MA-43-MR37_1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=1uM (Novartis)
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Genes

556 genes differentially expressed following the MA-43-MR37_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
S100A2 S100 calcium binding protein A2 5.85076
HRNR hornerin 5.68827
TAGLN transgelin 5.17038
MT2A metallothionein 2A 4.47921
TIMP1 TIMP metallopeptidase inhibitor 1 4.30649
MMP10 matrix metallopeptidase 10 2.84013
TMSB10 thymosin beta 10 2.81232
ESM1 endothelial cell-specific molecule 1 2.76956
OCIAD2 OCIA domain containing 2 2.68068
CD63 CD63 molecule 2.08454
S100A6 S100 calcium binding protein A6 2.064
RHOB ras homolog family member B 1.9365
PFN1 profilin 1 1.92635
SNU13 small nuclear ribonucleoprotein 13 1.86051
TM4SF1 transmembrane 4 L six family member 1 1.84344
TMEM156 transmembrane protein 156 1.73035
BCL2A1 BCL2-related protein A1 1.66911
IER3 immediate early response 3 1.65372
ACTG1 actin gamma 1 1.60288
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.5608
FOXD1 forkhead box D1 1.53747
HMGA1 high mobility group AT-hook 1 1.5365
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.5365
UPP1 uridine phosphorylase 1 1.42433
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 1.41711
VIM vimentin 1.40345
CD59 CD59 molecule, complement regulatory protein 1.36581
RHOC ras homolog family member C 1.35218
SLAMF9 SLAM family member 9 1.34883
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.32539
PFDN2 prefoldin subunit 2 1.28186
FN1 fibronectin 1 1.25354
TUBA1C tubulin, alpha 1c 1.10026
MYL12B myosin, light chain 12B, regulatory 1.09735
TMBIM6 transmembrane BAX inhibitor motif containing 6 1.09262
KRT17 keratin 17, type I 1.07944
NME1-NME2 NME1-NME2 readthrough 1.07211
CTSB cathepsin B 1.04749
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 1.04749
GSTO1 glutathione S-transferase omega 1 1.01158
PLAUR plasminogen activator, urokinase receptor 1.01075
KISS1 KiSS-1 metastasis-suppressor 1.00477
RHOA ras homolog family member A 0.99474
MYEOV myeloma overexpressed 0.978827
SMAGP small cell adhesion glycoprotein 0.955016
POTEF POTE ankyrin domain family, member F 0.955016
KRT6A keratin 6A, type II 0.928636
MCL1 myeloid cell leukemia 1 0.928636
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.917449
NDRG1 N-myc downstream regulated 1 0.917432
S100A11 S100 calcium binding protein A11 0.917432
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.890098
CLIC1 chloride intracellular channel 1 0.872466
CCN2 cellular communication network factor 2 0.867675
PPY pancreatic polypeptide 0.86147
GLRX glutaredoxin (thioltransferase) 0.85989
FGF1 fibroblast growth factor 1 (acidic) 0.85387
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.841
PDLIM4 PDZ and LIM domain 4 0.824214
RHOF ras homolog family member F (in filopodia) 0.79783
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.793465
C5ORF46 chromosome 5 open reading frame 46 0.791822
MPRIP myosin phosphatase Rho interacting protein 0.785715
CD44 CD44 molecule (Indian blood group) 0.78114
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.779412
NOP10 NOP10 ribonucleoprotein 0.762713
CAPN2 calpain 2, (m/II) large subunit 0.75862
PRDM1 PR domain containing 1, with ZNF domain 0.745103
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.731166
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.727849
ARHGAP22 Rho GTPase activating protein 22 0.722146
CLMB calcimembrin 0.711924
GNAS GNAS complex locus 0.698675
PMEPA1 prostate transmembrane protein, androgen induced 1 0.69851
TXN2 thioredoxin 2 0.696314
PCSK7 proprotein convertase subtilisin/kexin type 7 0.68886
EIF1 eukaryotic translation initiation factor 1 0.682436
TUBA1A tubulin, alpha 1a 0.680736
CSNK1E casein kinase 1, epsilon 0.67866
CSRP1 cysteine and glycine-rich protein 1 0.676449
