MAPK11 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description mitogen-activated protein kinase 11|This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 5600)
External Link https://ncbi.nlm.nih.gov/gene/5600
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Genes

498 genes differentially expressed following the MAPK11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FABP4 fatty acid binding protein 4, adipocyte 0.0168838
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0158505
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0124417
CAV1 caveolin 1, caveolae protein, 22kDa 0.0120276
SNAP25 synaptosomal-associated protein, 25kDa 0.0118039
IFI16 interferon, gamma-inducible protein 16 0.011181
STOM stomatin 0.0109033
CAV2 caveolin 2 0.0106536
PSAT1 phosphoserine aminotransferase 1 0.0103943
AKAP12 A kinase (PRKA) anchor protein 12 0.0103162
DEFB1 defensin, beta 1 0.0102302
NRN1 neuritin 1 0.0101074
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0100244
COL15A1 collagen, type XV, alpha 1 0.00998444
XPO7 exportin 7 0.00998217
MYBPC1 myosin binding protein C, slow type 0.00966757
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00963835
NIBAN1 niban apoptosis regulator 1 0.0095233
CHN1 chimerin 1 0.0093777
SYT1 synaptotagmin I 0.00935422
LAMP3 lysosomal-associated membrane protein 3 0.00933386
AQP1 aquaporin 1 (Colton blood group) 0.00928895
KRT17 keratin 17, type I 0.00927187
KRT13 keratin 13, type I 0.00923081
PDE4B phosphodiesterase 4B, cAMP-specific 0.0091648
RGCC regulator of cell cycle 0.00905829
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00901866
GRB7 growth factor receptor-bound protein 7 0.00894665
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00890316
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00889243
GIMAP4 GTPase, IMAP family member 4 0.0088855
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00888541
PLTP phospholipid transfer protein 0.00867182
SPRR3 small proline-rich protein 3 0.00862005
S100A9 S100 calcium binding protein A9 0.00861743
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00860487
SRSF1 serine/arginine-rich splicing factor 1 0.00856279
MECOM MDS1 and EVI1 complex locus 0.00855232
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00855071
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00852929
MSX1 msh homeobox 1 0.00849633
F13A1 coagulation factor XIII, A1 polypeptide 0.00847082
SPARCL1 SPARC-like 1 (hevin) 0.00837629
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00832805
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0082416
FHL1 four and a half LIM domains 1 0.00823727
OXTR oxytocin receptor 0.00812342
VWF von Willebrand factor 0.00812161
CSRP2 cysteine and glycine-rich protein 2 0.00809114
SLPI secretory leukocyte peptidase inhibitor 0.00781414
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00777946
LMO2 LIM domain only 2 (rhombotin-like 1) 0.0077757
CHRDL1 chordin-like 1 0.00775894
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00775857
PEA15 phosphoprotein enriched in astrocytes 15 0.00768079
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00767474
GPM6B glycoprotein M6B 0.00767428
COG5 component of oligomeric golgi complex 5 0.00767034
SLC35G2 solute carrier family 35, member G2 0.00765142
DAZAP2 DAZ associated protein 2 0.00763675
S100A2 S100 calcium binding protein A2 0.0076295
PDAP1 PDGFA associated protein 1 0.00760771
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00758226
WFDC2 WAP four-disulfide core domain 2 0.00754355
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00750344
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00746699
LUM lumican 0.00743388
FXYD3 FXYD domain containing ion transport regulator 3 0.00740576
PTGES prostaglandin E synthase 0.00739769
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00737683
MAGEA3 melanoma antigen family A3 0.00731512
NTS neurotensin 0.00729451
EGFL6 EGF-like-domain, multiple 6 0.00728373
ATAD2 ATPase family, AAA domain containing 2 0.00723926
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 0.00723372
C3 complement component 3 0.00723108
