.681
NAGLU N-acetylglucosaminidase, alpha 2.68
FUNDC1 FUN14 domain containing 1 2.679
BDNF brain-derived neurotrophic factor 2.679
CSF1 colony stimulating factor 1 (macrophage) 2.677
CLCN7 chloride channel, voltage-sensitive 7 2.676
HDAC6 histone deacetylase 6 2.674
CDKN2A cyclin-dependent kinase inhibitor 2A 2.674
UGCG UDP-glucose ceramide glucosyltransferase 2.67
CTSH cathepsin H 2.666
RRAGD Ras-related GTP binding D 2.662
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.659
RAB10 RAB10, member RAS oncogene family 2.659
ESR1 estrogen receptor 1 2.652
TGOLN2 trans-golgi network protein 2 2.65
VDAC1 voltage-dependent anion channel 1 2.648
INSR insulin receptor 2.635
NOD2 nucleotide-binding oligomerization domain containing 2 2.633
VCP valosin containing protein 2.629
RAB8A RAB8A, member RAS oncogene family 2.628
C1D C1D nuclear receptor corepressor 2.628
CTRL chymotrypsin-like 2.625
FTH1 ferritin, heavy polypeptide 1 2.623
FOXP3 forkhead box P3 2.62
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.62
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.616
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.615
ARF6 ADP-ribosylation factor 6 2.612
CCND1 cyclin D1 2.612
MMP2 matrix metallopeptidase 2 2.608
ATG9A autophagy related 9A 2.607
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.607
ATF6 activating transcription factor 6 2.606
CLEC7A C-type lectin domain family 7, member A 2.604
NLRC4 NLR family, CARD domain containing 4 2.602
DRAM1 DNA-damage regulated autophagy modulator 1 2.602
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2.602
TMEM106B transmembrane protein 106B 2.597
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.596
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 2.596
MYH14 myosin, heavy chain 14, non-muscle 2.596
ANKRD44 ankyrin repeat domain 44 2.595
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.594
MCL1 myeloid cell leukemia 1 2.593
APOB apolipoprotein B 2.593
GFAP glial fibrillary acidic protein 2.593
MAPK8 mitogen-activated protein kinase 8 2.592
AGFG1 ArfGAP with FG repeats 1 2.592
ERN1 endoplasmic reticulum to nucleus signaling 1 2.591
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.59
CALM3 calmodulin 3 (phosphorylase kinase, delta) 2.589
RIPK3 receptor-interacting serine-threonine kinase 3 2.588
LYST lysosomal trafficking regulator 2.587
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.587
RHOA ras homolog family member A 2.586
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.586
CD209 CD209 molecule 2.586
SYK spleen tyrosine kinase 2.586
PRTN3 proteinase 3 2.585
XBP1 X-box binding protein 1 2.585
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 2.585
GOLGA2 golgin A2 2.585
M6PR mannose-6-phosphate receptor (cation dependent) 2.584
ERV3-1 endogenous retrovirus group 3, member 1 2.584
MLKL mixed lineage kinase domain-like 2.583
IRF7 interferon regulatory factor 7 2.583
IGF1R insulin-like growth factor 1 receptor 2.582
IFI30 interferon, gamma-inducible protein 30 2.581
BECN2 beclin 2 2.581
MAVS mitochondrial antiviral signaling protein 2.581
PPARA peroxisome proliferator-activated receptor alpha 2.581
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.58
CDC42 cell division cycle 42 2.58
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 2.58
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 2.574
CD28 CD28 molecule 2.572
CXCL12 chemokine (C-X-C motif) ligand 12 2.572
RAB35 RAB35, member RAS oncogene family 2.572
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 2.569
LAPTM4B lysosomal protein transmembrane 4 beta 2.567
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 2.567
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.567
CD47 CD47 molecule 2.565
RABIF RAB interacting factor 2.564
IRGM immunity-related GTPase family, M 2.562
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.562
GAA glucosidase, alpha; acid 2.561
CALML3 calmodulin-like 3 2.56
CALML5 calmodulin-like 5 2.56
CREB1 cAMP responsive element binding protein 1 2.56
TLR1 toll-like receptor 1 2.56
GPX3 glutathione peroxidase 3 2.559
MFN1 mitofusin 1 2.558
CLN5 ceroid-lipofuscinosis, neuronal 5 2.558
