MAP2K1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mitogen-activated protein kinase kinase 1|The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5604)
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Genes

412 genes differentially expressed following the MAP2K1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
STMND1 stathmin domain containing 1 2.63242
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.63242
CCDC27 coiled-coil domain containing 27 2.63242
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 2.63242
TEKT3 tektin 3 2.63242
DDR2 discoidin domain receptor tyrosine kinase 2 2.63242
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.63242
FKBPL FK506 binding protein like 2.63242
TAL2 T-cell acute lymphocytic leukemia 2 2.63242
SPEF1 sperm flagellar 1 2.63242
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.63242
RCSD1 RCSD domain containing 1 2.63242
CPSF4L cleavage and polyadenylation specific factor 4-like 2.63242
PCDHA3 protocadherin alpha 3 2.63242
LRRC74A leucine rich repeat containing 74A 2.63242
CHAD chondroadherin 2.63242
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2.63242
BRDT bromodomain, testis-specific 2.63242
MYO7A myosin VIIA 2.63242
GAS1 growth arrest-specific 1 2.63242
NOTO notochord homeobox 2.63242
S100G S100 calcium binding protein G 2.63242
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 2.63242
TMOD1 tropomodulin 1 2.63242
GMFG glia maturation factor, gamma 2.63242
GLIPR1 GLI pathogenesis-related 1 2.63242
SPATA16 spermatogenesis associated 16 2.63242
ARHGAP40 Rho GTPase activating protein 40 2.63242
PLAC1 placenta-specific 1 2.63242
CEND1 cell cycle exit and neuronal differentiation 1 2.63242
CHCT1 CHD1 helical C-terminal domain containing 1 2.63242
IRF2-DT IRF2 divergent transcript 2.63242
TMEM217 transmembrane protein 217 2.63242
SPMIP4 sperm microtubule inner protein 4 2.63242
NTF4 neurotrophin 4 2.63242
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 2.63242
CD200R1 CD200 receptor 1 2.63242
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.63089
ELMO2 engulfment and cell motility 2 2.52927
NUTF2 nuclear transport factor 2 2.46908
XG Xg blood group 2.44362
DNAH1 dynein, axonemal, heavy chain 1 2.41099
FGD5 FYVE, RhoGEF and PH domain containing 5 2.38972
RPS4X ribosomal protein S4, X-linked 2.38972
HNF4A hepatocyte nuclear factor 4, alpha 2.38778
FAM86B2 family with sequence similarity 86, member B2 2.38778
CFHR4 complement factor H-related 4 2.38778
MKX mohawk homeobox 2.38778
KCNIP3 Kv channel interacting protein 3, calsenilin 2.38778
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.38778
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.38778
KLHL35 kelch-like family member 35 2.38778
CA4 carbonic anhydrase IV 2.38778
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.38778
SEC24D SEC24 family member D 2.38778
USH1G Usher syndrome 1G (autosomal recessive) 2.38778
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.38778
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.38778
CUL4B cullin 4B 2.38778
KYNU kynureninase 2.38778
KIAA2012 KIAA2012 2.38778
NANOS3 nanos homolog 3 (Drosophila) 2.38778
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.38778
COLEC10 collectin sub-family member 10 (C-type lectin) 2.38778
ASCC3 activating signal cointegrator 1 complex subunit 3 2.38778
FAM167B family with sequence similarity 167, member B 2.38778
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 2.38778
AZGP1 alpha-2-glycoprotein 1, zinc-binding 2.38778
FBXO4 F-box protein 4 2.38778
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.38778
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.38778
MED25 mediator complex subunit 25 2.38778
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.38778
TMEM100 transmembrane protein 100 2.38778
HBA1 hemoglobin, alpha 1 2.38778
NRN1 neuritin 1 2.38778
LOC124900192 uncharacterized LOC124900192 2.38778
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 2.38778
PLN phospholamban 2.38778
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 2.38778
