MAP4K5_knockdown_199_GSE61497 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE61497
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Genes

600 genes differentially expressed following the MAP4K5_knockdown_199_GSE61497 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
SMOC2 SPARC related modular calcium binding 2 4.31685
RTP2 receptor (chemosensory) transporter protein 2 4.00882
FAM173B family with sequence similarity 173, member B 3.77802
SMTN smoothelin 3.73373
GDE1 glycerophosphodiester phosphodiesterase 1 3.53004
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 3.32891
FTH1 ferritin, heavy polypeptide 1 3.32717
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 3.30261
DUX1 double homeobox 1 3.25654
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 3.10364
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 3.10219
MESDC2 mesoderm development candidate 2 3.10013
JTB jumping translocation breakpoint 3.09978
AKR1C4 aldo-keto reductase family 1, member C4 3.09316
GYPE glycophorin E (MNS blood group) 3.03177
ATL3 atlastin GTPase 3 3.00819
WDR37 WD repeat domain 37 3.00072
TIMP2 TIMP metallopeptidase inhibitor 2 2.98469
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 2.96326
PNPT1 polyribonucleotide nucleotidyltransferase 1 2.82736
NRIP3 nuclear receptor interacting protein 3 2.78441
TBC1D2 TBC1 domain family, member 2 2.76883
REXO2 RNA exonuclease 2 2.76035
TMIGD1 transmembrane and immunoglobulin domain containing 1 2.75988
TCEAL1 transcription elongation factor A (SII)-like 1 2.7144
CREB3L2 cAMP responsive element binding protein 3-like 2 2.70172
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 2.68287
MAGEA1 melanoma antigen family A1 2.61044
KEL Kell blood group, metallo-endopeptidase 2.60197
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.55165
PTRH2 peptidyl-tRNA hydrolase 2 2.51875
MCFD2 multiple coagulation factor deficiency 2 2.49289
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 2.46065
PRSS35 protease, serine, 35 2.42774
TPRG1L tumor protein p63 regulated 1-like 2.42101
WWC1 WW and C2 domain containing 1 2.41986
TRIM22 tripartite motif containing 22 2.39288
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.39178
MCOLN1 mucolipin 1 2.38994
ASB6 ankyrin repeat and SOCS box containing 6 2.38769
UBE2D2 ubiquitin-conjugating enzyme E2D 2 2.38716
CLDN10 claudin 10 2.36598
THAP7 THAP domain containing 7 2.35564
PRDM2 PR domain containing 2, with ZNF domain 2.35446
MYOCD myocardin 2.35254
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.33932
VRK3 vaccinia related kinase 3 2.32589
ESR1 estrogen receptor 1 2.30525
PNP purine nucleoside phosphorylase 2.29705
ASRGL1 asparaginase like 1 2.29688
PPAP2B phosphatidic acid phosphatase type 2B 2.29366
PNMAL1 paraneoplastic Ma antigen family-like 1 2.28281
DNASE1L1 deoxyribonuclease I-like 1 2.27805
CCDC137 coiled-coil domain containing 137 2.26648
PRICKLE1 prickle homolog 1 (Drosophila) 2.2579
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 2.2557
C1ORF122 chromosome 1 open reading frame 122 2.25448
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 2.2526
SIK2 salt-inducible kinase 2 2.24892
DTWD1 DTW domain containing 1 2.23596
MAVS mitochondrial antiviral signaling protein 2.20017
BAG1 BCL2-associated athanogene 2.20002
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B 2.19747
TMEM184B transmembrane protein 184B 2.19563
HIST1H1C histone cluster 1, H1c 2.18649
NAF1 nuclear assembly factor 1 ribonucleoprotein 2.18374
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 2.1634
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2.14773
SYNJ2BP synaptojanin 2 binding protein 2.13397
GIPC2 GIPC PDZ domain containing family, member 2 2.11305
SERINC2 serine incorporator 2 2.10041
