MAF Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog|The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 4094)
External Link https://ncbi.nlm.nih.gov/gene/4094
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Genes

499 genes differentially expressed following the MAF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ANXA1 annexin A1 0.0165904
MAL mal, T-cell differentiation protein 0.0164024
ATF3 activating transcription factor 3 0.0147995
LY96 lymphocyte antigen 96 0.0147696
ANXA3 annexin A3 0.0145473
CSTA cystatin A (stefin A) 0.0144364
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0135953
ALCAM activated leukocyte cell adhesion molecule 0.0129049
S100A9 S100 calcium binding protein A9 0.0126663
CA2 carbonic anhydrase II 0.012197
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.0119668
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0119601
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.0118752
S100A8 S100 calcium binding protein A8 0.0118646
IFI27 interferon, alpha-inducible protein 27 0.0115357
RGCC regulator of cell cycle 0.011514
SELL selectin L 0.011235
EVI2A ecotropic viral integration site 2A 0.011135
DEFB1 defensin, beta 1 0.0110734
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0110387
ELL2 elongation factor, RNA polymerase II, 2 0.0109102
HIST1H2AC histone cluster 1, H2ac 0.0109015
PI3 peptidase inhibitor 3, skin-derived 0.0108125
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.01072
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0103749
S100P S100 calcium binding protein P 0.0102127
AK4 adenylate kinase 4 0.0102059
CAV2 caveolin 2 0.0102005
DAZAP2 DAZ associated protein 2 0.0101706
CETN2 centrin, EF-hand protein, 2 0.0100763
CEMIP cell migration inducing protein, hyaluronan binding 0.0100092
AKAP12 A kinase (PRKA) anchor protein 12 0.00995051
CD59 CD59 molecule, complement regulatory protein 0.00994892
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00983904
GYPC glycophorin C (Gerbich blood group) 0.00983211
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00982152
CPVL carboxypeptidase, vitellogenic-like 0.00974733
S100A7 S100 calcium binding protein A7 0.00973005
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00972458
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.00957574
SPRR3 small proline-rich protein 3 0.00943356
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00937967
PEA15 phosphoprotein enriched in astrocytes 15 0.00934847
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00933202
CD48 CD48 molecule 0.00929736
ATG5 autophagy related 5 0.00927117
STOM stomatin 0.00925815
COMMD10 COMM domain containing 10 0.0092136
FZD6 frizzled class receptor 6 0.00920453
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00919317
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00913775
AREG amphiregulin 0.00911777
MRPS33 mitochondrial ribosomal protein S33 0.00909931
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00903365
CFI complement factor I 0.00883879
NCF2 neutrophil cytosolic factor 2 0.00880945
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00879173
TSPAN1 tetraspanin 1 0.00878721
RGS10 regulator of G-protein signaling 10 0.00871875
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 0.00869758
CXCL12 chemokine (C-X-C motif) ligand 12 0.00869192
TMEM230 transmembrane protein 230 0.0086787
KLF4 Kruppel-like factor 4 (gut) 0.00863156
FABP4 fatty acid binding protein 4, adipocyte 0.00862623
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.00856281
IL15 interleukin 15 0.00856021
MED6 mediator complex subunit 6 0.00855009
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00854514
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00847172
HIST1H2BD histone cluster 1, H2bd 0.00841035
POPDC3 popeye domain containing 3 0.0083668
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0083372
STON1 stonin 1 0.00829966
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00829518
EXOC5 exocyst complex component 5 0.00829108
FGF13 fibroblast growth factor 13 0.00822742
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00819923
MYO1C myosin IC 0.00819331
SELENOT selenoprotein T 0.00818991
FOLR1 folate receptor 1 (adult) 0.00817227
TPM4 tropomyosin 4 0.00816012
