MAP3K14 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description mitogen-activated protein kinase kinase kinase 14|This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9020)
External Link https://ncbi.nlm.nih.gov/gene/9020
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Genes

497 genes differentially expressed following the MAP3K14 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like 0.0172996
FABP4 fatty acid binding protein 4, adipocyte 0.0146275
PODXL podocalyxin-like 0.0144124
ABLIM1 actin binding LIM protein 1 0.0137799
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0137363
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0136622
FMO2 flavin containing monooxygenase 2 (non-functional) 0.0133199
PBX3 pre-B-cell leukemia homeobox 3 0.0125374
NID1 nidogen 1 0.0125141
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.012432
HOPX HOP homeobox 0.0123692
S100A8 S100 calcium binding protein A8 0.0123166
KANK1 KN motif and ankyrin repeat domains 1 0.0122581
RFTN1 raftlin, lipid raft linker 1 0.0122229
PALMD palmdelphin 0.0121845
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.0120971
BST2 bone marrow stromal cell antigen 2 0.01198
NAV2 neuron navigator 2 0.0118672
PDZD2 PDZ domain containing 2 0.0114576
MIA melanoma inhibitory activity 0.0113324
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0112846
PPL periplakin 0.0110351
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.0108171
BHLHE41 basic helix-loop-helix family, member e41 0.0107873
S100A7 S100 calcium binding protein A7 0.0107505
PLK1 polo-like kinase 1 0.0107395
LIMCH1 LIM and calponin homology domains 1 0.0104661
GBP1 guanylate binding protein 1, interferon-inducible 0.0101684
KRT15 keratin 15, type I 0.0101491
CRABP2 cellular retinoic acid binding protein 2 0.0100476
MEIS2 Meis homeobox 2 0.0100133
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00997757
GBP2 guanylate binding protein 2, interferon-inducible 0.00970165
FASN fatty acid synthase 0.00937438
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00932992
CALR calreticulin 0.00921689
LGALS1 lectin, galactoside-binding, soluble, 1 0.00914214
S100A9 S100 calcium binding protein A9 0.00897431
DPYD dihydropyrimidine dehydrogenase 0.00893535
ADGRG6 adhesion G protein-coupled receptor G6 0.00891294
CD93 CD93 molecule 0.00890197
GAS1 growth arrest-specific 1 0.00886794
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00886503
C3 complement component 3 0.00885851
CRYBG1 crystallin beta-gamma domain containing 1 0.00885401
LGALS13 lectin, galactoside-binding, soluble, 13 0.00881551
PEG10 paternally expressed 10 0.00876396
XPO7 exportin 7 0.00876268
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00866497
DMD dystrophin 0.00864101
NFIB nuclear factor I/B 0.00861205
PLPP2 phospholipid phosphatase 2 0.00857925
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00849808
RGS5 regulator of G-protein signaling 5 0.0084748
NES nestin 0.00847409
FPGS folylpolyglutamate synthase 0.00844909
TSPO translocator protein (18kDa) 0.0084316
CDC25B cell division cycle 25B 0.00842388
GIMAP4 GTPase, IMAP family member 4 0.00841788
FABP7 fatty acid binding protein 7, brain 0.00832221
KRT14 keratin 14, type I 0.00831474
C1RL complement component 1, r subcomponent-like 0.00824538
PSCA prostate stem cell antigen 0.00822135
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.00821176
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0081995
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00811688
AHNAK AHNAK nucleoprotein 0.00808264
TRIM14 tripartite motif containing 14 0.00805919
USP6NL USP6 N-terminal like 0.00804692
TCTA T-cell leukemia translocation altered 0.00804088
APH1A APH1A gamma secretase subunit 0.00803731
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00803404
M6PR mannose-6-phosphate receptor (cation dependent) 0.00787309
SDC1 syndecan 1 0.00786148
NKG7 natural killer cell granule protein 7 0.00781093
CALML3 calmodulin-like 3 0.00779547
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00776235
PBX1 pre-B-cell leukemia homeobox 1 0.00776158
PDE4B phosphodiesterase 4B, cAMP-specific 0.00775618
KLHDC3 kelch domain containing 3 0.00775014
WWTR1 WW domain containing transcription regulator 1 0.00773581
