MAP1LC3A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description microtubule-associated protein 1 light chain 3 alpha|MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012] (NCBI Entrez Gene Database, 84557)
External Link https://ncbi.nlm.nih.gov/gene/84557
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Genes

499 genes differentially expressed following the MAP1LC3A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0207315
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0196198
ANXA3 annexin A3 0.0140638
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.0137177
MAGEA3 melanoma antigen family A3 0.0136326
IFI27 interferon, alpha-inducible protein 27 0.0130075
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.01282
LBH limb bud and heart development 0.0127425
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0124994
ANXA1 annexin A1 0.0124608
ABLIM1 actin binding LIM protein 1 0.0121797
KLK10 kallikrein-related peptidase 10 0.0121446
ATF3 activating transcription factor 3 0.0116438
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.011434
JAG1 jagged 1 0.0110881
CXADR coxsackie virus and adenovirus receptor 0.0110863
SCD5 stearoyl-CoA desaturase 5 0.0110346
POSTN periostin, osteoblast specific factor 0.0110243
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.0110109
COG7 component of oligomeric golgi complex 7 0.0108742
IRS2 insulin receptor substrate 2 0.0107626
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.010696
MX1 MX dynamin-like GTPase 1 0.0106203
KRT81 keratin 81, type II 0.0106068
GNAS GNAS complex locus 0.0105628
CEMIP cell migration inducing protein, hyaluronan binding 0.0103861
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.0103632
KRT17 keratin 17, type I 0.0103271
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0101583
GLOD4 glyoxalase domain containing 4 0.010063
SPRR2B small proline-rich protein 2B 0.0100243
SLPI secretory leukocyte peptidase inhibitor 0.0100196
IFI16 interferon, gamma-inducible protein 16 0.0099028
IFI44L interferon-induced protein 44-like 0.00976312
GIMAP4 GTPase, IMAP family member 4 0.00968742
OLFML2A olfactomedin-like 2A 0.00956921
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00953519
S100A7 S100 calcium binding protein A7 0.00945946
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00942671
SPRR3 small proline-rich protein 3 0.00942529
LY6D lymphocyte antigen 6 complex, locus D 0.00941348
KRT6A keratin 6A, type II 0.00940302
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00928416
MYO1B myosin IB 0.00926949
INHBB inhibin, beta B 0.00924536
TRIM29 tripartite motif containing 29 0.00921612
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00918264
RRAGA Ras-related GTP binding A 0.00915924
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00908933
MMP12 matrix metallopeptidase 12 0.00905795
NRN1 neuritin 1 0.00901531
PI3 peptidase inhibitor 3, skin-derived 0.00896827
SCEL sciellin 0.0088291
MAL mal, T-cell differentiation protein 0.00882227
TLR4 toll-like receptor 4 0.00878084
BHLHE41 basic helix-loop-helix family, member e41 0.00875921
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00870504
TP63 tumor protein p63 0.00863153
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00861494
SPRR1B small proline-rich protein 1B 0.00860336
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00858052
MPO myeloperoxidase 0.00857823
EMP1 epithelial membrane protein 1 0.00856134
ALCAM activated leukocyte cell adhesion molecule 0.00851049
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.00847996
SOX11 SRY (sex determining region Y)-box 11 0.008397
PRAME preferentially expressed antigen in melanoma 0.00836826
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00834507
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00832197
CAV2 caveolin 2 0.00832124
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00824144
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00822723
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0081774
TRIM22 tripartite motif containing 22 0.00816786
LRP4 low density lipoprotein receptor-related protein 4 0.00813932
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00813547
SIRPA signal-regulatory protein alpha 0.00810754