RGS4 regulator of G-protein signaling 4 2.10017
TH tyrosine hydroxylase 2.09367
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2.07248
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 2.06033
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 2.04948
ASMT acetylserotonin O-methyltransferase 2.03819
GLB1L2 galactosidase, beta 1-like 2 2.03605
SF3B2 splicing factor 3b, subunit 2, 145kDa 2.02965
NCKAP1L NCK-associated protein 1-like 2.02458
C10ORF111 chromosome 10 open reading frame 111 1.99636
C9ORF69 chromosome 9 open reading frame 69 1.99317
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 1.99296
BEST3 bestrophin 3 1.98786
MTF1 metal-regulatory transcription factor 1 1.96469
UNC5A unc-5 homolog A (C. elegans) 1.95868
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 1.95537
TYRP1 tyrosinase-related protein 1 1.9514
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.94627
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 1.94531
TARBP2 TAR (HIV-1) RNA binding protein 2 1.93906
REP15 RAB15 effector protein 1.93573
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 1.93146
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 1.92906
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.90837
F11R F11 receptor 1.9048
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 1.89973
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 1.89628
MACF1 microtubule-actin crosslinking factor 1 1.88942
GGT6 gamma-glutamyltransferase 6 1.88136
CHPF chondroitin polymerizing factor 1.8797
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.86929
C1ORF68 chromosome 1 open reading frame 68 1.85244
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 1.85208
GPR107 G protein-coupled receptor 107 1.85115
LRRN3 leucine rich repeat neuronal 3 1.84246
FAM71B family with sequence similarity 71, member B 1.83872
PTPRR protein tyrosine phosphatase, receptor type, R 1.83677
RASAL2 RAS protein activator like 2 1.83634
SLC25A48 solute carrier family 25, member 48 1.82936
COBL cordon-bleu WH2 repeat protein 1.82707
TMEM223 transmembrane protein 223 1.82385
USP1 ubiquitin specific peptidase 1 1.82214
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 1.82136
NENF neudesin neurotrophic factor 1.8193
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.81599
PARD6A par-6 family cell polarity regulator alpha 1.8039
DUSP3 dual specificity phosphatase 3 1.79834
NOL6 nucleolar protein 6 (RNA-associated) 1.79328
MYH15 myosin, heavy chain 15 1.79264
FGA fibrinogen alpha chain 1.78535
RGS17 regulator of G-protein signaling 17 1.78443
ERAS ES cell expressed Ras 1.77844
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 1.77589
AUTS2 autism susceptibility candidate 2 1.76754
GJC1 gap junction protein, gamma 1, 45kDa 1.76751
SORCS3 sortilin-related VPS10 domain containing receptor 3 1.76465
MAP3K9 mitogen-activated protein kinase kinase kinase 9 1.7595
NALCN sodium leak channel, non selective 1.75838
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 1.75468
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.74866
ZBTB32 zinc finger and BTB domain containing 32 1.74804
CCDC57 coiled-coil domain containing 57 1.71493
CD6 CD6 molecule 1.71189
SDHAF2 succinate dehydrogenase complex assembly factor 2 1.71133
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3 1.7077
DNER delta/notch-like EGF repeat containing 1.70314
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.69746
LDLRAD2 low density lipoprotein receptor class A domain containing 2 1.69432
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 1.69415
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.68735
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 1.67251
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 1.67184