IFI44L interferon-induced protein 44-like 0.0071996
PRNP prion protein 0.00719346
STATH statherin 0.00719249
SET SET nuclear proto-oncogene 0.00717585
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00716285
EGR2 early growth response 2 0.00716162
MYO1C myosin IC 0.00713071
SOX11 SRY (sex determining region Y)-box 11 0.00712593
CLDND1 claudin domain containing 1 0.00696759
SELL selectin L 0.00696391
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00689173
GDE1 glycerophosphodiester phosphodiesterase 1 0.00687251
CFD complement factor D (adipsin) 0.00684432
CCL4 chemokine (C-C motif) ligand 4 0.00683746
GIMAP6 GTPase, IMAP family member 6 0.00683129
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00682529
RDX radixin 0.00682011
C10ORF10 chromosome 10 open reading frame 10 0.00680863
HILPDA hypoxia inducible lipid droplet-associated 0.00679622
TRIM38 tripartite motif containing 38 0.00678441
IFI27 interferon, alpha-inducible protein 27 0.00678349
IL1RN interleukin 1 receptor antagonist 0.00677855
KIF14 kinesin family member 14 0.00677473
MME membrane metallo-endopeptidase 0.00675935
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00675327
CD93 CD93 molecule 0.00669096
PRMT1 protein arginine methyltransferase 1 0.0066695
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00665765
GANAB glucosidase, alpha; neutral AB 0.00663304
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 0.00661511
TGM2 transglutaminase 2 0.00658923
DCTN4 dynactin 4 (p62) 0.00657517
TCF12 transcription factor 12 0.006558
PRAME preferentially expressed antigen in melanoma 0.00653526
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00649916
APOL1 apolipoprotein L, 1 0.00648011
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00646171
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00644947
ACTB actin, beta 0.00644365
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00636232
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00633227
IARS1 isoleucyl-tRNA synthetase 1 0.00631642
CFH complement factor H 0.00631601
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.00629221
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00628034
TUBB2A tubulin, beta 2A class IIa 0.00624501
HOXB7 homeobox B7 0.00624097
MMP10 matrix metallopeptidase 10 0.00623981
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00623764
GNAS GNAS complex locus 0.00623156
PPARG peroxisome proliferator-activated receptor gamma 0.00622564
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00622016
SFRP1 secreted frizzled-related protein 1 0.00621144
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.00620862
CANX calnexin 0.00620197
UBE2H ubiquitin-conjugating enzyme E2H 0.00617972
SMC1A structural maintenance of chromosomes 1A 0.00616227
CES1 carboxylesterase 1 0.00615781
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00614245
TAL1 T-cell acute lymphocytic leukemia 1 0.00614069
GYPC glycophorin C (Gerbich blood group) 0.00613761
CSTA cystatin A (stefin A) 0.00613687
BIRC3 baculoviral IAP repeat containing 3 0.00612118
ERGIC2 ERGIC and golgi 2 0.00611639
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00611636
PLP1 proteolipid protein 1 0.00610183
CHEK1 checkpoint kinase 1 0.00608563
SORBS1 sorbin and SH3 domain containing 1 0.00608419
KIF18A kinesin family member 18A 0.00607279
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.0060478
IL15 interleukin 15 0.00601531
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00599978
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0059945
COPA coatomer protein complex, subunit alpha 0.00598221
LY6D lymphocyte antigen 6 complex, locus D 0.00598165
MED6 mediator complex subunit 6 0.00597853
KRT5 keratin 5, type II 0.0059445
RBBP4 retinoblastoma binding protein 4 0.00593368
MTUS1 microtubule associated tumor suppressor 1 0.00592923
MYH10 myosin, heavy chain 10, non-muscle 0.00591985
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00590641
RHOA ras homolog family member A 0.00590607
MFAP4 microfibrillar-associated protein 4 0.00589552
LDB3 LIM domain binding 3 0.00585464
UPK1B uroplakin 1B 0.00585418
IER2 immediate early response 2 0.00584571