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00807427
BMP7 bone morphogenetic protein 7 0.00803234
ADAM19 ADAM metallopeptidase domain 19 0.00800799
MYL9 myosin, light chain 9, regulatory 0.00799534
GAB2 GRB2-associated binding protein 2 0.00791792
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00791127
HIST1H2BD histone cluster 1, H2bd 0.00790725
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0079021
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00786322
PUF60 poly-U binding splicing factor 60KDa 0.00783587
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00781713
RTCA RNA 3'-terminal phosphate cyclase 0.00781522
KRT15 keratin 15, type I 0.00780946
NEBL nebulette 0.0077899
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00775042
LPAR6 lysophosphatidic acid receptor 6 0.00771176
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00769021
RALB v-ral simian leukemia viral oncogene homolog B 0.00767478
ADAM10 ADAM metallopeptidase domain 10 0.00767122
KRT13 keratin 13, type I 0.0076564
GUSBP3 glucuronidase, beta pseudogene 3 0.00764832
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00764561
ADM adrenomedullin 0.00757918
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00757034
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00753929
PADI2 peptidyl arginine deiminase, type II 0.00747223
CLIC5 chloride intracellular channel 5 0.00743746
TACSTD2 tumor-associated calcium signal transducer 2 0.00743611
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00743559
KLF4 Kruppel-like factor 4 (gut) 0.00743267
KDM5D lysine (K)-specific demethylase 5D 0.00740623
NIBAN1 niban apoptosis regulator 1 0.00738924
MYO1C myosin IC 0.00737425
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00735953
DSG3 desmoglein 3 0.00735806
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00735799
LGALS13 lectin, galactoside-binding, soluble, 13 0.00735147
GPA33 glycoprotein A33 (transmembrane) 0.00735062
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00729334
AIM2 absent in melanoma 2 0.00728214
CXCL8 chemokine (C-X-C motif) ligand 8 0.00726795
KLK11 kallikrein-related peptidase 11 0.00725529
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00724037
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00723386
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00720315
LEF1 lymphoid enhancer-binding factor 1 0.00720227
FABP4 fatty acid binding protein 4, adipocyte 0.0072003
DCT dopachrome tautomerase 0.00718216
PLPP2 phospholipid phosphatase 2 0.00715286
SORD sorbitol dehydrogenase 0.00713585
FAM198B family with sequence similarity 198, member B 0.007127
PDE4B phosphodiesterase 4B, cAMP-specific 0.00712034
TYR tyrosinase 0.0070784
HSPH1 heat shock 105kDa/110kDa protein 1 0.00707456
TMPRSS11E transmembrane protease, serine 11E 0.00705342
NLRP2 NLR family, pyrin domain containing 2 0.00702862
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00702495
IFI6 interferon, alpha-inducible protein 6 0.00701033
KRT1 keratin 1, type II 0.00699123
CCR2 chemokine (C-C motif) receptor 2 0.00698655
CST1 cystatin SN 0.00696418
MAGEA12 melanoma antigen family A12 0.00696303
IFI44 interferon-induced protein 44 0.00694226
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00693013
FZD6 frizzled class receptor 6 0.00690713
KRT6B keratin 6B, type II 0.00689424
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00689332
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00687482
SPRR1A small proline-rich protein 1A 0.00685126
MLANA melan-A 0.00684334
FABP7 fatty acid binding protein 7, brain 0.00684314
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00684248
TAGLN transgelin 0.00683285
LIF leukemia inhibitory factor 0.00682096
GIMAP5 GTPase, IMAP family member 5 0.00681025
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.00679985
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.0067713
ATP10B ATPase, class V, type 10B 0.00676222
IFNGR1 interferon gamma receptor 1 0.00675283
FGFBP1 fibroblast growth factor binding protein 1 0.00675134
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00674633
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0067319
CLDN8 claudin 8 0.0067313
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00670807
