| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | mitogen-activated protein kinase kinase kinase 2|The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10746) |
| External Link | https://ncbi.nlm.nih.gov/gene/10746 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the MAP3K2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0160763 |
| MAP7 | microtubule-associated protein 7 | 0.0146013 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0141844 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0126409 |
| C3 | complement component 3 | 0.012418 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0123324 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0122198 |
| CCN2 | cellular communication network factor 2 | 0.0121952 |
| ASPN | asporin | 0.0117481 |
| LUM | lumican | 0.01174 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.01172 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0113664 |
| MGLL | monoglyceride lipase | 0.0113574 |
| MFAP5 | microfibrillar associated protein 5 | 0.0113151 |
| CD93 | CD93 molecule | 0.0109979 |
| MSLN | mesothelin | 0.0107731 |
| COMP | cartilage oligomeric matrix protein | 0.0107191 |
| NNMT | nicotinamide N-methyltransferase | 0.0106987 |
| KLF6 | Kruppel-like factor 6 | 0.0106466 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.0104907 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0104584 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0104229 |
| PON3 | paraoxonase 3 | 0.0101265 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0100447 |
| MVP | major vault protein | 0.00998993 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00998152 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00963034 |
| IRS2 | insulin receptor substrate 2 | 0.00961408 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00953727 |
| FBLN5 | fibulin 5 | 0.00952381 |
| DCN | decorin | 0.00951792 |
| FILIP1L | filamin A interacting protein 1-like | 0.00950501 |
| AK1 | adenylate kinase 1 | 0.00948918 |
| RRAGA | Ras-related GTP binding A | 0.00945932 |
| FBLN2 | fibulin 2 | 0.00942243 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00940392 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00935934 |
| THBS4 | thrombospondin 4 | 0.00932331 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00929741 |
| MXRA5 | matrix-remodelling associated 5 | 0.00923306 |
| ACKR3 | atypical chemokine receptor 3 | 0.00914172 |
| DSP | desmoplakin | 0.00904442 |
| STXBP2 | syntaxin binding protein 2 | 0.00902555 |
| CLC | Charcot-Leyden crystal galectin | 0.00886683 |
| THBS1 | thrombospondin 1 | 0.00884857 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00877355 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.00877151 |
| CFH | complement factor H | 0.00876041 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00875064 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00872555 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00871074 |
| KLK5 | kallikrein-related peptidase 5 | 0.00867728 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00865102 |
| TMEM47 | transmembrane protein 47 | 0.00850795 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00848028 |
| CALML5 | calmodulin-like 5 | 0.00839939 |
| RGS5 | regulator of G-protein signaling 5 | 0.00837547 |
| THBS2 | thrombospondin 2 | 0.00835787 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00829289 |
| ASS1 | argininosuccinate synthase 1 | 0.00824398 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00823357 |
| CLIC5 | chloride intracellular channel 5 | 0.00821949 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00821836 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00821175 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00816966 |
| INSR | insulin receptor | 0.00814961 |
| NPEPL1 | aminopeptidase-like 1 | 0.00812905 |
| FN1 | fibronectin 1 | 0.00805651 |
| MCOLN1 | mucolipin 1 | 0.0080455 |
| REC8 | REC8 meiotic recombination protein | 0.00801854 |
| GPX4 | glutathione peroxidase 4 | 0.00796883 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.00792156 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00789024 |
| NVL | nuclear VCP-like | 0.0078497 |
| CCNA1 | cyclin A1 | 0.0078483 |
| PYCARD | PYD and CARD domain containing | 0.0077846 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00776712 |
| OPHN1 | oligophrenin 1 | 0.00773433 |
| TAGLN | transgelin | 0.00773129 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00771687 |
| EPCAM | epithelial cell adhesion molecule | 0.00770429 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00766786 |
| BMP4 | bone morphogenetic protein 4 | 0.00765074 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00763959 |
| ABLIM1 | actin binding LIM protein 1 | 0.00758099 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.00757431 |
| BAG1 | BCL2-associated athanogene | 0.00753848 |
| STX3 | syntaxin 3 | 0.00753519 |
| INHBB | inhibin, beta B | 0.00753219 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00752543 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00750572 |
| LRRC15 | leucine rich repeat containing 15 | 0.00748142 |
| WDR7 | WD repeat domain 7 | 0.00741977 |
| CLEC3B | C-type lectin domain family 3, member B | 0.00741392 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00739139 |
| TXNL1 | thioredoxin-like 1 | 0.00738175 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00732394 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00730897 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0072858 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00726777 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00723747 |
