| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | mitogen-activated protein kinase 3|The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5595) |
| External Link | https://ncbi.nlm.nih.gov/gene/5595 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the MAPK3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0119487 |
| KRT19 | keratin 19, type I | 0.0113444 |
| OLFM4 | olfactomedin 4 | 0.0110952 |
| CHGB | chromogranin B | 0.010078 |
| AGR2 | anterior gradient 2 | 0.00919743 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00919148 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00916968 |
| CDC20 | cell division cycle 20 | 0.00889779 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00875206 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00828226 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00810109 |
| PRKCZ | protein kinase C, zeta | 0.00806225 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00801368 |
| RGS5 | regulator of G-protein signaling 5 | 0.00785539 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00782541 |
| GPM6B | glycoprotein M6B | 0.00776932 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.0075897 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00749088 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00746651 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00743128 |
| DACH1 | dachshund family transcription factor 1 | 0.00731755 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00727953 |
| EPCAM | epithelial cell adhesion molecule | 0.00726956 |
| XIC | X chromosome inactivation center | 0.00725068 |
| TSPAN13 | tetraspanin 13 | 0.00715547 |
| S100P | S100 calcium binding protein P | 0.00715041 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00711066 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00688856 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00684273 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | 0.00682012 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00677442 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00675287 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0066871 |
| CADM1 | cell adhesion molecule 1 | 0.00667337 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.006655 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00661893 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00661021 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00658293 |
| MYO5C | myosin VC | 0.00656671 |
| SCG5 | secretogranin V | 0.00654474 |
| MSX1 | msh homeobox 1 | 0.00647363 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00640294 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | 0.00634709 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00631303 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.00630216 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00617926 |
| TCF4 | transcription factor 4 | 0.00616125 |
| COCH | cochlin | 0.00612694 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.0060712 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.00597699 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.00596936 |
| PEG3 | paternally expressed 3 | 0.00594998 |
| FBLN1 | fibulin 1 | 0.00594142 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.00592963 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00587446 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00584195 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0058222 |
| EDN3 | endothelin 3 | 0.00581327 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00579009 |
| CHN2 | chimerin 2 | 0.00577839 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0057614 |
| DESI1 | desumoylating isopeptidase 1 | 0.0057324 |
| GOLGA8A | golgin A8 family, member A | 0.00572332 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00570626 |
| DENND2D | DENN/MADD domain containing 2D | 0.00570285 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00569578 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00553476 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00553425 |
| TGM2 | transglutaminase 2 | 0.00553336 |
| CCDC92 | coiled-coil domain containing 92 | 0.00550903 |
| MGP | matrix Gla protein | 0.00548744 |
| APOD | apolipoprotein D | 0.0054787 |
| SYT1 | synaptotagmin I | 0.00547072 |
| OSR2 | odd-skipped related transciption factor 2 | 0.0054535 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00543158 |
| FHL1 | four and a half LIM domains 1 | 0.00542879 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0054215 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00541862 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00538867 |
| G0S2 | G0/G1 switch 2 | 0.00532958 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00532045 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00530411 |
| CERK | ceramide kinase | 0.00529997 |
| NEFH | neurofilament, heavy polypeptide | 0.00529701 |
| MYBPC1 | myosin binding protein C, slow type | 0.00523135 |
| STK26 | serine/threonine protein kinase 26 | 0.00521342 |
| CEP57 | centrosomal protein 57kDa | 0.00519512 |
| CST1 | cystatin SN | 0.00519407 |
| PRDX2 | peroxiredoxin 2 | 0.00518623 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00516905 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00513463 |
| OGN | osteoglycin | 0.00513121 |
| CFD | complement factor D (adipsin) | 0.00512744 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00512536 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00509902 |
| CTSZ | cathepsin Z | 0.00509857 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00507398 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00506333 |
| PLN | phospholamban | 0.00501173 |
| TBX3 | T-box 3 | 0.00499312 |
| SRPK2 | SRSF protein kinase 2 | 0.00498813 |
| MEIS2 | Meis homeobox 2 | 0.00494165 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.00493359 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00492083 |
| TPD52L1 | tumor protein D52-like 1 | 0.00491607 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00490864 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00489967 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00489163 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.0048751 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00485478 |
| CST3 | cystatin C | 0.00485224 |
| CAPN3 | calpain 3, (p94) | 0.00483193 |
| EFHD2 | EF-hand domain family, member D2 | 0.00481115 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00480413 |
| JAM3 | junctional adhesion molecule 3 | 0.00480264 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.00478505 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00477087 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00476844 |