TP53I3 tumor protein p53 inducible protein 3 0.00812505
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00811375
SCEL sciellin 0.00810925
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00809123
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00798291
YIPF5 Yip1 domain family, member 5 0.00797925
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.0079596
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00794314
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00792414
RCAN1 regulator of calcineurin 1 0.00791233
EAPP E2F-associated phosphoprotein 0.00789959
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.00788958
GCH1 GTP cyclohydrolase 1 0.00788829
CTSS cathepsin S 0.00788363
SPRR1B small proline-rich protein 1B 0.00787119
TRIM22 tripartite motif containing 22 0.00783489
KRT81 keratin 81, type II 0.00783351
PRKCQ protein kinase C, theta 0.00783178
ACP1 acid phosphatase 1, soluble 0.00780303
ISG20 interferon stimulated exonuclease gene 20kDa 0.00780194
PTHLH parathyroid hormone-like hormone 0.00780131
FABP7 fatty acid binding protein 7, brain 0.00774869
FAM198B family with sequence similarity 198, member B 0.00774349
TM4SF1 transmembrane 4 L six family member 1 0.0077141
IFI16 interferon, gamma-inducible protein 16 0.00770502
CAV1 caveolin 1, caveolae protein, 22kDa 0.00770392
SKAP2 src kinase associated phosphoprotein 2 0.00769412
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00764835
CORO1A coronin, actin binding protein, 1A 0.00759471
COPS7A COP9 signalosome subunit 7A 0.00750318
ANXA2P2 annexin A2 pseudogene 2 0.00750263
MCL1 myeloid cell leukemia 1 0.00748515
KRT13 keratin 13, type I 0.00747737
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.00746314
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00744887
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00743869
CLIC5 chloride intracellular channel 5 0.00742994
CGRRF1 cell growth regulator with ring finger domain 1 0.00742154
TRAM1 translocation associated membrane protein 1 0.00741731
RNASE6 ribonuclease, RNase A family, k6 0.0073503
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00733892
PLPBP pyridoxal phosphate binding protein 0.00733864
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00733054
RSL1D1 ribosomal L1 domain containing 1 0.00727681
MYL9 myosin, light chain 9, regulatory 0.00726608
LTF lactotransferrin 0.00726152
PRKCD protein kinase C, delta 0.00725479
EGR2 early growth response 2 0.00725434
SH3YL1 SH3 and SYLF domain containing 1 0.0072534
STK17A serine/threonine kinase 17a 0.0072335
PADI2 peptidyl arginine deiminase, type II 0.0072272
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.00722677
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.00722419
KLK10 kallikrein-related peptidase 10 0.00721624
CD86 CD86 molecule 0.00719965
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00719591
TIGAR TP53 induced glycolysis regulatory phosphatase 0.00719533
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00718345
CLCA4 chloride channel accessory 4 0.00718327
MDFIC MyoD family inhibitor domain containing 0.00718265
RHOB ras homolog family member B 0.00716909
EIF5 eukaryotic translation initiation factor 5 0.00714457
ABLIM1 actin binding LIM protein 1 0.00714161
AGPS alkylglycerone phosphate synthase 0.00711943
TSPAN6 tetraspanin 6 0.00711257
SET SET nuclear proto-oncogene 0.00711187
PRKCH protein kinase C, eta 0.00710817
NMD3 NMD3 ribosome export adaptor 0.00710097
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00707345
KCTD12 potassium channel tetramerization domain containing 12 0.00707105
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0070702
CYB5R4 cytochrome b5 reductase 4 0.00705892
CLEC2B C-type lectin domain family 2, member B 0.00705678
CAST calpastatin 0.0070546
PLSCR1 phospholipid scramblase 1 0.00705067
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00701816
NIBAN1 niban apoptosis regulator 1 0.00701201
CHMP2B charged multivesicular body protein 2B 0.00701133
KRCC1 lysine-rich coiled-coil 1 0.00700641
NRN1 neuritin 1 0.00698713
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00698325
EAF2 ELL associated factor 2 0.00696032
HIGD1A HIG1 hypoxia inducible domain family, member 1A 0.00696016
RSL24D1 ribosomal L24 domain containing 1 0.00695999