| PIP | prolactin-induced protein | 0.00722212 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00721617 |
| PLIN2 | perilipin 2 | 0.00720973 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00720564 |
| MYO6 | myosin VI | 0.00719316 |
| TMEM204 | transmembrane protein 204 | 0.00717988 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00713561 |
| AEBP1 | AE binding protein 1 | 0.00712301 |
| LAMA2 | laminin, alpha 2 | 0.0071187 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00710427 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00705419 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00704768 |
| COL3A1 | collagen, type III, alpha 1 | 0.00704378 |
| CST6 | cystatin E/M | 0.00697372 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00696333 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0069468 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00694569 |
| MISP | mitotic spindle positioning | 0.00693179 |
| ATF3 | activating transcription factor 3 | 0.00692781 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00691249 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00689387 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.00687686 |
| STK10 | serine/threonine kinase 10 | 0.00686419 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00685409 |
| RGCC | regulator of cell cycle | 0.00685285 |
| KRT23 | keratin 23, type I | 0.00684907 |
| FAM50A | family with sequence similarity 50, member A | 0.00683919 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00683208 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00682143 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00681633 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00681451 |
| NID2 | nidogen 2 (osteonidogen) | 0.00678709 |
| TGFB3 | transforming growth factor, beta 3 | 0.00674591 |
| RPS27L | ribosomal protein S27-like | 0.00673073 |
| HEBP2 | heme binding protein 2 | 0.0067205 |
| ESR1 | estrogen receptor 1 | 0.00671098 |
| ASRGL1 | asparaginase like 1 | 0.00669195 |
| CST1 | cystatin SN | 0.00667583 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00667277 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00667229 |
| KLK7 | kallikrein-related peptidase 7 | 0.00665102 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00664756 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00664403 |
| IER5 | immediate early response 5 | 0.00660173 |
| ZNF423 | zinc finger protein 423 | 0.00657137 |
| MYRF | myelin regulatory factor | 0.00656976 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00655289 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00652944 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00651904 |
| PLIN1 | perilipin 1 | 0.0064845 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00645779 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00644363 |
| GOLGA8H | golgin A8 family, member H | 0.00644173 |
| PERP | PERP, TP53 apoptosis effector | 0.00643002 |
| ANXA3 | annexin A3 | 0.00640026 |
| RCAN3 | RCAN family member 3 | 0.00637651 |
| ECM1 | extracellular matrix protein 1 | 0.00634649 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00633487 |
| KLK6 | kallikrein-related peptidase 6 | 0.00632055 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00631307 |
| GAS1 | growth arrest-specific 1 | 0.00628975 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00625985 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0062502 |
| TFDP1 | transcription factor Dp-1 | 0.00623127 |
| L1CAM | L1 cell adhesion molecule | 0.00620164 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00619833 |
| MFAP4 | microfibrillar-associated protein 4 | 0.0061981 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00618889 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00618754 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00617242 |
| CES3 | carboxylesterase 3 | 0.00616362 |
| TMEM176B | transmembrane protein 176B | 0.00615559 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00611704 |
| CUL4A | cullin 4A | 0.00610979 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.0061007 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00609286 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.006092 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00608334 |
| SERF2 | small EDRK-rich factor 2 | 0.00607673 |
| PLPP2 | phospholipid phosphatase 2 | 0.00607407 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00606753 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00606448 |
| OXTR | oxytocin receptor | 0.0060549 |
| AREG | amphiregulin | 0.00605086 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0060477 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00601085 |
| EFNA1 | ephrin-A1 | 0.00600409 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.00600317 |
| CTSG | cathepsin G | 0.00600205 |
| PALMD | palmdelphin | 0.00599596 |
| KLK10 | kallikrein-related peptidase 10 | 0.0059748 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0059563 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0059427 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | 0.00594056 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00593411 |
| TMC6 | transmembrane channel-like 6 | 0.00593379 |
| CCND1 | cyclin D1 | 0.00591712 |
| AOC3 | amine oxidase, copper containing 3 | 0.00590846 |
| CLU | clusterin | 0.00590493 |
