MAFG Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G|Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM, Mar 2010] (NCBI Entrez Gene Database, 4097)
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Genes

305 genes differentially expressed following the MAFG gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
LRTM3 leucine rich repeat transmembrane protein 3 3.8518
LYZL6 lysozyme-like 6 3.8518
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 3.8518
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 3.8518
KHDC3L KH domain containing 3-like, subcortical maternal complex member 3.8518
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 3.8518
BFSP2 beaded filament structural protein 2, phakinin 3.8518
ASCL2 achaete-scute family bHLH transcription factor 2 3.8518
TGM6 transglutaminase 6 3.8518
MORC1 MORC family CW-type zinc finger 1 3.8518
TREH trehalase (brush-border membrane glycoprotein) 3.8518
SLC15A5 solute carrier family 15, member 5 3.8518
PAX7 paired box 7 3.8518
THSD8 thrombospondin type 1 domain containing 8 3.8518
ARMC12 armadillo repeat containing 12 3.8518
C1QTNF8 C1q and tumor necrosis factor related protein 8 3.8518
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 3.8518
ZNF575 zinc finger protein 575 3.8518
FOXD1 forkhead box D1 3.8518
KLHL35 kelch-like family member 35 3.8518
CNTNAP4 contactin associated protein-like 4 3.8518
UNC13C unc-13 homolog C (C. elegans) 3.8518
PTH2 parathyroid hormone 2 3.8518
TMEM150B transmembrane protein 150B 3.8518
ART1 ADP-ribosyltransferase 1 3.8518
GOLGA8R golgin A8 family, member R 3.8518
GALR3 galanin receptor 3 3.74579
HORMAD1 HORMA domain containing 1 3.74579
TSGA13 testis specific, 13 3.74579
MAGEA8 melanoma antigen family A8 3.74579
FABP1 fatty acid binding protein 1, liver 3.74579
NXPH4 neurexophilin 4 3.74579
TMEM176A transmembrane protein 176A 3.74579
CD1C CD1c molecule 3.74579
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.74579
LY86 lymphocyte antigen 86 3.74579
TMEM212 transmembrane protein 212 3.74579
CCDC116 coiled-coil domain containing 116 3.74579
SRL sarcalumenin 3.74579
USH1G Usher syndrome 1G (autosomal recessive) 3.74579
TBX20 T-box 20 3.74579
PCDHGB3 protocadherin gamma subfamily B, 3 3.74579
SPDYE4 speedy/RINGO cell cycle regulator family member E4 3.74579
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 3.74579
TAS2R10 taste receptor, type 2, member 10 3.74579
GNRHR gonadotropin-releasing hormone receptor 3.74579
FABP12 fatty acid binding protein 12 3.74579
UMODL1 uromodulin-like 1 3.74579
TRIM7 tripartite motif containing 7 3.74579
C9ORF152 chromosome 9 open reading frame 152 3.74579
POSTN periostin, osteoblast specific factor 3.74579
CA1 carbonic anhydrase I 3.74579
GIMAP1 GTPase, IMAP family member 1 3.74579
OLFM4 olfactomedin 4 3.74579
WNT10B wingless-type MMTV integration site family, member 10B 3.74579
PLA2G5 phospholipase A2, group V 3.74579
DSG3 desmoglein 3 3.74579
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 3.74579
AADACL4 arylacetamide deacetylase-like 4 3.74579
OR2A1 olfactory receptor, family 2, subfamily A, member 1 3.74579
LIPC lipase, hepatic 3.74579
SCRG1 stimulator of chondrogenesis 1 3.74579
C1QTNF9B C1q and tumor necrosis factor related protein 9B 3.74579
FMO2 flavin containing monooxygenase 2 (non-functional) 3.74579
TMIGD1 transmembrane and immunoglobulin domain containing 1 3.74579
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase 3.74579
SIM1 single-minded family bHLH transcription factor 1 3.74579
GPX6 glutathione peroxidase 6 3.74579
H1-6 H1.6 linker histone, cluster member 3.74579
CFAP157 cilia and flagella associated protein 157 3.74579
FREY1 Frey regulator of sperm-oocyte fusion 1 3.74579
CCDC197 coiled-coil domain containing 197 3.74579
