| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | mitogen-activated protein kinase 14|The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1432) |
| External Link | https://ncbi.nlm.nih.gov/gene/1432 |
| Similar Terms | |
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499 genes differentially expressed following the MAPK14 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.0127036 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.012645 |
| HTRA1 | HtrA serine peptidase 1 | 0.0106015 |
| NID2 | nidogen 2 (osteonidogen) | 0.0104306 |
| ZNF395 | zinc finger protein 395 | 0.0103335 |
| SYNGR3 | synaptogyrin 3 | 0.0103041 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00998433 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00937863 |
| TNC | tenascin C | 0.00899068 |
| RGS1 | regulator of G-protein signaling 1 | 0.00898909 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.00877615 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00873188 |
| AGRN | agrin | 0.00873092 |
| CA12 | carbonic anhydrase XII | 0.00831896 |
| RNF167 | ring finger protein 167 | 0.00814188 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00805846 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00795726 |
| GNAS | GNAS complex locus | 0.00785669 |
| STMN2 | stathmin 2 | 0.00779089 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00769534 |
| MMD | monocyte to macrophage differentiation-associated | 0.00754074 |
| L1CAM | L1 cell adhesion molecule | 0.0074796 |
| NVL | nuclear VCP-like | 0.00744209 |
| CD200 | CD200 molecule | 0.00739487 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.0073866 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.0073625 |
| FAM13A | family with sequence similarity 13, member A | 0.00709325 |
| MEIS2 | Meis homeobox 2 | 0.00709023 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00698804 |
| NAV2 | neuron navigator 2 | 0.00680993 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.00680718 |
| PLXNA1 | plexin A1 | 0.00680646 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00668863 |
| ITGAV | integrin, alpha V | 0.00666781 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00645176 |
| RGS5 | regulator of G-protein signaling 5 | 0.00642803 |
| TLN1 | talin 1 | 0.00641046 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00640527 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00640358 |
| DEFB1 | defensin, beta 1 | 0.00640147 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00637166 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.0063001 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00623689 |
| BEX4 | brain expressed, X-linked 4 | 0.0061973 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00613942 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00610181 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00609285 |
| PKM | pyruvate kinase, muscle | 0.00609235 |
| PLAT | plasminogen activator, tissue | 0.00604226 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00602965 |
| FBN2 | fibrillin 2 | 0.00598742 |
| PLXNC1 | plexin C1 | 0.00591877 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00591048 |
| CLCA1 | chloride channel accessory 1 | 0.00590253 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00586509 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00585446 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00582775 |
| FCGBP | Fc fragment of IgG binding protein | 0.00581994 |
| AUTS2 | autism susceptibility candidate 2 | 0.00580959 |
| REG3A | regenerating islet-derived 3 alpha | 0.00571398 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0057114 |
| RORA | RAR-related orphan receptor A | 0.00570427 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00568836 |
| MMP9 | matrix metallopeptidase 9 | 0.00568061 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00565824 |
| NPY | neuropeptide Y | 0.00561826 |
| SFRP1 | secreted frizzled-related protein 1 | 0.005613 |
| MYO1D | myosin ID | 0.00560628 |
| GDF15 | growth differentiation factor 15 | 0.00559923 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00559118 |
| RTN1 | reticulon 1 | 0.00558223 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00557276 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00557142 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00556696 |
| HLTF | helicase-like transcription factor | 0.00551891 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00546967 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00545974 |
| ZG16 | zymogen granule protein 16 | 0.00539607 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00538192 |
| SHTN1 | shootin 1 | 0.00536529 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00533356 |
| S100A10 | S100 calcium binding protein A10 | 0.00531914 |
| TARDBP | TAR DNA binding protein | 0.00529568 |
| REG1A | regenerating islet-derived 1 alpha | 0.00529212 |
| MICALL1 | MICAL-like 1 | 0.00525673 |
| SATB2 | SATB homeobox 2 | 0.0052561 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00523212 |
| LAMB1 | laminin, beta 1 | 0.00522494 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00518453 |
| RAB6B | RAB6B, member RAS oncogene family | 0.00518045 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00511424 |
| HMGB3 | high mobility group box 3 | 0.00509484 |
| CENPE | centromere protein E, 312kDa | 0.00508995 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00507118 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00505972 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00505792 |
