MAGEA8 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description melanoma antigen family A8|This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 4107)
External Link http://www.ncbi.nlm.nih.gov/gene/4107
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Genes

2 interacting proteins for MAGEA8 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
UBC ubiquitin C
UBE3A ubiquitin protein ligase E3A