NHERF4 NHERF family PDZ scaffold protein 4 3.74579
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 3.74579
LINC02268 long intergenic non-protein coding RNA 2268 3.74579
WASH8P WAS protein family homolog 8, pseudogene 3.74579
OR56B2 olfactory receptor family 56 subfamily B member 2 3.74579
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 3.74579
MIOX myo-inositol oxygenase 3.74579
DAO D-amino-acid oxidase 3.74579
OR2J1 olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene) 3.74579
CATSPER3 cation channel, sperm associated 3 3.74579
MSX1 msh homeobox 1 3.74579
GOLGA8N golgin A8 family, member N 3.74579
TLR4 toll-like receptor 4 3.74579
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.74579
MIA melanoma inhibitory activity 3.74579
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 3.74579
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 3.74579
CLDN22 claudin 22 3.74579
CNTFR ciliary neurotrophic factor receptor 3.74579
FRK fyn-related Src family tyrosine kinase 3.74579
CCDC42 coiled-coil domain containing 42 3.74579
TBX10 T-box 10 3.74579
LOC107986837 uncharacterized LOC107986837 3.74579
POTEE POTE ankyrin domain family, member E 3.74579
LRRC31 leucine rich repeat containing 31 3.74579
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 3.74579
CTSS cathepsin S 3.74579
IFITM10 interferon induced transmembrane protein 10 3.74579
CNTF ciliary neurotrophic factor 3.74579
ZNF703 zinc finger protein 703 3.74579
IFITM5 interferon induced transmembrane protein 5 3.74579
CD84 CD84 molecule 3.74579
SH2D1B SH2 domain containing 1B 3.74579
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 3.74579
ASCL1 achaete-scute family bHLH transcription factor 1 3.74579
CIB3 calcium and integrin binding family member 3 3.74579
IL10RA interleukin 10 receptor, alpha 3.74579
DBX2 developing brain homeobox 2 3.74579
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 3.74579
MT1A metallothionein 1A 3.74579
HHIPL2 HHIP-like 2 3.74579
OR11G2 olfactory receptor, family 11, subfamily G, member 2 3.74579
OR3A1 olfactory receptor, family 3, subfamily A, member 1 3.74579
CLEC7A C-type lectin domain family 7, member A 3.74579
AICDA activation-induced cytidine deaminase 3.74579
SLC51B solute carrier family 51, beta subunit 3.74579
RTN4RL1 reticulon 4 receptor-like 1 3.74579
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.74579
EBF3 early B-cell factor 3 3.74579
MAGEC3 melanoma antigen family C3 3.74579
NANOGNB NANOG neighbor homeobox 3.74579
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 3.74579
TRADD TNFRSF1A-associated via death domain 3.74579
WFDC1 WAP four-disulfide core domain 1 3.74579
RXRG retinoid X receptor, gamma 3.74579
GOLGA6A golgin A6 family, member A 3.74579
ETV2 ets variant 2 3.74579
RTP3 receptor (chemosensory) transporter protein 3 3.74579
PRR22 proline rich 22 3.74579
WDR87 WD repeat domain 87 3.74579
ZNF735 zinc finger protein 735 3.74579
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 3.74579
C2ORF78 chromosome 2 open reading frame 78 3.74579
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 3.74579
FATE1 fetal and adult testis expressed 1 3.74579
NWD1 NACHT and WD repeat domain containing 1 3.74579
CLEC2B C-type lectin domain family 2, member B 3.74579
NPC1L1 NPC1-like 1 3.74579
ISLR immunoglobulin superfamily containing leucine-rich repeat 3.74579
LCN1 lipocalin 1 3.74579
RNASE6 ribonuclease, RNase A family, k6 3.74579
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 3.66465
CAPS2 calcyphosine 2 3.37647
FHIT fragile histidine triad 3.32953
SELENOV selenoprotein V 3.25638
PROC protein C (inactivator of coagulation factors Va and VIIIa) 3.13251
CFLAR CASP8 and FADD-like apoptosis regulator 3.05454
SERGEF secretion regulating guanine nucleotide exchange factor 3.03409
