M Phase Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
Description A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. (Gene Ontology, GO_0000279)
External Link https://reactome.org/PathwayBrowser/#/R-HSA-68886
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Genes

372 proteins participating in the M Phase pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
ADRM1 adhesion regulating molecule 1
AHCTF1 AT hook containing transcription factor 1
AKAP9 A kinase (PRKA) anchor protein 9
ALMS1 Alstrom syndrome protein 1
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC15 anaphase promoting complex subunit 15
ANAPC16 anaphase promoting complex subunit 16
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ANKLE2 ankyrin repeat and LEM domain containing 2
ARPP19 cAMP-regulated phosphoprotein, 19kDa
AURKB aurora kinase B
B9D2 B9 protein domain 2
BANF1 barrier to autointegration factor 1
BIRC5 baculoviral IAP repeat containing 5
BLZF1 basic leucine zipper nuclear factor 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CC2D1B coiled-coil and C2 domain containing 1B
CCNB1 cyclin B1
CCNB2 cyclin B2
CCP110 centriolar coiled coil protein 110kDa
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDCA5 cell division cycle associated 5
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPA centromere protein A
CENPC centromere protein C
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPH centromere protein H
CENPI centromere protein I
CENPJ centromere protein J
CENPK centromere protein K
CENPL centromere protein L
CENPM centromere protein M
CENPN centromere protein N
CENPO centromere protein O
CENPP centromere protein P
CENPQ centromere protein Q
CENPS-CORT CENPS-CORT readthrough
CENPT centromere protein T
CENPU centromere protein U
CEP131 centrosomal protein 131kDa
CEP135 centrosomal protein 135kDa
CEP152 centrosomal protein 152kDa
CEP164 centrosomal protein 164kDa
CEP192 centrosomal protein 192kDa
CEP250 centrosomal protein 250kDa
CEP290 centrosomal protein 290kDa
CEP41 centrosomal protein 41kDa
CEP43 centrosomal protein 43
CEP57 centrosomal protein 57kDa
CEP63 centrosomal protein 63kDa
CEP70 centrosomal protein 70kDa
CEP72 centrosomal protein 72kDa
CEP76 centrosomal protein 76kDa
CEP78 centrosomal protein 78kDa
CETN2 centrin, EF-hand protein, 2
CHMP2A charged multivesicular body protein 2A
CHMP2B charged multivesicular body protein 2B
CHMP3 charged multivesicular body protein 3
CHMP4A charged multivesicular body protein 4A
CHMP4B charged multivesicular body protein 4B
CHMP4C charged multivesicular body protein 4C
CHMP6 charged multivesicular body protein 6
CHMP7 charged multivesicular body protein 7
CKAP5 cytoskeleton associated protein 5
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CLIP1 CAP-GLY domain containing linker protein 1
CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1
CNTRL centriolin
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTDNEP1 CTD nuclear envelope phosphatase 1
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DCTN3 dynactin 3 (p22)
DSN1 DSN1, MIS12 kinetochore complex component
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
EMD emerin
EML4 echinoderm microtubule associated protein like 4
ENSA endosulfine alpha
ERCC6L excision repair cross-complementation group 6-like
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FBXO5 F-box protein 5
FIRRM FIGNL1 interacting regulator of recombination and mitosis