| CALR | calreticulin | 0.00505402 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00504509 |
| ARF3 | ADP-ribosylation factor 3 | 0.00502035 |
| HMGA1 | high mobility group AT-hook 1 | 0.00502027 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.0050141 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00499357 |
| PFKP | phosphofructokinase, platelet | 0.00499291 |
| PMEL | premelanosome protein | 0.00499012 |
| REG1B | regenerating islet-derived 1 beta | 0.00498606 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00498298 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | 0.00495461 |
| SHOX2 | short stature homeobox 2 | 0.00492774 |
| PCDH17 | protocadherin 17 | 0.0049213 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.0049066 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0049045 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00490338 |
| CHGA | chromogranin A | 0.00489443 |
| SQLE | squalene epoxidase | 0.0048924 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 | 0.00488119 |
| CD320 | CD320 molecule | 0.00485326 |
| JAG1 | jagged 1 | 0.00485267 |
| MTA1 | metastasis associated 1 | 0.00483066 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.00482626 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.0047971 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00479113 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00477393 |
| TSPAN12 | tetraspanin 12 | 0.00476194 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00475808 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00475245 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00474825 |
| EFNB2 | ephrin-B2 | 0.00470965 |
| WASF1 | WAS protein family, member 1 | 0.00470892 |
| OPN3 | opsin 3 | 0.00469068 |
| LOXL2 | lysyl oxidase-like 2 | 0.00468991 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.00468037 |
| DCT | dopachrome tautomerase | 0.00467916 |
| MINK1 | misshapen-like kinase 1 | 0.00465744 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00465139 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00464522 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00464073 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00461836 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00461479 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00461161 |
| PNKP | polynucleotide kinase 3'-phosphatase | 0.00461091 |
| NELL1 | NEL-like 1 (chicken) | 0.00459492 |
| ACKR3 | atypical chemokine receptor 3 | 0.00459209 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00458687 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00458493 |
| KRT8 | keratin 8, type II | 0.00457797 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.00457611 |
| DSP | desmoplakin | 0.00456533 |
| PEG10 | paternally expressed 10 | 0.00455605 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0045524 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.00454692 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00454423 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0045354 |
| GATA2 | GATA binding protein 2 | 0.00452869 |
| DIPK1A | divergent protein kinase domain 1A | 0.00451819 |
| FN1 | fibronectin 1 | 0.00451412 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00451383 |
| KIAA0930 | KIAA0930 | 0.00451352 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00450969 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00450867 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00449541 |
| CA2 | carbonic anhydrase II | 0.0044942 |
| EPHB2 | EPH receptor B2 | 0.0044878 |
| TRIM2 | tripartite motif containing 2 | 0.00448189 |
| ISL1 | ISL LIM homeobox 1 | 0.00447546 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00447239 |
| NUP107 | nucleoporin 107kDa | 0.00446245 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00443971 |
| SEPTIN11 | septin 11 | 0.00443373 |
| PRAME | preferentially expressed antigen in melanoma | 0.0044265 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0044244 |
| BEX1 | brain expressed, X-linked 1 | 0.00441171 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00441102 |
| JUND | jun D proto-oncogene | 0.00440842 |
| FNBP1L | formin binding protein 1-like | 0.00440767 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00440462 |
| FLOT1 | flotillin 1 | 0.00440349 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.00440022 |
| CD53 | CD53 molecule | 0.00439851 |
| OLFML2A | olfactomedin-like 2A | 0.00439342 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00439028 |
| KIF1B | kinesin family member 1B | 0.00438915 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | 0.00438904 |
| WDR3 | WD repeat domain 3 | 0.00438551 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00437188 |
| FAAH | fatty acid amide hydrolase | 0.00435803 |
| NCOA2 | nuclear receptor coactivator 2 | 0.00435258 |
| ADM | adrenomedullin | 0.00434947 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.00434652 |
| DTX4 | deltex 4, E3 ubiquitin ligase | 0.00434508 |
| WWC3 | WWC family member 3 | 0.00434015 |
| NPTX1 | neuronal pentraxin I | 0.00433852 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) | 0.00433056 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 0.00433012 |
| FOXF2 | forkhead box F2 | 0.00432486 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 0.00430563 |
| FASN | fatty acid synthase | 0.00429415 |
| HAND1 | heart and neural crest derivatives expressed 1 | 0.00429116 |
| USP3 | ubiquitin specific peptidase 3 | 0.00427838 |
| VEGFA | vascular endothelial growth factor A | 0.00426738 |