EPHB2 EPH receptor B2 1.6608
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 1.65249
TGOLN2 trans-golgi network protein 2 1.64727
EPHA1 EPH receptor A1 1.64391
ZNF271P zinc finger protein 271, pseudogene 1.63924
LUZP2 leucine zipper protein 2 1.63285
PDZD7 PDZ domain containing 7 1.63231
SFMBT1 Scm-like with four mbt domains 1 1.63168
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.63149
MAGEC2 melanoma antigen family C2 1.62222
MRPL34 mitochondrial ribosomal protein L34 1.61462
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.60361
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 1.59901
DOCK8 dedicator of cytokinesis 8 1.59689
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.59422
AGER advanced glycosylation end product-specific receptor 1.59375
MMP13 matrix metallopeptidase 13 1.59267
FAM171A1 family with sequence similarity 171, member A1 1.5896
CYB5D1 cytochrome b5 domain containing 1 1.58888
SH3GL1 SH3-domain GRB2-like 1 1.58329
CSF3 colony stimulating factor 3 (granulocyte) 1.57519
PKNOX1 PBX/knotted 1 homeobox 1 1.5695
MRPL49 mitochondrial ribosomal protein L49 1.56603
TMEM167A transmembrane protein 167A 1.56175
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1.55723
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 1.555
HIST1H2BK histone cluster 1, H2bk 1.55211
INPP5J inositol polyphosphate-5-phosphatase J 1.54504
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 1.54427
ZNF267 zinc finger protein 267 1.54306
RPL17 ribosomal protein L17 1.5407
EBNA1BP2 EBNA1 binding protein 2 1.53031
COMMD5 COMM domain containing 5 1.51979
TEX9 testis expressed 9 1.50193
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.50158
CD209 CD209 molecule 1.50157
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.49713
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 1.49629
RGL1 ral guanine nucleotide dissociation stimulator-like 1 1.49454
COPS3 COP9 signalosome subunit 3 1.49279
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 1.48997
NMT1 N-myristoyltransferase 1 1.48802
HIST1H2BG histone cluster 1, H2bg 1.48434
RBM39 RNA binding motif protein 39 1.48196
CIB1 calcium and integrin binding 1 (calmyrin) 1.47982
CLIC6 chloride intracellular channel 6 1.47775
LZIC leucine zipper and CTNNBIP1 domain containing 1.47034
ARRB2 arrestin, beta 2 1.46972
LAPTM5 lysosomal protein transmembrane 5 1.46528
SPOPL speckle-type POZ protein-like 1.46215
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.46195
C7ORF43 chromosome 7 open reading frame 43 1.4603
SAMD1 sterile alpha motif domain containing 1 1.45497
MAGEB18 melanoma antigen family B18 1.45391
TMCO1 transmembrane and coiled-coil domains 1 1.45327
SEC11C SEC11 homolog C (S. cerevisiae) 1.45272
EBF2 early B-cell factor 2 1.45145
LRP2 low density lipoprotein receptor-related protein 2 1.45055
DGAT2 diacylglycerol O-acyltransferase 2 1.45015
C9ORF142 chromosome 9 open reading frame 142 1.44033
PRDM15 PR domain containing 15 1.43904
SKAP2 src kinase associated phosphoprotein 2 1.43826
AQP3 aquaporin 3 (Gill blood group) 1.4339
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 1.43223
KRT9 keratin 9, type I 1.43043
USH2A Usher syndrome 2A (autosomal recessive, mild) 1.42766
LHX1 LIM homeobox 1 1.42675
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 1.42343
WFDC8 WAP four-disulfide core domain 8 1.41988
WDR33 WD repeat domain 33 1.41803
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.41723
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 1.41676
SPDYA speedy/RINGO cell cycle regulator family member A 1.41606
CCNK cyclin K 1.41547
ABHD12 abhydrolase domain containing 12 1.41451
KYNU kynureninase 1.41144
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.40922
