MAFB Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B|The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9935)
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Genes

329 genes differentially expressed following the MAFB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TSHZ1 teashirt zinc finger homeobox 1 3.21148
MSMP microseminoprotein, prostate associated 3.21148
GATA4 GATA binding protein 4 3.21148
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 3.21148
FAM43B family with sequence similarity 43, member B 3.21148
SLC38A3 solute carrier family 38, member 3 3.21148
GNLY granulysin 3.21148
ARG1 arginase 1 3.21148
HSPB6 heat shock protein, alpha-crystallin-related, B6 3.21148
SPINT4 serine peptidase inhibitor, Kunitz type 4 3.21148
PRSS54 protease, serine, 54 3.21148
MYO16 myosin XVI 3.21148
DRC1 dynein regulatory complex subunit 1 3.21148
EVI2A ecotropic viral integration site 2A 3.21148
CFAP65 cilia and flagella associated protein 65 3.21148
HRG histidine-rich glycoprotein 3.21148
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 3.21148
ZEB2 zinc finger E-box binding homeobox 2 3.19648
HBA1 hemoglobin, alpha 1 3.19648
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 3.19648
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 3.19648
MAGEA3 melanoma antigen family A3 3.19648
SCGB3A1 secretoglobin, family 3A, member 1 3.19648
SPINK6 serine peptidase inhibitor, Kazal type 6 3.19648
SIX6 SIX homeobox 6 3.19648
ELF4 E74-like factor 4 (ets domain transcription factor) 3.19648
IGFL4 IGF-like family member 4 3.19648
CHADL chondroadherin-like 3.19648
COLEC10 collectin sub-family member 10 (C-type lectin) 3.19648
NIPSNAP3B nipsnap homolog 3B (C. elegans) 3.19648
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 3.19648
SLC15A5 solute carrier family 15, member 5 3.19648
NT5E 5'-nucleotidase, ecto (CD73) 3.19648
ACOT12 acyl-CoA thioesterase 12 3.19648
UCN2 urocortin 2 3.19648
OR4D9 olfactory receptor, family 4, subfamily D, member 9 3.19648
C2ORF78 chromosome 2 open reading frame 78 3.19648
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 3.19648
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 3.19648
NWD1 NACHT and WD repeat domain containing 1 3.19648
CRYGA crystallin, gamma A 3.19648
SETSIP SET-like protein 3.19648
ASB14 ankyrin repeat and SOCS box containing 14 3.19648
NEU4 sialidase 4 3.19648
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 3.19648
CA1 carbonic anhydrase I 3.19648
TPSD1 tryptase delta 1 3.19648
PSCA prostate stem cell antigen 3.19648
MAGED4 melanoma antigen family D4 3.19648
SOWAHB sosondowah ankyrin repeat domain family member B 3.19648
CTAG2 cancer/testis antigen 2 3.19648
LOC124906892 uncharacterized LOC124906892 3.19648
C3AR1 complement component 3a receptor 1 3.19648
CD300LF CD300 molecule-like family member f 3.19648
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 3.19648
XKRX XK, Kell blood group complex subunit-related, X-linked 3.19648
ZNF441 zinc finger protein 441 3.19648
KHDC1L KH homology domain containing 1-like 3.19648
NXPE2 neurexophilin and PC-esterase domain family, member 2 3.19648
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 3.19648
GBP6 guanylate binding protein family, member 6 3.19648
PLG plasminogen 3.19648
LOC122526780 uncharacterized LOC122526780 3.19648
H2BW2 H2B.W histone 2 3.19648
TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 3.19648
NSG2 neuronal vesicle trafficking associated 2 3.19648
GASK1B golgi associated kinase 1B 3.19648
SMIM38 small integral membrane protein 38 3.19648
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 3.19648
GIPC3 GIPC PDZ domain containing family, member 3 3.19648
ARHGAP15 Rho GTPase activating protein 15 3.19648
IL1RN interleukin 1 receptor antagonist 3.19648
BLNK B-cell linker 3.19648
OR8D4 olfactory receptor, family 8, subfamily D, member 4 3.19648
DAO D-amino-acid oxidase 3.19648
CLEC3A C-type lectin domain family 3, member A 3.19648
TRIM67 tripartite motif containing 67 3.19648
LGALS7B lectin, galactoside-binding, soluble, 7B 3.19648
ACOT4 acyl-CoA thioesterase 4 3.19648
ACOT8 acyl-CoA thioesterase 8 3.19648