RTP4 receptor (chemosensory) transporter protein 4 0.00669783
KLK6 kallikrein-related peptidase 6 0.0066977
ANO1 anoctamin 1, calcium activated chloride channel 0.00669409
DEFB4A defensin, beta 4A 0.0066879
FAM111A family with sequence similarity 111, member A 0.00668231
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0066669
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00666462
EGR2 early growth response 2 0.00664729
NAV2 neuron navigator 2 0.0066306
TG thyroglobulin 0.00662582
TARS1 threonyl-tRNA synthetase 1 0.00661847
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00661036
ZDHHC6 zinc finger, DHHC-type containing 6 0.0066085
ANXA2P2 annexin A2 pseudogene 2 0.00660009
NFE2L3 nuclear factor, erythroid 2-like 3 0.00658849
HOXB7 homeobox B7 0.00658115
GYPC glycophorin C (Gerbich blood group) 0.00657631
ARHGAP15 Rho GTPase activating protein 15 0.00657514
SAMD9 sterile alpha motif domain containing 9 0.00657481
KLK13 kallikrein-related peptidase 13 0.00657155
RGS1 regulator of G-protein signaling 1 0.00656208
CD48 CD48 molecule 0.00654289
PLCB4 phospholipase C, beta 4 0.00649377
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00648045
FXYD3 FXYD domain containing ion transport regulator 3 0.00647464
RHCG Rh family, C glycoprotein 0.00645201
TTC17 tetratricopeptide repeat domain 17 0.00640479
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.0063998
KRT5 keratin 5, type II 0.00633095
LPXN leupaxin 0.00632924
DAZAP2 DAZ associated protein 2 0.00632572
DUOX1 dual oxidase 1 0.00628043
TRIM16 tripartite motif containing 16 0.00627053
PMEL premelanosome protein 0.0062549
OCA2 oculocutaneous albinism II 0.00625303
KDM3A lysine (K)-specific demethylase 3A 0.00625302
RAB5B RAB5B, member RAS oncogene family 0.00620659
SRSF1 serine/arginine-rich splicing factor 1 0.00620416
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00620398
CNN3 calponin 3, acidic 0.00619057
EGR1 early growth response 1 0.00618213
ACOT7 acyl-CoA thioesterase 7 0.00616199
ELANE elastase, neutrophil expressed 0.00616156
PEA15 phosphoprotein enriched in astrocytes 15 0.00616015
GIMAP6 GTPase, IMAP family member 6 0.00615584
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.00615294
RAB38 RAB38, member RAS oncogene family 0.00613187
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00613045
MNDA myeloid cell nuclear differentiation antigen 0.0061298
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.00612434
CLDND1 claudin domain containing 1 0.00611034
REEP5 receptor accessory protein 5 0.00610012
SSX1 synovial sarcoma, X breakpoint 1 0.00609992
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00608092
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0060792
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00607683
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.00606849
FOXE1 forkhead box E1 0.00606777
TARP TCR gamma alternate reading frame protein 0.00604874
LINC00623 long intergenic non-protein coding RNA 623 0.00603702
EXOC5 exocyst complex component 5 0.00603667
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00602805
PTHLH parathyroid hormone-like hormone 0.00602513
MME membrane metallo-endopeptidase 0.00602451
UBA6 ubiquitin-like modifier activating enzyme 6 0.00601494
TUG1 taurine up-regulated 1 (non-protein coding) 0.0059943
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.00598987
CTSS cathepsin S 0.00598516
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00598204
MAGEA4 melanoma antigen family A4 0.00598135
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.00597518
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.00595044
LAMP3 lysosomal-associated membrane protein 3 0.00594513
GLE1 GLE1 RNA export mediator 0.00593881
IVL involucrin 0.00592992
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00592841
TNC tenascin C 0.00589868
CAST calpastatin 0.00589822
TMEM204 transmembrane protein 204 0.00589501
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00588635
PRNP prion protein 0.00588485
CXCL10 chemokine (C-X-C motif) ligand 10 0.00588165
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.0058693
LXN latexin 0.005862
SCARB2 scavenger receptor class B, member 2 0.0058529