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 2.558
CALML6 calmodulin-like 6 2.557
CALML4 calmodulin-like 4 2.557
CD19 CD19 molecule 2.557
PRKACB protein kinase, cAMP-dependent, catalytic, beta 2.554
GPX2 glutathione peroxidase 2 2.55
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 2.548
HAMP hepcidin antimicrobial peptide 2.545
ATM ATM serine/threonine kinase 2.545
SLCO6A1 solute carrier organic anion transporter family, member 6A1 2.544
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.543
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.542
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 2.542
NGF nerve growth factor (beta polypeptide) 2.541
SREBF2 sterol regulatory element binding transcription factor 2 2.541
GPX7 glutathione peroxidase 7 2.541
USP8 ubiquitin specific peptidase 8 2.541
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 2.54
GPX8 glutathione peroxidase 8 (putative) 2.54
CSF3 colony stimulating factor 3 (granulocyte) 2.539
ARF1 ADP-ribosylation factor 1 2.538
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.538
CD163 CD163 molecule 2.537
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.536
MITF microphthalmia-associated transcription factor 2.536
GPX5 glutathione peroxidase 5 2.536
CCR2 chemokine (C-C motif) receptor 2 2.535
GPX6 glutathione peroxidase 6 2.535
MT1E metallothionein 1E 2.534
MAN2B1 mannosidase, alpha, class 2B, member 1 2.534
SNX1 sorting nexin 1 2.533
KLRK1 killer cell lectin-like receptor subfamily K, member 1 2.531
FLCN folliculin 2.529
ARRB1 arrestin, beta 1 2.529
MCOLN3 mucolipin 3 2.529
CCL4 chemokine (C-C motif) ligand 4 2.527
CSF1R colony stimulating factor 1 receptor 2.525
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 2.525
BCL2L11 BCL2-like 11 (apoptosis facilitator) 2.523
C3 complement component 3 2.523
ZUP1 zinc finger containing ubiquitin peptidase 1 2.523
JAK2 Janus kinase 2 2.52
CDPF1 cysteine-rich, DPF motif domain containing 1 2.518
RICTOR RPTOR independent companion of MTOR, complex 2 2.518
GCG glucagon 2.518
CTSF cathepsin F 2.516
SESN2 sestrin 2 2.514
ACE angiotensin I converting enzyme 2.513
ARRB2 arrestin, beta 2 2.512
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.511
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.51
TPCN1 two pore segment channel 1 2.508
PKM pyruvate kinase, muscle 2.507
ARL8B ADP-ribosylation factor-like 8B 2.507
ZFYVE1 zinc finger, FYVE domain containing 1 2.506
IGF2 insulin-like growth factor 2 2.504
IFIH1 interferon induced with helicase C domain 1 2.503
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 2.503
CST3 cystatin C 2.503
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 2.502
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 2.5
VCAM1 vascular cell adhesion molecule 1 2.499
CD1D CD1d molecule 2.499
CHMP2B charged multivesicular body protein 2B 2.498
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.498
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.494
IL15 interleukin 15 2.492
B2M beta-2-microglobulin 2.492
PDCD1 programmed cell death 1 2.492
BIRC5 baculoviral IAP repeat containing 5 2.49
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.49
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 2.488
CD34 CD34 molecule 2.487
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 2.487
TMEM175 transmembrane protein 175 2.487
CD40LG CD40 ligand 2.487
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 2.486
ATG4A autophagy related 4A, cysteine peptidase 2.484
TLR5 toll-like receptor 5 2.484
SREBF1 sterol regulatory element binding transcription factor 1 2.483
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.483
CLTC clathrin, heavy chain (Hc) 2.483
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 2.48
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 2.479
CHIT1 chitinase 1 (chitotriosidase) 2.476
NLRP1 NLR family, pyrin domain containing 1 2.476
EFNA5 ephrin-A5 2.474
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.471
APOA1 apolipoprotein A-I 2.471
CLU clusterin 2.471
IL5 interleukin 5 2.471
LCN2 lipocalin 2 2.469
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2.468
PECAM1 platelet/endothelial cell adhesion molecule 1 2.468
