MAN2C1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mannosidase, alpha, class 2C, member 1| (NCBI Entrez Gene Database, 4123)
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Genes

338 genes differentially expressed following the MAN2C1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CFHR5 complement factor H-related 5 2.49433
FGL1 fibrinogen-like 1 2.49433
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.49433
UNC13C unc-13 homolog C (C. elegans) 2.49433
ABHD16B abhydrolase domain containing 16B 2.49433
NCF1 neutrophil cytosolic factor 1 2.49433
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.49433
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.49433
IL5RA interleukin 5 receptor, alpha 2.49433
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.49433
ARHGAP36 Rho GTPase activating protein 36 2.49433
FGL2 fibrinogen-like 2 2.49433
TEX13B testis expressed 13B 2.49433
SPATA31A6 SPATA31 subfamily A, member 6 2.49433
LURAP1L leucine rich adaptor protein 1-like 2.49433
ALB albumin 2.49433
NAPSA napsin A aspartic peptidase 2.49433
CEMP1 cementum protein 1 2.49433
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.49433
GPR55 G protein-coupled receptor 55 2.49433
POM121C POM121 transmembrane nucleoporin C 2.49433
SLC26A9 solute carrier family 26 (anion exchanger), member 9 2.49433
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.49433
CD19 CD19 molecule 2.49433
TLX3 T-cell leukemia homeobox 3 2.49433
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.49433
BFSP2 beaded filament structural protein 2, phakinin 2.49433
ATOH7 atonal homolog 7 (Drosophila) 2.49433
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.49433
TBC1D3 TBC1 domain family, member 3 2.49433
MRC1 mannose receptor, C type 1 2.49433
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.49433
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.49433
NMUR2 neuromedin U receptor 2 2.49433
SPAG8 sperm associated antigen 8 2.49433
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.49433
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 2.49433
S100A1 S100 calcium binding protein A1 2.49433
LRRIQ4 leucine-rich repeats and IQ motif containing 4 2.49433
CIITA class II, major histocompatibility complex, transactivator 2.49433
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.49433
SHCBP1L SHC SH2-domain binding protein 1-like 2.49433
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.49433
FHL5 four and a half LIM domains 5 2.49433
C16ORF82 chromosome 16 open reading frame 82 2.49433
ARSI arylsulfatase family, member I 2.49433
GADL1 glutamate decarboxylase-like 1 2.49433
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.49433
LGI1 leucine-rich, glioma inactivated 1 2.49433
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 2.49433
VCF1 VCP nuclear cofactor family member 1 2.49433
MALRD1 MAM and LDL receptor class A domain containing 1 2.49433
PLCZ1 phospholipase C, zeta 1 2.49433
NEURL3 neuralized E3 ubiquitin protein ligase 3 2.49433
TMEM196 transmembrane protein 196 2.49433
RAB36 RAB36, member RAS oncogene family 2.49433
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.49433
GATA3 GATA binding protein 3 2.49433
KL klotho 2.49433
PRG4 proteoglycan 4 2.49433
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 2.49433
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase 2.49433
C3AR1 complement component 3a receptor 1 2.49433
GBP6 guanylate binding protein family, member 6 2.49433
TEKTL1 tektin like 1 2.49433
LITAFD LITAF domain containing 2.49433
CIBAR2 CBY1 interacting BAR domain containing 2 2.49433
CLEC20A C-type lectin domain containing 20A 2.49433
GASK1B golgi associated kinase 1B 2.49433
GMCL2 germ cell-less 2, spermatogenesis associated 2.49433
INTS14 integrator complex subunit 14 2.49433
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.49433
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 2.49433
MT4 metallothionein 4 2.49433
LRRC73 leucine rich repeat containing 73 2.49433
PGLYRP2 peptidoglycan recognition protein 2 2.49433
PTPRC protein tyrosine phosphatase, receptor type, C 2.49433
KLHL33 kelch-like family member 33 2.49433
OR5H2 olfactory receptor, family 5, subfamily H, member 2 2.49433
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.49433