GOLGA2 golgin A2
GORASP1 golgi reassembly stacking protein 1, 65kDa
GORASP2 golgi reassembly stacking protein 2, 55kDa
H2AB1 H2A.B variant histone 1
H2AC14 H2A clustered histone 14
H2AC18 H2A clustered histone 18
H2AC20 H2A clustered histone 20
H2AC4 H2A clustered histone 4
H2AC6 H2A clustered histone 6
H2AC7 H2A clustered histone 7
H2AJ H2A.J histone
H2AX H2A.X variant histone
H2AZ2 H2A.Z variant histone 2
H2BC1 H2B clustered histone 1
H2BC11 H2B clustered histone 11
H2BC12 H2B clustered histone 12
H2BC12L H2B clustered histone 12 like
H2BC13 H2B clustered histone 13
H2BC14 H2B clustered histone 14
H2BC15 H2B clustered histone 15
H2BC17 H2B clustered histone 17
H2BC21 H2B clustered histone 21
H2BC26 H2B clustered histone 26
H2BC3 H2B clustered histone 3
H2BC4 H2B clustered histone 4
H2BC5 H2B clustered histone 5
H2BC9 H2B clustered histone 9
H3-3A H3.3 histone A
H3-4 H3.4 histone, cluster member
H3C15 H3 clustered histone 15
H3C8 H3 clustered histone 8
H4C1 H4 clustered histone 1
HAUS1 HAUS augmin-like complex, subunit 1
HAUS2 HAUS augmin-like complex, subunit 2
HAUS3 HAUS augmin-like complex, subunit 3
HAUS4 HAUS augmin-like complex, subunit 4
HAUS5 HAUS augmin-like complex, subunit 5
HAUS6 HAUS augmin-like complex, subunit 6
HAUS7 HAUS augmin-like complex, subunit 7
HAUS8 HAUS augmin-like complex, subunit 8
HDAC8 histone deacetylase 8
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
INCENP inner centromere protein antigens 135/155kDa
IST1 increased sodium tolerance 1 homolog (yeast)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
KIF18A kinesin family member 18A
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
KIF2A kinesin heavy chain member 2A
KIF2B kinesin family member 2B
KIF2C kinesin family member 2C
KMT5A lysine methyltransferase 5A
KNL1 kinetochore scaffold 1
KNTC1 kinetochore associated 1
KPNB1 karyopherin (importin) beta 1
LBR lamin B receptor
LEMD2 LEM domain containing 2
LEMD3 LEM domain containing 3
LMNA lamin A/C
LMNB1 lamin B1
LPIN1 lipin 1
LPIN2 lipin 2
LPIN3 lipin 3
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MASTL microtubule associated serine/threonine kinase-like
MAU2 MAU2 sister chromatid cohesion factor
MCPH1 microcephalin 1
MIS12 MIS12 kinetochore complex component
MZT1 mitotic spindle organizing protein 1
MZT2A mitotic spindle organizing protein 2A
MZT2B mitotic spindle organizing protein 2B
NCAPD2 non-SMC condensin I complex, subunit D2
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPG non-SMC condensin I complex, subunit G
NCAPG2 non-SMC condensin II complex, subunit G2
NCAPH non-SMC condensin I complex, subunit H
NCAPH2 non-SMC condensin II complex, subunit H2
NDC1 NDC1 transmembrane nucleoporin
NDC80 NDC80 kinetochore complex component
NDE1 nudE neurodevelopment protein 1
NDEL1 nudE neurodevelopment protein 1-like 1
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEK2 NIMA-related kinase 2
NEK6 NIMA-related kinase 6
NEK7 NIMA-related kinase 7
NEK9 NIMA-related kinase 9
NINL ninein-like
NIPBL Nipped-B homolog (Drosophila)
NME7 NME/NM23 family member 7
NSL1 NSL1, MIS12 kinetochore complex component
NUDC nudC nuclear distribution protein
NUF2 NUF2, NDC80 kinetochore complex component
NUMA1 nuclear mitotic apparatus protein 1
NUP107 nucleoporin 107kDa
NUP133 nucleoporin 133kDa
NUP153 nucleoporin 153kDa
NUP155 nucleoporin 155kDa
NUP160 nucleoporin 160kDa
NUP188 nucleoporin 188kDa
