MAGI2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description membrane associated guanylate kinase, WW and PDZ domain containing 2|The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9863)
External Link https://ncbi.nlm.nih.gov/gene/9863
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Genes

499 genes differentially expressed following the MAGI2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 0.0172357
CSTA cystatin A (stefin A) 0.0151749
S100A7 S100 calcium binding protein A7 0.0151088
RGCC regulator of cell cycle 0.0149135
CRABP2 cellular retinoic acid binding protein 2 0.0147094
SPRR3 small proline-rich protein 3 0.0136585
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0134558
S100A14 S100 calcium binding protein A14 0.0132956
KRT14 keratin 14, type I 0.0132045
KRT5 keratin 5, type II 0.0131621
SCGB2A1 secretoglobin, family 2A, member 1 0.0130736
KRT6A keratin 6A, type II 0.0130267
FABP7 fatty acid binding protein 7, brain 0.0127508
CA2 carbonic anhydrase II 0.0124468
KRT15 keratin 15, type I 0.012381
SLPI secretory leukocyte peptidase inhibitor 0.0122908
CLCA4 chloride channel accessory 4 0.0120389
ACTA2 actin, alpha 2, smooth muscle, aorta 0.0118674
KRT13 keratin 13, type I 0.0118378
S100A8 S100 calcium binding protein A8 0.0117011
S100A9 S100 calcium binding protein A9 0.0115897
IFI27 interferon, alpha-inducible protein 27 0.0114367
TRIM29 tripartite motif containing 29 0.0112124
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0110759
ANXA1 annexin A1 0.0110702
KYNU kynureninase 0.0110148
MED6 mediator complex subunit 6 0.0109921
XIC X chromosome inactivation center 0.0109806
FOLR1 folate receptor 1 (adult) 0.0107964
SPRR1B small proline-rich protein 1B 0.0107803
MAP7 microtubule-associated protein 7 0.0105302
AQP3 aquaporin 3 (Gill blood group) 0.0104937
KRT17 keratin 17, type I 0.0104781
PI3 peptidase inhibitor 3, skin-derived 0.0103479
DAZAP2 DAZ associated protein 2 0.0103163
PODXL podocalyxin-like 0.0102761
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.01013
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.010064
HLA-B major histocompatibility complex, class I, B 0.010011
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00986763
SSBP2 single-stranded DNA binding protein 2 0.00974119
TPM4 tropomyosin 4 0.00972413
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.0096069
EXOC5 exocyst complex component 5 0.00956654
MCL1 myeloid cell leukemia 1 0.00953938
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00939749
YIPF5 Yip1 domain family, member 5 0.00938199
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00930789
GUCY2C guanylate cyclase 2C 0.00927901
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00927704
CLDN8 claudin 8 0.00922696
ATG5 autophagy related 5 0.00904265
LYPD3 LY6/PLAUR domain containing 3 0.00903944
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0090111
ABLIM1 actin binding LIM protein 1 0.00898565
HIST1H2AC histone cluster 1, H2ac 0.0089762
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00892069
PEG3 paternally expressed 3 0.00889627
SH3YL1 SH3 and SYLF domain containing 1 0.00886846
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00883374
TAGLN2 transgelin 2 0.00881077
NEBL nebulette 0.00877795
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00873596
LAMP3 lysosomal-associated membrane protein 3 0.00870899
RSL1D1 ribosomal L1 domain containing 1 0.00870111
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00868773
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00867278
NMD3 NMD3 ribosome export adaptor 0.00865097
TNNT1 troponin T type 1 (skeletal, slow) 0.00859392
SELENOT selenoprotein T 0.00857581
KRT6B keratin 6B, type II 0.00850037
CD59 CD59 molecule, complement regulatory protein 0.00848019
CAST calpastatin 0.00842222
MAL mal, T-cell differentiation protein 0.00837161
PERP PERP, TP53 apoptosis effector 0.00836656
RAB1A RAB1A, member RAS oncogene family 0.00835832
TACSTD2 tumor-associated calcium signal transducer 2 0.00832961
RHCG Rh family, C glycoprotein 0.00829836
FXYD3 FXYD domain containing ion transport regulator 3 0.00829543
CLCA2 chloride channel accessory 2 0.00828015
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00827939