FRMD8 FERM domain containing 8 0.661578
TPST1 tyrosylprotein sulfotransferase 1 0.656446
GCNA germ cell nuclear acidic peptidase 0.656375
CRYAB crystallin, alpha B 0.638784
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.637552
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.635635
TRIB3 tribbles pseudokinase 3 0.629912
ANTXR2 anthrax toxin receptor 2 0.629912
ACTG2 actin, gamma 2, smooth muscle, enteric 0.629912
IFI27L2 interferon, alpha-inducible protein 27-like 2 0.629912
LAMC2 laminin, gamma 2 0.628926
TMEM154 transmembrane protein 154 0.627349
CXCL8 chemokine (C-X-C motif) ligand 8 0.612968
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 0.605828
RTN4 reticulon 4 0.594332
TGM2 transglutaminase 2 0.591174
AREG amphiregulin 0.583997
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 0.575522
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.573065
GLIPR1 GLI pathogenesis-related 1 0.572527
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.568575
FKBP1A FK506 binding protein 1A, 12kDa 0.568124
COX6C cytochrome c oxidase subunit VIc 0.567699
IL11 interleukin 11 0.562838
ARPC4-TTLL3 ARPC4-TTLL3 readthrough 0.560769
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.560769
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.556868
MED10 mediator complex subunit 10 0.556092
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.549672
SPNS1 spinster homolog 1 (Drosophila) 0.549509
DVL1 dishevelled segment polarity protein 1 0.543334
MT1E metallothionein 1E 0.542789
ETV5 ets variant 5 0.540966
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.540966
TSPO translocator protein (18kDa) 0.532822
OLAH oleoyl-ACP hydrolase 0.519414
SPOCD1 SPOC domain containing 1 0.519203
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.518004
VGF VGF nerve growth factor inducible 0.516271
RHOG ras homolog family member G 0.515652
DOCK4 dedicator of cytokinesis 4 0.515652
FXYD5 FXYD domain containing ion transport regulator 5 0.496929
EPHA4 EPH receptor A4 0.495824
NLRP3 NLR family, pyrin domain containing 3 0.491774
SCG5 secretogranin V 0.491774
ATP5F1E ATP synthase F1 subunit epsilon 0.488398
LINC02762 long intergenic non-protein coding RNA 2762 0.486006
POMP proteasome maturation protein 0.482649
KRTAP2-3 keratin associated protein 2-3 0.475732
PLEK2 pleckstrin 2 0.469048
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 0.467473
MFSD2B major facilitator superfamily domain containing 2B 0.464162
RPL22L1 ribosomal protein L22-like 1 0.463393
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.451344
ISG20 interferon stimulated exonuclease gene 20kDa 0.44852
HBEGF heparin-binding EGF-like growth factor 0.438746
PGK1 phosphoglycerate kinase 1 0.436235
SERP1 stress-associated endoplasmic reticulum protein 1 0.435934
SPHK1 sphingosine kinase 1 0.435934
BATF basic leucine zipper transcription factor, ATF-like 0.435934
CTPS1 CTP synthase 1 0.434339
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.42737
CCL3 chemokine (C-C motif) ligand 3 0.421507
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.416193
ITGA6 integrin, alpha 6 0.410657
PXDN peroxidasin 0.410138
CCL20 chemokine (C-C motif) ligand 20 0.406125
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.395868
BOLA2B bolA family member 2B 0.394043
ISG15 ISG15 ubiquitin-like modifier 0.391459
XAGE1A X antigen family member 1A 0.390566
TTC9B tetratricopeptide repeat domain 9B 0.389658
ETV4 ets variant 4 0.387978
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.38176
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.380576
SAR1A secretion associated, Ras related GTPase 1A 0.37782
TXNDC17 thioredoxin domain containing 17 0.368749
CLTB clathrin, light chain B 0.365707
TUBB6 tubulin, beta 6 class V 0.360857
PRDX1 peroxiredoxin 1 0.360381
ITGB5 integrin, beta 5 0.360381
