MAF Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog|The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 4094)
External Link http://www.ncbi.nlm.nih.gov/gene/4094
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Genes

25 interacting proteins for MAF from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AHR aryl hydrocarbon receptor
ATF4 activating transcription factor 4
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CREBBP CREB binding protein
EP300 E1A binding protein p300
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
HDAC2 histone deacetylase 2
HNF4A hepatocyte nuclear factor 4, alpha
HOXD12 homeobox D12
JUN jun proto-oncogene
KDM5B lysine (K)-specific demethylase 5B
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MYB v-myb avian myeloblastosis viral oncogene homolog
PML promyelocytic leukemia
SIN3A SIN3 transcription regulator family member A
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SOX9 SRY (sex determining region Y)-box 9
SUMO1 small ubiquitin-like modifier 1
UBE2I ubiquitin-conjugating enzyme E2I
USF2 upstream transcription factor 2, c-fos interacting