HDC histidine decarboxylase 2.49433
IL36G interleukin 36, gamma 2.49433
OR2A1 olfactory receptor, family 2, subfamily A, member 1 2.49433
CPNE6 copine VI (neuronal) 2.49433
ACR acrosin 2.49433
GPR4 G protein-coupled receptor 4 2.49433
AMY1C amylase, alpha 1C (salivary) 2.49433
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.49433
GAST gastrin 2.49433
TACR2 tachykinin receptor 2 2.49433
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.49433
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.49433
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.49433
IFNL2 interferon, lambda 2 2.49433
C1QTNF8 C1q and tumor necrosis factor related protein 8 2.49433
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 2.49433
RNF113B ring finger protein 113B 2.49433
SYVN1 synovial apoptosis inhibitor 1, synoviolin 2.49433
OR8D4 olfactory receptor, family 8, subfamily D, member 4 2.49433
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.49433
CATIP ciliogenesis associated TTC17 interacting protein 2.49433
SLC38A3 solute carrier family 38, member 3 2.49433
PCDHGB2 protocadherin gamma subfamily B, 2 2.49433
PDPR pyruvate dehydrogenase phosphatase regulatory subunit 2.49433
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.49433
RGS13 regulator of G-protein signaling 13 2.49433
LRTM2 leucine-rich repeats and transmembrane domains 2 2.49433
ACSBG1 acyl-CoA synthetase bubblegum family member 1 2.49433
FGR FGR proto-oncogene, Src family tyrosine kinase 2.49433
DES desmin 2.49433
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.49433
ACKR3 atypical chemokine receptor 3 2.49433
LPAR5 lysophosphatidic acid receptor 5 2.49433
OR13A1 olfactory receptor, family 13, subfamily A, member 1 2.49433
APOD apolipoprotein D 2.49433
LHX2 LIM homeobox 2 2.49433
PRSS54 protease, serine, 54 2.49433
TAT tyrosine aminotransferase 2.49433
ABHD17C abhydrolase domain containing 17C 2.49433
CPSF4L cleavage and polyadenylation specific factor 4-like 2.49433
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.49433
FSHR follicle stimulating hormone receptor 2.49433
SIRPG signal-regulatory protein gamma 2.49433
VWA7 von Willebrand factor A domain containing 7 2.49433
FBXL22 F-box and leucine-rich repeat protein 22 2.49433
DNTT DNA nucleotidylexotransferase 2.49433
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.49433
HRCT1 histidine rich carboxyl terminus 1 2.49433
KIAA1210 KIAA1210 2.49433
NGB neuroglobin 2.49433
TRIM55 tripartite motif containing 55 2.49433
SMIM23 small integral membrane protein 23 2.49433
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.49433
KLF1 Kruppel-like factor 1 (erythroid) 2.49433
HAVCR1 hepatitis A virus cellular receptor 1 2.49433
MTIF2 mitochondrial translational initiation factor 2 2.49433
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.49433
CPA4 carboxypeptidase A4 2.49433
MAB21L3 mab-21-like 3 (C. elegans) 2.49433
FAM25G family with sequence similarity 25, member G 2.49433
FCAR Fc fragment of IgA receptor 2.49433
GREM1 gremlin 1, DAN family BMP antagonist 2.49433
TTC36 tetratricopeptide repeat domain 36 2.49433
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.49433
CIB3 calcium and integrin binding family member 3 2.49433
DMRTC1 DMRT-like family C1 2.49433
TMEM156 transmembrane protein 156 2.49433
GPATCH2 G patch domain containing 2 2.49433
SNTN sentan, cilia apical structure protein 2.49433
PUS7 pseudouridylate synthase 7 (putative) 2.49433
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.49433
NPR3 natriuretic peptide receptor 3 2.49433
TMEM52B transmembrane protein 52B 2.49433
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.49433
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 2.49433
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 2.49433
OR4M2 olfactory receptor, family 4, subfamily M, member 2 2.49433
GPR179 G protein-coupled receptor 179 2.49433
AHSG alpha-2-HS-glycoprotein 2.49433
TUBAL3 tubulin, alpha-like 3 2.49433
PCDHAC2 protocadherin alpha subfamily C, 2 2.49433
SPTA1 spectrin, alpha, erythrocytic 1 2.49433
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.49433
IGSF11 immunoglobulin superfamily, member 11 2.49433
ADGRF1 adhesion G protein-coupled receptor F1 2.49433
APOL5 apolipoprotein L, 5 2.49433
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.49433