KRT16 keratin 16, type I 0.00827095
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00826162
KRT19 keratin 19, type I 0.00825565
CLDN7 claudin 7 0.00822254
TNNC1 troponin C type 1 (slow) 0.00821879
KLF6 Kruppel-like factor 6 0.00818492
MYBPC1 myosin binding protein C, slow type 0.00817918
WDR7 WD repeat domain 7 0.00817486
IL10RB interleukin 10 receptor, beta 0.00814458
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00813895
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00811457
TTN titin 0.0081025
ELL2 elongation factor, RNA polymerase II, 2 0.00807517
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00806448
DEFB1 defensin, beta 1 0.00803842
SGK1 serum/glucocorticoid regulated kinase 1 0.00802555
EMX2 empty spiracles homeobox 2 0.00798484
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00796166
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00795665
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00794071
NFYA nuclear transcription factor Y, alpha 0.00793573
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00791954
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00791843
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00791269
IRF6 interferon regulatory factor 6 0.0078778
CLTB clathrin, light chain B 0.00787541
FGFBP1 fibroblast growth factor binding protein 1 0.00786764
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00783708
SPRR1A small proline-rich protein 1A 0.00781602
DENND1B DENN/MADD domain containing 1B 0.00781108
ABHD17B abhydrolase domain containing 17B 0.00779739
PITX1 paired-like homeodomain 1 0.00778213
GDI2 GDP dissociation inhibitor 2 0.0077741
CANX calnexin 0.00776023
POSTN periostin, osteoblast specific factor 0.0077529
XPO7 exportin 7 0.00773753
TMEM45A transmembrane protein 45A 0.0077329
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00771423
ADAM10 ADAM metallopeptidase domain 10 0.00771168
GNAS GNAS complex locus 0.00770453
ACTA1 actin, alpha 1, skeletal muscle 0.00765836
PDE4B phosphodiesterase 4B, cAMP-specific 0.00764318
CLDN10 claudin 10 0.00763494
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00761424
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00758873
CDK14 cyclin-dependent kinase 14 0.00757411
LY6D lymphocyte antigen 6 complex, locus D 0.00751883
DSG3 desmoglein 3 0.00750379
GAP43 growth associated protein 43 0.00749282
AGPS alkylglycerone phosphate synthase 0.00747622
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.0074578
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00744727
ISG20 interferon stimulated exonuclease gene 20kDa 0.00744704
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00742122
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.00740313
FAM198B family with sequence similarity 198, member B 0.00736071
LITAF lipopolysaccharide-induced TNF factor 0.00735572
PLIN3 perilipin 3 0.00735092
IFI16 interferon, gamma-inducible protein 16 0.00732528
COG5 component of oligomeric golgi complex 5 0.00727904
CEMIP cell migration inducing protein, hyaluronan binding 0.00725632
LMAN1 lectin, mannose-binding, 1 0.0072352
MDH1 malate dehydrogenase 1, NAD (soluble) 0.00722402
SPRED2 sprouty-related, EVH1 domain containing 2 0.00712149
LYRM2 LYR motif containing 2 0.00708401
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.0070757
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.007063
ADM adrenomedullin 0.00704679
NDFIP1 Nedd4 family interacting protein 1 0.00704266
MB myoglobin 0.0070395
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.00703898
MMP10 matrix metallopeptidase 10 0.00701981
IFNGR1 interferon gamma receptor 1 0.00701845
STATH statherin 0.00700821
ZFYVE21 zinc finger, FYVE domain containing 21 0.00699067
TMOD3 tropomodulin 3 (ubiquitous) 0.00698546
GRB7 growth factor receptor-bound protein 7 0.00694689
SRSF1 serine/arginine-rich splicing factor 1 0.00690591
ZNF277 zinc finger protein 277 0.0068936
ZFP36L2 ZFP36 ring finger protein-like 2 0.0068683
RAB25 RAB25, member RAS oncogene family 0.00685343
NEU1 sialidase 1 (lysosomal sialidase) 0.00685314
RPP14 ribonuclease P/MRP 14kDa subunit 0.00684256
OXA1L oxidase (cytochrome c) assembly 1-like 0.00684154
COMMD10 COMM domain containing 10 0.00682116