MYOF myoferlin 0.00583914
ESYT1 extended synaptotagmin-like protein 1 0.00583376
NMB neuromedin B 0.00582702

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0265857
ANPEP alanyl (membrane) aminopeptidase -0.0164114
AKR1C3 aldo-keto reductase family 1, member C3 -0.0159161
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0156942
TSPAN13 tetraspanin 13 -0.0154256
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0153303
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.0133945
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.0131284
FGFR3 fibroblast growth factor receptor 3 -0.0126916
FST follistatin -0.012591
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0122492
SEPP1 selenoprotein P, plasma, 1 -0.0122035
CDCA4 cell division cycle associated 4 -0.0121988
CLU clusterin -0.0109174
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0109075
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.0108824
LYZ lysozyme -0.0108576
TXNIP thioredoxin interacting protein -0.0107908
VCAM1 vascular cell adhesion molecule 1 -0.0106967
NRGN neurogranin (protein kinase C substrate, RC3) -0.0106778
ESR1 estrogen receptor 1 -0.0106256
FTH1 ferritin, heavy polypeptide 1 -0.0105542
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0105349
GSTM3 glutathione S-transferase mu 3 (brain) -0.0104708
METTL7A methyltransferase like 7A -0.0104296
CRYM crystallin, mu -0.0104192
AMDHD2 amidohydrolase domain containing 2 -0.010151
SDC2 syndecan 2 -0.0101481
TNNT1 troponin T type 1 (skeletal, slow) -0.00993227
PROM1 prominin 1 -0.00985171
MAP7 microtubule-associated protein 7 -0.00983788
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00983446
GRB14 growth factor receptor-bound protein 14 -0.00980197
SDC4 syndecan 4 -0.00977088
CYBA cytochrome b-245, alpha polypeptide -0.00971234
PTK2 protein tyrosine kinase 2 -0.00961831
COQ8A coenzyme Q8A -0.00960886
AKAP8 A kinase (PRKA) anchor protein 8 -0.00960719
TEX10 testis expressed 10 -0.00955709
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00955589
TMSB15A thymosin beta 15a -0.00953245
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00948482
AHR aryl hydrocarbon receptor -0.00937529
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00932469
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00914906
CCL19 chemokine (C-C motif) ligand 19 -0.00912496
G0S2 G0/G1 switch 2 -0.0090003
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00898608
STXBP2 syntaxin binding protein 2 -0.00891281
ZNF423 zinc finger protein 423 -0.00885653
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00882477
RAB13 RAB13, member RAS oncogene family -0.00881053
AKAP7 A kinase (PRKA) anchor protein 7 -0.00877043
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00874173
RAB40B RAB40B, member RAS oncogene family -0.00855999
PLTP phospholipid transfer protein -0.00853632
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00852375
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00823352
LEPR leptin receptor -0.0082287
KIAA0125 KIAA0125 -0.0082048
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00820293
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00814221
ANGPT1 angiopoietin 1 -0.00814118
ADIRF adipogenesis regulatory factor -0.00810087
MMP9 matrix metallopeptidase 9 -0.00809804
CST3 cystatin C -0.00808525
QPRT quinolinate phosphoribosyltransferase -0.00795484
PENK proenkephalin -0.00794106
IGFBP1 insulin-like growth factor binding protein 1 -0.00791102
PLK1 polo-like kinase 1 -0.00789411
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00788853
BAD BCL2-associated agonist of cell death -0.00786432
PSD3 pleckstrin and Sec7 domain containing 3 -0.00785829
ZNF329 zinc finger protein 329 -0.00785051
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00782386
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -0.00782119
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00780704
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00780144
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00777469
NARF nuclear prelamin A recognition factor -0.00775098
COMP cartilage oligomeric matrix protein -0.00771712
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00769825
KLF10 Kruppel-like factor 10 -0.00764556