ATG4D autophagy related 4D, cysteine peptidase 2.466
DEPTOR DEP domain containing MTOR-interacting protein 2.466
SPHK1 sphingosine kinase 1 2.465
HDAC9 histone deacetylase 9 2.464
GM2A GM2 ganglioside activator 2.464
RAB29 RAB29, member RAS oncogene family 2.462
PYCARD PYD and CARD domain containing 2.462
IRS1 insulin receptor substrate 1 2.461
DNM2 dynamin 2 2.461
FUCA1 fucosidase, alpha-L- 1, tissue 2.46
IDO1 indoleamine 2,3-dioxygenase 1 2.46
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.459
SNAP23 synaptosomal-associated protein, 23kDa 2.459
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 2.458
SLTM SAFB-like, transcription modulator 2.454
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 2.454
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.453
LEP leptin 2.453
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.453
SYT7 synaptotagmin VII 2.452
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.452
BAG3 BCL2-associated athanogene 3 2.451
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.451
GBA2 glucosidase, beta (bile acid) 2 2.45
HSPB3 heat shock 27kDa protein 3 2.448
AKT1S1 AKT1 substrate 1 (proline-rich) 2.448
UNC93B1 unc-93 homolog B1 (C. elegans) 2.446
LGALS8 lectin, galactoside-binding, soluble, 8 2.446
KDR kinase insert domain receptor 2.445
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 2.444
PLEK pleckstrin 2.443
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.442
IL1R1 interleukin 1 receptor, type I 2.442
SIRT3 sirtuin 3 2.441
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.44
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.44
RAB27B RAB27B, member RAS oncogene family 2.439
RAB32 RAB32, member RAS oncogene family 2.438
AXL AXL receptor tyrosine kinase 2.437
MCOLN2 mucolipin 2 2.437
ADAM10 ADAM metallopeptidase domain 10 2.436
MAPK1 mitogen-activated protein kinase 1 2.436
IFITM3 interferon induced transmembrane protein 3 2.436
TXNIP thioredoxin interacting protein 2.435
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.433
PLEK2 pleckstrin 2 2.433
NCAM1 neural cell adhesion molecule 1 2.432
CDK4 cyclin-dependent kinase 4 2.432
ATG4C autophagy related 4C, cysteine peptidase 2.43
CD276 CD276 molecule 2.427
APAF1 apoptotic peptidase activating factor 1 2.426
COX4I1 cytochrome c oxidase subunit IV isoform 1 2.426
PNPLA2 patatin-like phospholipase domain containing 2 2.426
DPP4 dipeptidyl-peptidase 4 2.426
CUBN cubilin (intrinsic factor-cobalamin receptor) 2.425
BST2 bone marrow stromal cell antigen 2 2.425
RAB1A RAB1A, member RAS oncogene family 2.424
CD38 CD38 molecule 2.423
TLR6 toll-like receptor 6 2.423
FOLR2 folate receptor 2 (fetal) 2.421
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.421
CD33 CD33 molecule 2.42
ANXA2 annexin A2 2.419
TYROBP TYRO protein tyrosine kinase binding protein 2.419
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.418
ERLN endoregulin 2.418
RETREG1 reticulophagy regulator 1 2.417
CTSE cathepsin E 2.416
FADD Fas (TNFRSF6)-associated via death domain 2.415
TFAM transcription factor A, mitochondrial 2.415
STX7 syntaxin 7 2.415
PLIN2 perilipin 2 2.415
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 2.412
ARL5B ADP-ribosylation factor-like 5B 2.412
CLTCL1 clathrin, heavy chain-like 1 2.411
CTRB1 chymotrypsinogen B1 2.41
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.41
ESX1 ESX homeobox 1 2.41
CXXC1 CXXC finger protein 1 2.41
ASGR1 asialoglycoprotein receptor 1 2.409
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.409
CCR7 chemokine (C-C motif) receptor 7 2.409
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 2.408
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.408
OSBP oxysterol binding protein 2.408
ATF4 activating transcription factor 4 2.407
PSEN2 presenilin 2 2.406
VAMP3 vesicle-associated membrane protein 3 2.406
ISG15 ISG15 ubiquitin-like modifier 2.406
EPS15 epidermal growth factor receptor pathway substrate 15 2.405
CTRB2 chymotrypsinogen B2 2.405
NOD1 nucleotide-binding oligomerization domain containing 1 2.402
FGF7 fibroblast growth factor 7 2.401
IL3 interleukin 3 2.401
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 2.4