LTA4H leukotriene A4 hydrolase 0.00773235
EMP2 epithelial membrane protein 2 0.00772028
MPZL2 myelin protein zero-like 2 0.00768574
APOL2 apolipoprotein L, 2 0.00762187
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00759832
TMEM45A transmembrane protein 45A 0.00757499
SOX10 SRY (sex determining region Y)-box 10 0.00756694
GAL galanin/GMAP prepropeptide 0.00755006
RUNX1 runt-related transcription factor 1 0.00754573
FMO1 flavin containing monooxygenase 1 0.00751016
LIG1 ligase I, DNA, ATP-dependent 0.00749996
OBSL1 obscurin-like 1 0.00749226
RET ret proto-oncogene 0.00749187
BTN3A1 butyrophilin, subfamily 3, member A1 0.00748273
EHD3 EH-domain containing 3 0.00738528
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00737653
PXDN peroxidasin 0.00737306
PRF1 perforin 1 (pore forming protein) 0.00736935
SCRIB scribbled planar cell polarity protein 0.00736595
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.00731012
ASCL1 achaete-scute family bHLH transcription factor 1 0.0072843
TM4SF1 transmembrane 4 L six family member 1 0.00726202
LPIN1 lipin 1 0.00725274
KRT23 keratin 23, type I 0.00724197
GOLGA8H golgin A8 family, member H 0.00723324
TAGLN2 transgelin 2 0.00720652
RTN2 reticulon 2 0.00719963
FSCN1 fascin actin-bundling protein 1 0.00719066
TGFBR3 transforming growth factor, beta receptor III 0.00713346
FZD10 frizzled class receptor 10 0.00712745
FBLN5 fibulin 5 0.00711618
GPATCH8 G patch domain containing 8 0.00708074
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.00705926
ADGRF5 adhesion G protein-coupled receptor F5 0.00701171
IRAK1 interleukin-1 receptor-associated kinase 1 0.00698075
KPNB1 karyopherin (importin) beta 1 0.00697721
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00696895
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.00694926
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00694083
ZFP36L2 ZFP36 ring finger protein-like 2 0.00686045
ZNF185 zinc finger protein 185 (LIM domain) 0.00686027
DOCK4 dedicator of cytokinesis 4 0.00685402
ANOS1 anosmin 1 0.00684993
APOL1 apolipoprotein L, 1 0.00684932
NOTCH2 notch 2 0.00684377
TMEM164 transmembrane protein 164 0.00682497
LRP4 low density lipoprotein receptor-related protein 4 0.00678823
RHOBTB3 Rho-related BTB domain containing 3 0.00678467
TLR4 toll-like receptor 4 0.00677463
DLK1 delta-like 1 homolog (Drosophila) 0.00675717
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00674434
NDRG2 NDRG family member 2 0.00672227
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00671876
CFH complement factor H 0.00669969
PDGFD platelet derived growth factor D 0.00663148
PLS3 plastin 3 0.00661723
CD36 CD36 molecule (thrombospondin receptor) 0.00660928
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00660888
TRIM29 tripartite motif containing 29 0.00660735
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00658562
NCKAP1L NCK-associated protein 1-like 0.00658136
A2M alpha-2-macroglobulin 0.0065665
OPHN1 oligophrenin 1 0.00653371
FXYD5 FXYD domain containing ion transport regulator 5 0.00652388
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00652372
UNG uracil-DNA glycosylase 0.00651057
MGST2 microsomal glutathione S-transferase 2 0.00650182
ZNF395 zinc finger protein 395 0.00649109
TNS3 tensin 3 0.00646842
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00646474
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00645427
EIF4B eukaryotic translation initiation factor 4B 0.00644618
ETV5 ets variant 5 0.00643552
ZNF106 zinc finger protein 106 0.00640914
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00640607
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00639105
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00638862
EHBP1 EH domain binding protein 1 0.00637393
OXTR oxytocin receptor 0.00637301
PI3 peptidase inhibitor 3, skin-derived 0.00637239
DCN decorin 0.00636581
CCP110 centriolar coiled coil protein 110kDa 0.0063651
BSPRY B-box and SPRY domain containing 0.0063367
IFI16 interferon, gamma-inducible protein 16 0.00631296
SSPN sarcospan 0.0063011
GSTA4 glutathione S-transferase alpha 4 0.00628292
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00627023
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00625886
DPYSL3 dihydropyrimidinase-like 3 0.00625305
