| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | mitogen-activated protein kinase kinase kinase 7|The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6885) |
| External Link | https://ncbi.nlm.nih.gov/gene/6885 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the MAP3K7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.016613 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.015367 |
| MYBPC1 | myosin binding protein C, slow type | 0.0137273 |
| SIRT3 | sirtuin 3 | 0.013709 |
| GNAS | GNAS complex locus | 0.0130961 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0126106 |
| MXRA7 | matrix-remodelling associated 7 | 0.0123877 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0114786 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0112311 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.0110124 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0109738 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0106912 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0103284 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0100722 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00999174 |
| RTN2 | reticulon 2 | 0.00993076 |
| SNX7 | sorting nexin 7 | 0.00972077 |
| TNNC1 | troponin C type 1 (slow) | 0.00967296 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00960936 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00960623 |
| ANXA3 | annexin A3 | 0.00960034 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00956055 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00953347 |
| RGS5 | regulator of G-protein signaling 5 | 0.00938001 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00925606 |
| SH3BGR | SH3 domain binding glutamate-rich protein | 0.00914013 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00909535 |
| AREG | amphiregulin | 0.00907672 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00901451 |
| KLHL41 | kelch-like family member 41 | 0.00901251 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00884292 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00871514 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00862893 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00862299 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00856396 |
| POSTN | periostin, osteoblast specific factor | 0.00845712 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00841322 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00835075 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00833788 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00829568 |
| PROM1 | prominin 1 | 0.00825509 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00809861 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00797429 |
| IFI44L | interferon-induced protein 44-like | 0.00788191 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00787882 |
| GAB2 | GRB2-associated binding protein 2 | 0.00784456 |
| COL5A2 | collagen, type V, alpha 2 | 0.00779836 |
| TTN | titin | 0.00772975 |
| COG7 | component of oligomeric golgi complex 7 | 0.00771113 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00768655 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00767605 |
| PTK2 | protein tyrosine kinase 2 | 0.00764483 |
| RBM47 | RNA binding motif protein 47 | 0.00762891 |
| CLIC5 | chloride intracellular channel 5 | 0.00762152 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | 0.00760429 |
| TCTA | T-cell leukemia translocation altered | 0.00759664 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00759411 |
| CADM1 | cell adhesion molecule 1 | 0.00751761 |
| CDC14B | cell division cycle 14B | 0.00750605 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00736995 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 0.00734811 |
| STK38L | serine/threonine kinase 38 like | 0.00733744 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00726946 |
| SLN | sarcolipin | 0.00725183 |
| ASPN | asporin | 0.00723672 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00722193 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00720983 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00716288 |
| IL17RB | interleukin 17 receptor B | 0.00711879 |
| ASS1 | argininosuccinate synthase 1 | 0.00711192 |
| CKM | creatine kinase, muscle | 0.00709549 |
| COQ8A | coenzyme Q8A | 0.00709427 |
| SMPX | small muscle protein, X-linked | 0.00707886 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00706983 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 0.00706722 |
| EGR2 | early growth response 2 | 0.00703659 |
| CP | ceruloplasmin (ferroxidase) | 0.00691737 |
| OXTR | oxytocin receptor | 0.00680375 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00677738 |
| XYLT1 | xylosyltransferase I | 0.00675736 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00674478 |
| NEK7 | NIMA-related kinase 7 | 0.00670506 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00670123 |
| RCAN1 | regulator of calcineurin 1 | 0.00669738 |
| INHBA | inhibin, beta A | 0.00666879 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00662713 |
| RSF1 | remodeling and spacing factor 1 | 0.00657778 |
| UVRAG | UV radiation resistance associated | 0.00656695 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00655697 |
| PODXL | podocalyxin-like | 0.00653233 |
| OLFML2B | olfactomedin-like 2B | 0.00652877 |
| CCND1 | cyclin D1 | 0.00649731 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.00648397 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.00646519 |
| CD93 | CD93 molecule | 0.00645906 |
| TPM3 | tropomyosin 3 | 0.00644302 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00642705 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00639296 |
| SYT1 | synaptotagmin I | 0.0063862 |
| IRF8 | interferon regulatory factor 8 | 0.00638085 |
| CLIC3 | chloride intracellular channel 3 | 0.00635828 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00634923 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00634024 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.00632852 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00627659 |
| A2M | alpha-2-macroglobulin | 0.00623728 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00622692 |
| RAB32 | RAB32, member RAS oncogene family | 0.00621995 |
| FSTL1 | follistatin-like 1 | 0.00620256 |
| PTN | pleiotrophin | 0.00619463 |
| IFI44 | interferon-induced protein 44 | 0.00618855 |
| RGCC | regulator of cell cycle | 0.00617591 |
| BEX1 | brain expressed, X-linked 1 | 0.00616926 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00616429 |
| TEX10 | testis expressed 10 | 0.00613802 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00610588 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.00609803 |
| SFTPB | surfactant protein B | 0.00609055 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00607777 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00606291 |
| MB | myoglobin | 0.00605815 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00604758 |
| TGM2 | transglutaminase 2 | 0.00603533 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00602277 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0060095 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00600313 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00599128 |
| NEBL | nebulette | 0.00598882 |
| VEGFA | vascular endothelial growth factor A | 0.00593884 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00593441 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00593212 |
| POPDC3 | popeye domain containing 3 | 0.00592398 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00591002 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00590094 |
| MX1 | MX dynamin-like GTPase 1 | 0.00588834 |
| MECOM | MDS1 and EVI1 complex locus | 0.00586748 |
| DENND1B | DENN/MADD domain containing 1B | 0.00585919 |
| THBS2 | thrombospondin 2 | 0.00584414 |
| SMAD7 | SMAD family member 7 | 0.00584323 |
| MAP7 | microtubule-associated protein 7 | 0.00582608 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00582504 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.00581947 |
| METTL5 | methyltransferase like 5 | 0.00580636 |
| CA3 | carbonic anhydrase III | 0.00579387 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00576367 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00576147 |
| TJP2 | tight junction protein 2 | 0.00575857 |
| ACTN2 | actinin, alpha 2 | 0.00575824 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00574144 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00573318 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00573006 |
| CH25H | cholesterol 25-hydroxylase | 0.00572308 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00571223 |
| KRT18 | keratin 18, type I | 0.00570909 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00570626 |
| PCNA | proliferating cell nuclear antigen | 0.00570209 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00568509 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.00567858 |
| LAMC2 | laminin, gamma 2 | 0.00566809 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00564069 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00563256 |
| CCDC90B | coiled-coil domain containing 90B | 0.00562591 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0056254 |
| UBFD1 | ubiquitin family domain containing 1 | 0.00562203 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | 0.00562059 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.00561986 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00559286 |
| CA2 | carbonic anhydrase II | 0.00559042 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00558119 |
| KCTD14 | potassium channel tetramerization domain containing 14 | 0.00555966 |
| MMP10 | matrix metallopeptidase 10 | 0.00555702 |
| TNNC2 | troponin C type 2 (fast) | 0.00551534 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00549026 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00547317 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00547072 |
| TMEM176B | transmembrane protein 176B | 0.00546839 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00545627 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00544889 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00544623 |
| TCAF1 | TRPM8 channel-associated factor 1 | 0.00541885 |
| FZD5 | frizzled class receptor 5 | 0.00540418 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.00539199 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.00539109 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00537853 |
| LDB3 | LIM domain binding 3 | 0.00537069 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00535468 |
| IRF9 | interferon regulatory factor 9 | 0.00533997 |
| PRSS23 | protease, serine, 23 | 0.00532288 |
| PLS3 | plastin 3 | 0.00531793 |
| CD8A | CD8a molecule | 0.00529647 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.00529632 |
| SMYD2 | SET and MYND domain containing 2 | 0.00528092 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 | 0.00527347 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00527116 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 | 0.0052685 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00526603 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.00526088 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00525936 |
| GLO1 | glyoxalase I | 0.00525914 |
| MYOZ2 | myozenin 2 | 0.00525566 |
| MYOT | myotilin | 0.00524101 |
| IFI35 | interferon-induced protein 35 | 0.00522796 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00521498 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00521013 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0051961 |
| LTF | lactotransferrin | 0.0051936 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00518913 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00518738 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00518407 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00518112 |
| CCDC88A | coiled-coil domain containing 88A | 0.00517779 |
| FILIP1L | filamin A interacting protein 1-like | 0.00517357 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00514217 |
| S100A10 | S100 calcium binding protein A10 | 0.00513913 |
| SYNGR3 | synaptogyrin 3 | 0.00513396 |
| CFB | complement factor B | 0.00512327 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00512126 |
| CD200 | CD200 molecule | 0.00507677 |
| TMEM41B | transmembrane protein 41B | 0.0050753 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.00506379 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.00505978 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00505276 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.00504882 |
| HMBOX1 | homeobox containing 1 | 0.00504817 |
| SLC6A1 | solute carrier family 6 (neurotransmitter transporter), member 1 | 0.00504707 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00504353 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.00504226 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00503871 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00502663 |
| CARD10 | caspase recruitment domain family, member 10 | 0.00502193 |
| CCNA1 | cyclin A1 | 0.00500611 |
| MYOM2 | myomesin 2 | 0.00498065 |
| GOLIM4 | golgi integral membrane protein 4 | 0.00497154 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00497042 |
| ANXA2 | annexin A2 | 0.00496888 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00496113 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.00495861 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00494606 |
| PYGM | phosphorylase, glycogen, muscle | 0.00494177 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00493739 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00493726 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.00492996 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00492837 |
| FABP7 | fatty acid binding protein 7, brain | 0.004928 |
| TMEM176A | transmembrane protein 176A | 0.00492616 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00491481 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0049125 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00491243 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 0.00491225 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00490856 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0191428 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0163474 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.0129549 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.0128499 |
| CA12 | carbonic anhydrase XII | -0.0127934 |
| HOXC6 | homeobox C6 | -0.0117317 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0116231 |
| CDC20 | cell division cycle 20 | -0.0114505 |
| LCN2 | lipocalin 2 | -0.010616 |
| KRT15 | keratin 15, type I | -0.0101174 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0099048 |
| CSTA | cystatin A (stefin A) | -0.00969604 |
| CD9 | CD9 molecule | -0.00949609 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00940719 |
| HHEX | hematopoietically expressed homeobox | -0.00921626 |
| TMEM45A | transmembrane protein 45A | -0.00917346 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00901661 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00883118 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00871679 |
| KRT13 | keratin 13, type I | -0.00864811 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00827088 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00824031 |
| CDCA4 | cell division cycle associated 4 | -0.008211 |
| RHCG | Rh family, C glycoprotein | -0.00819214 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00803087 |
| NTS | neurotensin | -0.00801374 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00801353 |
| PLTP | phospholipid transfer protein | -0.00799331 |
| GAS1 | growth arrest-specific 1 | -0.00794884 |
| OLFM4 | olfactomedin 4 | -0.00792714 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00788451 |
| NOTCH2 | notch 2 | -0.00785123 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00777845 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00776296 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00765842 |
| S100A7 | S100 calcium binding protein A7 | -0.00757822 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00757644 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00750039 |
| CYTH1 | cytohesin 1 | -0.00745524 |
| SLC43A3 | solute carrier family 43, member 3 | -0.0074218 |
| PRKCSH | protein kinase C substrate 80K-H | -0.00740836 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0073083 |
| NVL | nuclear VCP-like | -0.00717619 |
| S100A9 | S100 calcium binding protein A9 | -0.00717461 |
| CTSC | cathepsin C | -0.00716446 |
| HMGB2 | high mobility group box 2 | -0.00709447 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00701861 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00700897 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00691504 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.006908 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00682288 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00674257 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00672529 |
| PCGF2 | polycomb group ring finger 2 | -0.00665798 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00664353 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00660021 |
| PRDX2 | peroxiredoxin 2 | -0.0065702 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00655839 |
| WASHC4 | WASH complex subunit 4 | -0.00654088 |
| CLGN | calmegin | -0.00650046 |
| IL7R | interleukin 7 receptor | -0.00644607 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00644127 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00640344 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00638119 |
| C7 | complement component 7 | -0.00635673 |
| CLU | clusterin | -0.00633435 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00630793 |
| HOXB6 | homeobox B6 | -0.00629166 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00629073 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00622679 |
| SQSTM1 | sequestosome 1 | -0.00622 |
| MAOA | monoamine oxidase A | -0.00618192 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00611158 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00608144 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | -0.00606942 |
| CHIT1 | chitinase 1 (chitotriosidase) | -0.00606748 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | -0.00606181 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.00605274 |
| TNC | tenascin C | -0.00603267 |
| KRT19 | keratin 19, type I | -0.00603214 |
| MEIS2 | Meis homeobox 2 | -0.00602368 |
| MMP7 | matrix metallopeptidase 7 | -0.00600672 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00600665 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0060064 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.00599588 |
| KYNU | kynureninase | -0.00593319 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0059272 |
| GLOD4 | glyoxalase domain containing 4 | -0.00592033 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00590558 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00590462 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00588291 |
| CPM | carboxypeptidase M | -0.00587341 |
| SPRR2B | small proline-rich protein 2B | -0.00584778 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00583248 |
| WTAP | Wilms tumor 1 associated protein | -0.00578829 |
| DCT | dopachrome tautomerase | -0.00578022 |
| MMD | monocyte to macrophage differentiation-associated | -0.00577387 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00575298 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00575209 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00572729 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00571793 |
| FCMR | Fc fragment of IgM receptor | -0.00571314 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00571308 |
| CD82 | CD82 molecule | -0.00569562 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0056891 |
| ACP3 | acid phosphatase 3 | -0.00568315 |
| EPHX3 | epoxide hydrolase 3 | -0.00565668 |
| WT1 | Wilms tumor 1 | -0.00564561 |
| DPEP1 | dipeptidase 1 (renal) | -0.00561864 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | -0.00560544 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.00558293 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00556479 |
| MAL | mal, T-cell differentiation protein | -0.00553911 |
| SPRR3 | small proline-rich protein 3 | -0.00553069 |
| SPART | spartin | -0.00552977 |
| HOXC4 | homeobox C4 | -0.00552905 |
| FCGBP | Fc fragment of IgG binding protein | -0.00552358 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00550405 |
| ESR1 | estrogen receptor 1 | -0.00548842 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00546677 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00544504 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00542414 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00541439 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00541324 |
| VLDLR | very low density lipoprotein receptor | -0.00541101 |
| MMRN1 | multimerin 1 | -0.00539611 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00539568 |
| MUC4 | mucin 4, cell surface associated | -0.00538176 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00536967 |
| CD320 | CD320 molecule | -0.00535712 |
| RBPMS | RNA binding protein with multiple splicing | -0.00535693 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00533627 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0053282 |
| WASF1 | WAS protein family, member 1 | -0.00531477 |
| HOXB2 | homeobox B2 | -0.00530706 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00530573 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00529777 |
| EMP3 | epithelial membrane protein 3 | -0.00528566 |
| TSPYL5 | TSPY-like 5 | -0.00524269 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0052413 |
| PMP22 | peripheral myelin protein 22 | -0.00522193 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0052101 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00520287 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00520033 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00516228 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | -0.00516129 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00515243 |
| PKP1 | plakophilin 1 | -0.00515132 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00514952 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00514692 |
| CRNN | cornulin | -0.00514545 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00514517 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00512639 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00512625 |
| AEBP1 | AE binding protein 1 | -0.00512585 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00511821 |
| MYL9 | myosin, light chain 9, regulatory | -0.00511131 |
| MYO5C | myosin VC | -0.00510283 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00509381 |
| PMEL | premelanosome protein | -0.00508135 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00506139 |
| ODC1 | ornithine decarboxylase 1 | -0.00506074 |
| ELANE | elastase, neutrophil expressed | -0.00502274 |
| PLCL2 | phospholipase C-like 2 | -0.00500281 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.004985 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.00497974 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00495778 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00494576 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | -0.00492385 |
| TMPRSS11D | transmembrane protease, serine 11D | -0.00491655 |
| LIN28A | lin-28 homolog A (C. elegans) | -0.00491277 |
| TMEM164 | transmembrane protein 164 | -0.00490452 |
| IRX5 | iroquois homeobox 5 | -0.00490449 |
| RSBN1 | round spermatid basic protein 1 | -0.00490025 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00488725 |
| PLBD1 | phospholipase B domain containing 1 | -0.00487985 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00487968 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00486229 |
| SVIL | supervillin | -0.00485759 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00485058 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | -0.00484995 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00484665 |
| NID2 | nidogen 2 (osteonidogen) | -0.00484177 |
| VPREB3 | pre-B lymphocyte 3 | -0.00483947 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00482999 |
| GUCY2C | guanylate cyclase 2C | -0.00482818 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00481795 |
| MMP9 | matrix metallopeptidase 9 | -0.00480101 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00479004 |
| RPL13A | ribosomal protein L13a | -0.00475961 |
| LRRC8B | leucine rich repeat containing 8 family, member B | -0.00474842 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00473273 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00473202 |
| SUSD4 | sushi domain containing 4 | -0.00472943 |
| LTA4H | leukotriene A4 hydrolase | -0.00471652 |
| FADS1 | fatty acid desaturase 1 | -0.00470952 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00470786 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0047069 |
| ACVR1B | activin A receptor, type IB | -0.00470505 |
| PIMREG | PICALM interacting mitotic regulator | -0.0046919 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00469054 |
| SUN2 | Sad1 and UNC84 domain containing 2 | -0.0046893 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00467387 |
| RTN3 | reticulon 3 | -0.00466454 |
| CTSA | cathepsin A | -0.00464794 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.00464088 |
| STEAP1B | STEAP family member 1B | -0.00462849 |
| SLC22A8 | solute carrier family 22 (organic anion transporter), member 8 | -0.0046203 |
| HOXB7 | homeobox B7 | -0.00459283 |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | -0.00458431 |
| NMB | neuromedin B | -0.0045843 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00458233 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00458225 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0045736 |
| APMAP | adipocyte plasma membrane associated protein | -0.00457138 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.00457111 |
| ECHS1 | enoyl CoA hydratase, short chain, 1, mitochondrial | -0.00456493 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | -0.0045576 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.00454944 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00454849 |
| AZU1 | azurocidin 1 | -0.00453716 |
| DUOX2 | dual oxidase 2 | -0.00453503 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00453011 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00452898 |
| FOXL2 | forkhead box L2 | -0.00452896 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00450468 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00449692 |
| WDR3 | WD repeat domain 3 | -0.00449627 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | -0.0044945 |
| MT1G | metallothionein 1G | -0.00448863 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00448728 |
| PRR11 | proline rich 11 | -0.00448439 |
| KLHDC8A | kelch domain containing 8A | -0.00448115 |
| CDCP1 | CUB domain containing protein 1 | -0.00446039 |
| ZNF721 | zinc finger protein 721 | -0.00444632 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00444117 |
| BUB3 | BUB3 mitotic checkpoint protein | -0.00443997 |
| VIM | vimentin | -0.00443428 |
| BCR | breakpoint cluster region | -0.00442202 |
| TMEM47 | transmembrane protein 47 | -0.0044199 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.00440941 |
| TGFA | transforming growth factor, alpha | -0.0043963 |
| ECE1 | endothelin converting enzyme 1 | -0.00439072 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0043796 |
| DCLK1 | doublecortin-like kinase 1 | -0.00437052 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00436962 |
| DUSP1 | dual specificity phosphatase 1 | -0.00436586 |
| ACO1 | aconitase 1, soluble | -0.00436117 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -0.0043563 |
| CENPM | centromere protein M | -0.00435463 |