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00584085
BCL6 B-cell CLL/lymphoma 6 0.00583384
PBK PDZ binding kinase 0.00583067
LHFP lipoma HMGIC fusion partner 0.00582892
BCHE butyrylcholinesterase 0.00581018
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00580625
ANXA1 annexin A1 0.00579927
AQP9 aquaporin 9 0.00578938
LAMA4 laminin, alpha 4 0.00578588
RSL1D1 ribosomal L1 domain containing 1 0.00578383
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0057783
MSR1 macrophage scavenger receptor 1 0.00575436
A2M alpha-2-macroglobulin 0.00574085
HLA-B major histocompatibility complex, class I, B 0.00573663
BAG2 BCL2-associated athanogene 2 0.00571388
CTTN cortactin 0.00570843
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00570768
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00569947
ABLIM1 actin binding LIM protein 1 0.00566756
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00566485
PDZD2 PDZ domain containing 2 0.00565838
ADCY3 adenylate cyclase 3 0.00565308
LOX lysyl oxidase 0.00565075
GOLM1 golgi membrane protein 1 0.00563994
CPOX coproporphyrinogen oxidase 0.00563359
NCF2 neutrophil cytosolic factor 2 0.00562949
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.0056212
ANO1 anoctamin 1, calcium activated chloride channel 0.00561116
TMEM100 transmembrane protein 100 0.00555488
CDC6 cell division cycle 6 0.0055454
MARF1 meiosis regulator and mRNA stability factor 1 0.00553937
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.0055357
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00553321
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00552416
PRKCH protein kinase C, eta 0.00552365
RLN1 relaxin 1 0.00551084
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00548841
AADAC arylacetamide deacetylase 0.00548326
CCNG1 cyclin G1 0.00546818
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.00546605
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.00546108
IFNG interferon, gamma 0.00545858
MIA melanoma inhibitory activity 0.00545736
TPM2 tropomyosin 2 (beta) 0.00543739
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.00543135
CD99 CD99 molecule 0.00542662
PRDX2 peroxiredoxin 2 0.00539983
C8ORF4 chromosome 8 open reading frame 4 0.00538577
S100A7 S100 calcium binding protein A7 0.00538105
ATG5 autophagy related 5 0.00536949
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00536404
SORD sorbitol dehydrogenase 0.00535782
C1ORF112 chromosome 1 open reading frame 112 0.00534194
MNDA myeloid cell nuclear differentiation antigen 0.00533523
FKBP11 FK506 binding protein 11, 19 kDa 0.00532746
RPS26 ribosomal protein S26 0.00532579
RSAD2 radical S-adenosyl methionine domain containing 2 0.00531939
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00531849
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.00528615
ETNPPL ethanolamine-phosphate phospho-lyase 0.00528558
MT1E metallothionein 1E 0.00528194
IFI44 interferon-induced protein 44 0.00528054
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00527381
LGALS13 lectin, galactoside-binding, soluble, 13 0.00525751
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00523554
CCNA2 cyclin A2 0.0052305
MKI67 marker of proliferation Ki-67 0.00522884
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00522673
CAPRIN1 cell cycle associated protein 1 0.00522597
NKX2-1 NK2 homeobox 1 0.00522384
OLFM1 olfactomedin 1 0.00521771
SMC2 structural maintenance of chromosomes 2 0.0052131
IRS2 insulin receptor substrate 2 0.00519863
AUH AU RNA binding protein/enoyl-CoA hydratase 0.00519783
UBXN7 UBX domain protein 7 0.00519608
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.00519466
PBX1 pre-B-cell leukemia homeobox 1 0.00518362
CNTN1 contactin 1 0.00517086
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00516083
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.0051484
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.00514234
NELL2 NEL-like 2 (chicken) 0.00514226
TP63 tumor protein p63 0.00513507
CHTOP chromatin target of PRMT1 0.00512979
C1S complement component 1, s subcomponent 0.00512395
