MAP-kinase scaffold activity Gene Set

Dataset GO Molecular Function Annotations 2023
Category structural or functional annotations
Type biological process
Description The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently. (Gene Ontology, GO_0005078)
External Link http://amigo.geneontology.org/amigo/term/GO:0005078
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Genes

11 genes performing the MAP-kinase scaffold activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
DUSP19 dual specificity phosphatase 19
IQGAP1 IQ motif containing GTPase activating protein 1
KSR1 kinase suppressor of ras 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
SH3RF1 SH3 domain containing ring finger 1
SPAG9 sperm associated antigen 9