MAP3K14 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description mitogen-activated protein kinase kinase kinase 14|This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9020)
External Link http://www.ncbi.nlm.nih.gov/gene/9020
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Genes

163 interacting proteins for hub protein MAP3K14 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ACTB actin, beta
ACTG1 actin gamma 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALPL alkaline phosphatase, liver/bone/kidney
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
BAG2 BCL2-associated athanogene 2
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BYSL bystin-like
C1QBP complement component 1, q subcomponent binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDC37 cell division cycle 37
CFLAR CASP8 and FADD-like apoptosis regulator
CHUK conserved helix-loop-helix ubiquitous kinase
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EDAR ectodysplasin A receptor
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EGFR epidermal growth factor receptor
EPRS glutamyl-prolyl-tRNA synthetase
EXOSC10 exosome component 10
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FBL fibrillarin
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GLUD1 glutamate dehydrogenase 1
GLUD1P5 glutamate dehydrogenase 1 pseudogene 5
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRB7 growth factor receptor-bound protein 7
GRWD1 glutamate-rich WD repeat containing 1
HIST1H1E histone cluster 1, H1e
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
IARS isoleucyl-tRNA synthetase
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1R1 interleukin 1 receptor, type I
ILF2 interleukin enhancer binding factor 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK3 mitogen-activated protein kinase 3
MAVS mitochondrial antiviral signaling protein
MLXIPL MLX interacting protein-like
MYBBP1A MYB binding protein (P160) 1a
NCK1 NCK adaptor protein 1
NCL nucleolin
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP12 NLR family, pyrin domain containing 12
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH3 notch 3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PABPC1 poly(A) binding protein, cytoplasmic 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PEBP1 phosphatidylethanolamine binding protein 1
PELI3 pellino E3 ubiquitin protein ligase family member 3
QARS glutaminyl-tRNA synthetase
RAP1B RAP1B, member of RAS oncogene family
RARA retinoic acid receptor, alpha
RARS arginyl-tRNA synthetase
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL10 ribosomal protein L10
RPL10A ribosomal protein L10a
RPL10L ribosomal protein L10-like
RPL11 ribosomal protein L11
RPL13 ribosomal protein L13
RPL14 ribosomal protein L14
RPL15 ribosomal protein L15
RPL17 ribosomal protein L17
RPL18 ribosomal protein L18
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL24 ribosomal protein L24
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL32 ribosomal protein L32
RPL35 ribosomal protein L35
RPL4 ribosomal protein L4
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL8 ribosomal protein L8
RPL9 ribosomal protein L9
RPLP0 ribosomal protein, large, P0
RPLP0P6 ribosomal protein, large, P0 pseudogene 6
RPLP2 ribosomal protein, large, P2
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS12 ribosomal protein S12
RPS13 ribosomal protein S13
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RPS5 ribosomal protein S5
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SFPQ splicing factor proline/glutamine-rich
SSB Sjogren syndrome antigen B (autoantigen La)
STAU1 staufen double-stranded RNA binding protein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TANK TRAF family member-associated NFKB activator
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF3IP2 TRAF3 interacting protein 2
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
WASF1 WAS protein family, member 1
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3