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.40098
ZDHHC16 zinc finger, DHHC-type containing 16 1.40041
TFAM transcription factor A, mitochondrial 1.3997
GTF2A2 general transcription factor IIA, 2, 12kDa 1.39892
TRAK1 trafficking protein, kinesin binding 1 1.39685
SLCO4A1 solute carrier organic anion transporter family, member 4A1 1.39669
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 1.39563
USP38 ubiquitin specific peptidase 38 1.39545
ZNFX1 zinc finger, NFX1-type containing 1 1.3932
RAB9A RAB9A, member RAS oncogene family 1.38808
CTSA cathepsin A 1.38322
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 1.38292
BTBD11 BTB (POZ) domain containing 11 1.38264
GPR12 G protein-coupled receptor 12 1.38231
HIST1H2BD histone cluster 1, H2bd 1.3808
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa 1.38018
MPHOSPH8 M-phase phosphoprotein 8 1.37998
SLK STE20-like kinase 1.37699
CFHR5 complement factor H-related 5 1.37647
DAPK3 death-associated protein kinase 3 1.37562
RLIM ring finger protein, LIM domain interacting 1.37364
C12ORF40 chromosome 12 open reading frame 40 1.37364
EXOC1 exocyst complex component 1 1.37039
GUCA1A guanylate cyclase activator 1A (retina) 1.36954
ERICH1 glutamate-rich 1 1.36764
SLC37A3 solute carrier family 37, member 3 1.3669
ADGRD1 adhesion G protein-coupled receptor D1 1.36545
BANP BTG3 associated nuclear protein 1.3649
FMO2 flavin containing monooxygenase 2 (non-functional) 1.35856
FAM136A family with sequence similarity 136, member A 1.35738
MED26 mediator complex subunit 26 1.35676
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 1.35462
GPRC5C G protein-coupled receptor, class C, group 5, member C 1.35317
PRDM4 PR domain containing 4 1.35282
PGBD1 piggyBac transposable element derived 1 1.35005
LOC100128356 protein transactivated by hepatitis B virus E antigen 1.34922
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.34327
TADA2B transcriptional adaptor 2B 1.33966
TCTA T-cell leukemia translocation altered 1.33843
TMEM200A transmembrane protein 200A 1.33734
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.33579
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 1.32905
MKKS McKusick-Kaufman syndrome 1.32772
SUSD5 sushi domain containing 5 1.32743
MYL12B myosin, light chain 12B, regulatory 1.32425
ANXA4 annexin A4 1.32313
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.31628
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 1.31383
CHD8 chromodomain helicase DNA binding protein 8 1.31341
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.312
TRAPPC5 trafficking protein particle complex 5 1.31152
DDA1 DET1 and DDB1 associated 1 1.31122
C5ORF24 chromosome 5 open reading frame 24 1.3094
TRAF3IP3 TRAF3 interacting protein 3 1.30834
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.30663
FLT4 fms-related tyrosine kinase 4 1.30648
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.30533
GDF6 growth differentiation factor 6 1.30297
KRT18 keratin 18, type I 1.30188
SPATA2 spermatogenesis associated 2 1.30015
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 1.29948
NLRP2 NLR family, pyrin domain containing 2 1.29886
SHC4 SHC (Src homology 2 domain containing) family, member 4 1.29599
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 1.29316
FGFRL1 fibroblast growth factor receptor-like 1 1.29036
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 1.28852
IP6K1 inositol hexakisphosphate kinase 1 1.28675
DRG2 developmentally regulated GTP binding protein 2 1.28432
WIZ widely interspaced zinc finger motifs 1.28387
GPR39 G protein-coupled receptor 39 1.28386
PCDH9 protocadherin 9 1.28365
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C 1.28036
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.27903