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00512288
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.00512275

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0209049
HTRA1 HtrA serine peptidase 1 -0.013734
IPO13 importin 13 -0.0129361
CXCL14 chemokine (C-X-C motif) ligand 14 -0.011951
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0107035
CTSD cathepsin D -0.0103929
P3H2 prolyl 3-hydroxylase 2 -0.00992574
TTC39A tetratricopeptide repeat domain 39A -0.00980678
PTK2B protein tyrosine kinase 2 beta -0.00980093
GATA6 GATA binding protein 6 -0.00967803
LCN2 lipocalin 2 -0.009614
PCP4 Purkinje cell protein 4 -0.00959955
H1-2 H1.2 linker histone, cluster member -0.00947922
SLC38A1 solute carrier family 38, member 1 -0.00935361
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00934868
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00916835
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00909761
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00907181
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00900009
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0089719
PHACTR2 phosphatase and actin regulator 2 -0.00895057
AGR2 anterior gradient 2 -0.00891305
DLK1 delta-like 1 homolog (Drosophila) -0.00867744
SATB2 SATB homeobox 2 -0.00864553
NDRG1 N-myc downstream regulated 1 -0.0085567
QPCT glutaminyl-peptide cyclotransferase -0.00853467
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00848484
DPP4 dipeptidyl-peptidase 4 -0.00846454
HIST1H2BK histone cluster 1, H2bk -0.0084005
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00838089
VCAM1 vascular cell adhesion molecule 1 -0.00828671
TPSAB1 tryptase alpha/beta 1 -0.00828579
CLCA1 chloride channel accessory 1 -0.00820518
MMP9 matrix metallopeptidase 9 -0.0081987
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00819143
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00809386
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00778099
FST follistatin -0.00776851
CA12 carbonic anhydrase XII -0.00775952
AOC1 amine oxidase, copper containing 1 -0.0077531
FCGBP Fc fragment of IgG binding protein -0.00773805
CLDN3 claudin 3 -0.00771668
PEG10 paternally expressed 10 -0.00771021
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00768126
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00762114
PERP PERP, TP53 apoptosis effector -0.00760106
GLS glutaminase -0.00759721
AMDHD2 amidohydrolase domain containing 2 -0.00758526
OLFM4 olfactomedin 4 -0.00755703
STK26 serine/threonine protein kinase 26 -0.00754132
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00754087
ZG16 zymogen granule protein 16 -0.0074823
PLAAT3 phospholipase A and acyltransferase 3 -0.00740079
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00739109
HEPH hephaestin -0.00734689
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00734476
TM4SF1 transmembrane 4 L six family member 1 -0.00733727
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00733645
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00732381
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00729857
S100A10 S100 calcium binding protein A10 -0.0071898
COMP cartilage oligomeric matrix protein -0.00712614
CTSA cathepsin A -0.00707605
TES testin LIM domain protein -0.00706542
DSP desmoplakin -0.00704512
MPC2 mitochondrial pyruvate carrier 2 -0.00703465
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00703149
REG1A regenerating islet-derived 1 alpha -0.00701967
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00697758
MARCKSL1 MARCKS-like 1 -0.00695128
SKAP2 src kinase associated phosphoprotein 2 -0.00693119
SPATA20 spermatogenesis associated 20 -0.00692696
CD177 CD177 molecule -0.00685941
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -0.00685848
NPTX2 neuronal pentraxin II -0.00684443
TOX3 TOX high mobility group box family member 3 -0.00684313
BGN biglycan -0.00678028
ACAA2 acetyl-CoA acyltransferase 2 -0.00676733
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00670959
ISYNA1 inositol-3-phosphate synthase 1 -0.00670532
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00668414
NINJ2 ninjurin 2 -0.00667895
