| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase|The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 4214) |
| External Link | https://ncbi.nlm.nih.gov/gene/4214 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the MAP3K1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0123035 |
| STXBP2 | syntaxin binding protein 2 | 0.0118209 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0114124 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.0108237 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.0107573 |
| TCTA | T-cell leukemia translocation altered | 0.010396 |
| PLIN2 | perilipin 2 | 0.0102719 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.0101935 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00990563 |
| METRN | meteorin, glial cell differentiation regulator | 0.00966887 |
| APOD | apolipoprotein D | 0.00963404 |
| TSPYL5 | TSPY-like 5 | 0.00886331 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00860079 |
| BAG2 | BCL2-associated athanogene 2 | 0.0085384 |
| KRT19 | keratin 19, type I | 0.00846962 |
| RHOB | ras homolog family member B | 0.00846445 |
| CLU | clusterin | 0.00837376 |
| PMP22 | peripheral myelin protein 22 | 0.00820852 |
| NINJ2 | ninjurin 2 | 0.00775065 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00761466 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00760415 |
| PTK2 | protein tyrosine kinase 2 | 0.00755691 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00753947 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00753709 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00750507 |
| MXRA7 | matrix-remodelling associated 7 | 0.00740262 |
| CCNA2 | cyclin A2 | 0.00739198 |
| COMP | cartilage oligomeric matrix protein | 0.00739085 |
| FABP1 | fatty acid binding protein 1, liver | 0.00737178 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | 0.00736154 |
| TYMS | thymidylate synthetase | 0.0072232 |
| PCP4 | Purkinje cell protein 4 | 0.0072101 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00717975 |
| BGN | biglycan | 0.00714818 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00712374 |
| MB | myoglobin | 0.00707612 |
| NID1 | nidogen 1 | 0.0070366 |
| AEBP1 | AE binding protein 1 | 0.00695648 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0069188 |
| CFP | complement factor properdin | 0.00688309 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00678124 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00677561 |
| SELENBP1 | selenium binding protein 1 | 0.00677449 |
| FASN | fatty acid synthase | 0.00671929 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00668117 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00664573 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00662518 |
| APOB | apolipoprotein B | 0.0065852 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.0065521 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00654021 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | 0.00652862 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00650719 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00650124 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00648832 |
| SNX7 | sorting nexin 7 | 0.00646376 |
| CYRIA | CYFIP related Rac1 interactor A | 0.0064597 |
| CTSH | cathepsin H | 0.00645612 |
| SIKE1 | suppressor of IKBKE 1 | 0.00642887 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00636983 |
| C11ORF71 | chromosome 11 open reading frame 71 | 0.00632415 |
| ADIRF | adipogenesis regulatory factor | 0.0063053 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 0.006289 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00628441 |
| INHBA | inhibin, beta A | 0.0062706 |
| ASPN | asporin | 0.00625063 |
| PLN | phospholamban | 0.00622573 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 0.0062168 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | 0.00621065 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00617558 |
| CCND1 | cyclin D1 | 0.00607561 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00607108 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00605665 |
| KIAA0226L | KIAA0226-like | 0.00604039 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00604016 |
| EPCAM | epithelial cell adhesion molecule | 0.00602025 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00600141 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.005959 |
| SPOP | speckle-type POZ protein | 0.00595487 |
| MIS18BP1 | MIS18 binding protein 1 | 0.00593628 |
| MARCKSL1 | MARCKS-like 1 | 0.00591061 |
| MERTK | MER proto-oncogene, tyrosine kinase | 0.00590779 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00590715 |
| PLS3 | plastin 3 | 0.00587745 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00587099 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.00586451 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00581273 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00578482 |
| OLFM4 | olfactomedin 4 | 0.00577496 |
| G0S2 | G0/G1 switch 2 | 0.00574451 |
| FRZB | frizzled-related protein | 0.00574342 |
| TSPAN4 | tetraspanin 4 | 0.00574215 |
| PKN1 | protein kinase N1 | 0.00574148 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00573988 |
| CTSK | cathepsin K | 0.0057181 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 0.0057163 |
| THAP12 | THAP domain containing 12 | 0.00571621 |
| GGCT | gamma-glutamylcyclotransferase | 0.00571156 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00568293 |