| VASH1 | vasohibin 1 | 0.00425819 |
| COL5A3 | collagen, type V, alpha 3 | 0.00424947 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.00423712 |
| ATRN | attractin | 0.00423497 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00422987 |
| ELMO1 | engulfment and cell motility 1 | 0.0042207 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00420756 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00420714 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00419864 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00419201 |
| SNX10 | sorting nexin 10 | 0.00419175 |
| CTSV | cathepsin V | 0.00419109 |
| CDK2 | cyclin-dependent kinase 2 | 0.00418549 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | 0.00418501 |
| NEO1 | neogenin 1 | 0.00418289 |
| DENND4B | DENN/MADD domain containing 4B | 0.00418112 |
| EHD2 | EH-domain containing 2 | 0.00418083 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.00417951 |
| CD2AP | CD2-associated protein | 0.00417907 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.00417164 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.00417066 |
| ACP3 | acid phosphatase 3 | 0.00416916 |
| PLD3 | phospholipase D family, member 3 | 0.00416371 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00416128 |
| NELL2 | NEL-like 2 (chicken) | 0.00415679 |
| FOXD1 | forkhead box D1 | 0.00415356 |
| RAPGEF4 | Rap guanine nucleotide exchange factor (GEF) 4 | 0.00414731 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0041365 |
| RUVBL2 | RuvB-like AAA ATPase 2 | 0.00413378 |
| LXN | latexin | 0.00412806 |
| PRKCI | protein kinase C, iota | 0.00411709 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.00411357 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00410869 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0041039 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00408947 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00408694 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.00407856 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0040725 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.00406393 |
| CNTNAP2 | contactin associated protein-like 2 | 0.00405711 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00405114 |
| RGS20 | regulator of G-protein signaling 20 | 0.00404602 |
| LEFTY1 | left-right determination factor 1 | 0.00404456 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.00404076 |
| ZWINT | ZW10 interacting kinetochore protein | 0.00404035 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 | 0.00403521 |
| PCP4 | Purkinje cell protein 4 | 0.00402535 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.00402374 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00400802 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00400679 |
| TSPAN15 | tetraspanin 15 | 0.00400575 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0293378 |
| MYBPC1 | myosin binding protein C, slow type | -0.0160664 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.0146469 |
| TNNC1 | troponin C type 1 (slow) | -0.012647 |
| SLN | sarcolipin | -0.0124486 |
| TTN | titin | -0.0123964 |
| CKM | creatine kinase, muscle | -0.011869 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0117326 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.0115948 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.0114984 |
| S100P | S100 calcium binding protein P | -0.0112621 |
| CRYAB | crystallin, alpha B | -0.0110826 |
| KLHL41 | kelch-like family member 41 | -0.0108063 |
| MYOT | myotilin | -0.0105253 |
| FABP7 | fatty acid binding protein 7, brain | -0.0103783 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.0103471 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0101228 |
| TNNC2 | troponin C type 2 (fast) | -0.0100895 |
| MB | myoglobin | -0.0100511 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00982412 |
| SMPX | small muscle protein, X-linked | -0.00977479 |
| CCN2 | cellular communication network factor 2 | -0.00972864 |
| LTF | lactotransferrin | -0.00968937 |
| HOPX | HOP homeobox | -0.00966814 |
| CFH | complement factor H | -0.00950111 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00947788 |
| TPM3 | tropomyosin 3 | -0.00943867 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00939406 |
| COQ8A | coenzyme Q8A | -0.00902992 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00900549 |
| DCN | decorin | -0.00885597 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.0087799 |
| MT1X | metallothionein 1X | -0.00870976 |
| PEG3 | paternally expressed 3 | -0.00845105 |
| CFD | complement factor D (adipsin) | -0.00838493 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0081964 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00819295 |
| CTTN | cortactin | -0.00818963 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00815136 |
| MYOZ2 | myozenin 2 | -0.00813363 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00813355 |
| LYZ | lysozyme | -0.00809844 |
| MARCO | macrophage receptor with collagenous structure | -0.00792202 |
| MYOM2 | myomesin 2 | -0.00788791 |
| PON3 | paraoxonase 3 | -0.00783995 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00782486 |
| GUCY2C | guanylate cyclase 2C | -0.00771309 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00770701 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -0.0076665 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00766527 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00756975 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00755941 |