RNF19B ring finger protein 19B -0.00663379
XYLT1 xylosyltransferase I -0.00660302
TARP TCR gamma alternate reading frame protein -0.00660059
TGFBI transforming growth factor, beta-induced, 68kDa -0.00656902
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00652527
SLC46A3 solute carrier family 46, member 3 -0.00652017
DYNLL1 dynein, light chain, LC8-type 1 -0.00646979
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00644419
PEG3 paternally expressed 3 -0.00644383
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00643712
NPC2 Niemann-Pick disease, type C2 -0.0064267
EFNB2 ephrin-B2 -0.00641333
ANKRD10 ankyrin repeat domain 10 -0.00641293
FTH1 ferritin, heavy polypeptide 1 -0.0063991
TSPAN4 tetraspanin 4 -0.00636509
GAS6 growth arrest-specific 6 -0.0063523
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00634346
FAM162A family with sequence similarity 162, member A -0.00631491
HPCAL1 hippocalcin-like 1 -0.00626582
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00623707
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00616058
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00612654
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00611935
QPRT quinolinate phosphoribosyltransferase -0.00611926
SFRP4 secreted frizzled-related protein 4 -0.00611106
THBS1 thrombospondin 1 -0.00610867
DAAM1 dishevelled associated activator of morphogenesis 1 -0.00609457
ATG2A autophagy related 2A -0.00605262
LMNA lamin A/C -0.00605261
GALC galactosylceramidase -0.00604719
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.00602719
SHB Src homology 2 domain containing adaptor protein B -0.0060118
PFKL phosphofructokinase, liver -0.00599487
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00598821
PHF1 PHD finger protein 1 -0.00598335
CRLF1 cytokine receptor-like factor 1 -0.0059712
ABHD2 abhydrolase domain containing 2 -0.00596278
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00596141
VAV3 vav 3 guanine nucleotide exchange factor -0.00595136
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00593417
DACH1 dachshund family transcription factor 1 -0.00590691
PRSS3 protease, serine, 3 -0.00588658
HIST1H2BD histone cluster 1, H2bd -0.00587803
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.0058756
MYO6 myosin VI -0.00587051
OSBPL10 oxysterol binding protein-like 10 -0.0058675
CLC Charcot-Leyden crystal galectin -0.00586142
TFF1 trefoil factor 1 -0.00585449
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00579865
ELN elastin -0.00579663
LXN latexin -0.00579611
MINK1 misshapen-like kinase 1 -0.00576368
NOX1 NADPH oxidase 1 -0.00575345
HIST1H2AC histone cluster 1, H2ac -0.00574935
REG1B regenerating islet-derived 1 beta -0.00571598
TSPAN12 tetraspanin 12 -0.00571552
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00569839
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00568599
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00566496
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00565522
TMEM176A transmembrane protein 176A -0.00565359
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00565003
INAVA innate immunity activator -0.00563502
CLTB clathrin, light chain B -0.00563038
GUCA2A guanylate cyclase activator 2A (guanylin) -0.00562668
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00561942
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.005617
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00560822
GOLGA8H golgin A8 family, member H -0.00560603
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00560279
PRKCI protein kinase C, iota -0.0055959
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -0.00556496
COG2 component of oligomeric golgi complex 2 -0.0055351
SC5D sterol-C5-desaturase -0.0055281
DNASE1L3 deoxyribonuclease I-like 3 -0.00552494
GGTLC1 gamma-glutamyltransferase light chain 1 -0.00551859
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -0.00548644
CPTP ceramide-1-phosphate transfer protein -0.00548104
CHKB choline kinase beta -0.00547882
NOTCH1 notch 1 -0.00546947
ARL4C ADP-ribosylation factor-like 4C -0.0054632
COL2A1 collagen, type II, alpha 1 -0.00543059