| C5AR1 | complement component 5a receptor 1 | 0.00564733 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | 0.00562243 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00559584 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00559326 |
| TMEM131L | transmembrane 131 like | 0.00557873 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00557868 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00557184 |
| RSF1 | remodeling and spacing factor 1 | 0.00555176 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | 0.00554128 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0055406 |
| FADS1 | fatty acid desaturase 1 | 0.00549702 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00547914 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.00546367 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00545658 |
| PDGFC | platelet derived growth factor C | 0.00543862 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00543802 |
| RBL2 | retinoblastoma-like 2 | 0.00539163 |
| THY1 | Thy-1 cell surface antigen | 0.00539107 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00538774 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00538379 |
| CHRDL1 | chordin-like 1 | 0.00537688 |
| XAB2 | XPA binding protein 2 | 0.00535894 |
| KLF13 | Kruppel-like factor 13 | 0.00535335 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00534593 |
| GYG1 | glycogenin 1 | 0.00533037 |
| IL17RB | interleukin 17 receptor B | 0.00531386 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.00529567 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00527848 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00525604 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.00524632 |
| THBS2 | thrombospondin 2 | 0.00523044 |
| COL10A1 | collagen, type X, alpha 1 | 0.00522699 |
| CFD | complement factor D (adipsin) | 0.00521333 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00519292 |
| ALB | albumin | 0.00519184 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00516807 |
| BMP4 | bone morphogenetic protein 4 | 0.00516336 |
| ORM1 | orosomucoid 1 | 0.005151 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0051487 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.00514571 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 0.00512304 |
| HNMT | histamine N-methyltransferase | 0.00511724 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00510809 |
| STK26 | serine/threonine protein kinase 26 | 0.00509462 |
| COCH | cochlin | 0.00509408 |
| PRKCB | protein kinase C, beta | 0.00506911 |
| CHN2 | chimerin 2 | 0.00506708 |
| METTL7A | methyltransferase like 7A | 0.00506196 |
| REG3A | regenerating islet-derived 3 alpha | 0.00504666 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00504444 |
| TAGLN | transgelin | 0.00503807 |
| ANGPTL2 | angiopoietin-like 2 | 0.00502655 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00502615 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00502496 |
| SYNGR3 | synaptogyrin 3 | 0.00501178 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 0.00500499 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00498689 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00497261 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0049699 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00496727 |
| GDF15 | growth differentiation factor 15 | 0.00496167 |
| CADM1 | cell adhesion molecule 1 | 0.00493727 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.0049339 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00492192 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00489987 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.0048943 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00488869 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00488699 |
| HEPH | hephaestin | 0.00488089 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00487812 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0048716 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00485206 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00484343 |
| EFHD1 | EF-hand domain family, member D1 | 0.00484248 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00483756 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00483739 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.00482631 |
| AXL | AXL receptor tyrosine kinase | 0.004812 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00480917 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00480069 |
| MAGED1 | melanoma antigen family D1 | 0.00479636 |
| MGAM | maltase-glucoamylase | 0.00478939 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00478562 |
| CLDN3 | claudin 3 | 0.00474307 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00474263 |
| SQLE | squalene epoxidase | 0.0047341 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.00472738 |
| AHSG | alpha-2-HS-glycoprotein | 0.00472529 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00472353 |
| KRT18 | keratin 18, type I | 0.00471155 |
| GNAS | GNAS complex locus | 0.00469522 |
| PRKCZ | protein kinase C, zeta | 0.00469424 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00468395 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00467507 |
| PRKCA | protein kinase C, alpha | 0.0046591 |
| OSBPL11 | oxysterol binding protein-like 11 | 0.00465177 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00461603 |
| ATXN1 | ataxin 1 | 0.0046097 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00459994 |
