M059J Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: malignant glioblastoma; glioma (Cell Line Ontology, CLO_0007445)
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Genes

319 genes with high or low expression in M059J relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
CYTL1 cytokine-like 1 2.53214
PGM3 phosphoglucomutase 3 2.46489
BTN2A1 butyrophilin, subfamily 2, member A1 2.3722
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 2.17638
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 2.10802
MICA MHC class I polypeptide-related sequence A 1.99228
HAUS7 HAUS augmin-like complex, subunit 7 1.97582
MYLK myosin light chain kinase 1.95506
ATG5 autophagy related 5 1.95331
SPDL1 spindle apparatus coiled-coil protein 1 1.9413
THBS1 thrombospondin 1 1.90169
POFUT2 protein O-fucosyltransferase 2 1.81721
RPA2 replication protein A2, 32kDa 1.81634
NT5E 5'-nucleotidase, ecto (CD73) 1.81508
MRPL17 mitochondrial ribosomal protein L17 1.80636
MOXD1 monooxygenase, DBH-like 1 1.79792
ACOT8 acyl-CoA thioesterase 8 1.75232
OCRL oculocerebrorenal syndrome of Lowe 1.72969
TFG TRK-fused gene 1.72783
CLIC4 chloride intracellular channel 4 1.7246
DNASE1L1 deoxyribonuclease I-like 1 1.70648
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.69404
NCAPG2 non-SMC condensin II complex, subunit G2 1.68397
UBE2A ubiquitin-conjugating enzyme E2A 1.68295
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.68248
LMAN1 lectin, mannose-binding, 1 1.67643
KRT34 keratin 34, type I 1.66671
TMEM39A transmembrane protein 39A 1.6536
TMEM158 transmembrane protein 158 (gene/pseudogene) 1.65155
PSG4 pregnancy specific beta-1-glycoprotein 4 1.64397
MRPL18 mitochondrial ribosomal protein L18 1.63103
C1GALT1C1 C1GALT1-specific chaperone 1 1.62844
CHRDL1 chordin-like 1 1.62435
ULBP2 UL16 binding protein 2 1.60455
IL11 interleukin 11 1.59498
CALU calumenin 1.5939
AURKA aurora kinase A 1.59202
SLC39A7 solute carrier family 39 (zinc transporter), member 7 1.59003
MCTS1 malignant T cell amplified sequence 1 1.5713
SEC23A Sec23 homolog A (S. cerevisiae) 1.56881
KRT33A keratin 33A, type I 1.5597
PSG1 pregnancy specific beta-1-glycoprotein 1 1.55829
SAR1A secretion associated, Ras related GTPase 1A 1.55527
VAMP7 vesicle-associated membrane protein 7 1.54478
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 1.53716
FSTL1 follistatin-like 1 1.53551
TPX2 TPX2, microtubule-associated 1.52721
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 1.51314
EMC1 ER membrane protein complex subunit 1 1.51109
CLDND1 claudin domain containing 1 1.50394
ANAPC13 anaphase promoting complex subunit 13 1.50389
POT1 protection of telomeres 1 1.49171
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 1.48548
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 1.48452
SNRPC small nuclear ribonucleoprotein polypeptide C 1.4825
SOCS5 suppressor of cytokine signaling 5 1.47661
G0S2 G0/G1 switch 2 1.47635
BTG3 BTG family, member 3 1.46805
PTGFR prostaglandin F receptor (FP) 1.46557
P3H1 prolyl 3-hydroxylase 1 1.46181
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 1.45744
CETN2 centrin, EF-hand protein, 2 1.44455
RWDD2A RWD domain containing 2A 1.43267
SEC23IP SEC23 interacting protein 1.43259
WDR44 WD repeat domain 44 1.42812
ECI2 enoyl-CoA delta isomerase 2 1.42717
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 1.42553
ARF4 ADP-ribosylation factor 4 1.42101
COL8A1 collagen, type VIII, alpha 1 1.41953

low expression

Symbol Name Standardized Value
BTBD7 BTB (POZ) domain containing 7 -3.53725
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -3.47519
LRRC37A leucine rich repeat containing 37A -3.15257
MGMT O-6-methylguanine-DNA methyltransferase -3.04602
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -3.00753
USP36 ubiquitin specific peptidase 36 -2.9781
ELP6 elongator acetyltransferase complex subunit 6 -2.90117
EMILIN1 elastin microfibril interfacer 1 -2.88823
HAUS2 HAUS augmin-like complex, subunit 2 -2.88615