ITM2A integral membrane protein 2A 0.00695355
FAS Fas cell surface death receptor 0.00692428
GIMAP6 GTPase, IMAP family member 6 0.0069159
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00689096
ZNF277 zinc finger protein 277 0.00688294
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00686565
PPA1 pyrophosphatase (inorganic) 1 0.00683373
MRPL18 mitochondrial ribosomal protein L18 0.00678276
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00678105
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00677738
REEP5 receptor accessory protein 5 0.00677678
IL18 interleukin 18 0.00677501
RIPK2 receptor-interacting serine-threonine kinase 2 0.00676676
DAXX death-domain associated protein 0.00676644
NRBF2 nuclear receptor binding factor 2 0.00676024
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00675906
SRPRB signal recognition particle receptor, B subunit 0.00674119
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00674088
IL6ST interleukin 6 signal transducer 0.00674055
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00674004
PSAP prosaposin 0.00673829
RMDN1 regulator of microtubule dynamics 1 0.00673445
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00671986
ARHGAP15 Rho GTPase activating protein 15 0.00671348
C1QBP complement component 1, q subcomponent binding protein 0.00670086
BCL2A1 BCL2-related protein A1 0.00667054
LAMP3 lysosomal-associated membrane protein 3 0.00665326
PSAT1 phosphoserine aminotransferase 1 0.00663236
MRPL39 mitochondrial ribosomal protein L39 0.00663223
CLDN8 claudin 8 0.00663159
LGALS13 lectin, galactoside-binding, soluble, 13 0.0066261
SLC35A5 solute carrier family 35, member A5 0.00660329
TSPAN8 tetraspanin 8 0.00660056
PDE4B phosphodiesterase 4B, cAMP-specific 0.00659364
FYB1 FYN binding protein 1 0.00657458
BIRC3 baculoviral IAP repeat containing 3 0.00656973
SNX7 sorting nexin 7 0.00656836
AZIN1 antizyme inhibitor 1 0.00656753
YPEL5 yippee-like 5 (Drosophila) 0.0065405
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.00653362
TRIM16 tripartite motif containing 16 0.00651999
HIKESHI heat shock protein nuclear import factor hikeshi 0.0065175
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00651677
CDC42 cell division cycle 42 0.00651676
APOL2 apolipoprotein L, 2 0.00651431
CALB1 calbindin 1, 28kDa 0.0064827
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00648206
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00647927
MCTS1 malignant T cell amplified sequence 1 0.00646877
SAMHD1 SAM domain and HD domain 1 0.00646825
ASNSD1 asparagine synthetase domain containing 1 0.00645502
ADIRF adipogenesis regulatory factor 0.00644411
ITGA6 integrin, alpha 6 0.0064358
MYO1B myosin IB 0.0064021
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00639967
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00638257
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00635898
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 0.00635869
RHCG Rh family, C glycoprotein 0.0063372
ZMAT3 zinc finger, matrin-type 3 0.00633573
RPL26L1 ribosomal protein L26-like 1 0.00632594
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00632152
CEL carboxyl ester lipase 0.00631481
KLK6 kallikrein-related peptidase 6 0.00631415
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00630963
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00630059
ITGB6 integrin, beta 6 0.0062985
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00629664
C1ORF54 chromosome 1 open reading frame 54 0.00629599
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00627748
ETHE1 ethylmalonic encephalopathy 1 0.00627714
RIOX2 ribosomal oxygenase 2 0.00626504
RDX radixin 0.00626253
CLDND1 claudin domain containing 1 0.00624726
FNTA farnesyltransferase, CAAX box, alpha 0.00623808
FXYD3 FXYD domain containing ion transport regulator 3 0.00623595
GIMAP4 GTPase, IMAP family member 4 0.0062307
GAP43 growth associated protein 43 0.00622604
LY6D lymphocyte antigen 6 complex, locus D 0.00622168
IFNGR1 interferon gamma receptor 1 0.00621476
POT1 protection of telomeres 1 0.00620155
ZFAND1 zinc finger, AN1-type domain 1 0.00620001
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00617764
MRPL33 mitochondrial ribosomal protein L33 0.00617236
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00617201