VTI1B vesicle transport through interaction with t-SNAREs 1B 2.399
TYR tyrosinase 2.396
HSPB1 heat shock 27kDa protein 1 2.396
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit 2.396
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 2.396
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.395
PLG plasminogen 2.395
IL33 interleukin 33 2.393
LGALS4 lectin, galactoside-binding, soluble, 4 2.392
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.392
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 2.391
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.391
RPS6 ribosomal protein S6 2.391
JAK1 Janus kinase 1 2.388
H3C13 H3 clustered histone 13 2.388
H3-5 H3.5 histone 2.386
H3-4 H3.4 histone, cluster member 2.386
H3-7 H3.7 histone (putative) 2.386
TJP1 tight junction protein 1 2.385
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 2.384
EIF4E eukaryotic translation initiation factor 4E 2.384
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.38
ADAM17 ADAM metallopeptidase domain 17 2.38
DNTT DNA nucleotidylexotransferase 2.38
FUS FUS RNA binding protein 2.38
HLA-DMA major histocompatibility complex, class II, DM alpha 2.38
MERTK MER proto-oncogene, tyrosine kinase 2.379
TH tyrosine hydroxylase 2.377
FOS FBJ murine osteosarcoma viral oncogene homolog 2.377
CD69 CD69 molecule 2.377
IDE insulin-degrading enzyme 2.377
STX6 syntaxin 6 2.376
LAMP3 lysosomal-associated membrane protein 3 2.374
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 2.373
FOLR3 folate receptor 3 (gamma) 2.373
AGER advanced glycosylation end product-specific receptor 2.371
TRAF3 TNF receptor-associated factor 3 2.371
DDIT3 DNA-damage-inducible transcript 3 2.37
SOD2 superoxide dismutase 2, mitochondrial 2.37
FTL ferritin, light polypeptide 2.366
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.366
SUMF1 sulfatase modifying factor 1 2.364
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 2.363
ERBB3 erb-b2 receptor tyrosine kinase 3 2.363
TFEC transcription factor EC 2.363
FGF10 fibroblast growth factor 10 2.362
PI3 peptidase inhibitor 3, skin-derived 2.361
IRAK1 interleukin-1 receptor-associated kinase 1 2.361
GRB2 growth factor receptor-bound protein 2 2.36
CIDEB cell death-inducing DFFA-like effector b 2.36
VWF von Willebrand factor 2.359
NOTCH1 notch 1 2.358
TCHP trichoplein, keratin filament binding 2.358
RAB6A RAB6A, member RAS oncogene family 2.356
TBC1D15 TBC1 domain family, member 15 2.356
POTEF POTE ankyrin domain family, member F 2.356
ACP5 acid phosphatase 5, tartrate resistant 2.356
SELL selectin L 2.356
MAN2C1 mannosidase, alpha, class 2C, member 1 2.355
FGF8 fibroblast growth factor 8 (androgen-induced) 2.354
LOX lysyl oxidase 2.354
IZUMO1R IZUMO1 receptor, JUNO 2.353
FGF4 fibroblast growth factor 4 2.353
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.352
NQO1 NAD(P)H dehydrogenase, quinone 1 2.352
MAP2K1 mitogen-activated protein kinase kinase 1 2.351
MUC1 mucin 1, cell surface associated 2.351
FGF18 fibroblast growth factor 18 2.35
SDCBP syndecan binding protein (syntenin) 2.35
ADRB2 adrenoceptor beta 2, surface 2.349
FGF9 fibroblast growth factor 9 2.348
PMEL premelanosome protein 2.347
FGF20 fibroblast growth factor 20 2.347
FYN FYN proto-oncogene, Src family tyrosine kinase 2.347
FGF5 fibroblast growth factor 5 2.346
CXCL9 chemokine (C-X-C motif) ligand 9 2.346
CMA1 chymase 1, mast cell 2.345
RAB2A RAB2A, member RAS oncogene family 2.344
MFF mitochondrial fission factor 2.343
SMAD2 SMAD family member 2 2.342
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.342
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 2.342
FGF17 fibroblast growth factor 17 2.341
FGF16 fibroblast growth factor 16 2.341
FGF6 fibroblast growth factor 6 2.341
LAPTM5 lysosomal protein transmembrane 5 2.341
SOX2 SRY (sex determining region Y)-box 2 2.34
IL22 interleukin 22 2.339
ATP7A ATPase, Cu++ transporting, alpha polypeptide 2.338
TMEM192 transmembrane protein 192 2.338
CUL3 cullin 3 2.337
PDGFRB platelet-derived growth factor receptor, beta polypeptide 2.336
FGF3 fibroblast growth factor 3 2.336
FGF22 fibroblast growth factor 22 2.336