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00625106
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00624714
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00624394
SRM spermidine synthase 0.00624369
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.00624157
PTPRM protein tyrosine phosphatase, receptor type, M 0.00623689
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.00623339
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.00621604
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00621515
SLPI secretory leukocyte peptidase inhibitor 0.00619666
TTN titin 0.00619226
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.00618574
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.00617038
ECPAS Ecm29 proteasome adaptor and scaffold 0.0061494
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00614033
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00613861
MTUS1 microtubule associated tumor suppressor 1 0.00613722
MSMB microseminoprotein, beta- 0.00613524
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.00610031
OLFML2A olfactomedin-like 2A 0.00609758
RSL1D1 ribosomal L1 domain containing 1 0.00607147
TMED9 transmembrane emp24 protein transport domain containing 9 0.00606857
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0060648
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00606466
NAP1L4 nucleosome assembly protein 1-like 4 0.0060645
APOD apolipoprotein D 0.00605483
CARD8 caspase recruitment domain family, member 8 0.00604837
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00604399
EPHB3 EPH receptor B3 0.00604022
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.00603903
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 0.00603744
FERMT1 fermitin family member 1 0.00603531
C10ORF10 chromosome 10 open reading frame 10 0.00602438
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.00600874
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.00600477
MACF1 microtubule-actin crosslinking factor 1 0.00600111
MLEC malectin 0.00598913
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.00598276
TYRP1 tyrosinase-related protein 1 0.00597033
SNX10 sorting nexin 10 0.00595929
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00595732
MYO1F myosin IF 0.00595716
TBC1D4 TBC1 domain family, member 4 0.00592955
EPHB4 EPH receptor B4 0.00592955
SRRM1 serine/arginine repetitive matrix 1 0.00592851
MEG3 maternally expressed 3 (non-protein coding) 0.00592454
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00591374
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00591328
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00591218
LAMA4 laminin, alpha 4 0.00591175
GLT8D2 glycosyltransferase 8 domain containing 2 0.0058862
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 0.00588482
CDV3 CDV3 homolog (mouse) 0.00586549
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00586397
SET SET nuclear proto-oncogene 0.00586319
ICMT isoprenylcysteine carboxyl methyltransferase 0.00585809
CAST calpastatin 0.00584192
LOC730101 uncharacterized LOC730101 0.00582178
SAA4 serum amyloid A4, constitutive 0.00582119
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.00579687
SORBS2 sorbin and SH3 domain containing 2 0.00579113
L1CAM L1 cell adhesion molecule 0.00579095
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00578669
KLK12 kallikrein-related peptidase 12 0.00577088
PMM2 phosphomannomutase 2 0.00574788
MYBPC1 myosin binding protein C, slow type 0.00574734
THEM6 thioesterase superfamily member 6 0.00571486
CCR2 chemokine (C-C motif) receptor 2 0.00571125
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00570933
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00568069
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00567639
IDO1 indoleamine 2,3-dioxygenase 1 0.00567523
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.00567406
PLEKHJ1 pleckstrin homology domain containing, family J member 1 0.00567138
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.00567046
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00567009
CANX calnexin 0.00566998
FZD2 frizzled class receptor 2 0.0056562
BTN3A3 butyrophilin, subfamily 3, member A3 0.00565216
ZC3H4 zinc finger CCCH-type containing 4 0.00564104