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00680291
RANBP9 RAN binding protein 9 0.00679071
FOXG1 forkhead box G1 0.00679009
SEPP1 selenoprotein P, plasma, 1 0.00678823
GDE1 glycerophosphodiester phosphodiesterase 1 0.00678288
HIST1H2BD histone cluster 1, H2bd 0.00674793
CHMP1B charged multivesicular body protein 1B 0.00674466
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.0067394
DAXX death-domain associated protein 0.00673255
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00670711
HLA-F major histocompatibility complex, class I, F 0.00666573
NOP10 NOP10 ribonucleoprotein 0.00665565
PDE8B phosphodiesterase 8B 0.0066544
LIMA1 LIM domain and actin binding 1 0.00665168
LY96 lymphocyte antigen 96 0.00664101
TSPAN6 tetraspanin 6 0.00661818
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.006618
VLDLR very low density lipoprotein receptor 0.00660341
NCK1 NCK adaptor protein 1 0.00659578
CD14 CD14 molecule 0.00659134
DCTN4 dynactin 4 (p62) 0.00658726
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00656479
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00653895
CCL14 chemokine (C-C motif) ligand 14 0.0065192
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.0065122
ISG15 ISG15 ubiquitin-like modifier 0.00651205
CFAP20 cilia and flagella associated protein 20 0.00649491
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00644961
BCAS1 breast carcinoma amplified sequence 1 0.00643145
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 0.00641223
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00640043
KLF4 Kruppel-like factor 4 (gut) 0.00639052
CALML3 calmodulin-like 3 0.00637505
YPEL5 yippee-like 5 (Drosophila) 0.00636118
RBBP4 retinoblastoma binding protein 4 0.0063503
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00634248
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00633967
PEA15 phosphoprotein enriched in astrocytes 15 0.00633686
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00633192
RAB5C RAB5C, member RAS oncogene family 0.0063274
GRAMD2B GRAM domain containing 2B 0.00632473
IFI44L interferon-induced protein 44-like 0.0063182
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00631461
CLEC2B C-type lectin domain family 2, member B 0.00630228
GSN gelsolin 0.00629202
ATG12 autophagy related 12 0.00629066
KRT81 keratin 81, type II 0.0062889
FMO1 flavin containing monooxygenase 1 0.00628226
RCAN1 regulator of calcineurin 1 0.00628021
CHGB chromogranin B 0.00626258
MEN1 multiple endocrine neoplasia I 0.00625991
TCTA T-cell leukemia translocation altered 0.00624223
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00623631
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 0.00623265
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.00622707
SAMD9 sterile alpha motif domain containing 9 0.00622269
RDX radixin 0.00622024
COQ8A coenzyme Q8A 0.00621071
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00620751
FKBP1A FK506 binding protein 1A, 12kDa 0.00620581
MT1F metallothionein 1F 0.00620397
ESRP1 epithelial splicing regulatory protein 1 0.00619072
CRYAB crystallin, alpha B 0.00618746
VAMP8 vesicle-associated membrane protein 8 0.00617893
CD164 CD164 molecule, sialomucin 0.0061785
DIO1 deiodinase, iodothyronine, type I 0.00617368
PLSCR1 phospholipid scramblase 1 0.00617125
YBX3 Y box binding protein 3 0.00613429
MYOF myoferlin 0.00612984
R3HCC1L R3H domain and coiled-coil containing 1-like 0.00612828
KLK5 kallikrein-related peptidase 5 0.00612708
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.00612591
B2M beta-2-microglobulin 0.00611883
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.00611493
ETHE1 ethylmalonic encephalopathy 1 0.00610812
ANXA2P2 annexin A2 pseudogene 2 0.00607415
RNF14 ring finger protein 14 0.00606718
SLN sarcolipin 0.00606345
EMC2 ER membrane protein complex subunit 2 0.00605765
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.00604425
ARHGAP32 Rho GTPase activating protein 32 0.00603904
CHEK1 checkpoint kinase 1 0.00603837
PTHLH parathyroid hormone-like hormone 0.00602627
HNMT histamine N-methyltransferase 0.00602449

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0226336
ZBTB18 zinc finger and BTB domain containing 18 -0.0179109
