MAPK11 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description mitogen-activated protein kinase 11|This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 5600)
External Link http://www.ncbi.nlm.nih.gov/gene/5600
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181 interacting proteins for MAPK11 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
ARHGAP12 Rho GTPase activating protein 12
ARRB2 arrestin, beta 2
ATF2 activating transcription factor 2
ATF6 activating transcription factor 6
BAG3 BCL2-associated athanogene 3
BCL2 B-cell CLL/lymphoma 2
BLK BLK proto-oncogene, Src family tyrosine kinase
BMI1 BMI1 proto-oncogene, polycomb ring finger
C9ORF78 chromosome 9 open reading frame 78
CBX2 chromobox homolog 2
CBX4 chromobox homolog 4
CBX6 chromobox homolog 6
CBX8 chromobox homolog 8
CCDC8 coiled-coil domain containing 8
CCM2 cerebral cavernous malformation 2
CCND1 cyclin D1
CCND3 cyclin D3
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDC25B cell division cycle 25B
CDC42 cell division cycle 42
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CPNE6 copine VI (neuronal)
CREB1 cAMP responsive element binding protein 1
CUL7 cullin 7
DDIT3 DNA-damage-inducible transcript 3
DSCAM Down syndrome cell adhesion molecule
DUSP10 dual specificity phosphatase 10
DUSP16 dual specificity phosphatase 16
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
E2F1 E2F transcription factor 1
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ELK1 ELK1, member of ETS oncogene family
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV1 ets variant 1
EWSR1 EWS RNA-binding protein 1
FGR FGR proto-oncogene, Src family tyrosine kinase
FOS FBJ murine osteosarcoma viral oncogene homolog
FYN FYN proto-oncogene, Src family tyrosine kinase
GDI1 GDP dissociation inhibitor 1
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GYS1 glycogen synthase 1 (muscle)
H2AFB1 H2A histone family, member B1
H2AFX H2A histone family, member X
H2AFZ H2A histone family, member Z
H2BFS H2B histone family, member S (pseudogene)
H3F3A H3 histone, family 3A
HCK HCK proto-oncogene, Src family tyrosine kinase
HDAC3 histone deacetylase 3
HIST1H2AB histone cluster 1, H2ab
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BA histone cluster 1, H2ba
HIST1H2BB histone cluster 1, H2bb
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BK histone cluster 1, H2bk
HIST1H2BL histone cluster 1, H2bl
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HIST2H2AC histone cluster 2, H2ac
HIST2H2BE histone cluster 2, H2be
HIST2H3A histone cluster 2, H3a
HIST3H2BB histone cluster 3, H2bb
HNF4A hepatocyte nuclear factor 4, alpha
HSPB1 heat shock 27kDa protein 1
HTRA2 HtrA serine peptidase 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUN jun proto-oncogene
KDR kinase insert domain receptor
KHSRP KH-type splicing regulatory protein
KRT1 keratin 1, type II
KRT19 keratin 19, type I
KRT8 keratin 8, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LSP1 lymphocyte-specific protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K7CL MAP3K7 C-terminal like
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAPT microtubule-associated protein tau
MAX MYC associated factor X
MBP myelin basic protein
MEF2A myocyte enhancer factor 2A
MEF2B myocyte enhancer factor 2B
MEF2C myocyte enhancer factor 2C
MEF2D myocyte enhancer factor 2D
MITF microphthalmia-associated transcription factor
MKNK1 MAP kinase interacting serine/threonine kinase 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOXA1 NADPH oxidase activator 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OBSL1 obscurin-like 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PHC2 polyhomeotic homolog 2 (Drosophila)
PHC3 polyhomeotic homolog 3 (Drosophila)
PKN1 protein kinase N1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PML promyelocytic leukemia
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKCE protein kinase C, epsilon
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RING1 ring finger protein 1
RNF2 ring finger protein 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPTOR regulatory associated protein of MTOR, complex 1
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SH2D1A SH2 domain containing 1A
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOCS3 suppressor of cytokine signaling 3
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYK spleen tyrosine kinase
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TCF3 transcription factor 3
TH tyrosine hydroxylase
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSC2 tuberous sclerosis 2
USF1 upstream transcription factor 1
VARS valyl-tRNA synthetase
VEGFA vascular endothelial growth factor A
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNHIT1 zinc finger, HIT-type containing 1