ADRB1 adrenoceptor beta 1 2.38778
PAPOLB poly(A) polymerase beta (testis specific) 2.38778
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.38778
OR52K2 olfactory receptor, family 52, subfamily K, member 2 2.38778
XKR3 XK, Kell blood group complex subunit-related family, member 3 2.38778
SMTNL1 smoothelin-like 1 2.38778
F5 coagulation factor V (proaccelerin, labile factor) 2.38778
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.38778
GIPC3 GIPC PDZ domain containing family, member 3 2.38778
IFT70B intraflagellar transport 70B 2.38778
ZNF723 zinc finger protein 723 2.38778
CFAP141 cilia and flagella associated protein 141 2.38778
TAMALIN trafficking regulator and scaffold protein tamalin 2.38778
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 2.38778
DNAI7 dynein axonemal intermediate chain 7 2.38778
H2BC21 H2B clustered histone 21 2.38778
TLCD3A TLC domain containing 3A 2.38778
ACP3 acid phosphatase 3 2.38778
STYXL2 serine/threonine/tyrosine interacting like 2 2.38778
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.38778
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 2.38778
DSG1 desmoglein 1 2.38778
FAM43B family with sequence similarity 43, member B 2.38778
ZBTB16 zinc finger and BTB domain containing 16 2.38778
IRF5 interferon regulatory factor 5 2.38778
CLDN2 claudin 2 2.38778
TLE6 transducin-like enhancer of split 6 2.38778
PRB2 proline-rich protein BstNI subfamily 2 2.38778
POMC proopiomelanocortin 2.38778
RAB41 RAB41, member RAS oncogene family 2.38778
ZNF436 zinc finger protein 436 2.38778
BBS5 Bardet-Biedl syndrome 5 2.38778
C3ORF80 chromosome 3 open reading frame 80 2.38778
LTF lactotransferrin 2.38778
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.38778
GDF7 growth differentiation factor 7 2.38778
HAL histidine ammonia-lyase 2.38778
C3 complement component 3 2.38778
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.38778
CLDN22 claudin 22 2.38778
FOXI2 forkhead box I2 2.38778
TMEM179 transmembrane protein 179 2.38778
TFEB transcription factor EB 2.38778
IL36G interleukin 36, gamma 2.38778
LEMD2 LEM domain containing 2 2.38778
POTEI POTE ankyrin domain family, member I 2.38778
EBF4 early B-cell factor 4 2.38778
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.38778
CNTF ciliary neurotrophic factor 2.38778
RGS17 regulator of G-protein signaling 17 2.38778
OR56A3 olfactory receptor, family 56, subfamily A, member 3 2.38778
DNAH12 dynein, axonemal, heavy chain 12 2.38778
AP4B1 adaptor-related protein complex 4, beta 1 subunit 2.38778
LYG2 lysozyme G-like 2 2.38778
GCOM1 GRINL1A complex locus 1 2.38778
HSPA1L heat shock 70kDa protein 1-like 2.38778
LRRIQ3 leucine-rich repeats and IQ motif containing 3 2.38778
EBF3 early B-cell factor 3 2.38778
DUSP26 dual specificity phosphatase 26 (putative) 2.38778
TECRL trans-2,3-enoyl-CoA reductase-like 2.38778
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 2.38778
ECM1 extracellular matrix protein 1 2.38778
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.38778
DHRS7C dehydrogenase/reductase (SDR family) member 7C 2.38778
PRSS53 protease, serine, 53 2.38778
TSPAN32 tetraspanin 32 2.38778
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 2.38778
LRRC32 leucine rich repeat containing 32 2.38778
TTBK1 tau tubulin kinase 1 2.38778
APOF apolipoprotein F 2.38778
INHA inhibin, alpha 2.38778
TMED6 transmembrane emp24 protein transport domain containing 6 2.38778
PAGE4 P antigen family, member 4 (prostate associated) 2.38778
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.38778
CRYBA4 crystallin, beta A4 2.38778
MOS v-mos Moloney murine sarcoma viral oncogene homolog 2.38778
NKX6-2 NK6 homeobox 2 2.38778
TYR tyrosinase 2.38778
CCNA1 cyclin A1 2.38778
FBXO15 F-box protein 15 2.38778
TTC29 tetratricopeptide repeat domain 29 2.38778
GOLGA8H golgin A8 family, member H 2.38778
GOLGA8M golgin A8 family, member M 2.38778
GOLGA8R golgin A8 family, member R 2.38778
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.38778
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.38778