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 2.49433
DEFB136 defensin, beta 136 2.49433
PAGE2B P antigen family, member 2B 2.49433
TRPM5 transient receptor potential cation channel, subfamily M, member 5 2.49433
TRIM7 tripartite motif containing 7 2.49433
PPP1R27 protein phosphatase 1, regulatory subunit 27 2.49433
PLA2G2C phospholipase A2, group IIC 2.49433
FREM3 FRAS1 related extracellular matrix 3 2.47387
PRSS53 protease, serine, 53 2.45203
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 2.45203
CFAP100 cilia and flagella associated protein 100 2.45203
MIXL1 Mix paired-like homeobox 2.45203
TRAPPC8 trafficking protein particle complex 8 2.44029
SEC23A Sec23 homolog A (S. cerevisiae) 2.43932
GAMT guanidinoacetate N-methyltransferase 2.42393
PXYLP1 2-phosphoxylose phosphatase 1 2.38144
LYRM7 LYR motif containing 7 2.37175
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.37075
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.36552
KLF7 Kruppel-like factor 7 (ubiquitous) 2.36552
RHOJ ras homolog family member J 2.32705
BICRA BRD4 interacting chromatin remodeling complex associated protein 2.32705
ZNF470 zinc finger protein 470 2.31484
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 2.31484
TIMM23B translocase of inner mitochondrial membrane 23 homolog B (yeast) 2.30378
PRLR prolactin receptor 2.28923
SLFN13 schlafen family member 13 2.28688
TRIML2 tripartite motif family-like 2 2.27736
ROR1 receptor tyrosine kinase-like orphan receptor 1 2.27198
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.25453
PDPN podoplanin 2.25296
FASTKD3 FAST kinase domains 3 2.25296
GRK4 G protein-coupled receptor kinase 4 2.25296
TACC3 transforming, acidic coiled-coil containing protein 3 2.24876
SMYD2 SET and MYND domain containing 2 2.24192
DOCK3 dedicator of cytokinesis 3 2.22843
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 2.22843
TEX29 testis expressed 29 2.22658
FAM13C family with sequence similarity 13, member C 2.22658
STPG2 sperm-tail PG-rich repeat containing 2 2.20378
CSK c-src tyrosine kinase 2.18723
NEU1 sialidase 1 (lysosomal sialidase) 2.17343
ANO1 anoctamin 1, calcium activated chloride channel 2.17343
MYRFL myelin regulatory factor-like 2.15688
HDAC3 histone deacetylase 3 2.15065
SUMF2 sulfatase modifying factor 2 2.13967
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 2.12238
MLIP muscular LMNA-interacting protein 2.12025
ATF2 activating transcription factor 2 2.11671
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 2.10123
NFU1 NFU1 iron-sulfur cluster scaffold 2.09991
GARNL3 GTPase activating Rap/RanGAP domain-like 3 2.09247
BOP1 block of proliferation 1 2.08826
U2SURP U2 snRNP-associated SURP domain containing 2.07433
ZNF665 zinc finger protein 665 2.07433
QTGAL queuosine-tRNA galactosyltransferase 2.06953
ZDHHC3 zinc finger, DHHC-type containing 3 2.06754
BRAP BRCA1 associated protein 2.06712
ZNF792 zinc finger protein 792 2.05413
TMTC1 transmembrane and tetratricopeptide repeat containing 1 2.05008
PRPF4 pre-mRNA processing factor 4 2.04777
UNC13A unc-13 homolog A (C. elegans) 2.04777
KNL1 kinetochore scaffold 1 2.04129
RNF182 ring finger protein 182 2.03809
PAQR3 progestin and adipoQ receptor family member III 2.03463
FGF13 fibroblast growth factor 13 2.02939
GLIPR2 GLI pathogenesis-related 2 2.01243
TMEM232 transmembrane protein 232 2.01164
MTRF1 mitochondrial translational release factor 1 2.01068

decreased expression

Symbol Name Standardized Value
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -2.49433
MASP2 mannan-binding lectin serine peptidase 2 -2.49433
MMP19 matrix metallopeptidase 19 -2.49433
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.49433
BRMS1 breast cancer metastasis suppressor 1 -2.49433
ZNF563 zinc finger protein 563 -2.49433
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.49433
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -2.49433
TM6SF1 transmembrane 6 superfamily member 1 -2.49433
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 -2.49433
HSPB2 heat shock 27kDa protein 2 -2.49433
RASGRP4 RAS guanyl releasing protein 4 -2.49433
NUTM1 NUT midline carcinoma, family member 1 -2.49433
MAN2C1 mannosidase, alpha, class 2C, member 1 -2.49433
MAP1A microtubule-associated protein 1A -2.49433