CD320 CD320 molecule -0.0158279
TPSAB1 tryptase alpha/beta 1 -0.0140342
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0135981
PLAAT3 phospholipase A and acyltransferase 3 -0.0132327
AGR2 anterior gradient 2 -0.0127686
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.0124801
DACH1 dachshund family transcription factor 1 -0.0123625
FBLN1 fibulin 1 -0.0123269
CLGN calmegin -0.0114912
COMP cartilage oligomeric matrix protein -0.0114454
KDM5D lysine (K)-specific demethylase 5D -0.0114074
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.0113137
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.0110712
ZBTB20 zinc finger and BTB domain containing 20 -0.0109213
OLFM4 olfactomedin 4 -0.0105732
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0105447
IL7R interleukin 7 receptor -0.0105346
PLIN2 perilipin 2 -0.0104773
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.0103886
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.0103349
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0102483
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.0102388
COL14A1 collagen, type XIV, alpha 1 -0.0102055
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.0102055
LTBP2 latent transforming growth factor beta binding protein 2 -0.0101216
PLA1A phospholipase A1 member A -0.0100901
SLIT2 slit homolog 2 (Drosophila) -0.00996648
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00971401
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00965291
EFNB2 ephrin-B2 -0.00964072
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00963619
ELOVL5 ELOVL fatty acid elongase 5 -0.00952647
AXL AXL receptor tyrosine kinase -0.00943848
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00939478
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.0090963
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00899977
BMP4 bone morphogenetic protein 4 -0.00898215
GPX2 glutathione peroxidase 2 -0.00895642
KANK2 KN motif and ankyrin repeat domains 2 -0.00895191
FASN fatty acid synthase -0.00894634
NID2 nidogen 2 (osteonidogen) -0.00883882
FADS1 fatty acid desaturase 1 -0.00883532
SORBS1 sorbin and SH3 domain containing 1 -0.00876217
SPON2 spondin 2, extracellular matrix protein -0.00871223
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00867002
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00860915
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00847449
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00844013
REG3A regenerating islet-derived 3 alpha -0.00838333
IGFBP1 insulin-like growth factor binding protein 1 -0.00827383
EML3 echinoderm microtubule associated protein like 3 -0.00826939
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.00819195
DVL1 dishevelled segment polarity protein 1 -0.00814954
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0080804
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00803646
ACADVL acyl-CoA dehydrogenase, very long chain -0.00801929
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.00797909
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00787511
MDK midkine (neurite growth-promoting factor 2) -0.00786598
EFHD2 EF-hand domain family, member D2 -0.00781519
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0077689
KANK1 KN motif and ankyrin repeat domains 1 -0.00773962
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00769991
TMX4 thioredoxin-related transmembrane protein 4 -0.00769542
DGKZ diacylglycerol kinase, zeta -0.00766952
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00765855
FGFR1 fibroblast growth factor receptor 1 -0.00765536
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00764355
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00763661
PRKCSH protein kinase C substrate 80K-H -0.00763521
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00759852
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00759591
MPRIP myosin phosphatase Rho interacting protein -0.00757609
ARHGAP29 Rho GTPase activating protein 29 -0.00756316
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00752693
PCP4 Purkinje cell protein 4 -0.00749672
MET MET proto-oncogene, receptor tyrosine kinase -0.00748275
RBPMS RNA binding protein with multiple splicing -0.00747612