NUP205 nucleoporin 205kDa
NUP210 nucleoporin 210kDa
NUP214 nucleoporin 214kDa
NUP35 nucleoporin 35kDa
NUP37 nucleoporin 37kDa
NUP42 nucleoporin 42
NUP43 nucleoporin 43kDa
NUP50 nucleoporin 50kDa
NUP54 nucleoporin 54kDa
NUP58 nucleoporin 58
NUP62 nucleoporin 62kDa
NUP85 nucleoporin 85kDa
NUP88 nucleoporin 88kDa
NUP93 nucleoporin 93kDa
NUP98 nucleoporin 98kDa
ODF2 outer dense fiber of sperm tails 2
OFD1 oral-facial-digital syndrome 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCM1 pericentriolar material 1
PCNT pericentrin
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PHF8 PHD finger protein 8
PLK1 polo-like kinase 1
PLK4 polo-like kinase 4
PMF1 polyamine-modulated factor 1
POM121 POM121 transmembrane nucleoporin
POM121C POM121 transmembrane nucleoporin C
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTTG1 pituitary tumor-transforming 1
RAB1A RAB1A, member RAS oncogene family
RAB1B RAB1B, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAD21 RAD21 homolog (S. pombe)
RAE1 ribonucleic acid export 1
RAN RAN, member RAS oncogene family
RANBP2 RAN binding protein 2
RANGAP1 Ran GTPase activating protein 1
RB1 retinoblastoma 1
RCC1 regulator of chromosome condensation 1
RCC2 regulator of chromosome condensation 2
RPS27 ribosomal protein S27
RPS27A ribosomal protein S27a
SDCCAG8 serologically defined colon cancer antigen 8
SEC13 SEC13 homolog (S. cerevisiae)
SEH1L SEH1-like (S. cerevisiae)
SEM1 SEM1 26S proteasome subunit
SET SET nuclear proto-oncogene
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGO1 shugoshin 1
SGO2 shugoshin 2
SIRT2 sirtuin 2
SKA1 spindle and kinetochore associated complex subunit 1
SKA2 spindle and kinetochore associated complex subunit 2
SMC1A structural maintenance of chromosomes 1A
SMC2 structural maintenance of chromosomes 2
SMC3 structural maintenance of chromosomes 3
SMC4 structural maintenance of chromosomes 4
SPAST spastin
SPC24 SPC24, NDC80 kinetochore complex component
SPC25 SPC25, NDC80 kinetochore complex component
SPDL1 spindle apparatus coiled-coil protein 1
SSNA1 Sjogren syndrome nuclear autoantigen 1
STAG1 stromal antigen 1
STAG2 stromal antigen 2
SUMO1 small ubiquitin-like modifier 1
TAOK1 TAO kinase 1
TMPO thymopoietin
TNPO1 transportin 1
TPR translocated promoter region, nuclear basket protein
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA3E tubulin, alpha 3e
TUBA4A tubulin, alpha 4a
TUBA4B tubulin, alpha 4b
TUBA8 tubulin, alpha 8
TUBAL3 tubulin, alpha-like 3
TUBB tubulin, beta class I
TUBB1 tubulin, beta 1 class VI
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
TUBB8 tubulin, beta 8 class VIII
TUBB8B tubulin beta 8B
TUBG1 tubulin, gamma 1
TUBG2 tubulin, gamma 2
TUBGCP2 tubulin, gamma complex associated protein 2
TUBGCP3 tubulin, gamma complex associated protein 3
TUBGCP4 tubulin, gamma complex associated protein 4
TUBGCP5 tubulin, gamma complex associated protein 5
TUBGCP6 tubulin, gamma complex associated protein 6
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2I ubiquitin-conjugating enzyme E2I
UBE2S ubiquitin-conjugating enzyme E2S
USO1 USO1 vesicle transport factor
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VRK1 vaccinia related kinase 1
VRK2 vaccinia related kinase 2
WAPL WAPL cohesin release factor
XPO1 exportin 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZW10 zw10 kinetochore protein
ZWILCH zwilch kinetochore protein
ZWINT ZW10 interacting kinetochore protein