CLEC4G C-type lectin domain family 4, member G 2.38778
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 2.38778
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.38778
DRD2 dopamine receptor D2 2.38778
PCDHGA1 protocadherin gamma subfamily A, 1 2.38778
KISS1 KiSS-1 metastasis-suppressor 2.38778
PRF1 perforin 1 (pore forming protein) 2.38778
SPATA9 spermatogenesis associated 9 2.38778
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.38778
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 2.38778
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 2.38778
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.38778
PXT1 peroxisomal, testis specific 1 2.38778
LRRC3B leucine rich repeat containing 3B 2.38778
IL34 interleukin 34 2.38778
KRTAP13-4 keratin associated protein 13-4 2.38778
RBP4 retinol binding protein 4, plasma 2.38778
RNF39 ring finger protein 39 2.38778
DNAH8 dynein, axonemal, heavy chain 8 2.38778
AOC1 amine oxidase, copper containing 1 2.38778
PRR29 proline rich 29 2.38778
NMUR1 neuromedin U receptor 1 2.38778
KIAA1755 KIAA1755 2.38778
HRC histidine rich calcium binding protein 2.38778
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.38778
NLRP3 NLR family, pyrin domain containing 3 2.38778
ASCL2 achaete-scute family bHLH transcription factor 2 2.38778
CD101 CD101 molecule 2.38778
PITX2 paired-like homeodomain 2 2.38778
TGM5 transglutaminase 5 2.38778
TSEN34 TSEN34 tRNA splicing endonuclease subunit 2.38778
PATE1 prostate and testis expressed 1 2.38778
APOL6 apolipoprotein L, 6 2.38778
HBZ hemoglobin, zeta 2.38778
RHAG Rh-associated glycoprotein 2.38778
APOA5 apolipoprotein A-V 2.38778
SLC39A12 solute carrier family 39 (zinc transporter), member 12 2.38778
MYO16 myosin XVI 2.38778
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.38778
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.38778
CCDC166 coiled-coil domain containing 166 2.38778
ALLC allantoicase 2.38778
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.38778
SPX spexin hormone 2.38778
OR5A2 olfactory receptor, family 5, subfamily A, member 2 2.38778
NT5DC1 5'-nucleotidase domain containing 1 2.38195
GALT galactose-1-phosphate uridylyltransferase 2.36483
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.3613
PELI2 pellino E3 ubiquitin protein ligase family member 2 2.33265
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 2.32913
MYL11 myosin light chain 11 2.3245
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.3245
STRADB STE20-related kinase adaptor beta 2.3245
MIIP migration and invasion inhibitory protein 2.30719
CCDC137 coiled-coil domain containing 137 2.29828
ADHFE1 alcohol dehydrogenase, iron containing, 1 2.28748
ATP5F1C ATP synthase F1 subunit gamma 2.22911
RYR2 ryanodine receptor 2 (cardiac) 2.22291
CDCA8 cell division cycle associated 8 2.21213
SLC45A4 solute carrier family 45, member 4 2.2019
EMID1 EMI domain containing 1 2.19397
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.19106
INTS7 integrator complex subunit 7 2.19065
ARHGAP8 Rho GTPase activating protein 8 2.18897
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 2.1764
RANBP17 RAN binding protein 17 2.16362
ANGPT1 angiopoietin 1 2.16189
DOLK dolichol kinase 2.16002
PCID2 PCI domain containing 2 2.14059
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 2.13746
MAP3K20 mitogen-activated protein kinase kinase kinase 20 2.13746
NISCH nischarin 2.13612
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 2.13454
ACO1 aconitase 1, soluble 2.13454
DSCC1 DNA replication and sister chromatid cohesion 1 2.11478
MRPL3 mitochondrial ribosomal protein L3 2.11223
ASF1A anti-silencing function 1A histone chaperone 2.10988
SYT17 synaptotagmin XVII 2.10988
ZNF586 zinc finger protein 586 2.10246
HM13 histocompatibility (minor) 13 2.09525
BBS4 Bardet-Biedl syndrome 4 2.08851
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 2.08848
ADGRG5 adhesion G protein-coupled receptor G5 2.08608
ETFB electron-transfer-flavoprotein, beta polypeptide 2.06099
KIRREL3 kin of IRRE like 3 (Drosophila) 2.06065
