MAPK3 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description mitogen-activated protein kinase 3|The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5595)
External Link http://www.ncbi.nlm.nih.gov/gene/5595
Similar Terms
Downloads & Tools

Genes

320 interacting proteins for hub protein MAPK3 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ABI1 abl-interactor 1
ABLIM1 actin binding LIM protein 1
ADAM17 ADAM metallopeptidase domain 17
ADRBK1 adrenergic, beta, receptor kinase 1
AEBP1 AE binding protein 1
AGTR1 angiotensin II receptor, type 1
AKR1C1 aldo-keto reductase family 1, member C1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AR androgen receptor
ARHGAP31 Rho GTPase activating protein 31
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF2 activating transcription factor 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AVPR2 arginine vasopressin receptor 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCL9 B-cell CLL/lymphoma 9
BLVRA biliverdin reductase A
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSN bassoon presynaptic cytomatrix protein
BTG2 BTG family, member 2
C1QBP complement component 1, q subcomponent binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALD1 caldesmon 1
CANX calnexin
CAPN2 calpain 2, (m/II) large subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC6 coiled-coil domain containing 6
CDC25C cell division cycle 25C
CDCA5 cell division cycle associated 5
CDK2 cyclin-dependent kinase 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CIC capicua transcriptional repressor
CIITA class II, major histocompatibility complex, transactivator
CPXM1 carboxypeptidase X (M14 family), member 1
CRP C-reactive protein, pentraxin-related
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTTN cortactin
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DCC DCC netrin 1 receptor
DEAF1 DEAF1 transcription factor
DLG4 discs, large homolog 4 (Drosophila)
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP14 dual specificity phosphatase 14
DUSP16 dual specificity phosphatase 16
DUSP2 dual specificity phosphatase 2
DUSP26 dual specificity phosphatase 26 (putative)
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELK1 ELK1, member of ETS oncogene family
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EPOR erythropoietin receptor
EPS8 epidermal growth factor receptor pathway substrate 8
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV1 ets variant 1
ETV6 ets variant 6
EWSR1 EWS RNA-binding protein 1
FBXO4 F-box protein 4
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FKBP2 FK506 binding protein 2, 13kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO3 forkhead box O3
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GATAD2B GATA zinc finger domain containing 2B
GH1 growth hormone 1
GJA1 gap junction protein, alpha 1, 43kDa
GJD2 gap junction protein, delta 2, 36kDa
GMFB glia maturation factor, beta
GORASP2 golgi reassembly stacking protein 2, 55kDa
GRB10 growth factor receptor-bound protein 10
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3B glycogen synthase kinase 3 beta
GTF2I general transcription factor IIi
H3F3B H3 histone, family 3B (H3.3B)
HDAC4 histone deacetylase 4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSF1 heat shock transcription factor 1
HSF4 heat shock transcription factor 4
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB8 heat shock 22kDa protein 8
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IL16 interleukin 16
IL7R interleukin 7 receptor
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRX2 iroquois homeobox 2
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough
JUN jun proto-oncogene
JUND jun D proto-oncogene
KARS lysyl-tRNA synthetase
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KDM5A lysine (K)-specific demethylase 5A
KLC1 kinesin light chain 1
KRT8 keratin 8, type II
KSR1 kinase suppressor of ras 1
KSR2 kinase suppressor of ras 2
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LIFR leukemia inhibitory factor receptor alpha
LIPE lipase, hormone-sensitive
LMNA lamin A/C
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAGEA11 melanoma antigen family A11
MAP1B microtubule-associated protein 1B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MBP myelin basic protein
MCL1 myeloid cell leukemia 1
MED1 mediator complex subunit 1
METAP2 methionyl aminopeptidase 2
MITF microphthalmia-associated transcription factor
MKL1 megakaryoblastic leukemia (translocation) 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLK myosin light chain kinase
MYOCD myocardin
MZF1 myeloid zinc finger 1
NCF1 neutrophil cytosolic factor 1
NCKIPSD NCK interacting protein with SH3 domain
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NDEL1 nudE neurodevelopment protein 1-like 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEUROD1 neuronal differentiation 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NGFR nerve growth factor receptor
NOS2 nitric oxide synthase 2, inducible
NOXA1 NADPH oxidase activator 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP153 nucleoporin 153kDa
NUP214 nucleoporin 214kDa
NUP50 nucleoporin 50kDa
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAPOLA poly(A) polymerase alpha
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PEA15 phosphoprotein enriched in astrocytes 15
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PFKM phosphofructokinase, muscle
PGR progesterone receptor
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G10 phospholipase A2, group X
PLA2G12A phospholipase A2, group XIIA
PLA2G12B phospholipase A2, group XIIB
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2C phospholipase A2, group IIC
PLA2G2D phospholipase A2, group IID
PLA2G2E phospholipase A2, group IIE
PLA2G2F phospholipase A2, group IIF
PLA2G3 phospholipase A2, group III
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G4B phospholipase A2, group IVB (cytosolic)
PLA2G4E phospholipase A2, group IVE
PLA2G5 phospholipase A2, group V
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PML promyelocytic leukemia
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPARA peroxisome proliferator-activated receptor alpha
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCZ protein kinase C, zeta
PRKX protein kinase, X-linked
PRKY protein kinase, Y-linked, pseudogene
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRR protein tyrosine phosphatase, receptor type, R
PTTG1 pituitary tumor-transforming 1
PUF60 poly-U binding splicing factor 60KDa
PXN paxillin
RAB4A RAB4A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGDS ral guanine nucleotide dissociation stimulator
RANBP3 RAN binding protein 3
RARG retinoic acid receptor, gamma
RCAN1 regulator of calcineurin 1
RET ret proto-oncogene
RGS19 regulator of G-protein signaling 19
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS3 ribosomal protein S3
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RXRA retinoid X receptor, alpha
SCRIB scribbled planar cell polarity protein
SH2B1 SH2B adaptor protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNW1 SNW domain containing 1
SORBS3 sorbin and SH3 domain containing 3
SOS1 son of sevenless homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SQSTM1 sequestosome 1
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRRM2 serine/arginine repetitive matrix 2
STAB2 stabilin 2
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STMN1 stathmin 1
STMN2 stathmin 2
SULT4A1 sulfotransferase family 4A, member 1
SYK spleen tyrosine kinase
SYN1 synapsin I
SYN3 synapsin III
TAL1 T-cell acute lymphocytic leukemia 1
TAL2 T-cell acute lymphocytic leukemia 2
TCF3 transcription factor 3
TGIF1 TGFB-induced factor homeobox 1
TH tyrosine hydroxylase
THRB thyroid hormone receptor, beta
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOB1 transducer of ERBB2, 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TSC2 tuberous sclerosis 2
TTK TTK protein kinase
TTYH3 tweety family member 3
TWIST1 twist family bHLH transcription factor 1
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBTF upstream binding transcription factor, RNA polymerase I
ULK2 unc-51 like autophagy activating kinase 2
WASF2 WAS protein family, member 2
XPO6 exportin 6
ZFP36 ZFP36 ring finger protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZMYM3 zinc finger, MYM-type 3
ZNF7 zinc finger protein 7