| ANXA10 | annexin A10 | -0.00746153 |
| HOMER1 | homer scaffolding protein 1 | -0.0074031 |
| MT1E | metallothionein 1E | -0.00740182 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00736049 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00732522 |
| IFI44 | interferon-induced protein 44 | -0.0072422 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00723951 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -0.00715961 |
| CHRDL1 | chordin-like 1 | -0.00712653 |
| MX1 | MX dynamin-like GTPase 1 | -0.00710505 |
| MT1H | metallothionein 1H | -0.00706508 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.0069255 |
| AGR2 | anterior gradient 2 | -0.00690617 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00686269 |
| HNMT | histamine N-methyltransferase | -0.00685032 |
| PQBP1 | polyglutamine binding protein 1 | -0.00684645 |
| C1ORF56 | chromosome 1 open reading frame 56 | -0.00680686 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | -0.00673158 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00663026 |
| ECM1 | extracellular matrix protein 1 | -0.00661816 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00657325 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00655358 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00649388 |
| TMC5 | transmembrane channel-like 5 | -0.00648832 |
| MT1F | metallothionein 1F | -0.00646213 |
| IL32 | interleukin 32 | -0.00645119 |
| ENO3 | enolase 3 (beta, muscle) | -0.00642873 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00640651 |
| MYBPC2 | myosin binding protein C, fast type | -0.00637025 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.00636341 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00634367 |
| TXNIP | thioredoxin interacting protein | -0.00632439 |
| LAMA2 | laminin, alpha 2 | -0.00630784 |
| NEBL | nebulette | -0.00630362 |
| AOX1 | aldehyde oxidase 1 | -0.00630024 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00624999 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00624897 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00624881 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.0062297 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00622494 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00621635 |
| TNNT3 | troponin T type 3 (skeletal, fast) | -0.00621201 |
| IFI44L | interferon-induced protein 44-like | -0.0062041 |
| GPM6B | glycoprotein M6B | -0.00619664 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.006153 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00611766 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00609481 |
| TCAP | titin-cap | -0.00607977 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -0.00607769 |
| TMEM100 | transmembrane protein 100 | -0.00607568 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00604763 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00602748 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00600219 |
| DIO2 | deiodinase, iodothyronine, type II | -0.0059981 |
| PPID | peptidylprolyl isomerase D | -0.00599357 |
| DES | desmin | -0.00594447 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00593001 |
| FBLN5 | fibulin 5 | -0.00591986 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0058787 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00587628 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.00585572 |
| SDC2 | syndecan 2 | -0.00585354 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00585235 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -0.00585185 |
| MYOZ1 | myozenin 1 | -0.00584307 |
| ZNF586 | zinc finger protein 586 | -0.00583944 |
| GLTP | glycolipid transfer protein | -0.00582872 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00582258 |
| CLIC3 | chloride intracellular channel 3 | -0.00581659 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00581055 |
| HBB | hemoglobin, beta | -0.0058079 |
| WIF1 | WNT inhibitory factor 1 | -0.00573539 |
| ZNF426 | zinc finger protein 426 | -0.00572576 |
| MALL | mal, T-cell differentiation protein-like | -0.00572031 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00566644 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00565499 |
| CD52 | CD52 molecule | -0.00564393 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | -0.00562379 |
| FHL1 | four and a half LIM domains 1 | -0.00558532 |
| MT1G | metallothionein 1G | -0.005569 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00556355 |
| DIXDC1 | DIX domain containing 1 | -0.00555193 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00554363 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00553937 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00553348 |
| STON1 | stonin 1 | -0.00553316 |
| PUDP | pseudouridine 5'-phosphatase | -0.00553273 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.0055318 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00551701 |
| FERMT1 | fermitin family member 1 | -0.00551402 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00548747 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.00547844 |
| OSMR | oncostatin M receptor | -0.00547418 |
| HOXC6 | homeobox C6 | -0.00544484 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00544102 |
| ANOS1 | anosmin 1 | -0.00543726 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00542674 |
| METRN | meteorin, glial cell differentiation regulator | -0.0054124 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00540739 |
| POPDC3 | popeye domain containing 3 | -0.0054068 |