OR2A1 olfactory receptor, family 2, subfamily A, member 1 3.19648
LIX1 Lix1 homolog (chicken) 3.19648
MEOX2 mesenchyme homeobox 2 3.19648
TACR2 tachykinin receptor 2 3.19648
GLIPR1L2 GLI pathogenesis-related 1 like 2 3.19648
S100B S100 calcium binding protein B 3.19648
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 3.19648
PRR18 proline rich 18 3.19648
C1QTNF1 C1q and tumor necrosis factor related protein 1 3.19648
C1QL2 complement component 1, q subcomponent-like 2 3.19648
SH3TC2 SH3 domain and tetratricopeptide repeats 2 3.19648
FPR1 formyl peptide receptor 1 3.19648
TPPP2 tubulin polymerization-promoting protein family member 2 3.19648
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 3.19648
RETNLB resistin like beta 3.19648
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 3.19648
ZNF703 zinc finger protein 703 3.19648
CRHBP corticotropin releasing hormone binding protein 3.19648
MYF6 myogenic factor 6 (herculin) 3.19648
PALMD palmdelphin 3.19648
KRT3 keratin 3, type II 3.19648
RGCC regulator of cell cycle 3.19648
ZIM2 zinc finger, imprinted 2 3.19648
UBXN10 UBX domain protein 10 3.19648
LRRC43 leucine rich repeat containing 43 3.19648
OR8H1 olfactory receptor, family 8, subfamily H, member 1 3.19648
EFCC1 EF-hand and coiled-coil domain containing 1 3.19648
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 3.19648
KLF2 Kruppel-like factor 2 3.19648
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 3.19648
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 3.19648
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 3.19648
EPGN epithelial mitogen 3.19648
FBXO47 F-box protein 47 3.19648
HOPX HOP homeobox 3.19648
HRCT1 histidine rich carboxyl terminus 1 3.19648
AGXT2 alanine--glyoxylate aminotransferase 2 3.19648
SHISA8 shisa family member 8 3.19648
NUPR1 nuclear protein, transcriptional regulator, 1 3.19648
C2CD4D C2 calcium-dependent domain containing 4D 3.19648
DRD3 dopamine receptor D3 3.19648
PGK2 phosphoglycerate kinase 2 3.19648
WFDC6 WAP four-disulfide core domain 6 3.19648
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 3.19648
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 3.19648
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 3.19648
FGF10 fibroblast growth factor 10 3.19648
TRPM5 transient receptor potential cation channel, subfamily M, member 5 3.19648
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 3.19648
GAS2L2 growth arrest-specific 2 like 2 3.19648
EPX eosinophil peroxidase 3.19648
NUTM2D NUT family member 2D 3.19648
TMEM100 transmembrane protein 100 3.19648
CNR2 cannabinoid receptor 2 (macrophage) 3.19648
SFTA2 surfactant associated 2 3.19648
CNGB1 cyclic nucleotide gated channel beta 1 3.19648
TBC1D28 TBC1 domain family, member 28 3.19648
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 3.19648
GOLGA8R golgin A8 family, member R 3.19648
NLRP8 NLR family, pyrin domain containing 8 3.19648
PRRX1 paired related homeobox 1 3.19648
HLA-DMB major histocompatibility complex, class II, DM beta 3.17224
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 3.17224
RAB11B RAB11B, member RAS oncogene family 3.16082
RPS19BP1 ribosomal protein S19 binding protein 1 2.89944
OLFM1 olfactomedin 1 2.85613
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 2.84838
TUT7 terminal uridylyl transferase 7 2.84278
TRUB2 TruB pseudouridine (psi) synthase family member 2 2.81924
ARID1B AT rich interactive domain 1B (SWI1-like) 2.70636
PHF19 PHD finger protein 19 2.70177
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 2.64763
SLCO4C1 solute carrier organic anion transporter family, member 4C1 2.63309
SGSH N-sulfoglucosamine sulfohydrolase 2.60685
PHC1 polyhomeotic homolog 1 (Drosophila) 2.60603
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.58783
TM9SF4 transmembrane 9 superfamily protein member 4 2.55242
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 2.53701
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.50611
ISG15 ISG15 ubiquitin-like modifier 2.42853
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1 2.4266
HARS2 histidyl-tRNA synthetase 2, mitochondrial 2.40103
PRKCD protein kinase C, delta 2.39585
FASTKD3 FAST kinase domains 3 2.3949