decreased expression

Symbol Name Standardized Value
H1-2 H1.2 linker histone, cluster member -0.0136198
IGFBP5 insulin-like growth factor binding protein 5 -0.0128501
TXNDC9 thioredoxin domain containing 9 -0.0125971
CKS2 CDC28 protein kinase regulatory subunit 2 -0.0122919
MLF1 myeloid leukemia factor 1 -0.0115195
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0110447
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.010805
KRT19 keratin 19, type I -0.010713
RETREG1 reticulophagy regulator 1 -0.0106297
CA2 carbonic anhydrase II -0.0106045
SEPP1 selenoprotein P, plasma, 1 -0.0105895
AKR1C3 aldo-keto reductase family 1, member C3 -0.0105004
HIST1H2AC histone cluster 1, H2ac -0.0104486
CRIP1 cysteine-rich protein 1 (intestinal) -0.0103791
TMEM106B transmembrane protein 106B -0.0103658
PDGFC platelet derived growth factor C -0.0102539
MGAM maltase-glucoamylase -0.0102074
AOC1 amine oxidase, copper containing 1 -0.00987021
PCNA proliferating cell nuclear antigen -0.00929761
FUCA1 fucosidase, alpha-L- 1, tissue -0.00901134
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00898882
GSTO1 glutathione S-transferase omega 1 -0.00890731
ITM2C integral membrane protein 2C -0.00890056
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00880573
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.0087655
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.008734
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00864381
RPS27L ribosomal protein S27-like -0.00863968
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00861891
SNRPG small nuclear ribonucleoprotein polypeptide G -0.00851534
PDCD10 programmed cell death 10 -0.00850638
INHBA inhibin, beta A -0.00847787
BIRC2 baculoviral IAP repeat containing 2 -0.00846892
FGFR2 fibroblast growth factor receptor 2 -0.00843921
COX7B cytochrome c oxidase subunit VIIb -0.00840356
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00837504
CHN2 chimerin 2 -0.00834327
CDCA4 cell division cycle associated 4 -0.00833137
NDUFA4 NDUFA4, mitochondrial complex associated -0.00830012
ST18 suppression of tumorigenicity 18, zinc finger -0.00827065
MMP9 matrix metallopeptidase 9 -0.00823339
ODC1 ornithine decarboxylase 1 -0.00823101
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00822954
UFD1 ubiquitin recognition factor in ER associated degradation 1 -0.00822386
RAB32 RAB32, member RAS oncogene family -0.00820756
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00820741
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00812113
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00804129
TFPI2 tissue factor pathway inhibitor 2 -0.00799739
VCAM1 vascular cell adhesion molecule 1 -0.00797928
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00788353
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00787735
CHKB choline kinase beta -0.00784692
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00782795
ZBTB38 zinc finger and BTB domain containing 38 -0.00780824
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00779703
HIST1H2BD histone cluster 1, H2bd -0.00778849
TPSAB1 tryptase alpha/beta 1 -0.00777302
SLC25A46 solute carrier family 25, member 46 -0.00777207
C21ORF91 chromosome 21 open reading frame 91 -0.00776229
CRYL1 crystallin, lambda 1 -0.00775692
GPNMB glycoprotein (transmembrane) nmb -0.00768708
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00768253
TEX30 testis expressed 30 -0.00764472
VEGFA vascular endothelial growth factor A -0.00764397
IL13RA2 interleukin 13 receptor, alpha 2 -0.00764233
PCP4 Purkinje cell protein 4 -0.00759618
EFNB2 ephrin-B2 -0.00756262
REG1A regenerating islet-derived 1 alpha -0.00756185
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -0.00751468
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -0.00748736
ATP5PD ATP synthase peripheral stalk subunit d -0.00748495
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00746641
SNAP29 synaptosomal-associated protein, 29kDa -0.00742296
BRD4 bromodomain containing 4 -0.00741863
IFT20 intraflagellar transport 20 -0.00741372
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00738945
MT1M metallothionein 1M -0.00737878
PFDN4 prefoldin subunit 4 -0.00733731
ZNF124 zinc finger protein 124 -0.00729534