SCARA3 scavenger receptor class A, member 3 1.27831
UBP1 upstream binding protein 1 (LBP-1a) 1.27108
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.26774
NDP Norrie disease (pseudoglioma) 1.26707
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.26692
LRPPRC leucine-rich pentatricopeptide repeat containing 1.26465
PSMC3IP PSMC3 interacting protein 1.26427

decreased expression

Symbol Name Standardized Value
MCOLN2 mucolipin 2 -4.30473
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 -4.22486
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -3.68082
ACER3 alkaline ceramidase 3 -3.61554
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -3.56329
STMN3 stathmin-like 3 -3.16603
WHSC1 Wolf-Hirschhorn syndrome candidate 1 -3.1576
PLSCR4 phospholipid scramblase 4 -3.05638
PIKFYVE phosphoinositide kinase, FYVE finger containing -3.0435
HRNR hornerin -2.91164
C11ORF58 chromosome 11 open reading frame 58 -2.87813
HINT1 histidine triad nucleotide binding protein 1 -2.86655
HEXB hexosaminidase B (beta polypeptide) -2.82708
UBA5 ubiquitin-like modifier activating enzyme 5 -2.81225
FBXL5 F-box and leucine-rich repeat protein 5 -2.79161
PACRGL PARK2 co-regulated-like -2.75755
EHD3 EH-domain containing 3 -2.74634
MMP2 matrix metallopeptidase 2 -2.73459
HDC histidine decarboxylase -2.73005
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -2.7081
TMSB4X thymosin beta 4, X-linked -2.70079
DRGX dorsal root ganglia homeobox -2.68473
MGP matrix Gla protein -2.6685
IGLV8-61 immunoglobulin lambda variable 8-61 -2.657
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -2.64498
PPP5C protein phosphatase 5, catalytic subunit -2.6349
MEF2C myocyte enhancer factor 2C -2.5875
GPBP1L1 GC-rich promoter binding protein 1-like 1 -2.58062
CSDE1 cold shock domain containing E1, RNA-binding -2.55058
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -2.54125
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -2.52279
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -2.465
TMEM47 transmembrane protein 47 -2.44673
ATP9A ATPase, class II, type 9A -2.41456
COMMD10 COMM domain containing 10 -2.37939
DPYD dihydropyrimidine dehydrogenase -2.37175
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -2.36924
PTGR2 prostaglandin reductase 2 -2.34678
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -2.32723
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -2.3151
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 -2.30061
AFAP1L2 actin filament associated protein 1-like 2 -2.29065
PTPRK protein tyrosine phosphatase, receptor type, K -2.29032
RPLP0 ribosomal protein, large, P0 -2.28819
SLITRK6 SLIT and NTRK-like family, member 6 -2.28747
PDCD2 programmed cell death 2 -2.28392
FCRL2 Fc receptor-like 2 -2.28209
ADD3 adducin 3 (gamma) -2.26201
TLK1 tousled-like kinase 1 -2.2394
ACAD9 acyl-CoA dehydrogenase family, member 9 -2.20973
TARSL2 threonyl-tRNA synthetase-like 2 -2.20872
RAB8B RAB8B, member RAS oncogene family -2.1976
RNF141 ring finger protein 141 -2.15945
NLRX1 NLR family member X1 -2.14934
MED21 mediator complex subunit 21 -2.13784
DENND5A DENN/MADD domain containing 5A -2.1365
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 -2.13218
UBAP1 ubiquitin associated protein 1 -2.12757
CLK4 CDC-like kinase 4 -2.11824
AEBP2 AE binding protein 2 -2.11497
DSCAML1 Down syndrome cell adhesion molecule like 1 -2.1057
TMEM120B transmembrane protein 120B -2.10098
GCDH glutaryl-CoA dehydrogenase -2.09654
R3HDM1 R3H domain containing 1 -2.07893
PGPEP1L pyroglutamyl-peptidase I-like -2.07676
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -2.06682
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 -2.06438
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase -2.0531
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -2.0434