| BAG6 | BCL2-associated athanogene 6 | 0.00588406 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.0058819 |
| KLHDC2 | kelch domain containing 2 | 0.00587962 |
| RRAD | Ras-related associated with diabetes | 0.00587455 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00587433 |
| MSX1 | msh homeobox 1 | 0.0058738 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00586075 |
| EDF1 | endothelial differentiation-related factor 1 | 0.00585428 |
| GAB2 | GRB2-associated binding protein 2 | 0.00585355 |
| MECOM | MDS1 and EVI1 complex locus | 0.00582142 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00582007 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00581138 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00579521 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00578046 |
| MYL9 | myosin, light chain 9, regulatory | 0.00577858 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00577409 |
| HOXB6 | homeobox B6 | 0.00576923 |
| PXDN | peroxidasin | 0.00576673 |
| EVA1B | eva-1 homolog B (C. elegans) | 0.0057324 |
| PDZK1 | PDZ domain containing 1 | 0.00572967 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00572384 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00571664 |
| SST | somatostatin | 0.00570369 |
| TALDO1 | transaldolase 1 | 0.00566671 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00564786 |
| MCM7 | minichromosome maintenance complex component 7 | 0.00564028 |
| FLII | flightless I homolog (Drosophila) | 0.00563669 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00563057 |
| MMP10 | matrix metallopeptidase 10 | 0.00561992 |
| ILK | integrin-linked kinase | 0.0056151 |
| GAS6 | growth arrest-specific 6 | 0.00559891 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0055989 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00557226 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.00556643 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00555797 |
| GNAS | GNAS complex locus | 0.00554896 |
| KLC1 | kinesin light chain 1 | 0.00554166 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00553336 |
| TCP1 | t-complex 1 | 0.00553116 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00552893 |
| FBXO2 | F-box protein 2 | 0.00552883 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00552306 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.00550824 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00550673 |
| GLOD4 | glyoxalase domain containing 4 | 0.00549496 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.0054837 |
| PNN | pinin, desmosome associated protein | 0.00546966 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00545633 |
| GRP | gastrin-releasing peptide | 0.00544923 |
| PHF10 | PHD finger protein 10 | 0.0054351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0201211 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0195642 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.0154546 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0141836 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.012704 |
| PCP4 | Purkinje cell protein 4 | -0.0126317 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0126031 |
| COPS7A | COP9 signalosome subunit 7A | -0.0114677 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0112596 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0111597 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0111091 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0110139 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0110011 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.010729 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.0106016 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0105211 |
| KRT15 | keratin 15, type I | -0.0104774 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0102249 |
| TSPAN7 | tetraspanin 7 | -0.0102044 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0100661 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.00987252 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.0098227 |
| CD9 | CD9 molecule | -0.00974725 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00968673 |
| CADM1 | cell adhesion molecule 1 | -0.00965512 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00954049 |
| PRKCA | protein kinase C, alpha | -0.00923601 |
| HIC2 | hypermethylated in cancer 2 | -0.00922663 |
| PTK2 | protein tyrosine kinase 2 | -0.00914586 |
| MAL | mal, T-cell differentiation protein | -0.00894719 |
| WIF1 | WNT inhibitory factor 1 | -0.00886462 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | -0.00869045 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00866833 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00858946 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00856235 |
| SMS | spermine synthase | -0.00849847 |
| CSTA | cystatin A (stefin A) | -0.00843159 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00821805 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00821423 |
| MMP9 | matrix metallopeptidase 9 | -0.00818623 |
| KYNU | kynureninase | -0.00812678 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00805012 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00800109 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.007984 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.0079802 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.00796718 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00794858 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00792681 |