decreased expression

Symbol Name Standardized Value
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.0118639
STK26 serine/threonine protein kinase 26 -0.0117711
MMP1 matrix metallopeptidase 1 -0.011106
PRAME preferentially expressed antigen in melanoma -0.010975
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0109147
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.0108226
TXLNA taxilin alpha -0.0106411
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0105625
KANK2 KN motif and ankyrin repeat domains 2 -0.0105309
ACADVL acyl-CoA dehydrogenase, very long chain -0.0101498
NAV2 neuron navigator 2 -0.0100284
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00997374
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00993619
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00993506
EML3 echinoderm microtubule associated protein like 3 -0.00956607
STK25 serine/threonine kinase 25 -0.00952132
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00939379
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00933448
EMP3 epithelial membrane protein 3 -0.0093223
MACF1 microtubule-actin crosslinking factor 1 -0.00931773
GNAS GNAS complex locus -0.00893501
SDC3 syndecan 3 -0.00882279
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00877819
SRRT serrate, RNA effector molecule -0.00871095
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00869496
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00866264
TPSAB1 tryptase alpha/beta 1 -0.00864071
TRRAP transformation/transcription domain-associated protein -0.00862755
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.0085076
LY6E lymphocyte antigen 6 complex, locus E -0.00844755
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.00844025
MLPH melanophilin -0.00843412
MFSD10 major facilitator superfamily domain containing 10 -0.00825021
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.0082009
SIDT2 SID1 transmembrane family, member 2 -0.00808738
ADCY1 adenylate cyclase 1 (brain) -0.0080711
CCNF cyclin F -0.00805322
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00804734
PSD3 pleckstrin and Sec7 domain containing 3 -0.00800675
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00797087
FBN2 fibrillin 2 -0.00795304
MAOA monoamine oxidase A -0.00794743
ESR1 estrogen receptor 1 -0.00789907
TBL1X transducin (beta)-like 1X-linked -0.0078813
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.00784186
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.00782586
LTBP2 latent transforming growth factor beta binding protein 2 -0.00780011
CDC20 cell division cycle 20 -0.00779913
ISYNA1 inositol-3-phosphate synthase 1 -0.00777142
CTBP2 C-terminal binding protein 2 -0.00772611
SPRY2 sprouty homolog 2 (Drosophila) -0.00772073
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.00770968
GUSB glucuronidase, beta -0.00770845
SFTPA2 surfactant protein A2 -0.00770592
PILRB paired immunoglobin-like type 2 receptor beta -0.00768765
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00768266
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00767988
FBLN2 fibulin 2 -0.00766828
COLEC12 collectin sub-family member 12 -0.00761509
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.00761091
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00759736
SLIT2 slit homolog 2 (Drosophila) -0.00753785
MOK MOK protein kinase -0.00751375
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00747951
PTCH1 patched 1 -0.00747035
DACH1 dachshund family transcription factor 1 -0.00746174
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00744613
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00743187
MCM7 minichromosome maintenance complex component 7 -0.00739553
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -0.00739277
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.007389
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.00738454
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00735873
ZBTB20 zinc finger and BTB domain containing 20 -0.00732792
NSD2 nuclear receptor binding SET domain protein 2 -0.0073111
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -0.00727821
LMNB2 lamin B2 -0.00726669
BRD4 bromodomain containing 4 -0.00726656
BAG6 BCL2-associated athanogene 6 -0.00725682