| RBM7 | RNA binding motif protein 7 | 0.0045989 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00459616 |
| CHKB | choline kinase beta | 0.00455354 |
| KLHL2 | kelch-like family member 2 | 0.0045419 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00453846 |
| CD302 | CD302 molecule | 0.00453454 |
| IL6 | interleukin 6 | 0.00453405 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00452721 |
| PAX5 | paired box 5 | 0.00450813 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00449957 |
| JADE3 | jade family PHD finger 3 | 0.0044989 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.00449025 |
| RAPSN | receptor-associated protein of the synapse | 0.00448646 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00448586 |
| RXRA | retinoid X receptor, alpha | 0.00447239 |
| DIDO1 | death inducer-obliterator 1 | 0.00446613 |
| AGR2 | anterior gradient 2 | 0.00445071 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.00444974 |
| CST3 | cystatin C | 0.00444949 |
| DCLK1 | doublecortin-like kinase 1 | 0.00444908 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | 0.00444563 |
| TARDBP | TAR DNA binding protein | 0.00444516 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.0044349 |
| AHR | aryl hydrocarbon receptor | 0.00443099 |
| GPI | glucose-6-phosphate isomerase | 0.00442798 |
| SIRT3 | sirtuin 3 | 0.00442657 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00442587 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.00442509 |
| SVIL | supervillin | 0.00442239 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00442 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00439698 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00438978 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | 0.00438823 |
| BSG | basigin (Ok blood group) | 0.00438665 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00437994 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | 0.00437428 |
| ANGEL2 | angel homolog 2 (Drosophila) | 0.00437306 |
| LRRC15 | leucine rich repeat containing 15 | 0.00436767 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00436612 |
| TLN1 | talin 1 | 0.00436274 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.00435984 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | 0.00435536 |
| KLF11 | Kruppel-like factor 11 | 0.00434686 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.00434558 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.00433375 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00433022 |
| NFIB | nuclear factor I/B | 0.00432975 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.00432878 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00431271 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.00430984 |
| CD37 | CD37 molecule | 0.00430345 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COG7 | component of oligomeric golgi complex 7 | -0.0132219 |
| CA2 | carbonic anhydrase II | -0.0129786 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0122028 |
| CDCA4 | cell division cycle associated 4 | -0.0117547 |
| KLK10 | kallikrein-related peptidase 10 | -0.0103771 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0101134 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00996465 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00992998 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00945607 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00944163 |
| HOPX | HOP homeobox | -0.00916307 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.0088526 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00858427 |
| VNN1 | vanin 1 | -0.00854251 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00845633 |
| FBN2 | fibrillin 2 | -0.00828383 |
| GLOD4 | glyoxalase domain containing 4 | -0.00812526 |
| CA12 | carbonic anhydrase XII | -0.00796428 |
| DEFB4A | defensin, beta 4A | -0.00792756 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00788127 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00781412 |
| COG5 | component of oligomeric golgi complex 5 | -0.00780087 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00761548 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00760142 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0075676 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00751964 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00750537 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00749277 |
| KLK11 | kallikrein-related peptidase 11 | -0.00745667 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00743907 |
| KYNU | kynureninase | -0.00742733 |
| FCGBP | Fc fragment of IgG binding protein | -0.00742596 |
| ATF3 | activating transcription factor 3 | -0.00737118 |
| TRIM29 | tripartite motif containing 29 | -0.00730593 |
| RND3 | Rho family GTPase 3 | -0.00726061 |
| CLTB | clathrin, light chain B | -0.00725631 |
| CRNN | cornulin | -0.00721223 |
| ABLIM1 | actin binding LIM protein 1 | -0.00720912 |
| TRIM16 | tripartite motif containing 16 | -0.00716005 |
| NPR3 | natriuretic peptide receptor 3 | -0.00713825 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0071242 |
| HOXB2 | homeobox B2 | -0.00710357 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00705059 |
| MREG | melanoregulin | -0.00698976 |
| KLK13 | kallikrein-related peptidase 13 | -0.00697199 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.0069153 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00690384 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00689897 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00681836 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.0067782 |
