MAP3K14 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description mitogen-activated protein kinase kinase kinase 14|This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9020)
External Link http://www.ncbi.nlm.nih.gov/gene/9020
Similar Terms
Downloads & Tools

Genes

292 interacting proteins for MAP3K14 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTB actin, beta
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALPL alkaline phosphatase, liver/bone/kidney
ALYREF Aly/REF export factor
ANXA2 annexin A2
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP3B2 adaptor-related protein complex 3, beta 2 subunit
ARHGAP17 Rho GTPase activating protein 17
ARHGAP21 Rho GTPase activating protein 21
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
BAG2 BCL2-associated athanogene 2
BCLAF1 BCL2-associated transcription factor 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BOLA2 bolA family member 2
BSN bassoon presynaptic cytomatrix protein
BYSL bystin-like
C1QBP complement component 1, q subcomponent binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPN1 calpain 1, (mu/I) large subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDC37 cell division cycle 37
CDK13 cyclin-dependent kinase 13
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK7 cyclin-dependent kinase 7
CENPF centromere protein F, 350/400kDa
CFL1 cofilin 1 (non-muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CHUK conserved helix-loop-helix ubiquitous kinase
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CPNE1 copine I
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSN2 casein beta
CSNK1A1L casein kinase 1, alpha 1-like
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CUL5 cullin 5
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DGKE diacylglycerol kinase, epsilon 64kDa
DGKZ diacylglycerol kinase, zeta
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EDAR ectodysplasin A receptor
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGFR epidermal growth factor receptor
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4B eukaryotic translation initiation factor 4B
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPRS glutamyl-prolyl-tRNA synthetase
ERH enhancer of rudimentary homolog (Drosophila)
EXOSC10 exosome component 10
FADD Fas (TNFRSF6)-associated via death domain
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FBL fibrillarin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLNA filamin A, alpha
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GLUD1 glutamate dehydrogenase 1
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRB7 growth factor receptor-bound protein 7
GRWD1 glutamate-rich WD repeat containing 1
GSN gelsolin
H1FX H1 histone family, member X
H2AFX H2A histone family, member X
HDAC2 histone deacetylase 2
HIST1H1A histone cluster 1, H1a
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HIST2H2AB histone cluster 2, H2ab
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HTATSF1 HIV-1 Tat specific factor 1
IARS isoleucyl-tRNA synthetase
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1R1 interleukin 1 receptor, type I
ILF2 interleukin enhancer binding factor 2
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KPNB1 karyopherin (importin) beta 1
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LRP11 low density lipoprotein receptor-related protein 11
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MOB1A MOB kinase activator 1A
MYBBP1A MYB binding protein (P160) 1a
MYH9 myosin, heavy chain 9, non-muscle
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO1C myosin IC
MYOCD myocardin
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOLC1 nucleolar and coiled-body phosphoprotein 1
NONO non-POU domain containing, octamer-binding
NOP10 NOP10 ribonucleoprotein
NOP56 NOP56 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRF1 nuclear respiratory factor 1
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUCLEOLIN nucleolin multifunctional protein
PABPC1 poly(A) binding protein, cytoplasmic 1
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PDE4D phosphodiesterase 4D, cAMP-specific
PEBP1 phosphatidylethanolamine binding protein 1
PELI3 pellino E3 ubiquitin protein ligase family member 3
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKM pyruvate kinase, muscle
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRMT5 protein arginine methyltransferase 5
PRPF4B pre-mRNA processing factor 4B
QARS glutaminyl-tRNA synthetase
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RANGAP1 Ran GTPase activating protein 1
RAP1B RAP1B, member of RAS oncogene family
RARS arginyl-tRNA synthetase
RBM10 RNA binding motif protein 10
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPA1 replication protein A1, 70kDa
RPL10 ribosomal protein L10
RPL10A ribosomal protein L10a
RPL10L ribosomal protein L10-like
RPL11 ribosomal protein L11
RPL12 ribosomal protein L12
RPL13 ribosomal protein L13
RPL14 ribosomal protein L14
RPL18 ribosomal protein L18
RPL19 ribosomal protein L19
RPL21 ribosomal protein L21
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL32 ribosomal protein L32
RPL35 ribosomal protein L35
RPL35A ribosomal protein L35a
RPL36 ribosomal protein L36
RPL4 ribosomal protein L4
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL8 ribosomal protein L8
RPLP0 ribosomal protein, large, P0
RPLP0P6 ribosomal protein, large, P0 pseudogene 6
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS12 ribosomal protein S12
RPS13 ribosomal protein S13
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS19 ribosomal protein S19
RPS20 ribosomal protein S20
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RPS5 ribosomal protein S5
RPS6 ribosomal protein S6
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
S100A9 S100 calcium binding protein A9
SAG S-antigen; retina and pineal gland (arrestin)
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC16A SEC16 homolog A (S. cerevisiae)
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFPQ splicing factor proline/glutamine-rich
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SPIN1 spindlin 1
SPIN3 spindlin family, member 3
SPP1 secreted phosphoprotein 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRPK2 SRSF protein kinase 2
SRRM2 serine/arginine repetitive matrix 2
SSB Sjogren syndrome antigen B (autoantigen La)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAU1 staufen double-stranded RNA binding protein 1
STK38 serine/threonine kinase 38
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMOD3 tropomodulin 3 (ubiquitous)
TMPO thymopoietin
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRADD TNFRSF1A-associated via death domain
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM28 tripartite motif containing 28
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
UBB ubiquitin B
UBC ubiquitin C
USP9X ubiquitin specific peptidase 9, X-linked
VCP valosin containing protein
VIM vimentin
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WDR77 WD repeat domain 77
WEE1 WEE1 G2 checkpoint kinase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZFP91 ZFP91 zinc finger protein
ZRANB2 zinc finger, RAN-binding domain containing 2