NOTCH2 notch 2 -0.00724012
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.00718727
FZD2 frizzled class receptor 2 -0.00718431
INTS1 integrator complex subunit 1 -0.00716949
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.00716404
CDC25B cell division cycle 25B -0.00715204
HOXC10 homeobox C10 -0.00714702
CIT citron rho-interacting serine/threonine kinase -0.0071278
SFTPB surfactant protein B -0.00711414
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00710179
IGFBP1 insulin-like growth factor binding protein 1 -0.00710064
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00705819
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00704142
COL3A1 collagen, type III, alpha 1 -0.0070218
RAPSN receptor-associated protein of the synapse -0.00701382
FASN fatty acid synthase -0.00701372
TNNT1 troponin T type 1 (skeletal, slow) -0.00701078
RBM6 RNA binding motif protein 6 -0.006994
COL16A1 collagen, type XVI, alpha 1 -0.00699288
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00694701
WDR6 WD repeat domain 6 -0.00693886
EXPH5 exophilin 5 -0.00693204
SPON2 spondin 2, extracellular matrix protein -0.00693025
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -0.00693022
GRAMD4 GRAM domain containing 4 -0.00692126
NOTCH2NL notch 2 N-terminal like -0.0069192
DGCR8 DGCR8 microprocessor complex subunit -0.00690908
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.0069054
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00689495
PDZRN3 PDZ domain containing ring finger 3 -0.00687893
RRBP1 ribosome binding protein 1 -0.00685757
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -0.00684703
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00681898
RAB8A RAB8A, member RAS oncogene family -0.00680355
GLA galactosidase, alpha -0.00680096
PRC1 protein regulator of cytokinesis 1 -0.00678793
DYNLL1 dynein, light chain, LC8-type 1 -0.00678743
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00677542
DPY19L1 dpy-19-like 1 (C. elegans) -0.00677337
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.00676984
ANKRD11 ankyrin repeat domain 11 -0.00676176
ATG4B autophagy related 4B, cysteine peptidase -0.00675327
MAEA macrophage erythroblast attacher -0.00673986
SRRM2 serine/arginine repetitive matrix 2 -0.00673446
DVL1 dishevelled segment polarity protein 1 -0.00671626
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00670529
SEC16A SEC16 homolog A (S. cerevisiae) -0.00670215
EDNRA endothelin receptor type A -0.0066869
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00668385
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.00668317
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00667879
PNISR PNN-interacting serine/arginine-rich protein -0.00667816
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -0.00665092
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00664244
HDGF hepatoma-derived growth factor -0.00663498
ITGB5 integrin, beta 5 -0.00661727
DNM1 dynamin 1 -0.00660617
KEAP1 kelch-like ECH-associated protein 1 -0.00656673
VIM vimentin -0.0065572
PCOLCE procollagen C-endopeptidase enhancer -0.0065292
FOXM1 forkhead box M1 -0.00652343
SGSM2 small G protein signaling modulator 2 -0.0065029
CHD4 chromodomain helicase DNA binding protein 4 -0.0065026
PFKM phosphofructokinase, muscle -0.00649895
PLXND1 plexin D1 -0.00649878
PLEC plectin -0.00649277
EIF3B eukaryotic translation initiation factor 3, subunit B -0.00649079
MELK maternal embryonic leucine zipper kinase -0.00649065
RPA1 replication protein A1, 70kDa -0.00646915
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.006465
FUS FUS RNA binding protein -0.00646414
NOTCH1 notch 1 -0.00645916
MAP7 microtubule-associated protein 7 -0.00643939
ZCCHC14 zinc finger, CCHC domain containing 14 -0.00643521
ABHD2 abhydrolase domain containing 2 -0.00642767
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00642364
CUX1 cut-like homeobox 1 -0.00641907
SUGP2 SURP and G patch domain containing 2 -0.00641623
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -0.00641547
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.00640675
TSC2 tuberous sclerosis 2 -0.00639637
MDC1 mediator of DNA-damage checkpoint 1 -0.0063932
PLXNA1 plexin A1 -0.00639257
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.0063854