| CA3 | carbonic anhydrase III | -0.00539609 |
| MGP | matrix Gla protein | -0.00538575 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00534725 |
| S100A12 | S100 calcium binding protein A12 | -0.00534689 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00534472 |
| C4BPA | complement component 4 binding protein, alpha | -0.00534385 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.00533508 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.00533465 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00531824 |
| MAP7 | microtubule-associated protein 7 | -0.00531749 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00531442 |
| ORM1 | orosomucoid 1 | -0.00531073 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.00527832 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00527065 |
| HBD | hemoglobin, delta | -0.00525269 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 | -0.00524123 |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta | -0.0052319 |
| IL1RN | interleukin 1 receptor antagonist | -0.00522968 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00522638 |
| EDF1 | endothelial differentiation-related factor 1 | -0.00522612 |
| ACTN2 | actinin, alpha 2 | -0.00521805 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00521466 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00519941 |
| BARD1 | BRCA1 associated RING domain 1 | -0.00519556 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00519457 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00519304 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | -0.00517045 |
| TUBD1 | tubulin, delta 1 | -0.00516781 |
| LDB3 | LIM domain binding 3 | -0.00515742 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.0051548 |
| COPS7A | COP9 signalosome subunit 7A | -0.00510122 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | -0.00508804 |
| MAOB | monoamine oxidase B | -0.00508566 |
| MYLK | myosin light chain kinase | -0.00508028 |
| CSTA | cystatin A (stefin A) | -0.00507535 |
| PYGM | phosphorylase, glycogen, muscle | -0.00505609 |
| ANXA3 | annexin A3 | -0.00504125 |
| MED6 | mediator complex subunit 6 | -0.00502724 |
| G0S2 | G0/G1 switch 2 | -0.00502642 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00502375 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.00501584 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00501373 |
| ABLIM1 | actin binding LIM protein 1 | -0.00500427 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00496876 |
| GLUL | glutamate-ammonia ligase | -0.00496634 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) | -0.00496335 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00495198 |
| TRDN | triadin | -0.0049472 |
| CALCRL | calcitonin receptor-like | -0.0049444 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00494304 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0049407 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.00494062 |
| FGG | fibrinogen gamma chain | -0.00493904 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00492607 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00491473 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00491076 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00489155 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00488566 |
| TAGLN | transgelin | -0.00488236 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0048708 |
| AK1 | adenylate kinase 1 | -0.00487075 |
| RAB25 | RAB25, member RAS oncogene family | -0.00486601 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | -0.00486267 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00485315 |
| THBS4 | thrombospondin 4 | -0.00484426 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0048376 |
| TPM2 | tropomyosin 2 (beta) | -0.00482961 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00481091 |
| MME | membrane metallo-endopeptidase | -0.00480781 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00478835 |
| TSPAN1 | tetraspanin 1 | -0.004783 |
| DAPK1 | death-associated protein kinase 1 | -0.00477836 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.00477526 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00476451 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00475153 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 | -0.00471712 |
| FAM169A | family with sequence similarity 169, member A | -0.00471335 |
| ZNF652 | zinc finger protein 652 | -0.00471066 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa | -0.00470714 |
| TWF2 | twinfilin actin binding protein 2 | -0.0046824 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00468032 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00467199 |
| KLK11 | kallikrein-related peptidase 11 | -0.00467182 |
| FBN1 | fibrillin 1 | -0.00467026 |
| MT1M | metallothionein 1M | -0.0046586 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00464097 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00463218 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.00462438 |
| NRBF2 | nuclear receptor binding factor 2 | -0.00461254 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -0.0046044 |
| CD1B | CD1b molecule | -0.00459847 |
| ZNF106 | zinc finger protein 106 | -0.00459498 |
| PDAP1 | PDGFA associated protein 1 | -0.00458769 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00458069 |
| C4BPB | complement component 4 binding protein, beta | -0.00458009 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00457723 |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) | -0.0045744 |