RYBP RING1 and YY1 binding protein -2.04303
ZMYM4 zinc finger, MYM-type 4 -2.00189
CHRDL1 chordin-like 1 -1.97923
MED16 mediator complex subunit 16 -1.97364
CTSW cathepsin W -1.97101
RBPJ recombination signal binding protein for immunoglobulin kappa J region -1.96638
ITGB5 integrin, beta 5 -1.95617
CSNK1G3 casein kinase 1, gamma 3 -1.95256
BTF3 basic transcription factor 3 -1.94111
PURB purine-rich element binding protein B -1.93621
AMELY amelogenin, Y-linked -1.91697
FAM92A1 family with sequence similarity 92, member A1 -1.89987
ATXN10 ataxin 10 -1.89645
SH2D1A SH2 domain containing 1A -1.87988
ZNF177 zinc finger protein 177 -1.87745
MYO5A myosin VA (heavy chain 12, myoxin) -1.87599
BBS2 Bardet-Biedl syndrome 2 -1.87007
FBXO22 F-box protein 22 -1.86537
SRI sorcin -1.83555
OSBPL1A oxysterol binding protein-like 1A -1.8292
ADAMDEC1 ADAM-like, decysin 1 -1.82585
CKAP4 cytoskeleton-associated protein 4 -1.82013
CHPT1 choline phosphotransferase 1 -1.81573
FADS1 fatty acid desaturase 1 -1.81472
LRRC34 leucine rich repeat containing 34 -1.81301
NOL9 nucleolar protein 9 -1.80843
ZNF146 zinc finger protein 146 -1.80486
LMCD1 LIM and cysteine-rich domains 1 -1.80082
HAPLN1 hyaluronan and proteoglycan link protein 1 -1.79494
ATP11B ATPase, class VI, type 11B -1.78299
NUMB numb homolog (Drosophila) -1.78297
ZNF649 zinc finger protein 649 -1.78149
CREBZF CREB/ATF bZIP transcription factor -1.77817
RANBP9 RAN binding protein 9 -1.77613
SERGEF secretion regulating guanine nucleotide exchange factor -1.7708
MEX3A mex-3 RNA binding family member A -1.76588
POLR1B polymerase (RNA) I polypeptide B, 128kDa -1.76446
RPS13 ribosomal protein S13 -1.76263
RSBN1 round spermatid basic protein 1 -1.75123
H2BFWT H2B histone family, member W, testis-specific -1.731
RSAD2 radical S-adenosyl methionine domain containing 2 -1.72983
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -1.72938
CRTC3 CREB regulated transcription coactivator 3 -1.72345
ANXA11 annexin A11 -1.7189
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -1.71713
ZFAND5 zinc finger, AN1-type domain 5 -1.71087
APOB apolipoprotein B -1.70923
ZNF501 zinc finger protein 501 -1.70646
SRRM4 serine/arginine repetitive matrix 4 -1.69965
CLSTN2 calsyntenin 2 -1.69952
SHISA5 shisa family member 5 -1.69475
RFC1 replication factor C (activator 1) 1, 145kDa -1.69011
DZIP3 DAZ interacting zinc finger protein 3 -1.68762
STK3 serine/threonine kinase 3 -1.6819
CNRIP1 cannabinoid receptor interacting protein 1 -1.67892
EBPL emopamil binding protein-like -1.6767
CD302 CD302 molecule -1.6725
CHD3 chromodomain helicase DNA binding protein 3 -1.66783
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -1.65856
GABARAPL2 GABA(A) receptor-associated protein-like 2 -1.65547
PRELID2 PRELI domain containing 2 -1.64463
ZDHHC22 zinc finger, DHHC-type containing 22 -1.63297
SPTBN1 spectrin, beta, non-erythrocytic 1 -1.619
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -1.61792
C9ORF72 chromosome 9 open reading frame 72 -1.61712
KRTAP15-1 keratin associated protein 15-1 -1.61304
ETFA electron-transfer-flavoprotein, alpha polypeptide -1.60766
LAMP2 lysosomal-associated membrane protein 2 -1.60683
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -1.60476
KLHL8 kelch-like family member 8 -1.59926
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -1.59664
TRIT1 tRNA isopentenyltransferase 1 -1.58166
SH3PXD2A SH3 and PX domains 2A -1.5808
SOX10 SRY (sex determining region Y)-box 10 -1.57206
ITM2C integral membrane protein 2C -1.57174
ZBED5 zinc finger, BED-type containing 5 -1.56931
TMED5 transmembrane emp24 protein transport domain containing 5 -1.56865
KANK3 KN motif and ankyrin repeat domains 3 -1.56062
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha -1.55759