KLK1 kallikrein 1 -0.00542001
CAMP cathelicidin antimicrobial peptide -0.00541607
KCNK5 potassium channel, two pore domain subfamily K, member 5 -0.00541145
GCG glucagon -0.0053962
PKP2 plakophilin 2 -0.00539431
CTSH cathepsin H -0.00538597
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.00538376
INHBA inhibin, beta A -0.00537694
SH3YL1 SH3 and SYLF domain containing 1 -0.00537516
TRAPPC6A trafficking protein particle complex 6A -0.00536363
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0053484
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00534368
LYZ lysozyme -0.00534127
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00532905
CCN2 cellular communication network factor 2 -0.00532839
PPT1 palmitoyl-protein thioesterase 1 -0.0053221
EML3 echinoderm microtubule associated protein like 3 -0.00531774
ZNF83 zinc finger protein 83 -0.00531598
SGSM2 small G protein signaling modulator 2 -0.0053111
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00530259
H2AX H2A.X variant histone -0.00529191
NID2 nidogen 2 (osteonidogen) -0.00528741
TMEM14A transmembrane protein 14A -0.00528247
PLXND1 plexin D1 -0.00527426
CALML3 calmodulin-like 3 -0.00524008
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.00521756
EXPH5 exophilin 5 -0.00521454
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00520583
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0052048
PROM1 prominin 1 -0.00519478
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00519325
GOLIM4 golgi integral membrane protein 4 -0.00518437
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.00517913
DPYSL2 dihydropyrimidinase-like 2 -0.00517578
C2 complement component 2 -0.00517452
TRIB2 tribbles pseudokinase 2 -0.00517071
MICALL2 MICAL-like 2 -0.00515745
SNX7 sorting nexin 7 -0.00515202
ADSL adenylosuccinate lyase -0.00515155
GSTM3 glutathione S-transferase mu 3 (brain) -0.00515127
AEBP1 AE binding protein 1 -0.00514667
NOTCH2NL notch 2 N-terminal like -0.00513819
ARHGAP22 Rho GTPase activating protein 22 -0.00513608
CTNND1 catenin (cadherin-associated protein), delta 1 -0.00512639
AFP alpha-fetoprotein -0.00512567
UGDH UDP-glucose 6-dehydrogenase -0.00511975
TULP4 tubby like protein 4 -0.00511634
OPN3 opsin 3 -0.00510673
TARDBP TAR DNA binding protein -0.00510343
KIF1A kinesin family member 1A -0.00509774
DEPTOR DEP domain containing MTOR-interacting protein -0.00508976
ZNF91 zinc finger protein 91 -0.00508509
SPRY4 sprouty homolog 4 (Drosophila) -0.00504998
RRAGC Ras-related GTP binding C -0.00504557
PRUNE2 prune homolog 2 (Drosophila) -0.00503599
COL16A1 collagen, type XVI, alpha 1 -0.00501862
GSE1 Gse1 coiled-coil protein -0.00501348
SPRY2 sprouty homolog 2 (Drosophila) -0.00501214
EFHD2 EF-hand domain family, member D2 -0.00500858
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00499881
PLXNC1 plexin C1 -0.0049884
EXOC3 exocyst complex component 3 -0.00497843
GSTT1 glutathione S-transferase theta 1 -0.00497288
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00496882
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00493995
FHOD1 formin homology 2 domain containing 1 -0.00493618
RGS16 regulator of G-protein signaling 16 -0.00493484
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00493483
ANKRD11 ankyrin repeat domain 11 -0.00492232
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -0.00490832
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00490281
KDM6B lysine (K)-specific demethylase 6B -0.00489623
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00488782
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00488586
RAB32 RAB32, member RAS oncogene family -0.00488044
BAMBI BMP and activin membrane-bound inhibitor -0.00487955
AHR aryl hydrocarbon receptor -0.00486957
ICA1 islet cell autoantigen 1, 69kDa -0.00486639
KRT8 keratin 8, type II -0.00485963
GRAMD4 GRAM domain containing 4 -0.00484556
LSR lipolysis stimulated lipoprotein receptor -0.00483126
GGT1 gamma-glutamyltransferase 1 -0.00483084
GRSF1 G-rich RNA sequence binding factor 1 -0.00482945
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00482557
SIDT1 SID1 transmembrane family, member 1 -0.00482106