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.49433
MYL11 myosin light chain 11 -2.49433
THAP12 THAP domain containing 12 -2.49433
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like -2.49433
SINHCAF SIN3-HDAC complex associated factor -2.49433
KLK7 kallikrein-related peptidase 7 -2.49433
ZNF70 zinc finger protein 70 -2.49433
GAL3ST4 galactose-3-O-sulfotransferase 4 -2.47387
TXN2 thioredoxin 2 -2.46267
VPREB3 pre-B lymphocyte 3 -2.45203
FABP7 fatty acid binding protein 7, brain -2.45203
RGPD4 RANBP2-like and GRIP domain containing 4 -2.45203
MOGAT3 monoacylglycerol O-acyltransferase 3 -2.45203
TMEM121 transmembrane protein 121 -2.45203
ASB12 ankyrin repeat and SOCS box containing 12 -2.45203
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) -2.45203
FETUB fetuin B -2.45203
MAGIX MAGI family member, X-linked -2.45203
C9 complement component 9 -2.45203
COG2 component of oligomeric golgi complex 2 -2.45203
CFAP73 cilia and flagella associated protein 73 -2.45203
FAM3D family with sequence similarity 3, member D -2.45203
LRRD1 leucine-rich repeats and death domain containing 1 -2.45203
CX3CL1 chemokine (C-X3-C motif) ligand 1 -2.45203
HCRTR1 hypocretin (orexin) receptor 1 -2.45203
C8ORF48 chromosome 8 open reading frame 48 -2.45203
IHO1 interactor of HORMAD1 1 -2.45203
AMDHD1 amidohydrolase domain containing 1 -2.45203
CALHM2 calcium homeostasis modulator 2 -2.45203
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -2.45203
PCDHGB1 protocadherin gamma subfamily B, 1 -2.45203
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -2.45203
LMOD3 leiomodin 3 (fetal) -2.45203
ADAM8 ADAM metallopeptidase domain 8 -2.45203
THBD thrombomodulin -2.45203
SLITRK1 SLIT and NTRK-like family, member 1 -2.45203
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 -2.45203
ZBED6 zinc finger, BED-type containing 6 -2.45203
MRPL20 mitochondrial ribosomal protein L20 -2.42871
NCAPH non-SMC condensin I complex, subunit H -2.41466
KIF25 kinesin family member 25 -2.39718
TIGD3 tigger transposable element derived 3 -2.37175
TSGA10IP testis specific, 10 interacting protein -2.37175
ADAM11 ADAM metallopeptidase domain 11 -2.37175
ITPRID1 ITPR interacting domain containing 1 -2.37175
LRWD1 leucine-rich repeats and WD repeat domain containing 1 -2.36993
MRPL17 mitochondrial ribosomal protein L17 -2.34631
PVALB parvalbumin -2.34324
PITPNB phosphatidylinositol transfer protein, beta -2.32705
CDC40 cell division cycle 40 -2.28923
GRM6 glutamate receptor, metabotropic 6 -2.25296
BARX1 BARX homeobox 1 -2.25296
ZNF597 zinc finger protein 597 -2.25296
STARD5 StAR-related lipid transfer (START) domain containing 5 -2.25296
TENT5C terminal nucleotidyltransferase 5C -2.25296
DNAH12 dynein, axonemal, heavy chain 12 -2.25296
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -2.22843
RAB29 RAB29, member RAS oncogene family -2.22843
MINPP1 multiple inositol-polyphosphate phosphatase 1 -2.21169
ERCC8 excision repair cross-complementation group 8 -2.18552
CDH12 cadherin 12, type 2 (N-cadherin 2) -2.15857
CFAP298 cilia and flagella associated protein 298 -2.15857
CADM3 cell adhesion molecule 3 -2.1397
PELI1 pellino E3 ubiquitin protein ligase 1 -2.13967
ACOT9 acyl-CoA thioesterase 9 -2.12657
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 -2.12533
DUSP28 dual specificity phosphatase 28 -2.12533
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.11429
CCDC149 coiled-coil domain containing 149 -2.11429
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.11095
PCDHB4 protocadherin beta 4 -2.08826
AHCYL1 adenosylhomocysteinase-like 1 -2.075
BVES blood vessel epicardial substance -2.075
ZZZ3 zinc finger, ZZ-type containing 3 -2.07433
RAB40A RAB40A, member RAS oncogene family -2.07324
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 -2.06754
ZNF486 zinc finger protein 486 -2.06712
TNS3 tensin 3 -2.0623
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -2.04919
CYFIP1 cytoplasmic FMR1 interacting protein 1 -2.04777
MAVS mitochondrial antiviral signaling protein -2.04777
ASB16 ankyrin repeat and SOCS box containing 16 -2.04777
CAPN6 calpain 6 -2.04777
RAB6B RAB6B, member RAS oncogene family -2.0436
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -2.03364
MEI1 meiosis inhibitor 1 -2.03106
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -2.02299