ST20 suppressor of tumorigenicity 20 -1.54053
TIMP3 TIMP metallopeptidase inhibitor 3 -1.53875
EHD4 EH-domain containing 4 -1.53668
ALPL alkaline phosphatase, liver/bone/kidney -1.53537
IGFBP7 insulin-like growth factor binding protein 7 -1.53445
LRP3 low density lipoprotein receptor-related protein 3 -1.53369
LIN9 lin-9 DREAM MuvB core complex component -1.52531
AZIN1 antizyme inhibitor 1 -1.52494
ZFP62 ZFP62 zinc finger protein -1.51458
STAG3L3 stromal antigen 3-like 3 (pseudogene) -1.51089
METRN meteorin, glial cell differentiation regulator -1.50936
WIPF1 WAS/WASL interacting protein family, member 1 -1.50405
ASCL2 achaete-scute family bHLH transcription factor 2 -1.49916
RPL39 ribosomal protein L39 -1.49771
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -1.49742
HAGHL hydroxyacylglutathione hydrolase-like -1.49236
LEF1 lymphoid enhancer-binding factor 1 -1.49077
IQCH IQ motif containing H -1.48407
PIGX phosphatidylinositol glycan anchor biosynthesis, class X -1.4838
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 -1.48375
MZT1 mitotic spindle organizing protein 1 -1.48207
PRKD1 protein kinase D1 -1.48172
OSMR oncostatin M receptor -1.47949
ZNF281 zinc finger protein 281 -1.4738
SETD6 SET domain containing 6 -1.46903
SNORA23 small nucleolar RNA, H/ACA box 23 -1.46475
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.46313
DGAT1 diacylglycerol O-acyltransferase 1 -1.46125
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -1.46085
ZNF626 zinc finger protein 626 -1.46055
HACD4 3-hydroxyacyl-CoA dehydratase 4 -1.45892
ESRP1 epithelial splicing regulatory protein 1 -1.45851
BGN biglycan -1.45821
PAN3 PAN3 poly(A) specific ribonuclease subunit -1.45199
SCRN2 secernin 2 -1.44911
OLFML2A olfactomedin-like 2A -1.44858
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -1.44834
HMBS hydroxymethylbilane synthase -1.44537
TRIM2 tripartite motif containing 2 -1.4417
RBM18 RNA binding motif protein 18 -1.44136
TSPAN13 tetraspanin 13 -1.43654
RAB31 RAB31, member RAS oncogene family -1.43575
OCRL oculocerebrorenal syndrome of Lowe -1.43523
CALCB calcitonin-related polypeptide beta -1.43038
PRIM1 primase, DNA, polypeptide 1 (49kDa) -1.42982
ANXA7 annexin A7 -1.42868
SUB1 SUB1 homolog (S. cerevisiae) -1.42549
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 -1.42386
MAP6 microtubule-associated protein 6 -1.42337
TTTY5 testis-specific transcript, Y-linked 5 (non-protein coding) -1.41588
STXBP2 syntaxin binding protein 2 -1.41163
RPTOR regulatory associated protein of MTOR, complex 1 -1.40989
ZC3H14 zinc finger CCCH-type containing 14 -1.4093
POU6F1 POU class 6 homeobox 1 -1.40764
YES1 YES proto-oncogene 1, Src family tyrosine kinase -1.40233
LSM12 LSM12 homolog (S. cerevisiae) -1.3999
TSGA10 testis specific, 10 -1.39876
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) -1.39826
GPSM1 G-protein signaling modulator 1 -1.39755
C2ORF70 chromosome 2 open reading frame 70 -1.38812
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -1.38717
COL14A1 collagen, type XIV, alpha 1 -1.38683
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -1.38583
SERTAD4 SERTA domain containing 4 -1.38051
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -1.37491
ZNF451 zinc finger protein 451 -1.37155
BAMBI BMP and activin membrane-bound inhibitor -1.37097
LOC100130927 uncharacterized LOC100130927 -1.36505
GRAMD4 GRAM domain containing 4 -1.36157
TROVE2 TROVE domain family, member 2 -1.36101
REL v-rel avian reticuloendotheliosis viral oncogene homolog -1.36081
FAM169A family with sequence similarity 169, member A -1.35906
STRA6 stimulated by retinoic acid 6 -1.35523
CREBL2 cAMP responsive element binding protein-like 2 -1.34958
GRIA1 glutamate receptor, ionotropic, AMPA 1 -1.34846
