MACITENTAN Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description A member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension. (Chemical Entities of Biological Interest Ontology, CHEBI_76607)
External Link https://dgidb.org/results?searchType=drug&searchTerms=MACITENTAN
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Genes

4 interacting proteins for the MACITENTAN drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
EDNRB endothelin receptor type B 1.7644
EDNRA endothelin receptor type A 1.26029
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.980222
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.0607018