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00747534
TGFBI transforming growth factor, beta-induced, 68kDa -0.00745236
PRKCZ protein kinase C, zeta -0.00744305
C1R complement component 1, r subcomponent -0.00744028
INTS1 integrator complex subunit 1 -0.00743456
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00742689
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00740741
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00739467
MTCL1 microtubule crosslinking factor 1 -0.00732237
REG1A regenerating islet-derived 1 alpha -0.00728962
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00728273
ELN elastin -0.00727647
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00726563
RRAGA Ras-related GTP binding A -0.00725961
TOX3 TOX high mobility group box family member 3 -0.00725166
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00723342
EPHB2 EPH receptor B2 -0.00722584
GREM1 gremlin 1, DAN family BMP antagonist -0.00720329
SACS sacsin molecular chaperone -0.00720124
TXLNA taxilin alpha -0.00718911
REC8 REC8 meiotic recombination protein -0.00715645
FBLN2 fibulin 2 -0.00715511
RAPSN receptor-associated protein of the synapse -0.00714643
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00713288
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.00712833
WTAP Wilms tumor 1 associated protein -0.00709703
KIF18B kinesin family member 18B -0.00708151
TNC tenascin C -0.00707829
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00707476
PNKP polynucleotide kinase 3'-phosphatase -0.00707245
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00702118
CCNF cyclin F -0.00692986
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.00692869
GUSB glucuronidase, beta -0.00684617
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00683749
AEBP1 AE binding protein 1 -0.00681735
APMAP adipocyte plasma membrane associated protein -0.00679093
STK25 serine/threonine kinase 25 -0.00678657
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00676243
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00675691
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.00675658
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00674746
CST3 cystatin C -0.00674607
GEM GTP binding protein overexpressed in skeletal muscle -0.00672127
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00671799
LCN2 lipocalin 2 -0.00671296
TSPYL5 TSPY-like 5 -0.00670681
TWIST1 twist family bHLH transcription factor 1 -0.00668778
TBL1X transducin (beta)-like 1X-linked -0.00665074
SMTN smoothelin -0.0066283
JMJD6 jumonji domain containing 6 -0.00662481
CCL19 chemokine (C-C motif) ligand 19 -0.00662422
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00661195
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00661047
RNF43 ring finger protein 43 -0.00657929
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00655007
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00654749
TNIK TRAF2 and NCK interacting kinase -0.00654647
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00653281
ALOX5 arachidonate 5-lipoxygenase -0.00653268
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00651799
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00651758
ATP5ME ATP synthase membrane subunit e -0.00651739
NPY neuropeptide Y -0.00650592
CDK11A cyclin-dependent kinase 11A -0.00649813
MAN2C1 mannosidase, alpha, class 2C, member 1 -0.00649488
LEF1 lymphoid enhancer-binding factor 1 -0.00649278
SRRT serrate, RNA effector molecule -0.00647741
CEP170 centrosomal protein 170kDa -0.00646389
NAV2 neuron navigator 2 -0.00645916
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00643419
DYNLL1 dynein, light chain, LC8-type 1 -0.00643256
IPO9 importin 9 -0.00643084
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00642859
KLK2 kallikrein-related peptidase 2 -0.00641391
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00640803
PLEC plectin -0.00640251
SMAD7 SMAD family member 7 -0.00637992
MMD monocyte to macrophage differentiation-associated -0.00635929
MICALL2 MICAL-like 2 -0.0063569
NNMT nicotinamide N-methyltransferase -0.00634245
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00634169
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -0.00630997