NPM2 nucleophosmin/nucleoplasmin 2 3.0298
RARS1 arginyl-tRNA synthetase 1 2.96022
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 2.92392
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 2.85203
FRMPD3 FERM and PDZ domain containing 3 2.83706
RASL10A RAS-like, family 10, member A 2.76142
TP53BP1 tumor protein p53 binding protein 1 2.74584
POT1 protection of telomeres 1 2.7366
TUNAR TCL1 upstream neural differentiation-associated RNA 2.72127
TMEM161B transmembrane protein 161B 2.6872
MPHOSPH9 M-phase phosphoprotein 9 2.63423
FBXO22 F-box protein 22 2.61517
TMEM131L transmembrane 131 like 2.60866
CCDC17 coiled-coil domain containing 17 2.58835
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 2.58789
TGFBR3L transforming growth factor, beta receptor III-like 2.51031
PHGDH phosphoglycerate dehydrogenase 2.47095
COL11A1 collagen, type XI, alpha 1 2.46218
SNX16 sorting nexin 16 2.41131
MTX3 metaxin 3 2.40386
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.32247
SEPTIN10 septin 10 2.31809
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.31809
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2.31352
NOCT nocturnin 2.291
TSPAN19 tetraspanin 19 2.27703
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.27703
ZDHHC24 zinc finger, DHHC-type containing 24 2.26908
GCH1 GTP cyclohydrolase 1 2.26356
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 2.2444
IGFLR1 IGF-like family receptor 1 2.24356
PRELID2 PRELI domain containing 2 2.23002
HELZ2 helicase with zinc finger 2, transcriptional coactivator 2.23002
CD72 CD72 molecule 2.20104
SBNO1 strawberry notch homolog 1 (Drosophila) 2.20104
SEC63 SEC63 homolog (S. cerevisiae) 2.19637
DRC1 dynein regulatory complex subunit 1 2.19151
CDCP2 CUB domain containing protein 2 2.19151
CDH26 cadherin 26 2.17647
NRXN3 neurexin 3 2.16815
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.15968
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 2.15813
TMEM220 transmembrane protein 220 2.15413
NKAIN3 Na+/K+ transporting ATPase interacting 3 2.14232
ZSWIM7 zinc finger, SWIM-type containing 7 2.08653
ZC2HC1A zinc finger, C2HC-type containing 1A 2.06863
SYTL3 synaptotagmin-like 3 2.06274
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 2.06274
CPEB2 cytoplasmic polyadenylation element binding protein 2 2.06247
POLH polymerase (DNA directed), eta 2.05724
KIFAP3 kinesin-associated protein 3 2.02704

decreased expression

Symbol Name Standardized Value
HSPB2 heat shock 27kDa protein 2 -3.8518
GOLGA6L7 golgin A6 family like 7 -3.8518
PRB3 proline-rich protein BstNI subfamily 3 -3.8518
NUDT4B nudix hydrolase 4B -3.74579
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 -3.74579
PCDHGA11 protocadherin gamma subfamily A, 11 -3.74579
BTBD16 BTB (POZ) domain containing 16 -3.74579
VPREB3 pre-B lymphocyte 3 -3.74579
ASCL3 achaete-scute family bHLH transcription factor 3 -3.74579
RP1 retinitis pigmentosa 1 (autosomal dominant) -3.74579
NUTM2G NUT family member 2G -3.74579
SUN3 Sad1 and UNC84 domain containing 3 -3.74579
PRAM1 PML-RARA regulated adaptor molecule 1 -3.74579
S100A2 S100 calcium binding protein A2 -3.74579
SH2D5 SH2 domain containing 5 -3.74579
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 -3.74579
TMEM225B transmembrane protein 225B -3.74579
MGAM maltase-glucoamylase -3.74579
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -3.74579
PRDM7 PR domain containing 7 -3.74579
ADGRG1 adhesion G protein-coupled receptor G1 -3.74579
CIMAP2 ciliary microtubule associated protein 2 -3.74579
HLF hepatic leukemia factor -3.74579
CD274 CD274 molecule -3.74579
LIPH lipase, member H -3.74579
CD200R1L CD200 receptor 1-like -3.74579
TMEM132D transmembrane protein 132D -3.74579
MR1 major histocompatibility complex, class I-related -3.74579