ITPK1 inositol-tetrakisphosphate 1-kinase -2.87147
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 -2.7992
SEC14L5 SEC14-like 5 (S. cerevisiae) -2.77268
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -2.68056
KIAA0485 uncharacterized LOC57235 -2.63728
DSPP dentin sialophosphoprotein -2.49659
ZNF652 zinc finger protein 652 -2.48206
EPHB6 EPH receptor B6 -2.47165
PDPK1 3-phosphoinositide dependent protein kinase 1 -2.462
PRMT8 protein arginine methyltransferase 8 -2.46134
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -2.44539
TTC21B tetratricopeptide repeat domain 21B -2.42491
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 -2.42074
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 -2.40777
ZNF160 zinc finger protein 160 -2.39941
PCDH12 protocadherin 12 -2.3597
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing -2.34657
TRAK1 trafficking protein, kinesin binding 1 -2.34127
PLGLA plasminogen-like A (pseudogene) -2.3172
PPP4R2 protein phosphatase 4, regulatory subunit 2 -2.31703
IL16 interleukin 16 -2.31523
MPHOSPH8 M-phase phosphoprotein 8 -2.3088
POLR1B polymerase (RNA) I polypeptide B, 128kDa -2.28875
EXOSC1 exosome component 1 -2.26822
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -2.23536
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -2.23325
STXBP2 syntaxin binding protein 2 -2.23313
RBM48 RNA binding motif protein 48 -2.23116
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -2.20702
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.19563
BEST2 bestrophin 2 -2.19466
RPL27A ribosomal protein L27a -2.17522
PRO2964 uncharacterized protein PRO2964 -2.15036
GADD45G growth arrest and DNA-damage-inducible, gamma -2.13724
SFTPB surfactant protein B -2.13527
DBT dihydrolipoamide branched chain transacylase E2 -2.13311
KLHL24 kelch-like family member 24 -2.10269
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa -2.09863
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.09555
GHRHR growth hormone releasing hormone receptor -2.08281
LDB1 LIM domain binding 1 -2.07369
CNR2 cannabinoid receptor 2 (macrophage) -2.07368
CYFIP2 cytoplasmic FMR1 interacting protein 2 -2.0731
CLSPN claspin -2.06188
DHRS12 dehydrogenase/reductase (SDR family) member 12 -2.06168
G6PC2 glucose-6-phosphatase, catalytic, 2 -2.05938
KIAA0040 KIAA0040 -2.03191
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides -2.02181
FLRT2 fibronectin leucine rich transmembrane protein 2 -2.02028
NPR1 natriuretic peptide receptor 1 -2.01809
PRPF19 pre-mRNA processing factor 19 -2.01408
GAS7 growth arrest-specific 7 -1.99237
APOA4 apolipoprotein A-IV -1.98749
AHSA2 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) -1.97969
MYO9A myosin IXA -1.97246
ANGEL1 angel homolog 1 (Drosophila) -1.95544
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -1.94702
PRKDC protein kinase, DNA-activated, catalytic polypeptide -1.94253
RSL1D1 ribosomal L1 domain containing 1 -1.93452
CPLX3 complexin 3 -1.92854
HRH3 histamine receptor H3 -1.89497
TCF15 transcription factor 15 (basic helix-loop-helix) -1.89471
GRB2 growth factor receptor-bound protein 2 -1.88411
PLCH1 phospholipase C, eta 1 -1.88288
CELP carboxyl ester lipase pseudogene -1.87652
AKAP4 A kinase (PRKA) anchor protein 4 -1.87352
CCDC51 coiled-coil domain containing 51 -1.87013
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -1.86363
FOXH1 forkhead box H1 -1.86341
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -1.86163
PCNX pecanex homolog (Drosophila) -1.86045
MSH3 mutS homolog 3 -1.85986
MBL1P mannose-binding lectin (protein A) 1, pseudogene -1.8587
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -1.85546
NAAA N-acylethanolamine acid amidase -1.85129
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 -1.84932
AMDHD2 amidohydrolase domain containing 2 -1.84864
LONRF1 LON peptidase N-terminal domain and ring finger 1 -1.84416
SLC35E3 solute carrier family 35, member E3 -1.84204