ACTN1 actinin, alpha 1 -1.3482
MRC2 mannose receptor, C type 2 -1.34449
RBMS1 RNA binding motif, single stranded interacting protein 1 -1.34273
IRX2 iroquois homeobox 2 -1.34176
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -1.34014
SCLT1 sodium channel and clathrin linker 1 -1.33906
DOK4 docking protein 4 -1.33902
APLP1 amyloid beta (A4) precursor-like protein 1 -1.33886
PTPRF protein tyrosine phosphatase, receptor type, F -1.33386
SPACA1 sperm acrosome associated 1 -1.33213
MRPL42 mitochondrial ribosomal protein L42 -1.3318
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -1.32885
PRCP prolylcarboxypeptidase (angiotensinase C) -1.32873
MAML2 mastermind-like 2 (Drosophila) -1.3265
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -1.32421
LPCAT2 lysophosphatidylcholine acyltransferase 2 -1.32248
COCH cochlin -1.3182
RPL9 ribosomal protein L9 -1.31367
FGFR2 fibroblast growth factor receptor 2 -1.3135
DOCK7 dedicator of cytokinesis 7 -1.31159
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -1.31145
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -1.31085
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -1.31034
TRPV4 transient receptor potential cation channel, subfamily V, member 4 -1.30837
CCDC85B coiled-coil domain containing 85B -1.30779
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -1.30599
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.30542
AASDH aminoadipate-semialdehyde dehydrogenase -1.30431
ZNF772 zinc finger protein 772 -1.30288
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III -1.30265
EIF2A eukaryotic translation initiation factor 2A, 65kDa -1.30224
SMC6 structural maintenance of chromosomes 6 -1.29561
MIPOL1 mirror-image polydactyly 1 -1.29418
RXRB retinoid X receptor, beta -1.29406
FBXO7 F-box protein 7 -1.29403
KLHL5 kelch-like family member 5 -1.2906
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -1.29047
IPO5 importin 5 -1.28859
SGMS2 sphingomyelin synthase 2 -1.28849
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase -1.27913
AKR1C1 aldo-keto reductase family 1, member C1 -1.2761
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -1.27497
NDFIP1 Nedd4 family interacting protein 1 -1.27333
PDLIM2 PDZ and LIM domain 2 (mystique) -1.27289
SVIL supervillin -1.26901
PARP15 poly (ADP-ribose) polymerase family, member 15 -1.26775
MPHOSPH9 M-phase phosphoprotein 9 -1.26757
OSBPL10 oxysterol binding protein-like 10 -1.26603
D2HGDH D-2-hydroxyglutarate dehydrogenase -1.26525
AK5 adenylate kinase 5 -1.26495
FAM114A2 family with sequence similarity 114, member A2 -1.2646
CCDC71 coiled-coil domain containing 71 -1.26411
TECRL trans-2,3-enoyl-CoA reductase-like -1.2621
IFT80 intraflagellar transport 80 -1.26206
EFR3A EFR3 homolog A (S. cerevisiae) -1.25833
KIAA0895 KIAA0895 -1.25824
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) -1.25484
LELP1 late cornified envelope-like proline-rich 1 -1.2546
C5ORF51 chromosome 5 open reading frame 51 -1.25319
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -1.24681
PDLIM3 PDZ and LIM domain 3 -1.24658
DACH1 dachshund family transcription factor 1 -1.24635
DUOX2 dual oxidase 2 -1.24588
ERBB3 erb-b2 receptor tyrosine kinase 3 -1.24557
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -1.24475
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 -1.2434
TMEM14C transmembrane protein 14C -1.24333
OSBP oxysterol binding protein -1.24241
ZCCHC9 zinc finger, CCHC domain containing 9 -1.23923
DAB2IP DAB2 interacting protein -1.23262
CCNL2 cyclin L2 -1.23041
RPL21 ribosomal protein L21 -1.2261
LOC100129831 -1.22447
DCAF4 DDB1 and CUL4 associated factor 4 -1.22276
WDR36 WD repeat domain 36 -1.22102
HOXC4 homeobox C4 -1.21942
ANTXR1 anthrax toxin receptor 1 -1.21853
Funding