LMX1B LIM homeobox transcription factor 1, beta -3.74579
AKNAD1 AKNA domain containing 1 -3.74579
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 -3.74579
LDLRAD2 low density lipoprotein receptor class A domain containing 2 -3.74579
HCRT hypocretin (orexin) neuropeptide precursor -3.74579
PLN phospholamban -3.74579
ANKRD53 ankyrin repeat domain 53 -3.74579
PABPN1 poly(A) binding protein, nuclear 1 -2.99922
ZBTB8B zinc finger and BTB domain containing 8B -2.98791
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -2.97074
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 -2.94655
ARL3 ADP-ribosylation factor-like 3 -2.94138
RPSA ribosomal protein SA -2.93407
RBM12B RNA binding motif protein 12B -2.8468
FGF23 fibroblast growth factor 23 -2.83508
GPR146 G protein-coupled receptor 146 -2.79007
ZNF564 zinc finger protein 564 -2.78362
GTPBP10 GTP-binding protein 10 (putative) -2.76216
CLEC11A C-type lectin domain family 11, member A -2.7315
H3-3A H3.3 histone A -2.59105
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 -2.56287
ATP5MC2 ATP synthase membrane subunit c locus 2 -2.54072
ANKRD29 ankyrin repeat domain 29 -2.53089
SCML1 sex comb on midleg-like 1 (Drosophila) -2.52459
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -2.41131
RPS28 ribosomal protein S28 -2.3618
NDUFAF8 NADH:ubiquinone oxidoreductase complex assembly factor 8 -2.3584
SRFBP1 serum response factor binding protein 1 -2.35594
IFI35 interferon-induced protein 35 -2.34654
FNDC11 fibronectin type III domain containing 11 -2.34654
MYT1L myelin transcription factor 1-like -2.34654
SERF1B small EDRK-rich factor 1B (centromeric) -2.34654
LRRC19 leucine rich repeat containing 19 -2.34654
RSPO4 R-spondin 4 -2.34654
TMC3 transmembrane channel-like 3 -2.34654
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -2.31809
OXCT2 3-oxoacid CoA transferase 2 -2.31809
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -2.31809
KBTBD12 kelch repeat and BTB (POZ) domain containing 12 -2.31809
CIRBP cold inducible RNA binding protein -2.31809
IQCN IQ motif containing N -2.31809
WDR76 WD repeat domain 76 -2.29116
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.26356
SEZ6 seizure related 6 homolog (mouse) -2.26227
ATP5F1B ATP synthase F1 subunit beta -2.26227
ANKRD34B ankyrin repeat domain 34B -2.23606
MLIP muscular LMNA-interacting protein -2.21544
PANO1 proapoptotic nucleolar protein 1 -2.21544
IL11 interleukin 11 -2.21544
MINDY2 MINDY lysine 48 deubiquitinase 2 -2.18586
TNPO1 transportin 1 -2.17651
TXNDC11 thioredoxin domain containing 11 -2.17369
TXNIP thioredoxin interacting protein -2.15968
MT2A metallothionein 2A -2.15813
SCYL1 SCY1-like 1 (S. cerevisiae) -2.15403
PILRA paired immunoglobin-like type 2 receptor alpha -2.15395
CAMKV CaM kinase-like vesicle-associated -2.15395
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.15395
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) -2.1441
ATF6B activating transcription factor 6 beta -2.13705
CCDC97 coiled-coil domain containing 97 -2.13432
EFCAB10 EF-hand calcium binding domain 10 -2.10755
EXD3 exonuclease 3'-5' domain containing 3 -2.10585
ELP3 elongator acetyltransferase complex subunit 3 -2.10029
BAK1 BCL2-antagonist/killer 1 -2.06863
ZNFX1 zinc finger, NFX1-type containing 1 -2.06863
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -2.06863
SMOC2 SPARC related modular calcium binding 2 -2.06863
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 -2.05731
PDAP1 PDGFA associated protein 1 -2.01945
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.01459
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -2.0084
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.00787
MFF mitochondrial fission factor -2.00659
FTL ferritin, light polypeptide -2.00659
IFT43 intraflagellar transport 43 -2.00079