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00762701
WDR7 WD repeat domain 7 -0.00761158
PDGFRL platelet-derived growth factor receptor-like -0.00753102
PCOLCE procollagen C-endopeptidase enhancer -0.00751415
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00748869
MLF1 myeloid leukemia factor 1 -0.0074617
PHTF2 putative homeodomain transcription factor 2 -0.00744187
KAZN kazrin, periplakin interacting protein -0.00743657
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00743356
CRY1 cryptochrome circadian clock 1 -0.00741817
DSE dermatan sulfate epimerase -0.00739901
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -0.00739424
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00734658
COLEC12 collectin sub-family member 12 -0.00733184
NINJ2 ninjurin 2 -0.00732538
RTN2 reticulon 2 -0.00730609
INSM1 insulinoma-associated 1 -0.00730362
EVA1B eva-1 homolog B (C. elegans) -0.00728657
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00726019
LAMB1 laminin, beta 1 -0.00725465
LPAR1 lysophosphatidic acid receptor 1 -0.00722512
DAPK1 death-associated protein kinase 1 -0.00720265
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00719168
PEG3 paternally expressed 3 -0.00718268
GMDS GDP-mannose 4,6-dehydratase -0.00714662
TXNDC9 thioredoxin domain containing 9 -0.00714466
DACH1 dachshund family transcription factor 1 -0.007141
MGLL monoglyceride lipase -0.00713871
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00713293
ELN elastin -0.00711082
SCRG1 stimulator of chondrogenesis 1 -0.00708258
TFPI2 tissue factor pathway inhibitor 2 -0.00704784
INSIG1 insulin induced gene 1 -0.00703236
VNN1 vanin 1 -0.00695439
CHEK2 checkpoint kinase 2 -0.00694905
NPY neuropeptide Y -0.00694095
TGFB1 transforming growth factor, beta 1 -0.00693249
MXD4 MAX dimerization protein 4 -0.00691808
TNNI2 troponin I type 2 (skeletal, fast) -0.0069162
DLK1 delta-like 1 homolog (Drosophila) -0.00688898
ZNF468 zinc finger protein 468 -0.00687804
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00686363
SUB1 SUB1 homolog (S. cerevisiae) -0.00685601
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00683274
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -0.00680527
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00680487
NPTX2 neuronal pentraxin II -0.00680073
IL1R1 interleukin 1 receptor, type I -0.00679653
GCHFR GTP cyclohydrolase I feedback regulator -0.00677552
FBXO3 F-box protein 3 -0.00674115
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.0067354
B9D1 B9 protein domain 1 -0.00672978
SIVA1 SIVA1, apoptosis-inducing factor -0.0067174
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.00666514
MMRN1 multimerin 1 -0.00664276
FOXD1 forkhead box D1 -0.00657312
NNMT nicotinamide N-methyltransferase -0.00656672
FXYD2 FXYD domain containing ion transport regulator 2 -0.0065555
STAG2 stromal antigen 2 -0.00655185
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.00654422
KRT19 keratin 19, type I -0.00653701
MACROD1 MACRO domain containing 1 -0.00651959
METRN meteorin, glial cell differentiation regulator -0.0064966
ICAM2 intercellular adhesion molecule 2 -0.0064832
PLPP3 phospholipid phosphatase 3 -0.00646509
GPSM2 G-protein signaling modulator 2 -0.00644937
MBL2 mannose-binding lectin (protein C) 2, soluble -0.0064388
OSR2 odd-skipped related transciption factor 2 -0.00642343
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -0.00639989
MECOM MDS1 and EVI1 complex locus -0.00639903
PDE10A phosphodiesterase 10A -0.00639251
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00638583
DCK deoxycytidine kinase -0.00638477
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00634773
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00632654
GAS1 growth arrest-specific 1 -0.00632366
AMD1 adenosylmethionine decarboxylase 1 -0.00631229
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.00631066
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -0.00629723
PLD3 phospholipase D family, member 3 -0.00629578
ASRGL1 asparaginase like 1 -0.0062953
DCXR dicarbonyl/L-xylulose reductase -0.0062898
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.00627638
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00625981