MFSD8 major facilitator superfamily domain containing 8 2.336
HAVCR2 hepatitis A virus cellular receptor 2 2.335
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.334
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 2.334
CDK5 cyclin-dependent kinase 5 2.332
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.331
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 2.33
ACSL4 acyl-CoA synthetase long-chain family member 4 2.33
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 2.329
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.328
SDC1 syndecan 1 2.327
FLOT1 flotillin 1 2.325
PLA2G15 phospholipase A2, group XV 2.325
IRF1 interferon regulatory factor 1 2.325
CDK2 cyclin-dependent kinase 2 2.325
CAPN1 calpain 1, (mu/I) large subunit 2.325
SIRPA signal-regulatory protein alpha 2.324
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 2.324
KNG1 kininogen 1 2.324
BRCA1 breast cancer 1, early onset 2.323
MMP3 matrix metallopeptidase 3 2.322
ADIPOQ adiponectin, C1Q and collagen domain containing 2.322
A2M alpha-2-macroglobulin 2.322
LAP3 leucine aminopeptidase 3 2.322
UBQLN2 ubiquilin 2 2.321
EPAS1 endothelial PAS domain protein 1 2.321
IL7 interleukin 7 2.321
SNAI1 snail family zinc finger 1 2.32
SNX27 sorting nexin family member 27 2.32
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 2.32
PTK2 protein tyrosine kinase 2 2.318
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.318
LMNB1 lamin B1 2.317
DNASE2 deoxyribonuclease II, lysosomal 2.316
POMC proopiomelanocortin 2.316
BIN1 bridging integrator 1 2.315
STEAP3 STEAP family member 3, metalloreductase 2.315
LY75-CD302 LY75-CD302 readthrough 2.315
GNLY granulysin 2.314
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 2.313
DIABLO diablo, IAP-binding mitochondrial protein 2.313
SPI1 Spi-1 proto-oncogene 2.313
MSTN myostatin 2.312
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.312
GOLGB1 golgin B1 2.31
BSG basigin (Ok blood group) 2.31
FIG4 FIG4 phosphoinositide 5-phosphatase 2.31
DDIT4 DNA-damage-inducible transcript 4 2.309
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.309
SPHK2 sphingosine kinase 2 2.309
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 2.309
STX4 syntaxin 4 2.306
ATG2A autophagy related 2A 2.306
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.305
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 2.305
ANXA1 annexin A1 2.305
CHUK conserved helix-loop-helix ubiquitous kinase 2.305
WDR45 WD repeat domain 45 2.304
HSPA1B heat shock 70kDa protein 1B 2.303
APOL1 apolipoprotein L, 1 2.303
CFLAR CASP8 and FADD-like apoptosis regulator 2.303
UNC13D unc-13 homolog D (C. elegans) 2.303
SELE selectin E 2.303
CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 2.303
CXCR2 chemokine (C-X-C motif) receptor 2 2.302
CD1C CD1c molecule 2.302
SMAD3 SMAD family member 3 2.301
GJA1 gap junction protein, alpha 1, 43kDa 2.299
MMEL1 membrane metallo-endopeptidase-like 1 2.298
ATG9B autophagy related 9B 2.295
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 2.294
LDHA lactate dehydrogenase A 2.294
LCK LCK proto-oncogene, Src family tyrosine kinase 2.293
NEU4 sialidase 4 2.293
PROM1 prominin 1 2.293
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 2.292
XPR1 xenotropic and polytropic retrovirus receptor 1 2.292
DAPK1 death-associated protein kinase 1 2.291
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 2.29
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 2.289
HSPB2 heat shock 27kDa protein 2 2.289
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.289
ANPEP alanyl (membrane) aminopeptidase 2.289
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 2.288
PDCD6IP programmed cell death 6 interacting protein 2.288
LAG3 lymphocyte-activation gene 3 2.287
CD83 CD83 molecule 2.286
CD82 CD82 molecule 2.286
GSR glutathione reductase 2.286
TIMP1 TIMP metallopeptidase inhibitor 1 2.285
TMEM119 transmembrane protein 119 2.285
PRKCA protein kinase C, alpha 2.283
THY1 Thy-1 cell surface antigen 2.282
DPP7 dipeptidyl-peptidase 7 2.282
PCNA proliferating cell nuclear antigen 2.281
STAT5A signal transducer and activator of transcription 5A 2.281
NOX4 NADPH oxidase 4 2.281
