MAFK Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K|The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008] (NCBI Entrez Gene Database, 7975)
External Link http://www.ncbi.nlm.nih.gov/gene/7975
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Genes

36 interacting proteins for MAFK from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ARF1 ADP-ribosylation factor 1
ARF3 ADP-ribosylation factor 3
ATF7 activating transcription factor 7
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CREB3 cAMP responsive element binding protein 3
CREB5 cAMP responsive element binding protein 5
CREBBP CREB binding protein
DDIT3 DNA-damage-inducible transcript 3
DYNLL1 dynein, light chain, LC8-type 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXD12 homeobox D12
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KAT6A K(lysine) acetyltransferase 6A
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MARS methionyl-tRNA synthetase
NFE2 nuclear factor, erythroid 2
NFE2L1 nuclear factor, erythroid 2-like 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFE2L3 nuclear factor, erythroid 2-like 3
PARP1 poly (ADP-ribose) polymerase 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SACK1D scaffolding CK1 anchoring protein D
SMAD3 SMAD family member 3
SUMO2 small ubiquitin-like modifier 2
TP53 tumor protein p53
UBC ubiquitin C