S100A10 S100 calcium binding protein A10 0.356913
RPL31 ribosomal protein L31 0.35528
C11ORF91 chromosome 11 open reading frame 91 0.352088
CYSTM1 cysteine-rich transmembrane module containing 1 0.345572
KRT34 keratin 34, type I 0.344001
DNMBP dynamin binding protein 0.344001
CST3 cystatin C 0.34011
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.338017
FGF5 fibroblast growth factor 5 0.337542
DEF8 differentially expressed in FDCP 8 homolog (mouse) 0.336246
IL24 interleukin 24 0.331014
SPRR2D small proline-rich protein 2D 0.330917
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.329776
NPAS2 neuronal PAS domain protein 2 0.327663
ATOX1 antioxidant 1 copper chaperone 0.323931
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 0.321682
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.319513
CIB1 calcium and integrin binding 1 (calmyrin) 0.319254
DSTN destrin (actin depolymerizing factor) 0.317778
ERRFI1 ERBB receptor feedback inhibitor 1 0.317214
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.312485
SH3KBP1 SH3-domain kinase binding protein 1 0.312274
TMEM171 transmembrane protein 171 0.311218
RNF145 ring finger protein 145 0.31026
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.306305
COL4A1 collagen, type IV, alpha 1 0.305861
UFM1 ubiquitin-fold modifier 1 0.303083
MTCH1 mitochondrial carrier 1 0.301275
HPCAL1 hippocalcin-like 1 0.301236
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.300537
EMP1 epithelial membrane protein 1 0.300537
GUK1 guanylate kinase 1 0.297843
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.295172
UBC ubiquitin C 0.291778
ASL argininosuccinate lyase 0.287245
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.285738
ATP5F1B ATP synthase F1 subunit beta 0.283323
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.283067
ZYX zyxin 0.283021
SEC61B Sec61 beta subunit 0.282687
SYPL1 synaptophysin-like 1 0.281008
RPS13 ribosomal protein S13 0.280168
TPM4 tropomyosin 4 0.279807
LRP10 low density lipoprotein receptor-related protein 10 0.276473
MRPL41 mitochondrial ribosomal protein L41 0.275291
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.274963
TUBA1B tubulin, alpha 1b 0.274164
PLEC plectin 0.271174
OSBP2 oxysterol binding protein 2 0.269161
SPRY2 sprouty homolog 2 (Drosophila) 0.26911
ITM2C integral membrane protein 2C 0.268858
MGST3 microsomal glutathione S-transferase 3 0.267829
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.266756
DUSP12 dual specificity phosphatase 12 0.266427
SELENOK selenoprotein K 0.266083
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 0.264915
LAMB3 laminin, beta 3 0.262883
RSL24D1 ribosomal L24 domain containing 1 0.26169
PLXNA2 plexin A2 0.260234
SELENOS selenoprotein S 0.25975
EXTL3 exostosin-like glycosyltransferase 3 0.257623
LRRC8A leucine rich repeat containing 8 family, member A 0.257623
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.256974
DUSP7 dual specificity phosphatase 7 0.25572
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.255194
KLF6 Kruppel-like factor 6 0.253853
PLIN3 perilipin 3 0.253399
MAX MYC associated factor X 0.249919
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.249726
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.249726
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.246544
LDHA lactate dehydrogenase A 0.246291
CD9 CD9 molecule 0.245962
TOX4 TOX high mobility group box family member 4 0.245106
TUBB2A tubulin, beta 2A class IIa 0.244612
KRT81 keratin 81, type II 0.244612
SRPX sushi-repeat containing protein, X-linked 0.2427
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.2427
RFTN1 raftlin, lipid raft linker 1 0.242498
MRPL36 mitochondrial ribosomal protein L36 0.242313
HINT1 histidine triad nucleotide binding protein 1 0.242253
THBS1 thrombospondin 1 0.24096
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 0.239365