| RPL10 | ribosomal protein L10 | -0.00664282 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0066374 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00662776 |
| SPRR3 | small proline-rich protein 3 | -0.00661869 |
| KRT6A | keratin 6A, type II | -0.00660497 |
| RGCC | regulator of cell cycle | -0.0065668 |
| WDR7 | WD repeat domain 7 | -0.00652572 |
| IVL | involucrin | -0.0064677 |
| CALML3 | calmodulin-like 3 | -0.00632139 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00632116 |
| TGM1 | transglutaminase 1 | -0.00631934 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00627791 |
| MAP7 | microtubule-associated protein 7 | -0.00625824 |
| TFF1 | trefoil factor 1 | -0.00624278 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.00622848 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.00619383 |
| SPRR1A | small proline-rich protein 1A | -0.00618006 |
| DSG3 | desmoglein 3 | -0.00613385 |
| ADM | adrenomedullin | -0.00612201 |
| TREM2 | triggering receptor expressed on myeloid cells 2 | -0.00609578 |
| CHGB | chromogranin B | -0.00606558 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00605624 |
| PSCA | prostate stem cell antigen | -0.00593688 |
| SPP1 | secreted phosphoprotein 1 | -0.00592266 |
| CCDC86 | coiled-coil domain containing 86 | -0.00587643 |
| RHCG | Rh family, C glycoprotein | -0.00586546 |
| ACP3 | acid phosphatase 3 | -0.00584692 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0058466 |
| S100A7 | S100 calcium binding protein A7 | -0.00580269 |
| EHBP1 | EH domain binding protein 1 | -0.00578269 |
| TMPRSS11D | transmembrane protease, serine 11D | -0.00577681 |
| KRT1 | keratin 1, type II | -0.00574742 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00571929 |
| ZNF160 | zinc finger protein 160 | -0.00566554 |
| A2M | alpha-2-macroglobulin | -0.00565892 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00565864 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00564985 |
| MMP12 | matrix metallopeptidase 12 | -0.00564455 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.00561192 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00559715 |
| MUC4 | mucin 4, cell surface associated | -0.00558573 |
| FRMD4B | FERM domain containing 4B | -0.00556382 |
| VLDLR | very low density lipoprotein receptor | -0.00556316 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -0.00556301 |
| CTSC | cathepsin C | -0.00555943 |
| ITGA6 | integrin, alpha 6 | -0.00554104 |
| FOXG1 | forkhead box G1 | -0.00553199 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00552199 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00551572 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00551451 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00550856 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00547209 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00546863 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00546021 |
| OXTR | oxytocin receptor | -0.00544496 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | -0.0054359 |
| KRT16 | keratin 16, type I | -0.00539103 |
| KRT17 | keratin 17, type I | -0.00536874 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 | -0.00535779 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.00531403 |
| RGS20 | regulator of G-protein signaling 20 | -0.00530677 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00528903 |
| RAB3B | RAB3B, member RAS oncogene family | -0.00528786 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00527872 |
| YIPF5 | Yip1 domain family, member 5 | -0.00526217 |
| UPK1B | uroplakin 1B | -0.00524883 |
| PLPP3 | phospholipid phosphatase 3 | -0.00524297 |
| TRAM1 | translocation associated membrane protein 1 | -0.00523752 |
| ANXA10 | annexin A10 | -0.00523724 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00523131 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00522801 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00521849 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00519521 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00518737 |
| KLK8 | kallikrein-related peptidase 8 | -0.00518016 |
| CD34 | CD34 molecule | -0.0051695 |
| GLA | galactosidase, alpha | -0.00513682 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00512684 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00511639 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | -0.00508661 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0050715 |
| FOXD1 | forkhead box D1 | -0.00507019 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00506895 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00506801 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00506386 |
| CTSG | cathepsin G | -0.00505734 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00504176 |
| RBM34 | RNA binding motif protein 34 | -0.00503839 |
| KRT13 | keratin 13, type I | -0.00503013 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00502276 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00501198 |
| CHEK2 | checkpoint kinase 2 | -0.00500177 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00497741 |
| STMN2 | stathmin 2 | -0.00496567 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00494149 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00493468 |
| NTS | neurotensin | -0.00491959 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00491296 |
| LCN2 | lipocalin 2 | -0.00490831 |