IREB2 iron-responsive element binding protein 2 2.281
RAB7B RAB7B, member RAS oncogene family 2.281
TRAT1 T cell receptor associated transmembrane adaptor 1 2.28
NANOS3 nanos homolog 3 (Drosophila) 2.28
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2.28
NCR1 natural cytotoxicity triggering receptor 1 2.279
PARL presenilin associated, rhomboid-like 2.278
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.278
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 2.278
STAT5B signal transducer and activator of transcription 5B 2.277
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 2.277
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2.277
SOCS3 suppressor of cytokine signaling 3 2.277
SNAPIN SNAP-associated protein 2.277
NRP1 neuropilin 1 2.276
EDN1 endothelin 1 2.276
EPCAM epithelial cell adhesion molecule 2.274
FASN fatty acid synthase 2.274
CDK1 cyclin-dependent kinase 1 2.274
CAPN2 calpain 2, (m/II) large subunit 2.274
FUCA2 fucosidase, alpha-L- 2, plasma 2.272
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.269
DICER1 dicer 1, ribonuclease type III 2.269
SGK1 serum/glucocorticoid regulated kinase 1 2.269
RAB38 RAB38, member RAS oncogene family 2.269
LYN LYN proto-oncogene, Src family tyrosine kinase 2.268
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 2.268
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 2.268
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 2.267
ARG2 arginase 2 2.263
CXCL2 chemokine (C-X-C motif) ligand 2 2.263
PICALM phosphatidylinositol binding clathrin assembly protein 2.262
SLC66A1 solute carrier family 66 member 1 2.262
STIM1 stromal interaction molecule 1 2.261
PLAU plasminogen activator, urokinase 2.261
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.26
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.26
NAGA N-acetylgalactosaminidase, alpha- 2.259
OSTM1 osteopetrosis associated transmembrane protein 1 2.257
BCR breakpoint cluster region 2.257
TBC1D7 TBC1 domain family, member 7 2.257
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.256
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.256
MAPK14 mitogen-activated protein kinase 14 2.255
ATG2B autophagy related 2B 2.255
VMP1 vacuole membrane protein 1 2.253
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.253
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.252
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.251
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2.251
CXCR3 chemokine (C-X-C motif) receptor 3 2.25
LMLN leishmanolysin-like (metallopeptidase M8 family) 2.25
KLF4 Kruppel-like factor 4 (gut) 2.249
PANX1 pannexin 1 2.249
AXIN1 axin 1 2.248
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) 2.248
SHH sonic hedgehog 2.247
BTK Bruton agammaglobulinemia tyrosine kinase 2.247
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.246
TIMD4 T-cell immunoglobulin and mucin domain containing 4 2.246
F3 coagulation factor III (thromboplastin, tissue factor) 2.246
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 2.244
SPG11 spastic paraplegia 11 (autosomal recessive) 2.244
TGFA transforming growth factor, alpha 2.243
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.243
WDFY3 WD repeat and FYVE domain containing 3 2.243
RUNX2 runt-related transcription factor 2 2.243
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.241
HLA-A major histocompatibility complex, class I, A 2.24
CST7 cystatin F (leukocystatin) 2.24
SNX2 sorting nexin 2 2.24
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 2.24
MAPKAP1 mitogen-activated protein kinase associated protein 1 2.24
PLIN1 perilipin 1 2.239
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.239
SYP synaptophysin 2.238
TOLLIP toll interacting protein 2.238
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.236
PLIN3 perilipin 3 2.235
SIRT2 sirtuin 2 2.232
HPS4 Hermansky-Pudlak syndrome 4 2.232
UBE3A ubiquitin protein ligase E3A 2.228
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.226
SMAD4 SMAD family member 4 2.226
PTPN11 protein tyrosine phosphatase, non-receptor type 11 2.225
HRAS Harvey rat sarcoma viral oncogene homolog 2.225
NEK7 NIMA-related kinase 7 2.224