HIST2H2BE histone cluster 2, H2be -0.00727823
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00727751
STAMBP STAM binding protein -0.00726287
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00726106
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -0.00724338
TMEM14B transmembrane protein 14B -0.00721001
GARS1 glycyl-tRNA synthetase 1 -0.00720785
UGCG UDP-glucose ceramide glucosyltransferase -0.00718306
CADM1 cell adhesion molecule 1 -0.00716584
YAP1 Yes-associated protein 1 -0.00715385
DEFA4 defensin, alpha 4, corticostatin -0.00710178
TGIF1 TGFB-induced factor homeobox 1 -0.00708215
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -0.00707676
NEO1 neogenin 1 -0.00707354
SNX13 sorting nexin 13 -0.00705749
HDDC2 HD domain containing 2 -0.0070467
LIPT1 lipoyltransferase 1 -0.00704563
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00703509
COX5B cytochrome c oxidase subunit Vb -0.00702953
COMMD8 COMM domain containing 8 -0.00702853
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00702835
DUSP14 dual specificity phosphatase 14 -0.00702037
KIAA0226L KIAA0226-like -0.00699762
COL6A2 collagen, type VI, alpha 2 -0.00698259
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00697008
HIST1H2AE histone cluster 1, H2ae -0.00696013
DEFB1 defensin, beta 1 -0.00692365
HIST1H2BH histone cluster 1, H2bh -0.00691595
HSPB11 heat shock protein family B (small), member 11 -0.00690309
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00689069
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.0068819
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00687652
CDC45 cell division cycle 45 -0.00686395
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -0.00685788
CTH cystathionine gamma-lyase -0.00684807
HDGFL3 HDGF like 3 -0.00684789
TSPAN13 tetraspanin 13 -0.00683976
ZNF165 zinc finger protein 165 -0.00683542
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00683198
GLRX glutaredoxin (thioltransferase) -0.00682401
ZNF91 zinc finger protein 91 -0.00681394
RWDD1 RWD domain containing 1 -0.00681238
NAXD NAD(P)HX dehydratase -0.00679886
GPATCH2 G patch domain containing 2 -0.00678009
LMBRD1 LMBR1 domain containing 1 -0.00677142
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00676561
DUSP5 dual specificity phosphatase 5 -0.00675544
RNF6 ring finger protein (C3H2C3 type) 6 -0.00675427
S100P S100 calcium binding protein P -0.00674487
OSTM1 osteopetrosis associated transmembrane protein 1 -0.00671236
ING1 inhibitor of growth family, member 1 -0.00669575
RAB33A RAB33A, member RAS oncogene family -0.00667317
ELF4 E74-like factor 4 (ets domain transcription factor) -0.00666838
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00663802
CDC20 cell division cycle 20 -0.00661876
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -0.00661552
TDP2 tyrosyl-DNA phosphodiesterase 2 -0.00660442
MIR22HG MIR22 host gene -0.00658975
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00658388
WT1 Wilms tumor 1 -0.00657609
SEC62 SEC62 homolog (S. cerevisiae) -0.00656418
CMC2 C-x(9)-C motif containing 2 -0.00656413
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00655332
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00653599
GOLIM4 golgi integral membrane protein 4 -0.00653523
RIT1 Ras-like without CAAX 1 -0.00653163
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00652303
NFE2L2 nuclear factor, erythroid 2-like 2 -0.00651706
SI sucrase-isomaltase (alpha-glucosidase) -0.0064928
LYPLA1 lysophospholipase I -0.00646863
ELL2 elongation factor, RNA polymerase II, 2 -0.00645517
F13A1 coagulation factor XIII, A1 polypeptide -0.00645507
CLGN calmegin -0.00643275
PTER phosphotriesterase related -0.00641038
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.00638963
CPB1 carboxypeptidase B1 (tissue) -0.00638949
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00638915
CGRRF1 cell growth regulator with ring finger domain 1 -0.00638816
ZBTB18 zinc finger and BTB domain containing 18 -0.00638587
TRIB3 tribbles pseudokinase 3 -0.00637191
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00636603
BUD31 BUD31 homolog (S. cerevisiae) -0.00636082
EGR1 early growth response 1 -0.00636069
ORC4 origin recognition complex, subunit 4 -0.0063582
MED28 mediator complex subunit 28 -0.00634965