VWF von Willebrand factor 2.38295
HYLS1 hydrolethalus syndrome 1 2.38295
NADK2 NAD kinase 2, mitochondrial 2.36609
GTPBP6 GTP binding protein 6 (putative) 2.36519
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 2.35222
DCAF15 DDB1 and CUL4 associated factor 15 2.34368
TTLL12 tubulin tyrosine ligase-like family member 12 2.327
TGM2 transglutaminase 2 2.31204
SYCP3 synaptonemal complex protein 3 2.31204
BTBD7 BTB (POZ) domain containing 7 2.31204
MRPS35 mitochondrial ribosomal protein S35 2.30507
KCTD19 potassium channel tetramerization domain containing 19 2.26516
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.26516
AMN amnion associated transmembrane protein 2.26516
CELF1 CUGBP, Elav-like family member 1 2.26516
PCDHGA11 protocadherin gamma subfamily A, 11 2.26516
RGPD1 RANBP2-like and GRIP domain containing 1 2.26516
ERAS ES cell expressed Ras 2.26516
STAB1 stabilin 1 2.26516
DOLPP1 dolichyldiphosphatase 1 2.22181
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.21362
WDR93 WD repeat domain 93 2.20262
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 2.20262
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 2.19251
TRDMT1 tRNA aspartic acid methyltransferase 1 2.19121
FRY furry homolog (Drosophila) 2.16581
XYLT1 xylosyltransferase I 2.16334
BEGAIN brain-enriched guanylate kinase-associated 2.15183
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.13
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 2.13
TMEM243 transmembrane protein 243, mitochondrial 2.10113
MRPL33 mitochondrial ribosomal protein L33 2.10021
DPYS dihydropyrimidinase 2.07712
HARBI1 harbinger transposase derived 1 2.07341
SLITRK4 SLIT and NTRK-like family, member 4 2.07341
TSPYL4 TSPY-like 4 2.06816
TSPAN14 tetraspanin 14 2.06816
GHITM growth hormone inducible transmembrane protein 2.06816
TNRC18 trinucleotide repeat containing 18 2.06773
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 2.05972
ZNF394 zinc finger protein 394 2.0568
ZNF114 zinc finger protein 114 2.05133
FXR1 fragile X mental retardation, autosomal homolog 1 2.04924
ZSCAN10 zinc finger and SCAN domain containing 10 2.04924
CIB1 calcium and integrin binding 1 (calmyrin) 2.04924
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2.04215
DTNA dystrobrevin, alpha 2.04086
HOMEZ homeobox and leucine zipper encoding 2.04006
MRPS7 mitochondrial ribosomal protein S7 2.03839
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.01616
TRIM26 tripartite motif containing 26 2.005

decreased expression

Symbol Name Standardized Value
AQP4 aquaporin 4 -3.21148
LRRC36 leucine rich repeat containing 36 -3.21148
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -3.21148
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 -3.21148
GOLGA6L10 golgin A6 family-like 10 -3.21148
LBHD1 LBH domain containing 1 -3.21148
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 -3.21148
ZNF597 zinc finger protein 597 -3.21148
MYH2 myosin, heavy chain 2, skeletal muscle, adult -3.21148
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 -3.19648
CCDC152 coiled-coil domain containing 152 -3.17224
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E -3.17224
TMEM132D transmembrane protein 132D -3.17224
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -3.17224
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 -3.17224
SLC26A7 solute carrier family 26 (anion exchanger), member 7 -3.17224
CPB2 carboxypeptidase B2 (plasma) -3.17224
GPRC5D G protein-coupled receptor, class C, group 5, member D -3.17224
SGMS2 sphingomyelin synthase 2 -3.17224
PRSS21 protease, serine, 21 (testisin) -3.17224
EVPL envoplakin -3.17224
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 -3.17224
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) -3.17224
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 -3.17224
YY2 YY2 transcription factor -3.17224
SLITRK5 SLIT and NTRK-like family, member 5 -3.17224
SHISA3 shisa family member 3 -3.17224
C11ORF91 chromosome 11 open reading frame 91 -3.17224
ADIRF adipogenesis regulatory factor -3.17224
LTB lymphotoxin beta (TNF superfamily, member 3) -3.17224
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 -3.17224