| SCEL | sciellin | -0.00490546 |
| KLK12 | kallikrein-related peptidase 12 | -0.00489307 |
| TMEM164 | transmembrane protein 164 | -0.00488465 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00488436 |
| CTSS | cathepsin S | -0.00487665 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00487574 |
| PLIN3 | perilipin 3 | -0.00486598 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.00486542 |
| UTRN | utrophin | -0.00485506 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.00484412 |
| MYRF | myelin regulatory factor | -0.00484261 |
| FOXF1 | forkhead box F1 | -0.00483907 |
| CD1C | CD1c molecule | -0.00483502 |
| LCMT1 | leucine carboxyl methyltransferase 1 | -0.00483393 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.0048273 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00482504 |
| CD320 | CD320 molecule | -0.00482169 |
| RIMBP2 | RIMS binding protein 2 | -0.00482097 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00480685 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00480478 |
| PERP | PERP, TP53 apoptosis effector | -0.00479082 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.00478665 |
| KLK7 | kallikrein-related peptidase 7 | -0.00477522 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00477019 |
| PTHLH | parathyroid hormone-like hormone | -0.00476183 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.00475398 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00475326 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00475136 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00474226 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -0.00473343 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00472856 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.00472535 |
| VWA5A | von Willebrand factor A domain containing 5A | -0.00472174 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00472115 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00471849 |
| MSMB | microseminoprotein, beta- | -0.00471684 |
| IL1R2 | interleukin 1 receptor, type II | -0.00468992 |
| MCL1 | myeloid cell leukemia 1 | -0.00468395 |
| CCDC68 | coiled-coil domain containing 68 | -0.00468336 |
| CCL22 | chemokine (C-C motif) ligand 22 | -0.00465271 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00463699 |
| PLEK2 | pleckstrin 2 | -0.0046354 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.004632 |
| TGM2 | transglutaminase 2 | -0.0046153 |
| CCNA1 | cyclin A1 | -0.00460563 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00460548 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00459857 |
| STOM | stomatin | -0.00457441 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.0045711 |
| OPHN1 | oligophrenin 1 | -0.00457031 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | -0.00455801 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00454596 |
| EPS8L1 | EPS8-like 1 | -0.00453654 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.00453447 |
| RUFY1 | RUN and FYVE domain containing 1 | -0.00453089 |
| BDKRB1 | bradykinin receptor B1 | -0.00450281 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00447675 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00444511 |
| IL36RN | interleukin 36 receptor antagonist | -0.00443637 |
| TGM3 | transglutaminase 3 | -0.0044335 |
| HOXB6 | homeobox B6 | -0.00443096 |
| EPS8L3 | EPS8-like 3 | -0.004427 |
| PF4 | platelet factor 4 | -0.00441781 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00441606 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0044127 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00440584 |
| MRC2 | mannose receptor, C type 2 | -0.00440486 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | -0.00440359 |
| ATF4 | activating transcription factor 4 | -0.00439786 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00439136 |
| PDLIM1 | PDZ and LIM domain 1 | -0.00436997 |
| CD1A | CD1a molecule | -0.00436904 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.00436469 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.00436197 |
| MALL | mal, T-cell differentiation protein-like | -0.00435191 |
| MYO1C | myosin IC | -0.00434825 |
| IER5 | immediate early response 5 | -0.00434332 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00433013 |
| METTL9 | methyltransferase like 9 | -0.00431733 |
| SPRR1B | small proline-rich protein 1B | -0.00430686 |
| CAV2 | caveolin 2 | -0.00430638 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0043053 |
| EFNA5 | ephrin-A5 | -0.00430275 |
| KLF6 | Kruppel-like factor 6 | -0.0042969 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.0042966 |
| KRT6B | keratin 6B, type II | -0.00429399 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | -0.00428799 |
| TSPO | translocator protein (18kDa) | -0.00426805 |
| CTBP2 | C-terminal binding protein 2 | -0.00426491 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00425954 |
| RAB5IF | RAB5 interacting factor | -0.00425888 |
| DUSP1 | dual specificity phosphatase 1 | -0.00425011 |
| ETHE1 | ethylmalonic encephalopathy 1 | -0.00424956 |
| SRGN | serglycin | -0.0042309 |
| PYCARD | PYD and CARD domain containing | -0.0042293 |
| ECM1 | extracellular matrix protein 1 | -0.00422094 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00421475 |
| TMEM45A | transmembrane protein 45A | -0.00421074 |
| TMPRSS11E | transmembrane protease, serine 11E | -0.00420953 |
| CLDN10 | claudin 10 | -0.00420807 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00420492 |