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00622296
PBLD phenazine biosynthesis-like protein domain containing -0.00621847
CHRDL1 chordin-like 1 -0.00620669
PRDX4 peroxiredoxin 4 -0.00620298
SIX2 SIX homeobox 2 -0.00619767
CBX6 chromobox homolog 6 -0.00618208
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00616933
CPM carboxypeptidase M -0.00613774
LDHA lactate dehydrogenase A -0.00609299
AKR1C1 aldo-keto reductase family 1, member C1 -0.00609213
PDGFD platelet derived growth factor D -0.00607414
FUCA1 fucosidase, alpha-L- 1, tissue -0.00607027
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00606996
GFI1B growth factor independent 1B transcription repressor -0.00606688
SCGB2A1 secretoglobin, family 2A, member 1 -0.00606424
TMEM38B transmembrane protein 38B -0.00605698
PLA2G12A phospholipase A2, group XIIA -0.00605035
IL13RA2 interleukin 13 receptor, alpha 2 -0.0060105
TCL1A T-cell leukemia/lymphoma 1A -0.0060008
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0059927
BLNK B-cell linker -0.00598705
ZCCHC10 zinc finger, CCHC domain containing 10 -0.00597397
STK26 serine/threonine protein kinase 26 -0.005973
HIC2 hypermethylated in cancer 2 -0.00596901
EHBP1L1 EH domain binding protein 1-like 1 -0.00596389
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00596013
SYBU syntabulin (syntaxin-interacting) -0.00595725
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00594769
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.00594677
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00593789
H1-2 H1.2 linker histone, cluster member -0.00593191
CRIP2 cysteine-rich protein 2 -0.00593141
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00592848
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00589453
AMBP alpha-1-microglobulin/bikunin precursor -0.00589383
CA2 carbonic anhydrase II -0.00589039
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00588656
COPE coatomer protein complex, subunit epsilon -0.0058857
UGCG UDP-glucose ceramide glucosyltransferase -0.00588331
CFH complement factor H -0.00587094
ANXA4 annexin A4 -0.00586882
BANP BTG3 associated nuclear protein -0.0058428
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00584271
MDK midkine (neurite growth-promoting factor 2) -0.005832
STK3 serine/threonine kinase 3 -0.00582826
HBZ hemoglobin, zeta -0.00581734
TUBGCP3 tubulin, gamma complex associated protein 3 -0.0058124
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -0.00581017
MT1F metallothionein 1F -0.00580951
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.005778
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00577671
GCAT glycine C-acetyltransferase -0.00576803
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -0.00576059
SCAND1 SCAN domain containing 1 -0.00573637
JMJD6 jumonji domain containing 6 -0.00573226
MED7 mediator complex subunit 7 -0.00573189
STK39 serine threonine kinase 39 -0.00572314
THAP7 THAP domain containing 7 -0.00570078
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00569251
PROCR protein C receptor, endothelial -0.00567787
GPS1 G protein pathway suppressor 1 -0.00567029
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00566825
ADCY9 adenylate cyclase 9 -0.00566746
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -0.00565937
SCGN secretagogin, EF-hand calcium binding protein -0.0056492
MMP1 matrix metallopeptidase 1 -0.00564233
TGFBR3 transforming growth factor, beta receptor III -0.00563843
JAG2 jagged 2 -0.0056257
BIN1 bridging integrator 1 -0.00562426
EIF1AX eukaryotic translation initiation factor 1A, X-linked -0.00562085
EPHB4 EPH receptor B4 -0.00560538
POGLUT2 protein O-glucosyltransferase 2 -0.00560199
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -0.005593
TMEM165 transmembrane protein 165 -0.00557694
PPP4C protein phosphatase 4, catalytic subunit -0.00554709
EVL Enah/Vasp-like -0.0055421
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -0.00553244
TOX3 TOX high mobility group box family member 3 -0.00552934
APOM apolipoprotein M -0.00552625
IFI30 interferon, gamma-inducible protein 30 -0.00552567
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.00552009
GPX4 glutathione peroxidase 4 -0.00551578
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00550571