SEC61G Sec61 gamma subunit 0.239077
COTL1 coactosin-like F-actin binding protein 1 0.237507
CD274 CD274 molecule 0.23668
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.23531
TXNRD1 thioredoxin reductase 1 0.23531
KIAA1549L KIAA1549-like 0.233627
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 0.233466
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.23343
IGFBP6 insulin-like growth factor binding protein 6 0.232784
IFFO1 intermediate filament family orphan 1 0.231954
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.231931
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.231931
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.231931
UBALD2 UBA-like domain containing 2 0.230909
BTN3A3 butyrophilin, subfamily 3, member A3 0.230317
FHOD1 formin homology 2 domain containing 1 0.230242
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.230116
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.229817
RNF181 ring finger protein 181 0.228801
SUN3 Sad1 and UNC84 domain containing 3 0.228123
PDPN podoplanin 0.2281
NDUFA4 NDUFA4, mitochondrial complex associated 0.227455
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.227052
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.226718
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.225984
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.225553
KRT15 keratin 15, type I 0.225553
CD40 CD40 molecule, TNF receptor superfamily member 5 0.225553
MSN moesin 0.224276
PTPRE protein tyrosine phosphatase, receptor type, E 0.223829
MAP2K1 mitogen-activated protein kinase kinase 1 0.221195
ANOS1 anosmin 1 0.221117
MT1H metallothionein 1H 0.22033
TMEM200A transmembrane protein 200A 0.219499
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.219499
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) 0.219499
CDC42 cell division cycle 42 0.219499
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.217884
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.217884
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.217382
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.217382
RPL37 ribosomal protein L37 0.216191
RPL39 ribosomal protein L39 0.215998
SFXN3 sideroflexin 3 0.214676
RPL38 ribosomal protein L38 0.214337
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.213844
KLF2 Kruppel-like factor 2 0.212171
PRNP prion protein 0.21115
SERTAD1 SERTA domain containing 1 0.21115
LEPROTL1 leptin receptor overlapping transcript-like 1 0.210466
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 0.209289
MAP7D1 MAP7 domain containing 1 0.209117
TPD52L2 tumor protein D52-like 2 0.208416
PTRH2 peptidyl-tRNA hydrolase 2 0.206579
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.206235
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.205487
TMED2 transmembrane emp24 domain trafficking protein 2 0.202949
AGO2 argonaute RISC catalytic component 2 0.202338
BIRC2 baculoviral IAP repeat containing 2 0.201912
SPRED2 sprouty-related, EVH1 domain containing 2 0.201791
TSPAN5 tetraspanin 5 0.20127
SUB1 SUB1 homolog (S. cerevisiae) 0.20127
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.200809

decreased expression

Symbol Name Standardized Value
CLPTM1L CLPTM1-like -5.85076
DHRS2 dehydrogenase/reductase (SDR family) member 2 -5.77465
EDN2 endothelin 2 -5.75855
PCLO piccolo presynaptic cytomatrix protein -4.15376
CPA4 carboxypeptidase A4 -2.89465
CENPM centromere protein M -2.56916
MAGED1 melanoma antigen family D1 -2.36388
PDLIM1 PDZ and LIM domain 1 -2.14779
TNNI3 troponin I type 3 (cardiac) -2.12852
FDXR ferredoxin reductase -1.9373
TRIP6 thyroid hormone receptor interactor 6 -1.68331
ALOX5 arachidonate 5-lipoxygenase -1.65285
KRT80 keratin 80, type II -1.5365
LOXL1 lysyl oxidase-like 1 -1.53222
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -1.49429