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -3.17224
HLA-G major histocompatibility complex, class I, G -3.17224
PCDHAC2 protocadherin alpha subfamily C, 2 -3.17224
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 -3.17224
TMEM225B transmembrane protein 225B -3.17224
LY6L lymphocyte antigen 6 family member L -3.17224
PRRT4 proline-rich transmembrane protein 4 -3.17224
RRM1 ribonucleotide reductase M1 -3.17224
ADGRG1 adhesion G protein-coupled receptor G1 -3.17224
ERICH6B glutamate-rich 6B -3.17224
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -3.17224
FAM177B family with sequence similarity 177, member B -3.17224
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -3.17224
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 -3.17224
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -3.17224
IFT70A intraflagellar transport 70A -3.17224
INSYN1 inhibitory synaptic factor 1 -3.17224
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.15838
AGGF1 angiogenic factor with G patch and FHA domains 1 -2.83449
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.82578
MGAT4C MGAT4 family, member C -2.74997
TADA2B transcriptional adaptor 2B -2.70636
FAM91A1 family with sequence similarity 91, member A1 -2.66315
NUDCD3 NudC domain containing 3 -2.63923
TMEM218 transmembrane protein 218 -2.54256
TAS2R30 taste receptor, type 2, member 30 -2.51894
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.51596
CLBA1 clathrin binding box of aftiphilin containing 1 -2.43578
C18ORF54 chromosome 18 open reading frame 54 -2.43564
STK38L serine/threonine kinase 38 like -2.39585
LSMEM2 leucine-rich single-pass membrane protein 2 -2.38179
ZNF843 zinc finger protein 843 -2.37029
GDA guanine deaminase -2.37029
PLK5 polo-like kinase 5 -2.37029
ZNF343 zinc finger protein 343 -2.37029
EYA4 EYA transcriptional coactivator and phosphatase 4 -2.37029
AGBL1 ATP/GTP binding protein-like 1 -2.37029
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 -2.37029
HDAC8 histone deacetylase 8 -2.3546
RAD54L2 RAD54-like 2 (S. cerevisiae) -2.35331
RAD9A RAD9 homolog A (S. pombe) -2.35208
MED20 mediator complex subunit 20 -2.327
PWWP3B PWWP domain containing 3B -2.30816
H2AJ H2A.J histone -2.30816
WWC1 WW and C2 domain containing 1 -2.3016
DGKI diacylglycerol kinase, iota -2.29348
FREM1 FRAS1 related extracellular matrix 1 -2.29348
RBM6 RNA binding motif protein 6 -2.28663
UHRF1 ubiquitin-like with PHD and ring finger domains 1 -2.26516
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 -2.26516
IKZF3 IKAROS family zinc finger 3 (Aiolos) -2.23754
TP73 tumor protein p73 -2.23754
RBKS ribokinase -2.23754
MARCKS myristoylated alanine-rich protein kinase C substrate -2.23754
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 -2.23754
H4C2 H4 clustered histone 2 -2.22181
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 -2.20262
MTCH2 mitochondrial carrier 2 -2.19121
CFAP69 cilia and flagella associated protein 69 -2.19121
DICER1 dicer 1, ribonuclease type III -2.15065
ZFP3 ZFP3 zinc finger protein -2.13
SCUBE3 signal peptide, CUB domain, EGF-like 3 -2.13
SCT secretin -2.13
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -2.13
OMD osteomodulin -2.13
KATNA1 katanin p60 (ATPase containing) subunit A 1 -2.1286
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -2.10417
JUP junction plakoglobin -2.08917
SYT12 synaptotagmin XII -2.07346
CD79B CD79b molecule, immunoglobulin-associated beta -2.07341
NPM2 nucleophosmin/nucleoplasmin 2 -2.07341
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 -2.07341
PGBD4 piggyBac transposable element derived 4 -2.07341
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -2.07341
PDIA5 protein disulfide isomerase family A, member 5 -2.06816
ZNRF3 zinc and ring finger 3 -2.06816
TTC26 tetratricopeptide repeat domain 26 -2.06816
ARF1 ADP-ribosylation factor 1 -2.04924
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -2.04924
TEFM transcription elongation factor, mitochondrial -2.0469
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 -2.02716
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -2.01616
MAP1S microtubule-associated protein 1S -2.01153