| SNX10 | sorting nexin 10 | -0.00791086 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00789276 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00786161 |
| PDE8B | phosphodiesterase 8B | -0.00781364 |
| MXRA7 | matrix-remodelling associated 7 | -0.00780881 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00774105 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00763993 |
| PFN2 | profilin 2 | -0.00759911 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00751152 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00749514 |
| BLNK | B-cell linker | -0.00746616 |
| IL2RG | interleukin 2 receptor, gamma | -0.00744879 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0074329 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0074302 |
| MLF2 | myeloid leukemia factor 2 | -0.00742445 |
| NDRG1 | N-myc downstream regulated 1 | -0.00742202 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00741171 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.0073619 |
| ARG2 | arginase 2 | -0.00736172 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00736075 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00735184 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00734941 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00731738 |
| PRKD3 | protein kinase D3 | -0.00731103 |
| CA11 | carbonic anhydrase XI | -0.0073066 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0073022 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00725171 |
| SMIM7 | small integral membrane protein 7 | -0.00722686 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.00721921 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00721447 |
| NKX3-1 | NK3 homeobox 1 | -0.00720638 |
| CA12 | carbonic anhydrase XII | -0.00719481 |
| GAP43 | growth associated protein 43 | -0.00715664 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00713689 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00711739 |
| TNC | tenascin C | -0.00711406 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.0070799 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00695773 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0069369 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00692762 |
| MTMR2 | myotubularin related protein 2 | -0.00687707 |
| ANO3 | anoctamin 3 | -0.00686954 |
| TSPAN5 | tetraspanin 5 | -0.00685635 |
| ABI1 | abl-interactor 1 | -0.00683857 |
| SYT1 | synaptotagmin I | -0.0068381 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.0068059 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00677619 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00675707 |
| PEG10 | paternally expressed 10 | -0.0067344 |
| PRAME | preferentially expressed antigen in melanoma | -0.00672847 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00669759 |
| KRT6A | keratin 6A, type II | -0.00668218 |
| GLUL | glutamate-ammonia ligase | -0.00668005 |
| KRT13 | keratin 13, type I | -0.00666451 |
| DMXL2 | Dmx-like 2 | -0.00663744 |
| NDRG3 | NDRG family member 3 | -0.00663495 |
| S100A8 | S100 calcium binding protein A8 | -0.00662911 |
| ZNF468 | zinc finger protein 468 | -0.00660622 |
| VEGFA | vascular endothelial growth factor A | -0.0066035 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00659926 |
| LRRC40 | leucine rich repeat containing 40 | -0.00659889 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00659754 |
| NTAQ1 | N-terminal glutamine amidase 1 | -0.00658867 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00657574 |
| MAGEA3 | melanoma antigen family A3 | -0.00655518 |
| NMD3 | NMD3 ribosome export adaptor | -0.00655413 |
| TMEM183A | transmembrane protein 183A | -0.00654489 |
| FGF13 | fibroblast growth factor 13 | -0.00653718 |
| FAM172A | family with sequence similarity 172, member A | -0.00653369 |
| COG7 | component of oligomeric golgi complex 7 | -0.00652464 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00652224 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00650865 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | -0.00649834 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00647315 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00647176 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0064534 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00644202 |
| ZNF45 | zinc finger protein 45 | -0.00643356 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | -0.00642979 |
| DMXL1 | Dmx-like 1 | -0.00641344 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00639876 |
| PFKM | phosphofructokinase, muscle | -0.00635263 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | -0.00632932 |
| PKM | pyruvate kinase, muscle | -0.00632764 |
| GPM6A | glycoprotein M6A | -0.006327 |
| CHI3L2 | chitinase 3-like 2 | -0.00632096 |
| XPO7 | exportin 7 | -0.00631058 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00628473 |
| RCAN1 | regulator of calcineurin 1 | -0.00627666 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | -0.00626901 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00625636 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 | -0.0062563 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0062372 |
| SYNGR3 | synaptogyrin 3 | -0.00622363 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00621972 |
| PDGFC | platelet derived growth factor C | -0.00621458 |
| NCOA1 | nuclear receptor coactivator 1 | -0.00619383 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00615894 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00615773 |