JAG1 jagged 1 -0.0063492
RGS10 regulator of G-protein signaling 10 -0.00634435
WTAP Wilms tumor 1 associated protein -0.00633199
G0S2 G0/G1 switch 2 -0.00632779
PRKCB protein kinase C, beta -0.00632645
CCL20 chemokine (C-C motif) ligand 20 -0.00632429
ING2 inhibitor of growth family, member 2 -0.00630662
ITCH itchy E3 ubiquitin protein ligase -0.00629983
AGA aspartylglucosaminidase -0.00629571
MRPL57 mitochondrial ribosomal protein L57 -0.00627108
C11ORF24 chromosome 11 open reading frame 24 -0.00626843
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.00624757
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00623613
CPVL carboxypeptidase, vitellogenic-like -0.00622641
DNALI1 dynein, axonemal, light intermediate chain 1 -0.00621591
BBIP1 BBSome interacting protein 1 -0.00620069
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00619718
ZNF443 zinc finger protein 443 -0.00618264
REG3A regenerating islet-derived 3 alpha -0.00617643
BPGM 2,3-bisphosphoglycerate mutase -0.00615461
FAM162A family with sequence similarity 162, member A -0.00615135
CTSZ cathepsin Z -0.00615034
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.00614829
CPA3 carboxypeptidase A3 (mast cell) -0.00614585
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00614285
PELI2 pellino E3 ubiquitin protein ligase family member 2 -0.00613183
WSB1 WD repeat and SOCS box containing 1 -0.00612905
CST3 cystatin C -0.00611847
SAR1B secretion associated, Ras related GTPase 1B -0.00611409
DCK deoxycytidine kinase -0.00611095
ZNF430 zinc finger protein 430 -0.00610826
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00609184
SNRPB2 small nuclear ribonucleoprotein polypeptide B -0.00606403
RRAGC Ras-related GTP binding C -0.00605716
TMEM59 transmembrane protein 59 -0.00605463
STX8 syntaxin 8 -0.00605263
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.00603135
DDIT3 DNA-damage-inducible transcript 3 -0.00602794
TMEM185B transmembrane protein 185B -0.0060123
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00599126
SELENOT selenoprotein T -0.00598661
SEC61G Sec61 gamma subunit -0.0059838
CLDN3 claudin 3 -0.00597706
C1D C1D nuclear receptor corepressor -0.00597593
TP53TG1 TP53 target 1 (non-protein coding) -0.00595029
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.00594444
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00592874
THAP1 THAP domain containing, apoptosis associated protein 1 -0.00592821
SH3BGR SH3 domain binding glutamate-rich protein -0.00592595
LRP12 low density lipoprotein receptor-related protein 12 -0.00592417
CLCA1 chloride channel accessory 1 -0.00591863
PTS 6-pyruvoyltetrahydropterin synthase -0.00591099
AQP1 aquaporin 1 (Colton blood group) -0.00590975
DEF8 differentially expressed in FDCP 8 homolog (mouse) -0.00590896
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.0058923
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00588412
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -0.00587237
ZNF410 zinc finger protein 410 -0.00587217
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00586511
SLC38A1 solute carrier family 38, member 1 -0.00585801
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00583807
CSNK1A1 casein kinase 1, alpha 1 -0.00583437
KRT20 keratin 20, type I -0.00582678
PPIC peptidylprolyl isomerase C (cyclophilin C) -0.0058144
OLA1 Obg-like ATPase 1 -0.00580771
RPL26L1 ribosomal protein L26-like 1 -0.00580698
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00579174
SLC38A2 solute carrier family 38, member 2 -0.00578162
STK17A serine/threonine kinase 17a -0.00577036
PBLD phenazine biosynthesis-like protein domain containing -0.00575479
METTL5 methyltransferase like 5 -0.00575353
ANXA4 annexin A4 -0.00575351
RSL24D1 ribosomal L24 domain containing 1 -0.00574434
PENK proenkephalin -0.005739
STC2 stanniocalcin 2 -0.00573652
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -0.00573569
GEM GTP binding protein overexpressed in skeletal muscle -0.00572241
BIK BCL2-interacting killer (apoptosis-inducing) -0.00572015
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00570992
IFI6 interferon, alpha-inducible protein 6 -0.00570747
GUK1 guanylate kinase 1 -0.00569714
LARP6 La ribonucleoprotein domain family, member 6 -0.00569197