GPC1 glypican 1 -1.49429
MDK midkine (neurite growth-promoting factor 2) -1.45421
AP1M2 adaptor-related protein complex 1, mu 2 subunit -1.43577
TPM1 tropomyosin 1 (alpha) -1.36938
HAPLN1 hyaluronan and proteoglycan link protein 1 -1.32669
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -1.28488
TK1 thymidine kinase 1, soluble -1.28186
GSTM4 glutathione S-transferase mu 4 -1.25744
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -1.23701
ZNF404 zinc finger protein 404 -1.23574
F2R coagulation factor II (thrombin) receptor -1.21715
CD70 CD70 molecule -1.21715
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -1.15255
MN1 meningioma (disrupted in balanced translocation) 1 -1.10604
ZXDB zinc finger, X-linked, duplicated B -1.09727
TMEM37 transmembrane protein 37 -1.0905
AKIP1 A kinase (PRKA) interacting protein 1 -1.01256
CDK4 cyclin-dependent kinase 4 -0.989302
PCLAF PCNA clamp associated factor -0.975872
STMN1 stathmin 1 -0.950682
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.933566
WNT11 wingless-type MMTV integration site family, member 11 -0.929538
FZD2 frizzled class receptor 2 -0.926631
MCM6 minichromosome maintenance complex component 6 -0.901243
LOXL4 lysyl oxidase-like 4 -0.887843
ACKR3 atypical chemokine receptor 3 -0.887154
C1ORF198 chromosome 1 open reading frame 198 -0.885786
MOV10 Mov10 RISC complex RNA helicase -0.885771
SSC4D scavenger receptor cysteine rich family, 4 domains -0.86668
RNF187 ring finger protein 187 -0.86147
TMSB4X thymosin beta 4, X-linked -0.841608
CXCL14 chemokine (C-X-C motif) ligand 14 -0.820746
DDB2 damage-specific DNA binding protein 2, 48kDa -0.818251
FHL2 four and a half LIM domains 2 -0.815595
TMEM45A transmembrane protein 45A -0.785715
PLK2 polo-like kinase 2 -0.769901
MCM7 minichromosome maintenance complex component 7 -0.76706
MCM3 minichromosome maintenance complex component 3 -0.737746
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.730193
BMP4 bone morphogenetic protein 4 -0.719438
ANXA8L1 annexin A8-like 1 -0.704137
COL16A1 collagen, type XVI, alpha 1 -0.699454
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.69851
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.690065
TNNT2 troponin T type 2 (cardiac) -0.666988
ANAPC7 anaphase promoting complex subunit 7 -0.645112
NIPSNAP1 nipsnap homolog 1 (C. elegans) -0.639047
LAYN layilin -0.621475
JUND jun D proto-oncogene -0.616989
C1QTNF12 C1q and TNF related 12 -0.616421
ERI3 ERI1 exoribonuclease family member 3 -0.612968
RHOBTB3 Rho-related BTB domain containing 3 -0.612032
SDC1 syndecan 1 -0.611026
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.61
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -0.601701
DDIT4 DNA-damage-inducible transcript 4 -0.592969
TRIM16 tripartite motif containing 16 -0.591814
NFIB nuclear factor I/B -0.587614
BAX BCL2-associated X protein -0.585289
NINJ1 ninjurin 1 -0.575707
CHD4 chromodomain helicase DNA binding protein 4 -0.565557
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.563105
PTMA prothymosin, alpha -0.560769
MAB21L4 mab-21 like 4 -0.559506
MARCKSL1 MARCKS-like 1 -0.557807
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.556336
TGFB2 transforming growth factor, beta 2 -0.554523
LMNB2 lamin B2 -0.553183
GSDMD gasdermin D -0.537136
SAC3D1 SAC3 domain containing 1 -0.537136
BABAM2 BRISC and BRCA1 A complex member 2 -0.532142
LAMA5 laminin, alpha 5 -0.524534
TYMS thymidylate synthetase -0.519121
GPX1 glutathione peroxidase 1 -0.518004
PRPF19 pre-mRNA processing factor 19 -0.514776
TUBB tubulin, beta class I -0.513437
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.509727
FOXS1 forkhead box S1 -0.509727
ABLIM1 actin binding LIM protein 1 -0.507965
THOC6 THO complex 6 -0.499485
GAMT guanidinoacetate N-methyltransferase -0.496786
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.490257