KCTD7 potassium channel tetramerization domain containing 7 2.224
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.224
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 2.223
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.223
THBS1 thrombospondin 1 2.223
MMP1 matrix metallopeptidase 1 2.222
LPL lipoprotein lipase 2.222
HSPA9 heat shock 70kDa protein 9 (mortalin) 2.221
FKBP1A FK506 binding protein 1A, 12kDa 2.22
MEFV Mediterranean fever 2.22
WAS Wiskott-Aldrich syndrome 2.22
CD22 CD22 molecule 2.219
ATXN3 ataxin 3 2.218
POU5F1 POU class 5 homeobox 1 2.217
GSDMA gasdermin A 2.216
SNX5 sorting nexin 5 2.216
RAB14 RAB14, member RAS oncogene family 2.216
CTTN cortactin 2.215
IDO2 indoleamine 2,3-dioxygenase 2 2.215
MSR1 macrophage scavenger receptor 1 2.214
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.214
NT5E 5'-nucleotidase, ecto (CD73) 2.214
EP300 E1A binding protein p300 2.214
CKM creatine kinase, muscle 2.214
FLT3 fms-related tyrosine kinase 3 2.213
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 2.212
GOLGA1 golgin A1 2.212
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 2.211
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.211
LY96 lymphocyte antigen 96 2.21
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 2.21
CCNL2 cyclin L2 2.21
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2.209
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2.209
CP ceruloplasmin (ferroxidase) 2.209
STAMBP STAM binding protein 2.208
CHMP2A charged multivesicular body protein 2A 2.207
ITCH itchy E3 ubiquitin protein ligase 2.206
TRIM21 tripartite motif containing 21 2.206
CST4 cystatin S 2.205
UBE2S ubiquitin-conjugating enzyme E2S 2.205
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.205
PF4 platelet factor 4 2.203
CD1B CD1b molecule 2.202
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 2.201
SNX17 sorting nexin 17 2.201
TRIM16 tripartite motif containing 16 2.201
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.201
CKB creatine kinase, brain 2.201
OCLN occludin 2.201
DCTN1 dynactin 1 2.2
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.2
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.198
HYAL2 hyaluronoglucosaminidase 2 2.198
SOCS1 suppressor of cytokine signaling 1 2.198
SYNJ1 synaptojanin 1 2.197
CD24 CD24 molecule 2.196
STX8 syntaxin 8 2.196
CCL20 chemokine (C-C motif) ligand 20 2.195
HSPB8 heat shock 22kDa protein 8 2.195
VLDLR very low density lipoprotein receptor 2.195
UBA1 ubiquitin-like modifier activating enzyme 1 2.193
PDCD1LG2 programmed cell death 1 ligand 2 2.193
HCLS1 hematopoietic cell-specific Lyn substrate 1 2.192
DNM1 dynamin 1 2.192
CUL1 cullin 1 2.192
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.191
CKMT1B creatine kinase, mitochondrial 1B 2.19
IFNA2 interferon, alpha 2 2.19
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.189
NCR3 natural cytotoxicity triggering receptor 3 2.189
MAOB monoamine oxidase B 2.189
AGO2 argonaute RISC catalytic component 2 2.189
IAPP islet amyloid polypeptide 2.189
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.188
BANF1 barrier to autointegration factor 1 2.188
RAB34 RAB34, member RAS oncogene family 2.188
ACO1 aconitase 1, soluble 2.187
E2F1 E2F transcription factor 1 2.187
ACHE acetylcholinesterase (Yt blood group) 2.187
STAT2 signal transducer and activator of transcription 2, 113kDa 2.187
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.186
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 2.186
NCF1 neutrophil cytosolic factor 1 2.186
IRF5 interferon regulatory factor 5 2.186
YIPF1 Yip1 domain family, member 1 2.186
FGF13 fibroblast growth factor 13 2.185
LGALS9 lectin, galactoside-binding, soluble, 9 2.185
C5AR1 complement component 5a receptor 1 2.183
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.183
MX1 MX dynamin-like GTPase 1 2.183
MCU mitochondrial calcium uniporter 2.183
PGK1 phosphoglycerate kinase 1 2.182
VAC14 Vac14 homolog (S. cerevisiae) 2.182
RAB22A RAB22A, member RAS oncogene family 2.181
HDAC1 histone deacetylase 1 2.181
CORO1A coronin, actin binding protein, 1A 2.181
SNX3 sorting nexin 3 2.181
NCSTN nicastrin 2.181
SKP1 S-phase kinase-associated protein 1 2.18
