MAP kinase cascade Gene Set

Dataset HumanCyc Pathways
Category structural or functional annotations
Type pathway
Description An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. (Gene Ontology, GO_0000165)
External Link
Similar Terms
Downloads & Tools


2 proteins participating in the MAP kinase cascade pathway from the HumanCyc Pathways dataset.

Symbol Name
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta