MAP4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description microtubule-associated protein 4|The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] (NCBI Entrez Gene Database, 4134)
External Link https://ncbi.nlm.nih.gov/gene/4134
Similar Terms
Downloads & Tools

Genes

500 genes differentially expressed following the MAP4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 0.0269557
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0266689
ANXA3 annexin A3 0.018433
SCGB2A1 secretoglobin, family 2A, member 1 0.017439
GATA6 GATA binding protein 6 0.0166497
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.0159838
PLAT plasminogen activator, tissue 0.0155551
COL4A5 collagen, type IV, alpha 5 0.015538
AOC1 amine oxidase, copper containing 1 0.0148098
KLK11 kallikrein-related peptidase 11 0.0147727
DSP desmoplakin 0.0145155
NVL nuclear VCP-like 0.0142883
TFF1 trefoil factor 1 0.0142387
GREB1 growth regulation by estrogen in breast cancer 1 0.0141106
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0140019
LCN2 lipocalin 2 0.0139835
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.0137332
CDCA4 cell division cycle associated 4 0.0137024
SCGB1D2 secretoglobin, family 1D, member 2 0.0136335
HOXB6 homeobox B6 0.0132916
ZNF589 zinc finger protein 589 0.0132384
MLPH melanophilin 0.0132001
TOX3 TOX high mobility group box family member 3 0.0128526
NUSAP1 nucleolar and spindle associated protein 1 0.0128106
KDM5D lysine (K)-specific demethylase 5D 0.0127455
RB1 retinoblastoma 1 0.0127427
STXBP6 syntaxin binding protein 6 (amisyn) 0.0125844
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.0125062
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0123916
HMGB2 high mobility group box 2 0.0123207
MYB v-myb avian myeloblastosis viral oncogene homolog 0.012091
GUSBP3 glucuronidase, beta pseudogene 3 0.0119284
ESR1 estrogen receptor 1 0.0119213
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.0118548
HSPA2 heat shock 70kDa protein 2 0.0116129
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0115052
MDK midkine (neurite growth-promoting factor 2) 0.0114214
TCF21 transcription factor 21 0.0113742
SORD sorbitol dehydrogenase 0.011267
PKP2 plakophilin 2 0.0112627
HOXB2 homeobox B2 0.0111558
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0111493
ASRGL1 asparaginase like 1 0.011099
NEFH neurofilament, heavy polypeptide 0.0110714
ERAP2 endoplasmic reticulum aminopeptidase 2 0.0110018
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.0109594
FLNA filamin A, alpha 0.0109549
PCNA proliferating cell nuclear antigen 0.01094
C7 complement component 7 0.0108788
EHF ets homologous factor 0.0108712
MEIS1 Meis homeobox 1 0.0108429
AOX1 aldehyde oxidase 1 0.0108002
ACP3 acid phosphatase 3 0.0106943
PDZRN3 PDZ domain containing ring finger 3 0.0105976
ATP10B ATPase, class V, type 10B 0.0105635
ABHD4 abhydrolase domain containing 4 0.0105478
S100A9 S100 calcium binding protein A9 0.0104569
PYCARD PYD and CARD domain containing 0.0103625
MATN2 matrilin 2 0.0102728
EYA2 EYA transcriptional coactivator and phosphatase 2 0.0102479
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.0102293
OLFM4 olfactomedin 4 0.0101836
IVNS1ABP influenza virus NS1A binding protein 0.0101664
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.0101617
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0100941
TPM4 tropomyosin 4 0.00998038
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00996523
NPR3 natriuretic peptide receptor 3 0.00995038
SHTN1 shootin 1 0.00993331
ESRP1 epithelial splicing regulatory protein 1 0.00991832
LPXN leupaxin 0.0099009
KLK10 kallikrein-related peptidase 10 0.00983754
KLK8 kallikrein-related peptidase 8 0.00983556
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00977905
MEIS2 Meis homeobox 2 0.0097649
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00973771
FERMT1 fermitin family member 1 0.00966145
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00956739
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00956492
LAMP5 lysosomal-associated membrane protein family, member 5 0.00951555
FXYD3 FXYD domain containing ion transport regulator 3 0.00949444
BST2 bone marrow stromal cell antigen 2 0.00945649
MYRF myelin regulatory factor 0.0094229
ZSCAN31 zinc finger and SCAN domain containing 31 0.00941666
STON1 stonin 1 0.00940644
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00936032
MMP12 matrix metallopeptidase 12 0.00929502
TYMS thymidylate synthetase 0.00928934
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00928842
CHN2 chimerin 2 0.00928417
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00927113
WLS wntless Wnt ligand secretion mediator 0.00926698
LMCD1 LIM and cysteine-rich domains 1 0.0092589
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00918185
OXA1L oxidase (cytochrome c) assembly 1-like 0.00917656
SLC44A4 solute carrier family 44, member 4 0.00914901
XK X-linked Kx blood group 0.00909227
GCA grancalcin, EF-hand calcium binding protein 0.00904117
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.00898902
S100A7 S100 calcium binding protein A7 0.00898026
GAS1 growth arrest-specific 1 0.00897284
GUCY2C guanylate cyclase 2C 0.00895057
WNT5A wingless-type MMTV integration site family, member 5A 0.00892667
LY86 lymphocyte antigen 86 0.00891076
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00890983
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00889236
KLHL23 kelch-like family member 23 0.00888401
S100A14 S100 calcium binding protein A14 0.00885512
KCTD12 potassium channel tetramerization domain containing 12 0.00884515
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00882048
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00881975
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00878268
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00876817
MAL mal, T-cell differentiation protein 0.00876452
VLDLR very low density lipoprotein receptor 0.00876248
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00872088
TPM2 tropomyosin 2 (beta) 0.00868341
CLDN8 claudin 8 0.00867483
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00866698
ADM adrenomedullin 0.0086279
COL4A6 collagen, type IV, alpha 6 0.00860002
PRDX2 peroxiredoxin 2 0.00859652
FST follistatin 0.00859312
AAMDC adipogenesis associated, Mth938 domain containing 0.00858178
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00856725
DEFB1 defensin, beta 1 0.00852606
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.0084824
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00836749
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00835725
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00833419
CTSC cathepsin C 0.00831454
DACH1 dachshund family transcription factor 1 0.00830025
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00826794
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00823951
PODXL podocalyxin-like 0.00821531
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00819747
TGFBR3 transforming growth factor, beta receptor III 0.00819674
OSR2 odd-skipped related transciption factor 2 0.00819202
COLEC11 collectin sub-family member 11 0.00818903
GREM1 gremlin 1, DAN family BMP antagonist 0.00818689
TFF3 trefoil factor 3 (intestinal) 0.00813689
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00813587
CPVL carboxypeptidase, vitellogenic-like 0.00811366
IFI27 interferon, alpha-inducible protein 27 0.00809685
STXBP2 syntaxin binding protein 2 0.00804275
EMP3 epithelial membrane protein 3 0.00803192
CD99 CD99 molecule 0.0080275
KLK7 kallikrein-related peptidase 7 0.00802534
DCK deoxycytidine kinase 0.00800296
ADCY7 adenylate cyclase 7 0.00799249
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00798475
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00797621
ACKR3 atypical chemokine receptor 3 0.00797203
SH3YL1 SH3 and SYLF domain containing 1 0.00796072
JCHAIN joining chain of multimeric IgA and IgM 0.00796022
CAPN3 calpain 3, (p94) 0.00795055
ADA adenosine deaminase 0.00789077
SIDT1 SID1 transmembrane family, member 1 0.00785892
LGALS1 lectin, galactoside-binding, soluble, 1 0.00783867
ALAD aminolevulinate dehydratase 0.00782039
AHNAK2 AHNAK nucleoprotein 2 0.00781911
SPART spartin 0.00780662
S100A12 S100 calcium binding protein A12 0.0078037
EPCAM epithelial cell adhesion molecule 0.007788
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00774919
PALLD palladin, cytoskeletal associated protein 0.00774212
SFRP1 secreted frizzled-related protein 1 0.00772482
FZD3 frizzled class receptor 3 0.00772033
KLK6 kallikrein-related peptidase 6 0.00771563
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00771303
VCAN versican 0.00769361
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0076907
CALB1 calbindin 1, 28kDa 0.00766834
SOX17 SRY (sex determining region Y)-box 17 0.00766432
NMU neuromedin U 0.00765144
AMIGO2 adhesion molecule with Ig-like domain 2 0.00763925
PRKCQ protein kinase C, theta 0.0076344
PLCB4 phospholipase C, beta 4 0.00762343
S100A10 S100 calcium binding protein A10 0.00760459
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.0075976
ZNF426 zinc finger protein 426 0.00755802
GALC galactosylceramidase 0.00750776
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00746883
SRPX sushi-repeat containing protein, X-linked 0.00746729
HIST3H2A histone cluster 3, H2a 0.00745906
TMPRSS4 transmembrane protease, serine 4 0.00741643
EPHB2 EPH receptor B2 0.00741465
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00741215
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00740599
HIST1H2BD histone cluster 1, H2bd 0.00738666
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00738655
MCAM melanoma cell adhesion molecule 0.00736583
THBS1 thrombospondin 1 0.00735813
ZNF185 zinc finger protein 185 (LIM domain) 0.00732641
ODC1 ornithine decarboxylase 1 0.00730529
IL10RB interleukin 10 receptor, beta 0.00730075
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00727377
NUBPL nucleotide binding protein-like 0.00726944
RNASE6 ribonuclease, RNase A family, k6 0.00726311
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00725498
PNMA8A PNMA family member 8A 0.00720345
MAP2K6 mitogen-activated protein kinase kinase 6 0.00718571
SPATA7 spermatogenesis associated 7 0.00717343
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00716295
HBB hemoglobin, beta 0.00712579
AK4 adenylate kinase 4 0.00711167
HIST1H2AC histone cluster 1, H2ac 0.00707863
DAAM1 dishevelled associated activator of morphogenesis 1 0.00706373
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00706331
GPX1 glutathione peroxidase 1 0.00704933
RAB25 RAB25, member RAS oncogene family 0.00703587
CLEC11A C-type lectin domain family 11, member A 0.00702865
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00701041
SDC1 syndecan 1 0.00700498
ARCN1 archain 1 0.00699847
CFI complement factor I 0.00697002
NSG1 neuron specific gene family member 1 0.00695595
HSDL2 hydroxysteroid dehydrogenase like 2 0.0069349
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00692598
TBX3 T-box 3 0.00691543
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0069129
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00690037
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00689417
H1-10 H1.10 linker histone 0.00689381
FOXL2 forkhead box L2 0.00689315
TP53I3 tumor protein p53 inducible protein 3 0.00687149
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00686095
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00684904
FBP1 fructose-1,6-bisphosphatase 1 0.00682407
IER2 immediate early response 2 0.0068182
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0068059
S100A8 S100 calcium binding protein A8 0.00680375
TMEM63A transmembrane protein 63A 0.00680264
SNX17 sorting nexin 17 0.00680086
TNNT1 troponin T type 1 (skeletal, slow) 0.00679541
VANGL1 VANGL planar cell polarity protein 1 0.00679415
SGMS1 sphingomyelin synthase 1 0.00677938
ECI2 enoyl-CoA delta isomerase 2 0.00677296
LEFTY1 left-right determination factor 1 0.00677056
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.00675038
GJA1 gap junction protein, alpha 1, 43kDa 0.00674222
VSNL1 visinin-like 1 0.00673752
CERS6 ceramide synthase 6 0.00672785
HOXB5 homeobox B5 0.00672328
NPEPL1 aminopeptidase-like 1 0.00670667
SCGB2A2 secretoglobin, family 2A, member 2 0.00669293
DMXL1 Dmx-like 1 0.00668508
CRABP2 cellular retinoic acid binding protein 2 0.00668299
NREP neuronal regeneration related protein 0.00667466
LMNB1 lamin B1 0.00666866

decreased expression

Symbol Name Standardized Value
CHP1 calcineurin-like EF-hand protein 1 -0.0337389
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.0248889
MEF2C myocyte enhancer factor 2C -0.0182881
A2M alpha-2-macroglobulin -0.0171463
SIRT3 sirtuin 3 -0.0165798
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0160359
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0153094
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0144067
TLCD3A TLC domain containing 3A -0.0143395
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0124117
MGP matrix Gla protein -0.0123818
ASPN asporin -0.0123527
GAL galanin/GMAP prepropeptide -0.0123371
NNMT nicotinamide N-methyltransferase -0.0122734
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0117293
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.011616
TSPYL5 TSPY-like 5 -0.0115713
ADGRF5 adhesion G protein-coupled receptor F5 -0.0115333
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.0114201
CBX6 chromobox homolog 6 -0.0113371
XIC X chromosome inactivation center -0.0113004
STEAP3 STEAP family member 3, metalloreductase -0.0111594
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.0110007
SCGN secretagogin, EF-hand calcium binding protein -0.010923
PCDH9 protocadherin 9 -0.0107509
PLXND1 plexin D1 -0.0106575
HOPX HOP homeobox -0.0105083
BEX1 brain expressed, X-linked 1 -0.0102432
FKBP11 FK506 binding protein 11, 19 kDa -0.0101765
LDB2 LIM domain binding 2 -0.0101723
TXNDC9 thioredoxin domain containing 9 -0.0101548
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0101274
SLC38A1 solute carrier family 38, member 1 -0.0100626
ADGRG2 adhesion G protein-coupled receptor G2 -0.00994127
AKR1C1 aldo-keto reductase family 1, member C1 -0.00994075
TLR4 toll-like receptor 4 -0.00984785
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.0097752
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00969759
MRTFB myocardin related transcription factor B -0.009671
SNAP25 synaptosomal-associated protein, 25kDa -0.00958556
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00954765
POSTN periostin, osteoblast specific factor -0.00953374
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00949218
ABHD6 abhydrolase domain containing 6 -0.0094834
MET MET proto-oncogene, receptor tyrosine kinase -0.0094603
THBS4 thrombospondin 4 -0.00943356
KRT17 keratin 17, type I -0.00940179
GARS1 glycyl-tRNA synthetase 1 -0.00938532
SLPI secretory leukocyte peptidase inhibitor -0.00936285
BMP2 bone morphogenetic protein 2 -0.00927947
COL2A1 collagen, type II, alpha 1 -0.00921986
OLFM1 olfactomedin 1 -0.00903638
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.00901714
CP ceruloplasmin (ferroxidase) -0.00890848
PLS3 plastin 3 -0.00890578
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00889339
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00887443
FGFR1 fibroblast growth factor receptor 1 -0.00886965
GNAS GNAS complex locus -0.00884108
HYOU1 hypoxia up-regulated 1 -0.0088229
BGN biglycan -0.00880787
FAM3C family with sequence similarity 3, member C -0.00876423
IL32 interleukin 32 -0.00875373
RTN1 reticulon 1 -0.00874534
AKR1C2 aldo-keto reductase family 1, member C2 -0.00871726
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00869896
POU2AF1 POU class 2 associating factor 1 -0.0086917
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00866097
FOXG1 forkhead box G1 -0.00861935
DYNLL1 dynein, light chain, LC8-type 1 -0.00857049
XYLT1 xylosyltransferase I -0.0085136
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.00847832
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -0.00847045
SORBS2 sorbin and SH3 domain containing 2 -0.00847002
TMED5 transmembrane emp24 protein transport domain containing 5 -0.00840676
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00840481
GSN gelsolin -0.00837662
MMP7 matrix metallopeptidase 7 -0.00836056
FUCA1 fucosidase, alpha-L- 1, tissue -0.00833595
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00825008
TM4SF4 transmembrane 4 L six family member 4 -0.00822178
EIF5B eukaryotic translation initiation factor 5B -0.00816358
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -0.00814296
CLU clusterin -0.00809802
MT1M metallothionein 1M -0.00807761
ARMCX3 armadillo repeat containing, X-linked 3 -0.00806225
HSPA1A heat shock 70kDa protein 1A -0.00803186
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00793685
LOC283683 uncharacterized LOC283683 -0.00790995
PCDH17 protocadherin 17 -0.00788923
GMFG glia maturation factor, gamma -0.00788868
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00785753
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00783733
MMP9 matrix metallopeptidase 9 -0.00783569
DCLK1 doublecortin-like kinase 1 -0.00779988
CA2 carbonic anhydrase II -0.00779825
SEC63 SEC63 homolog (S. cerevisiae) -0.00775999
SYN1 synapsin I -0.00774758
OLFML2B olfactomedin-like 2B -0.00771144
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 -0.0077021
ZBTB16 zinc finger and BTB domain containing 16 -0.00770206
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00768402
FGA fibrinogen alpha chain -0.00766915
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00766823
SCRG1 stimulator of chondrogenesis 1 -0.00763788
ACP2 acid phosphatase 2, lysosomal -0.00753847
FASN fatty acid synthase -0.00751568
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -0.00751496
WEE1 WEE1 G2 checkpoint kinase -0.0075079
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00747164
JAKMIP2 janus kinase and microtubule interacting protein 2 -0.00743
CNN3 calponin 3, acidic -0.00742673
APOD apolipoprotein D -0.00740345
PMM2 phosphomannomutase 2 -0.00739805
SDC2 syndecan 2 -0.00739724
CRMP1 collapsin response mediator protein 1 -0.00736959
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00732493
IL13RA2 interleukin 13 receptor, alpha 2 -0.00731077
IGFBP4 insulin-like growth factor binding protein 4 -0.00730812
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.0072832
MXRA7 matrix-remodelling associated 7 -0.00721536
CBS cystathionine-beta-synthase -0.0072107
RBPMS RNA binding protein with multiple splicing -0.00717077
CALCRL calcitonin receptor-like -0.00715153
FN1 fibronectin 1 -0.0071257
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.00709265
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00706782
TCF4 transcription factor 4 -0.00703901
CTSE cathepsin E -0.00702217
USP47 ubiquitin specific peptidase 47 -0.00700517
CHI3L2 chitinase 3-like 2 -0.00698997
ABHD2 abhydrolase domain containing 2 -0.00696214
CPA3 carboxypeptidase A3 (mast cell) -0.00693772
PFN2 profilin 2 -0.00693422
CLEC2B C-type lectin domain family 2, member B -0.00693202
FABP7 fatty acid binding protein 7, brain -0.00692159
WDR19 WD repeat domain 19 -0.00689223
MEOX2 mesenchyme homeobox 2 -0.00687257
GPX4 glutathione peroxidase 4 -0.00687177
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00683484
EIF5A eukaryotic translation initiation factor 5A -0.00682995
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00681779
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00681715
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00681021
MFSD10 major facilitator superfamily domain containing 10 -0.00678516
ELN elastin -0.00677461
BCAP31 B-cell receptor-associated protein 31 -0.00675482
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00674068
MGLL monoglyceride lipase -0.00672569
AIM2 absent in melanoma 2 -0.00671763
PRR14 proline rich 14 -0.00671165
TM2D3 TM2 domain containing 3 -0.0066846
PRR7 proline rich 7 (synaptic) -0.00667482
CADM1 cell adhesion molecule 1 -0.00666069
NFE2L1 nuclear factor, erythroid 2-like 1 -0.00665445
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00664213
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.00661942
EGR2 early growth response 2 -0.00661906
PAX5 paired box 5 -0.00658772
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00658714
PRKD3 protein kinase D3 -0.00658537
SUSD5 sushi domain containing 5 -0.00658065
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.00657163
GUSB glucuronidase, beta -0.0065586
RAB13 RAB13, member RAS oncogene family -0.00655715
ITGA10 integrin, alpha 10 -0.00655545
ORM1 orosomucoid 1 -0.00655247
NPTXR neuronal pentraxin receptor -0.00655154
TBL1X transducin (beta)-like 1X-linked -0.0065306
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.00652394
ELL2 elongation factor, RNA polymerase II, 2 -0.0065116
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.00651061
EMP1 epithelial membrane protein 1 -0.00650356
SOX11 SRY (sex determining region Y)-box 11 -0.00648071
PCDHGA3 protocadherin gamma subfamily A, 3 -0.00647626
PTN pleiotrophin -0.00646144
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00644896
PPIF peptidylprolyl isomerase F -0.00642674
GCC2 GRIP and coiled-coil domain containing 2 -0.00641426
RFTN1 raftlin, lipid raft linker 1 -0.00636912
MIA melanoma inhibitory activity -0.00636879
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -0.00636541
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -0.006355
SCN3A sodium channel, voltage gated, type III alpha subunit -0.00635364
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.00635122
TESC tescalcin -0.00634151
NRGN neurogranin (protein kinase C substrate, RC3) -0.00634008
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -0.00632743
PGD phosphogluconate dehydrogenase -0.00630785
LY6E lymphocyte antigen 6 complex, locus E -0.00630668
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.00629856
AMDHD2 amidohydrolase domain containing 2 -0.00628244
HMGN3 high mobility group nucleosomal binding domain 3 -0.00627107
RETREG1 reticulophagy regulator 1 -0.00626815
RGS5 regulator of G-protein signaling 5 -0.00626388
WBP5 WW domain binding protein 5 -0.00625566
TM4SF1 transmembrane 4 L six family member 1 -0.00625071
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -0.00624793
VCAM1 vascular cell adhesion molecule 1 -0.00624699
CCL4 chemokine (C-C motif) ligand 4 -0.00624168
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00622931
SOD3 superoxide dismutase 3, extracellular -0.00622925
TSPAN7 tetraspanin 7 -0.00622748
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00622293
FABP4 fatty acid binding protein 4, adipocyte -0.00622098
SFTPC surfactant protein C -0.00621046
CSTB cystatin B (stefin B) -0.0062069
ABLIM3 actin binding LIM protein family, member 3 -0.00618439
EDNRB endothelin receptor type B -0.00618407
GOLIM4 golgi integral membrane protein 4 -0.00618326
ELMO1 engulfment and cell motility 1 -0.00618172
TNK2 tyrosine kinase, non-receptor, 2 -0.00618068
NEFM neurofilament, medium polypeptide -0.00617276
NPC1 Niemann-Pick disease, type C1 -0.00616509
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 -0.00616427
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -0.00615905
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00615315
SLC35G2 solute carrier family 35, member G2 -0.00613258
TFF2 trefoil factor 2 -0.00612464
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00612342
MYBPC1 myosin binding protein C, slow type -0.00611679
CES1 carboxylesterase 1 -0.0061162
NRN1 neuritin 1 -0.00610356
GSPT2 G1 to S phase transition 2 -0.0060874
TP63 tumor protein p63 -0.00608144
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00607827
FGF14 fibroblast growth factor 14 -0.00607499
EPAS1 endothelial PAS domain protein 1 -0.00606451
ICAM2 intercellular adhesion molecule 2 -0.00604395
LMNA lamin A/C -0.00604117
MELK maternal embryonic leucine zipper kinase -0.00604094
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.00601614
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00601352
TRAF3 TNF receptor-associated factor 3 -0.0060124
ANGPT2 angiopoietin 2 -0.00601113
SIGLEC15 sialic acid binding Ig-like lectin 15 -0.00599618
GOLM1 golgi membrane protein 1 -0.00598924
SDF2L1 stromal cell-derived factor 2-like 1 -0.00598388
ANGPTL4 angiopoietin-like 4 -0.00598009
GEM GTP binding protein overexpressed in skeletal muscle -0.00597592
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00597489
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -0.00596438
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.00595633
SCARB2 scavenger receptor class B, member 2 -0.00595133
ZNF281 zinc finger protein 281 -0.00594953
DUSP5 dual specificity phosphatase 5 -0.00594685
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -0.00594139
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00589325
NFIB nuclear factor I/B -0.00589027
RXRA retinoid X receptor, alpha -0.00588785