HIST1H2BM histone cluster 1, H2bm -1.83482
ADAM21 ADAM metallopeptidase domain 21 -1.83034
PRX periaxin -1.82661
ADGRL3 adhesion G protein-coupled receptor L3 -1.82348
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -1.82172
FDXR ferredoxin reductase -1.82157
TMBIM4 transmembrane BAX inhibitor motif containing 4 -1.82139
TAAR5 trace amine associated receptor 5 -1.81746
CEL carboxyl ester lipase -1.79219
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -1.78627
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -1.78171
HIC2 hypermethylated in cancer 2 -1.7792
PDE4C phosphodiesterase 4C, cAMP-specific -1.77813
CELA3B chymotrypsin-like elastase family, member 3B -1.77736
HIST1H3G histone cluster 1, H3g -1.77428
CEP135 centrosomal protein 135kDa -1.76637
SIM2 single-minded family bHLH transcription factor 2 -1.76127
POU3F1 POU class 3 homeobox 1 -1.75811
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 -1.75048
OMD osteomodulin -1.74673
HRG histidine-rich glycoprotein -1.74188
MCF2L MCF.2 cell line derived transforming sequence-like -1.73294
LRTM1 leucine-rich repeats and transmembrane domains 1 -1.7283
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -1.72102
PPY2P pancreatic polypeptide 2, pseudogene -1.71983
POMC proopiomelanocortin -1.71525
CTTNBP2NL CTTNBP2 N-terminal like -1.70832
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -1.7032
RPS9 ribosomal protein S9 -1.69579
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -1.6929
MTPAP mitochondrial poly(A) polymerase -1.69242
RGS16 regulator of G-protein signaling 16 -1.68923
PAX1 paired box 1 -1.68844
PRSS1 protease, serine, 1 (trypsin 1) -1.68171
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -1.68048
S1PR4 sphingosine-1-phosphate receptor 4 -1.67931
TRIM33 tripartite motif containing 33 -1.67915
HIST3H3 histone cluster 3, H3 -1.67913
UPK3B uroplakin 3B -1.67358
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -1.67345
RPLP1 ribosomal protein, large, P1 -1.66833
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.6627
KAT6B K(lysine) acetyltransferase 6B -1.66199
LCN1 lipocalin 1 -1.66136
ZNF669 zinc finger protein 669 -1.66006
PDE1A phosphodiesterase 1A, calmodulin-dependent -1.65972
SLC35E1 solute carrier family 35, member E1 -1.65877
VAMP8 vesicle-associated membrane protein 8 -1.65859
AKAP1 A kinase (PRKA) anchor protein 1 -1.65354
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -1.63376
EYA3 EYA transcriptional coactivator and phosphatase 3 -1.6305
CA4 carbonic anhydrase IV -1.63015
GLTSCR2 glioma tumor suppressor candidate region gene 2 -1.62223
JAK3 Janus kinase 3 -1.62007
GAREM GRB2 associated, regulator of MAPK1 -1.61823
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.61641
APC2 adenomatosis polyposis coli 2 -1.61582
TPP2 tripeptidyl peptidase II -1.61215
LARS leucyl-tRNA synthetase -1.60562
TRIM17 tripartite motif containing 17 -1.60554
SDAD1 SDA1 domain containing 1 -1.60439
ACTN3 actinin, alpha 3 (gene/pseudogene) -1.60366
INSL6 insulin-like 6 -1.60293
EIF3L eukaryotic translation initiation factor 3, subunit L -1.6026
GGT5 gamma-glutamyltransferase 5 -1.60211
PNMT phenylethanolamine N-methyltransferase -1.59996
MED18 mediator complex subunit 18 -1.59854
CRLF1 cytokine receptor-like factor 1 -1.59663
OR1F1 olfactory receptor, family 1, subfamily F, member 1 -1.59657
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -1.59615
FAM215A family with sequence similarity 215, member A (non-protein coding) -1.59603
XYLB xylulokinase homolog (H. influenzae) -1.5944
NPY neuropeptide Y -1.5938
FOXI1 forkhead box I1 -1.5911
TLE6 transducin-like enhancer of split 6 -1.58982
DIAPH2 diaphanous-related formin 2 -1.58576
TRPA1 transient receptor potential cation channel, subfamily A, member 1 -1.58176
RPAIN RPA interacting protein -1.57909
GPR135 G protein-coupled receptor 135 -1.57392
NEIL1 nei endonuclease VIII-like 1 (E. coli) -1.57312
HIST1H4G histone cluster 1, H4g -1.57178