UBL4A ubiquitin-like 4A -0.475732
UBTF upstream binding transcription factor, RNA polymerase I -0.475338
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -0.474315
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.466466
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -0.46599
TEDC2 tubulin epsilon and delta complex 2 -0.455622
ASF1B anti-silencing function 1B histone chaperone -0.445633
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.443159
SLPI secretory leukocyte peptidase inhibitor -0.441869
TRIM28 tripartite motif containing 28 -0.441443
SYNPO synaptopodin -0.432715
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -0.431522
MRPL30 mitochondrial ribosomal protein L30 -0.431356
NPPB natriuretic peptide B -0.430949
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -0.429925
RASL10B RAS-like, family 10, member B -0.42737
RRM2 ribonucleotide reductase M2 -0.426547
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.42408
ANXA10 annexin A10 -0.414736
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -0.411524
NXN nucleoredoxin -0.410657
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.408536
NONO non-POU domain containing, octamer-binding -0.405865
SMG9 SMG9 nonsense mediated mRNA decay factor -0.405065
FOXO6 forkhead box O6 -0.405065
ADGRD1 adhesion G protein-coupled receptor D1 -0.399368
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.394043
SLC39A11 solute carrier family 39, member 11 -0.385961
PAOX polyamine oxidase (exo-N4-amino) -0.382962
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.377186
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -0.377087
C1QTNF2 C1q and tumor necrosis factor related protein 2 -0.371801
TUBA3C tubulin, alpha 3c -0.37037
STXBP6 syntaxin binding protein 6 (amisyn) -0.369937
C11ORF71 chromosome 11 open reading frame 71 -0.365025
CCDC28B coiled-coil domain containing 28B -0.359007
CNFN cornifelin -0.352449
COL1A1 collagen, type I, alpha 1 -0.351877
COMTD1 catechol-O-methyltransferase domain containing 1 -0.350672
PNMA6A paraneoplastic Ma antigen family member 6A -0.346851
OLFML3 olfactomedin-like 3 -0.344001
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) -0.343756
TP53 tumor protein p53 -0.336414
SNRPA small nuclear ribonucleoprotein polypeptide A -0.334707
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -0.331014
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.330371
SSRP1 structure specific recognition protein 1 -0.330371
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.32851
SIVA1 SIVA1, apoptosis-inducing factor -0.327548
RAB11FIP4 RAB11 family interacting protein 4 (class II) -0.317089
KHK ketohexokinase (fructokinase) -0.316127
CDCA8 cell division cycle associated 8 -0.316127
CENPF centromere protein F, 350/400kDa -0.314939
CDCA3 cell division cycle associated 3 -0.310558
THAP7 THAP domain containing 7 -0.31026
MCM5 minichromosome maintenance complex component 5 -0.31026
CRABP2 cellular retinoic acid binding protein 2 -0.310196
HSPA1A heat shock 70kDa protein 1A -0.310196
KDM1A lysine (K)-specific demethylase 1A -0.310196
RMI2 RecQ mediated genome instability 2 -0.30994
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.307907
AJUBA ajuba LIM protein -0.306305
INTS1 integrator complex subunit 1 -0.305798
PBX1 pre-B-cell leukemia homeobox 1 -0.302611
CNPY4 canopy FGF signaling regulator 4 -0.301627
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.294624
KPNB1 karyopherin (importin) beta 1 -0.293361
FADS2 fatty acid desaturase 2 -0.292625
MXD3 MAX dimerization protein 3 -0.291729
SHOC1 shortage in chiasmata 1 -0.291057
QPRT quinolinate phosphoribosyltransferase -0.286318
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B -0.283067
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.281008
PLCD1 phospholipase C, delta 1 -0.279911