TMC7 transmembrane channel-like 7 2.06037
SBNO2 strawberry notch homolog 2 (Drosophila) 2.04477
MCRIP1 MAPK regulated corepressor interacting protein 1 2.04131
NUP54 nucleoporin 54kDa 2.03727
PRPF31 pre-mRNA processing factor 31 2.03149
ZNF66 zinc finger protein 66 2.02229
USP20 ubiquitin specific peptidase 20 2.01278
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 2.0122

decreased expression

Symbol Name Standardized Value
MAP2K1 mitogen-activated protein kinase kinase 1 -2.75419
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -2.63242
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -2.63242
FGF1 fibroblast growth factor 1 (acidic) -2.63242
GEM GTP binding protein overexpressed in skeletal muscle -2.63242
ZNF420 zinc finger protein 420 -2.63242
SCARF2 scavenger receptor class F, member 2 -2.63242
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide -2.63242
CCDC73 coiled-coil domain containing 73 -2.63242
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 -2.63242
RPS6KL1 ribosomal protein S6 kinase-like 1 -2.63242
SH2D5 SH2 domain containing 5 -2.63242
FAT2 FAT atypical cadherin 2 -2.63242
CCDC71 coiled-coil domain containing 71 -2.63242
TRIM34 tripartite motif containing 34 -2.63242
SEPTIN1 septin 1 -2.63242
ZNF415 zinc finger protein 415 -2.63242
TGFBR3L transforming growth factor, beta receptor III-like -2.63089
RAB19 RAB19, member RAS oncogene family -2.44362
UCKL1 uridine-cytidine kinase 1-like 1 -2.38972
ZNF316 zinc finger protein 316 -2.38972
LRP3 low density lipoprotein receptor-related protein 3 -2.38972
MAOA monoamine oxidase A -2.38972
INPP1 inositol polyphosphate-1-phosphatase -2.38972
OTUD1 OTU deubiquitinase 1 -2.38972
ZNF225 zinc finger protein 225 -2.38972
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 -2.38778
IFT172 intraflagellar transport 172 -2.38778
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -2.38778
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 -2.38778
SNAP25 synaptosomal-associated protein, 25kDa -2.38778
DCHS2 dachsous cadherin-related 2 -2.38778
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) -2.38778
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -2.38778
DNAH3 dynein, axonemal, heavy chain 3 -2.38778
BRI3BP BRI3 binding protein -2.38778
C8ORF76 chromosome 8 open reading frame 76 -2.38778
HBEGF heparin-binding EGF-like growth factor -2.38778
USP51 ubiquitin specific peptidase 51 -2.38778
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 -2.38778
NRROS negative regulator of reactive oxygen species -2.38778
UPP2 uridine phosphorylase 2 -2.38778
SLC16A13 solute carrier family 16, member 13 -2.38778
TOX3 TOX high mobility group box family member 3 -2.38778
MYB v-myb avian myeloblastosis viral oncogene homolog -2.38778
VSIG1 V-set and immunoglobulin domain containing 1 -2.38778
BCO2 beta-carotene oxygenase 2 -2.38778
ZIC1 Zic family member 1 -2.38778
NEURL2 neuralized E3 ubiquitin protein ligase 2 -2.38778
LPIN3 lipin 3 -2.38778
SPMIP3 sperm microtubule inner protein 3 -2.38778
OTOG otogelin -2.38778
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -2.38778
APOLD1 apolipoprotein L domain containing 1 -2.38778
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B -2.38778
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -2.38778
ZC3H11A zinc finger CCCH-type containing 11A -2.38778
FLT3 fms-related tyrosine kinase 3 -2.38778
OR2A7 olfactory receptor, family 2, subfamily A, member 7 -2.38778
PTPRE protein tyrosine phosphatase, receptor type, E -2.38778
LRP1B low density lipoprotein receptor-related protein 1B -2.38778
SSBP3 single stranded DNA binding protein 3 -2.38778
EID3 EP300 interacting inhibitor of differentiation 3 -2.38778
H2BC13 H2B clustered histone 13 -2.38778
UNC5C unc-5 homolog C (C. elegans) -2.38778
ADRA1D adrenoceptor alpha 1D -2.38778
TMX1 thioredoxin-related transmembrane protein 1 -2.38778
SLC30A10 solute carrier family 30, member 10 -2.38778
FAM222A family with sequence similarity 222, member A -2.38778
IGFBP7 insulin-like growth factor binding protein 7 -2.38778
