MAP2K7 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description mitogen-activated protein kinase kinase 7|The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 5609)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MAP2K7
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Genes

184 co-expressed genes for MAP2K7 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAM20 ADAM metallopeptidase domain 20
ADAMTSL3 ADAMTS-like 3
AKAP3 A kinase (PRKA) anchor protein 3
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANXA10 annexin A10
AOC4P amine oxidase, copper containing 4, pseudogene
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ATF2 activating transcription factor 2
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
ATXN3 ataxin 3
BRD4 bromodomain containing 4
C6 complement component 6
CA3 carbonic anhydrase III
CADM4 cell adhesion molecule 4
CALN1 calneuron 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBLN1 cerebellin 1 precursor
CDC73 cell division cycle 73
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDH8 cadherin 8, type 2
CEP162 centrosomal protein 162kDa
CLCN3 chloride channel, voltage-sensitive 3
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPB2 carboxypeptidase B2 (plasma)
CRHR1 corticotropin releasing hormone receptor 1
CTRL chymotrypsin-like
CTSB cathepsin B
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DMD dystrophin
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DRD1 dopamine receptor D1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EPHB2 EPH receptor B2
ERCC4 excision repair cross-complementation group 4
EXOC4 exocyst complex component 4
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM153B family with sequence similarity 153, member B
FAM63B family with sequence similarity 63, member B
FGA fibrinogen alpha chain
FGF18 fibroblast growth factor 18
FLJ16124
FOSL1 FOS-like antigen 1
FSHR follicle stimulating hormone receptor
FZD5 frizzled class receptor 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCA grancalcin, EF-hand calcium binding protein
GCM1 glial cells missing homolog 1 (Drosophila)
GJB5 gap junction protein, beta 5, 31.1kDa
GLRA3 glycine receptor, alpha 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR1 G protein-coupled receptor 1
GPR15 G protein-coupled receptor 15
GPR171 G protein-coupled receptor 171
GPR19 G protein-coupled receptor 19
GRIK1 glutamate receptor, ionotropic, kainate 1
GYS2 glycogen synthase 2 (liver)
HCG8 HLA complex group 8
HCRTR2 hypocretin (orexin) receptor 2
HNF1A HNF1 homeobox A
HOXB7 homeobox B7
HOXC11 homeobox C11
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA1 interferon, alpha 1
IFNA14 interferon, alpha 14
IFNW1 interferon, omega 1
IL4 interleukin 4
IL7 interleukin 7
IPO9 importin 9
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
JADE3 jade family PHD finger 3
JRKL JRK-like
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KPNA1 karyopherin alpha 1 (importin alpha 5)
KRT2 keratin 2, type II
KRT34 keratin 34, type I
LDB3 LIM domain binding 3
LECT2 leukocyte cell-derived chemotaxin 2
LGI1 leucine-rich, glioma inactivated 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LPPR4 lipid phosphate phosphatase-related protein type 4
LRP4 low density lipoprotein receptor-related protein 4
MAGEA8 melanoma antigen family A8
MAGEA9 melanoma antigen family A9
MAP2 microtubule-associated protein 2
MAP2K7 mitogen-activated protein kinase kinase 7
MASP2 mannan-binding lectin serine peptidase 2
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MON2 MON2 homolog (S. cerevisiae)
MPZL1 myelin protein zero-like 1
MYT1 myelin transcription factor 1
NEB nebulin
NHEJ1 nonhomologous end-joining factor 1
NPAS2 neuronal PAS domain protein 2
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTNG2 netrin G2
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR7A5 olfactory receptor, family 7, subfamily A, member 5
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX6 paired box 6
PAX7 paired box 7
PCM1 pericentriolar material 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PHF10 PHD finger protein 10
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOX2B paired-like homeobox 2b
PLXNA3 plexin A3
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POU6F2 POU class 6 homeobox 2
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PSD pleckstrin and Sec7 domain containing
PSG1 pregnancy specific beta-1-glycoprotein 1
PTPRR protein tyrosine phosphatase, receptor type, R
PVR poliovirus receptor
RAD51D RAD51 paralog D
RB1CC1 RB1-inducible coiled-coil 1
RBBP7 retinoblastoma binding protein 7
REPS2 RALBP1 associated Eps domain containing 2
RGS7 regulator of G-protein signaling 7
RNF24 ring finger protein 24
ROR2 receptor tyrosine kinase-like orphan receptor 2
RORB RAR-related orphan receptor B
RREB1 ras responsive element binding protein 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
RXRG retinoid X receptor, gamma
RYR3 ryanodine receptor 3
S100A5 S100 calcium binding protein A5
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SFRP4 secreted frizzled-related protein 4
SIM2 single-minded family bHLH transcription factor 2
SIX6 SIX homeobox 6
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC17A1 solute carrier family 17 (organic anion transporter), member 1
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC46A3 solute carrier family 46, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMYD3 SET and MYND domain containing 3
SOCS6 suppressor of cytokine signaling 6
SOX11 SRY (sex determining region Y)-box 11
SPA17 sperm autoantigenic protein 17
SPAG11B sperm associated antigen 11B
SPRR2C small proline-rich protein 2C (pseudogene)
SRPK3 SRSF protein kinase 3
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAC SH3 and cysteine rich domain
STARD5 StAR-related lipid transfer (START) domain containing 5
SULT4A1 sulfotransferase family 4A, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
T T, brachyury homolog (mouse)
TACC2 transforming, acidic coiled-coil containing protein 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TENM4 teneurin transmembrane protein 4
TMEM26 transmembrane protein 26
TNK1 tyrosine kinase, non-receptor, 1
TRIO trio Rho guanine nucleotide exchange factor
TSHB thyroid stimulating hormone, beta
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding)
ULK2 unc-51 like autophagy activating kinase 2
VIP vasoactive intestinal peptide
ZBTB14 zinc finger and BTB domain containing 14
ZBTB40 zinc finger and BTB domain containing 40
ZNF132 zinc finger protein 132
ZNF157 zinc finger protein 157
ZNF202 zinc finger protein 202
ZSCAN26 zinc finger and SCAN domain containing 26