TAS2R9 taste receptor, type 2, member 9 -1.57082
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -1.5664
SCLY selenocysteine lyase -1.5663
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.56123
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 -1.56021
GSR glutathione reductase -1.55459
ADRA2C adrenoceptor alpha 2C -1.55172
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain -1.55082
HIST1H3J histone cluster 1, H3j -1.5474
PLCB2 phospholipase C, beta 2 -1.5474
UBAP2 ubiquitin associated protein 2 -1.54392
SSTR3 somatostatin receptor 3 -1.54007
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -1.53733
VGLL4 vestigial-like family member 4 -1.53446
ADSL adenylosuccinate lyase -1.53366
LY86 lymphocyte antigen 86 -1.52958
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -1.5276
GYPB glycophorin B (MNS blood group) -1.52495
TMPRSS11D transmembrane protease, serine 11D -1.52436
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -1.52368
FKSG49 FKSG49 -1.52282
TMEM63A transmembrane protein 63A -1.52153
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 -1.52071
RUFY2 RUN and FYVE domain containing 2 -1.52009
NRXN1 neurexin 1 -1.51986
KIAA0894 KIAA0894 protein -1.51337
NECAB2 N-terminal EF-hand calcium binding protein 2 -1.51051
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 -1.5098
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) -1.50537
N4BP3 NEDD4 binding protein 3 -1.50066
HOXD3 homeobox D3 -1.50036
FGL1 fibrinogen-like 1 -1.50019
YY2 YY2 transcription factor -1.49521
TNNC1 troponin C type 1 (slow) -1.49519
ANKRD12 ankyrin repeat domain 12 -1.49059
OR10H3 olfactory receptor, family 10, subfamily H, member 3 -1.48976
APOBR apolipoprotein B receptor -1.48956
ATF7 activating transcription factor 7 -1.48862
TMPRSS2 transmembrane protease, serine 2 -1.48686
CCDC69 coiled-coil domain containing 69 -1.48549
RNF2 ring finger protein 2 -1.48504
AJAP1 adherens junctions associated protein 1 -1.4846
ICAM3 intercellular adhesion molecule 3 -1.48396
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled -1.48217
EP300 E1A binding protein p300 -1.48083
NPFF neuropeptide FF-amide peptide precursor -1.48014
ACAD10 acyl-CoA dehydrogenase family, member 10 -1.47989
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -1.4765
IFT88 intraflagellar transport 88 -1.47495
KRT23 keratin 23, type I -1.47484
RPS20 ribosomal protein S20 -1.47324
TPPP tubulin polymerization promoting protein -1.46596
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 -1.46526
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.46359
SPRR1A small proline-rich protein 1A -1.4623
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -1.46199
SCYL3 SCY1-like 3 (S. cerevisiae) -1.45841
RBM3 RNA binding motif (RNP1, RRM) protein 3 -1.45821
HSPD1 heat shock 60kDa protein 1 (chaperonin) -1.45793
FLRT3 fibronectin leucine rich transmembrane protein 3 -1.45556
MGC40069 uncharacterized protein MGC40069 -1.45253
CTNNA2 catenin (cadherin-associated protein), alpha 2 -1.45074
RPLP0 ribosomal protein, large, P0 -1.4501
APOH apolipoprotein H (beta-2-glycoprotein I) -1.44984
SPATA1 spermatogenesis associated 1 -1.44806
ACO2 aconitase 2, mitochondrial -1.4453
SPON1 spondin 1, extracellular matrix protein -1.44508
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 -1.44294
MAP1A microtubule-associated protein 1A -1.44293
TFF1 trefoil factor 1 -1.43712
HCG18 HLA complex group 18 (non-protein coding) -1.43623
RBM6 RNA binding motif protein 6 -1.43575
FMO6P flavin containing monooxygenase 6 pseudogene -1.43252
OR3A2 olfactory receptor, family 3, subfamily A, member 2 -1.42851
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -1.42451
LRRC8B leucine rich repeat containing 8 family, member B -1.42389
IGKC immunoglobulin kappa constant -1.421
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -1.4192
FRMD4B FERM domain containing 4B -1.41722
SHBG sex hormone-binding globulin -1.41653
FXN frataxin -1.416