CLCN3 chloride channel, voltage-sensitive 3 2.18
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.179
GNS glucosamine (N-acetyl)-6-sulfatase 2.178
XDH xanthine dehydrogenase 2.178
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 2.177
NANOG Nanog homeobox 2.177
CLCN5 chloride channel, voltage-sensitive 5 2.177
LIPE lipase, hormone-sensitive 2.177
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 2.175
LMBRD1 LMBR1 domain containing 1 2.175
IFITM1 interferon induced transmembrane protein 1 2.174
NEU3 sialidase 3 (membrane sialidase) 2.173
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.173
KITLG KIT ligand 2.173
TG thyroglobulin 2.172
PLAT plasminogen activator, tissue 2.172
SESN1 sestrin 1 2.172
SLC39A8 solute carrier family 39 (zinc transporter), member 8 2.172
CTSV cathepsin V 2.171
IRF8 interferon regulatory factor 8 2.17
PDIA3 protein disulfide isomerase family A, member 3 2.169
TRPV1 transient receptor potential cation channel, subfamily V, member 1 2.168
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.167
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.166
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.166
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.166
DHFR dihydrofolate reductase 2.166
MMP13 matrix metallopeptidase 13 2.165
PPIG peptidylprolyl isomerase G (cyclophilin G) 2.164
VCL vinculin 2.164
FNIP1 folliculin interacting protein 1 2.163
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.163
VTN vitronectin 2.163
HAVCR1 hepatitis A virus cellular receptor 1 2.161
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.161
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 2.161
CISH cytokine inducible SH2-containing protein 2.16
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.16
CDH5 cadherin 5, type 2 (vascular endothelium) 2.157
PPT2 palmitoyl-protein thioesterase 2 2.156
ERBB4 erb-b2 receptor tyrosine kinase 4 2.156
CCN2 cellular communication network factor 2 2.156
BAG1 BCL2-associated athanogene 2.155
PLK1 polo-like kinase 1 2.155
CCNB1 cyclin B1 2.155
C1QA complement component 1, q subcomponent, A chain 2.155
STARD3 StAR-related lipid transfer (START) domain containing 3 2.154
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.153
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 2.153
PCSK1 proprotein convertase subtilisin/kexin type 1 2.152
CXCL11 chemokine (C-X-C motif) ligand 11 2.152
ATF3 activating transcription factor 3 2.151
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 2.151
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 2.151
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.15
EPHA2 EPH receptor A2 2.148
RAB5C RAB5C, member RAS oncogene family 2.148
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.148
H2BC21 H2B clustered histone 21 2.148
EZR ezrin 2.147
TGFBR1 transforming growth factor, beta receptor 1 2.147
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.146
DNMT1 DNA (cytosine-5-)-methyltransferase 1 2.145
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.145
SIRT6 sirtuin 6 2.144
ALK anaplastic lymphoma receptor tyrosine kinase 2.144
LMAN1 lectin, mannose-binding, 1 2.143
FGF21 fibroblast growth factor 21 2.143
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.143
RAB9A RAB9A, member RAS oncogene family 2.142
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.141
IRAK4 interleukin-1 receptor-associated kinase 4 2.141
RHOT1 ras homolog family member T1 2.14
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.14
NEU2 sialidase 2 (cytosolic sialidase) 2.14
DEPDC5 DEP domain containing 5 2.14
SH2D3A SH2 domain containing 3A 2.139
TERT telomerase reverse transcriptase 2.138
CFL2 cofilin 2 (muscle) 2.138
CD59 CD59 molecule, complement regulatory protein 2.137
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2.137
TBX21 T-box 21 2.137
PLD2 phospholipase D2 2.136
BIRC2 baculoviral IAP repeat containing 2 2.135
NES nestin 2.135
G6PC1 glucose-6-phosphatase catalytic subunit 1 2.135
EGR1 early growth response 1 2.134
AGTR1 angiotensin II receptor, type 1 2.134
MMUT methylmalonyl-CoA mutase 2.134
NRBF2 nuclear receptor binding factor 2 2.133