LRRC26 leucine rich repeat containing 26 -2.38778
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled -2.38778
SHISA4 shisa family member 4 -2.38778
FBXO48 F-box protein 48 -2.38778
TTC12 tetratricopeptide repeat domain 12 -2.38778
CDCA3 cell division cycle associated 3 -2.38778
MOB3C MOB kinase activator 3C -2.38778
TPPP2 tubulin polymerization-promoting protein family member 2 -2.38778
SASS6 spindle assembly 6 homolog (C. elegans) -2.38778
POPDC3 popeye domain containing 3 -2.38778
LKAAEAR1 LKAAEAR motif containing 1 -2.38778
CRELD1 cysteine-rich with EGF-like domains 1 -2.38778
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 -2.38778
ZNF502 zinc finger protein 502 -2.37843
IRX2 iroquois homeobox 2 -2.34237
MCOLN1 mucolipin 1 -2.32913
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -2.32913
TMEM169 transmembrane protein 169 -2.32913
COMMD10 COMM domain containing 10 -2.30719
SARAF store-operated calcium entry-associated regulatory factor -2.30719
LIMK2 LIM domain kinase 2 -2.30159
SIKE1 suppressor of IKBKE 1 -2.29828
NBPF26 neuroblastoma breakpoint family, member 26 -2.29655
ZNF263 zinc finger protein 263 -2.24508
ZNF451 zinc finger protein 451 -2.22911
M6PR mannose-6-phosphate receptor (cation dependent) -2.2164
SPIN3 spindlin family, member 3 -2.20962
RYR1 ryanodine receptor 1 (skeletal) -2.20526
CLDN1 claudin 1 -2.2019
DXO decapping exoribonuclease -2.2019
CD36 CD36 molecule (thrombospondin receptor) -2.2019
DNAH7 dynein, axonemal, heavy chain 7 -2.2019
PHF20L1 PHD finger protein 20-like 1 -2.1793
GPSM1 G-protein signaling modulator 1 -2.17073
TSC1 tuberous sclerosis 1 -2.1706
CCDC14 coiled-coil domain containing 14 -2.1706
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.16564
MYORG myogenesis regulating glycosidase (putative) -2.15625
SAMD4A sterile alpha motif domain containing 4A -2.15425
TM9SF4 transmembrane 9 superfamily protein member 4 -2.14595
TRIM58 tripartite motif containing 58 -2.13746
SLC45A1 solute carrier family 45, member 1 -2.13746
PARVG parvin, gamma -2.13746
NLRP1 NLR family, pyrin domain containing 1 -2.13746
PCP4 Purkinje cell protein 4 -2.13746
CPT1B carnitine palmitoyltransferase 1B (muscle) -2.13746
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -2.13746
GRK7 G protein-coupled receptor kinase 7 -2.13746
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.13746
PPAT phosphoribosyl pyrophosphate amidotransferase -2.11706
CIAO2A cytosolic iron-sulfur assembly component 2A -2.11689
FIBCD1 fibrinogen C domain containing 1 -2.10988
IGFBP6 insulin-like growth factor binding protein 6 -2.10988
PDZD8 PDZ domain containing 8 -2.10988
KIAA1614 KIAA1614 -2.10988
MEI4 meiosis-specific 4 homolog (S. cerevisiae) -2.10988
SYNM synemin, intermediate filament protein -2.10988
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 -2.10562
HIF3A hypoxia inducible factor 3, alpha subunit -2.10246
NOSIP nitric oxide synthase interacting protein -2.09188
CDV3 CDV3 homolog (mouse) -2.08908
UBN2 ubinuclein 2 -2.08848
SPON1 spondin 1, extracellular matrix protein -2.08706
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) -2.08706
ZBTB6 zinc finger and BTB domain containing 6 -2.0831
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -2.0807
TAPT1 transmembrane anterior posterior transformation 1 -2.07939
PLPPR5 phospholipid phosphatase related 5 -2.07311
TOP2A topoisomerase (DNA) II alpha 170kDa -2.07128
TRIM25 tripartite motif containing 25 -2.06065
STEEP1 STING1 ER exit protein 1 -2.06037
EEIG2 EEIG family member 2 -2.05744
HYLS1 hydrolethalus syndrome 1 -2.05744
GSTK1 glutathione S-transferase kappa 1 -2.04525
ZNF510 zinc finger protein 510 -2.02638
FBXO34 F-box protein 34 -2.02638
MRAP2 melanocortin 2 receptor accessory protein 2 -2.02638
ZNF629 zinc finger protein 629 -2.0154
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -2.01278
FRMD4B FERM domain containing 4B -2.01278
MARCHF1 membrane associated ring-CH-type finger 1 -2.01102
DOK5 docking protein 5 -2.00551
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.00551