DYSF dysferlin -0.279911
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -0.279604
MMP24 matrix metallopeptidase 24 (membrane-inserted) -0.276575
NME3 NME/NM23 nucleoside diphosphate kinase 3 -0.276514
PARD3 par-3 family cell polarity regulator -0.276387
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 -0.275859
TMEM106C transmembrane protein 106C -0.275859
CDT1 chromatin licensing and DNA replication factor 1 -0.272614
CKAP4 cytoskeleton-associated protein 4 -0.272614
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.270593
ASS1 argininosuccinate synthase 1 -0.269577
NUAK1 NUAK family, SNF1-like kinase, 1 -0.26911
SH3RF3 SH3 domain containing ring finger 3 -0.268489
B9D1 B9 protein domain 1 -0.267142
NOP53 NOP53 ribosome biogenesis factor -0.266389
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.263238
CNN3 calponin 3, acidic -0.260795
ERG28 ergosterol biosynthesis 28 homolog -0.260143
ZNF580 zinc finger protein 580 -0.260143
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 -0.259104
RUNX2 runt-related transcription factor 2 -0.258555
RAB34 RAB34, member RAS oncogene family -0.256512
HMGB2 high mobility group box 2 -0.256286
FLOT1 flotillin 1 -0.252703
ENO2 enolase 2 (gamma, neuronal) -0.251416
DTYMK deoxythymidylate kinase (thymidylate kinase) -0.249971
PLAC8 placenta-specific 8 -0.248241
NADK2 NAD kinase 2, mitochondrial -0.246544
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 -0.246269
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.2454
BAZ1B bromodomain adjacent to zinc finger domain, 1B -0.245106
KRT8 keratin 8, type II -0.243127
CUEDC2 CUE domain containing 2 -0.242316
AMPH amphiphysin -0.242313
CARM1 coactivator-associated arginine methyltransferase 1 -0.242253
TBCD tubulin folding cofactor D -0.241637
FSTL1 follistatin-like 1 -0.239974
PHGDH phosphoglycerate dehydrogenase -0.238335
PDZD2 PDZ domain containing 2 -0.237948
MFSD3 major facilitator superfamily domain containing 3 -0.237507
LACTB lactamase, beta -0.237507
ROGDI rogdi homolog (Drosophila) -0.237421
KIFC1 kinesin family member C1 -0.23531
MPND MPN domain containing -0.232759
RPL18 ribosomal protein L18 -0.231
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.230495
SAFB scaffold attachment factor B -0.229887
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.229864
TEF thyrotrophic embryonic factor -0.225473
SMAD6 SMAD family member 6 -0.224692
PFKL phosphofructokinase, liver -0.223802
MKI67 marker of proliferation Ki-67 -0.223559
CCDC85B coiled-coil domain containing 85B -0.219499
RBMX RNA binding motif protein, X-linked -0.218832
NUP62 nucleoporin 62kDa -0.215879
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -0.214528
EIF3B eukaryotic translation initiation factor 3, subunit B -0.214382
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B -0.212514
CCBE1 collagen and calcium binding EGF domains 1 -0.21087
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -0.210345
CALR calreticulin -0.209655
EEF2 eukaryotic translation elongation factor 2 -0.209117
APLP1 amyloid beta (A4) precursor-like protein 1 -0.209117
NPPC natriuretic peptide C -0.20856
ARID1A AT rich interactive domain 1A (SWI-like) -0.208054
PARP2 poly (ADP-ribose) polymerase 2 -0.205626
SERTAD4 SERTA domain containing 4 -0.205487
PRPF31 pre-mRNA processing factor 31 -0.205221
HDLBP high density lipoprotein binding protein -0.205221
E2F1 E2F transcription factor 1 -0.204649
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -0.204363
RIPOR2 RHO family interacting cell polarization regulator 2 -0.203655
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.201097
POMZP3 POM121 and ZP3 fusion -0.201096
MOB3B MOB kinase activator 3B -0.200782
GAS6 growth arrest-specific 6 -0.200782
TRIM47 tripartite motif containing 47 -0.200782
NAP1L1 nucleosome assembly protein 1-like 1 -0.200717