| ITGAV | integrin, alpha V | -0.00615485 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.00613434 |
| SIRT3 | sirtuin 3 | -0.00613359 |
| ZNF91 | zinc finger protein 91 | -0.00612155 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00611155 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | -0.00610111 |
| NPY | neuropeptide Y | -0.00608573 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00607546 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00605984 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | -0.00605527 |
| IL27RA | interleukin 27 receptor, alpha | -0.00604702 |
| PENK | proenkephalin | -0.00603314 |
| EFNB3 | ephrin-B3 | -0.00602838 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | -0.00601995 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00601765 |
| PRF1 | perforin 1 (pore forming protein) | -0.00598126 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | -0.00598048 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0059612 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.00595551 |
| CDC7 | cell division cycle 7 | -0.00594257 |
| CTSB | cathepsin B | -0.00593378 |
| TWF1 | twinfilin actin binding protein 1 | -0.00591596 |
| SGMS1 | sphingomyelin synthase 1 | -0.00591331 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | -0.00590585 |
| METAP1 | methionyl aminopeptidase 1 | -0.00590544 |
| ZNF239 | zinc finger protein 239 | -0.00590201 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00589564 |
| COPS4 | COP9 signalosome subunit 4 | -0.00587043 |
| GLS | glutaminase | -0.00586856 |
| KIAA0226L | KIAA0226-like | -0.0058485 |
| ATP13A3 | ATPase type 13A3 | -0.00584305 |
| LOXL2 | lysyl oxidase-like 2 | -0.00582909 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00582345 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00581223 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00580961 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 | -0.00579571 |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 | -0.00579184 |
| COCH | cochlin | -0.00578052 |
| DMD | dystrophin | -0.00576679 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00576561 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00576533 |
| GSAP | gamma-secretase activating protein | -0.00576099 |
| CLIC2 | chloride intracellular channel 2 | -0.00574913 |
| POU2AF1 | POU class 2 associating factor 1 | -0.005748 |
| PFKP | phosphofructokinase, platelet | -0.00574738 |
| DSE | dermatan sulfate epimerase | -0.00574396 |
| CHN1 | chimerin 1 | -0.00573441 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | -0.0057322 |
| CALB1 | calbindin 1, 28kDa | -0.00571345 |
| FOXG1 | forkhead box G1 | -0.00570663 |
| ACP3 | acid phosphatase 3 | -0.00570565 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.00569828 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00569727 |
| PLEK2 | pleckstrin 2 | -0.00569243 |
| STK17A | serine/threonine kinase 17a | -0.00569129 |
| DCK | deoxycytidine kinase | -0.00568751 |
| PLS3 | plastin 3 | -0.0056803 |
| STK38L | serine/threonine kinase 38 like | -0.00567327 |
| XPOT | exportin, tRNA | -0.00566536 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.00565942 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0056555 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00564263 |
| NEK7 | NIMA-related kinase 7 | -0.00563245 |
| CORO2B | coronin, actin binding protein, 2B | -0.00562432 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00562249 |
| PGAP3 | post-GPI attachment to proteins 3 | -0.00562193 |
| SELENOF | selenoprotein F | -0.00561837 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00561509 |
| KRT5 | keratin 5, type II | -0.00560368 |
| FAM168A | family with sequence similarity 168, member A | -0.00559832 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | -0.00559658 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.00558327 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0055645 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00556349 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00555817 |
| PKP1 | plakophilin 1 | -0.0055488 |
| HMGB2 | high mobility group box 2 | -0.00554703 |
| GPR88 | G protein-coupled receptor 88 | -0.0055465 |
| LIMA1 | LIM domain and actin binding 1 | -0.0055448 |
| SUSD4 | sushi domain containing 4 | -0.00554314 |
| ZNF226 | zinc finger protein 226 | -0.00552669 |
| PAK1IP1 | PAK1 interacting protein 1 | -0.00552616 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | -0.00550981 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00550339 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.00549375 |
| IRF2 | interferon regulatory factor 2 | -0.00548669 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.0054865 |
| OCRL | oculocerebrorenal syndrome of Lowe | -0.00548144 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.00547316 |
| METTL21B | methyltransferase like 21B | -0.00546945 |
| TMEM106B | transmembrane protein 106B | -0.00545674 |
| IL2RB | interleukin 2 receptor, beta | -0.00545588 |
| OPA1 | optic atrophy 1 (autosomal dominant) | -0.00545421 |
| S100A9 | S100 calcium binding protein A9 | -0.00544269 |
| STK26 | serine/threonine protein kinase 26 | -0.00543909 |
| DCP2 | decapping mRNA 2 | -0.00543599 |
| CD2 | CD2 molecule | -0.0054323 |
| CD1E | CD1e molecule | -0.00543224 |
| DBF4 | DBF4 zinc finger | -0.00543061 |
| CD27 | CD27 molecule | -0.00542043 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.00541557 |
| MSMO1 | methylsterol monooxygenase 1 | -0.005366 |
| CD247 | CD247 molecule | -0.00535992 |