GMPR guanosine monophosphate reductase -0.00629664
NVL nuclear VCP-like -0.00628757
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00628534
BRCA1 breast cancer 1, early onset -0.00624662
CIDEA cell death-inducing DFFA-like effector a -0.00624084
SIDT2 SID1 transmembrane family, member 2 -0.00623697
MXRA5 matrix-remodelling associated 5 -0.00623028
PMP22 peripheral myelin protein 22 -0.00622217
MXRA8 matrix-remodelling associated 8 -0.00621644
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -0.00621447
SDC3 syndecan 3 -0.00620409
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.00619519
G0S2 G0/G1 switch 2 -0.00618689
CCDC92 coiled-coil domain containing 92 -0.00618612
TSPAN8 tetraspanin 8 -0.00618417
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00617992
SAFB2 scaffold attachment factor B2 -0.00616499
DCLK1 doublecortin-like kinase 1 -0.00615834
EMP3 epithelial membrane protein 3 -0.00614833
LMNA lamin A/C -0.00613123
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00612959
PYGB phosphorylase, glycogen; brain -0.00610941
PDZRN3 PDZ domain containing ring finger 3 -0.0061043
JCHAIN joining chain of multimeric IgA and IgM -0.00610186
FAM13A family with sequence similarity 13, member A -0.00609064
BANP BTG3 associated nuclear protein -0.00608921
MICU2 mitochondrial calcium uptake 2 -0.00608595
FOXF1 forkhead box F1 -0.00607825
ATG4B autophagy related 4B, cysteine peptidase -0.00605532
GLS glutaminase -0.00605531
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.00604987
PLIN1 perilipin 1 -0.006042
GGCT gamma-glutamylcyclotransferase -0.00601761
CHRDL1 chordin-like 1 -0.00600268
MYO5C myosin VC -0.00598955
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00596748
TFF3 trefoil factor 3 (intestinal) -0.00595719
PRRC2A proline-rich coiled-coil 2A -0.00595361
CPB1 carboxypeptidase B1 (tissue) -0.00594419
PNPLA6 patatin-like phospholipase domain containing 6 -0.00594314
APOC1 apolipoprotein C-I -0.00593875
MYH11 myosin, heavy chain 11, smooth muscle -0.00593485
CDC20 cell division cycle 20 -0.00592595
LBR lamin B receptor -0.00590526
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00590181
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00589486
ZNF423 zinc finger protein 423 -0.00589418
TRIM28 tripartite motif containing 28 -0.00588913
PLXNC1 plexin C1 -0.00588298
FBXW12 F-box and WD repeat domain containing 12 -0.00588258
SCD5 stearoyl-CoA desaturase 5 -0.00587791
PTPRD protein tyrosine phosphatase, receptor type, D -0.00587113
MPC2 mitochondrial pyruvate carrier 2 -0.00585201
ADAM9 ADAM metallopeptidase domain 9 -0.00584956
TM4SF4 transmembrane 4 L six family member 4 -0.0058418
TBX3 T-box 3 -0.00584128
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00582781
TNK2 tyrosine kinase, non-receptor, 2 -0.00580607
NRN1 neuritin 1 -0.00580333
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -0.00580095
TSC2 tuberous sclerosis 2 -0.00579027
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00577767
BRD4 bromodomain containing 4 -0.00576453
TGFB3 transforming growth factor, beta 3 -0.00575603
TBCD tubulin folding cofactor D -0.00574153
PILRB paired immunoglobin-like type 2 receptor beta -0.0057333
CCNL2 cyclin L2 -0.00573263
COL16A1 collagen, type XVI, alpha 1 -0.00572432
LACTB2 lactamase, beta 2 -0.00570031
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -0.00569522
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -0.00569049
DENND4B DENN/MADD domain containing 4B -0.00568781
AKAP12 A kinase (PRKA) anchor protein 12 -0.00568186
NOTCH2 notch 2 -0.00568172
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00567462
THAP12 THAP domain containing 12 -0.00567116
BGN biglycan -0.00566801
DAPK1 death-associated protein kinase 1 -0.00564597
MFSD10 major facilitator superfamily domain containing 10 -0.00564459
TBC1D16 TBC1 domain family, member 16 -0.0056432
BICC1 BicC family RNA binding protein 1 -0.00563803
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.00561633
INSIG1 insulin induced gene 1 -0.00561077
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00560995
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00560567
PHLDB1 pleckstrin homology-like domain, family B, member 1 -0.00560524