CD320 CD320 molecule -0.00636048
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00635427
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00633586
GCN1 GCN1 activator of EIF2AK4 -0.00632776
MCM3 minichromosome maintenance complex component 3 -0.0063169
ACTN4 actinin, alpha 4 -0.00631583
ZC3H11A zinc finger CCCH-type containing 11A -0.00631426
IGSF3 immunoglobulin superfamily, member 3 -0.00631264
CPM carboxypeptidase M -0.00630611
CHERP calcium homeostasis endoplasmic reticulum protein -0.00628631
ELN elastin -0.00627395
NCOR2 nuclear receptor corepressor 2 -0.00626577
CBX5 chromobox homolog 5 -0.00625118
LOXL1 lysyl oxidase-like 1 -0.00624712
SLC16A6 solute carrier family 16, member 6 -0.00623898
TGFBR3 transforming growth factor, beta receptor III -0.00623745
SMTN smoothelin -0.00622441
IPO9 importin 9 -0.00622133
TIMELESS timeless circadian clock -0.00622059
COL4A5 collagen, type IV, alpha 5 -0.00621312
INTS3 integrator complex subunit 3 -0.00621198
NBPF10 neuroblastoma breakpoint family, member 10 -0.00619182
CBX6 chromobox homolog 6 -0.00618619
XYLT1 xylosyltransferase I -0.00617077
MACROD1 MACRO domain containing 1 -0.00616107
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.00615807
TUBGCP3 tubulin, gamma complex associated protein 3 -0.00615731
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00615065
THOC2 THO complex 2 -0.00614116
HMG20B high mobility group 20B -0.0061382
SNX1 sorting nexin 1 -0.00613744
NUP107 nucleoporin 107kDa -0.0061352
GPSM2 G-protein signaling modulator 2 -0.00613322
C2CD5 C2 calcium-dependent domain containing 5 -0.00612583
FAM168B family with sequence similarity 168, member B -0.0061139
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00611331
RACGAP1 Rac GTPase activating protein 1 -0.00610074
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.00609735
MPRIP myosin phosphatase Rho interacting protein -0.00609228
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00608254
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.00608211
INPPL1 inositol polyphosphate phosphatase-like 1 -0.00607695
TNS3 tensin 3 -0.00607344
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0060719
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00606246
MICALL2 MICAL-like 2 -0.00606197
ANPEP alanyl (membrane) aminopeptidase -0.00605938
RUFY1 RUN and FYVE domain containing 1 -0.00604798
TGM2 transglutaminase 2 -0.0060421
TBX3 T-box 3 -0.0060268
LAMB1 laminin, beta 1 -0.0060174
VEGFA vascular endothelial growth factor A -0.00601651
UBE2S ubiquitin-conjugating enzyme E2S -0.00601
NUMA1 nuclear mitotic apparatus protein 1 -0.0060054
DROSHA drosha, ribonuclease type III -0.00600421
PRRC2A proline-rich coiled-coil 2A -0.00597769
CLASP1 cytoplasmic linker associated protein 1 -0.00597576
KIAA1109 KIAA1109 -0.00596614
JAG2 jagged 2 -0.00596352
SRSF11 serine/arginine-rich splicing factor 11 -0.00596345
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -0.0059626
CBS cystathionine-beta-synthase -0.00595661
LMNA lamin A/C -0.00595019
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00593667
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.00592909
TDO2 tryptophan 2,3-dioxygenase -0.00592775
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00591383
PFKL phosphofructokinase, liver -0.00590611
PKD1 polycystic kidney disease 1 (autosomal dominant) -0.00590136
ERBB2 erb-b2 receptor tyrosine kinase 2 -0.0058966
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00589284
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.00588923
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00588036
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00587763
CP ceruloplasmin (ferroxidase) -0.00587011
S100A4 S100 calcium binding protein A4 -0.0058696
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -0.00586781
TSPAN4 tetraspanin 4 -0.00584962
PLPP3 phospholipid phosphatase 3 -0.00584835
DLX5 distal-less homeobox 5 -0.0058438
RBM10 RNA binding motif protein 10 -0.00584276
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00583119
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.00581311
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0058072
GTSE1 G-2 and S-phase expressed 1 -0.00579462
SLTM SAFB-like, transcription modulator -0.00579399