| DES | desmin | 0.00476012 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00474374 |
| FGL2 | fibrinogen-like 2 | 0.00472255 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00471363 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00469727 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00467218 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00467092 |
| HEPH | hephaestin | 0.00466061 |
| WDR7 | WD repeat domain 7 | 0.00465817 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.00461876 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.00460833 |
| TRRAP | transformation/transcription domain-associated protein | 0.0046083 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00460111 |
| CCND2 | cyclin D2 | 0.00459437 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00450769 |
| MAOB | monoamine oxidase B | 0.00449964 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00447483 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00447371 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00447137 |
| CHRDL1 | chordin-like 1 | 0.00444837 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00444348 |
| CHGA | chromogranin A | 0.00443968 |
| PRSS3 | protease, serine, 3 | 0.00443902 |
| MPZL2 | myelin protein zero-like 2 | 0.00442505 |
| CAPN6 | calpain 6 | 0.00438995 |
| SIDT1 | SID1 transmembrane family, member 1 | 0.00438642 |
| LDB3 | LIM domain binding 3 | 0.00437945 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.00435563 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 0.00434709 |
| STX18 | syntaxin 18 | 0.00433721 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 0.0043325 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0043323 |
| REG1A | regenerating islet-derived 1 alpha | 0.0043301 |
| THYN1 | thymocyte nuclear protein 1 | 0.00433003 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.00432501 |
| REG3A | regenerating islet-derived 3 alpha | 0.00431773 |
| MYT1L | myelin transcription factor 1-like | 0.00431769 |
| FZD10 | frizzled class receptor 10 | 0.00431136 |
| TPD52L2 | tumor protein D52-like 2 | 0.00430834 |
| TCAF1 | TRPM8 channel-associated factor 1 | 0.00429854 |
| DPT | dermatopontin | 0.00429165 |
| SI | sucrase-isomaltase (alpha-glucosidase) | 0.00428323 |
| PDGFC | platelet derived growth factor C | 0.00428169 |
| KIF14 | kinesin family member 14 | 0.00426236 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00423177 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.00422924 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00422458 |
| CENPX | centromere protein X | 0.00421125 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00420705 |
| NPTN | neuroplastin | 0.00418017 |
| NEK2 | NIMA-related kinase 2 | 0.00416711 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00414695 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00414403 |
| CTSH | cathepsin H | 0.00414384 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00412275 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0041223 |
| SNX1 | sorting nexin 1 | 0.00411717 |
| RBM47 | RNA binding motif protein 47 | 0.00410675 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00409059 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | 0.00407874 |
| NELL2 | NEL-like 2 (chicken) | 0.00407435 |
| ANXA5 | annexin A5 | 0.0040732 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00406753 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00406258 |
| POU2AF1 | POU class 2 associating factor 1 | 0.004052 |
| XYLT1 | xylosyltransferase I | 0.00404953 |
| CDCP1 | CUB domain containing protein 1 | 0.00404718 |
| PALLD | palladin, cytoskeletal associated protein | 0.00404658 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00404144 |
| RAB40B | RAB40B, member RAS oncogene family | 0.004033 |
| ORC5 | origin recognition complex, subunit 5 | 0.00403199 |
| ZNF589 | zinc finger protein 589 | 0.00402904 |
| CUX1 | cut-like homeobox 1 | 0.00401162 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00400728 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00400333 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00398639 |
| USP48 | ubiquitin specific peptidase 48 | 0.00398345 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00398081 |
| TBC1D12 | TBC1 domain family, member 12 | 0.00396188 |
| C11ORF71 | chromosome 11 open reading frame 71 | 0.00395546 |
| CHKA | choline kinase alpha | 0.00395509 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00394934 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00393856 |
| CBX7 | chromobox homolog 7 | 0.00392394 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00391423 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00390745 |
| AGA | aspartylglucosaminidase | 0.00390348 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00389616 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00389462 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.00389242 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00388338 |
| AASDHPPT | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.00388257 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | 0.00387866 |
| RUNDC3B | RUN domain containing 3B | 0.00386145 |
| RGS2 | regulator of G-protein signaling 2 | 0.00385218 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00385144 |
| TMEM106B | transmembrane protein 106B | 0.00384493 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.00384465 |
| MXD4 | MAX dimerization protein 4 | 0.00383965 |
| CD44 | CD44 molecule (Indian blood group) | 0.00383778 |
| AHI1 | Abelson helper integration site 1 | 0.00382304 |
| H2AX | H2A.X variant histone | 0.00382216 |
| LZTFL1 | leucine zipper transcription factor-like 1 | 0.00381442 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.00381182 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00380547 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00380375 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 | 0.00379363 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00379215 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00378553 |
| CORO1C | coronin, actin binding protein, 1C | 0.00378033 |
| LIPG | lipase, endothelial | 0.00376829 |
| ING3 | inhibitor of growth family, member 3 | 0.00376776 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 0.00376747 |
| TRAPPC4 | trafficking protein particle complex 4 | 0.0037617 |
| LY75 | lymphocyte antigen 75 | 0.00375715 |
| COQ8A | coenzyme Q8A | 0.00374924 |
| MANSC1 | MANSC domain containing 1 | 0.00374819 |
| MAGEB2 | melanoma antigen family B2 | 0.00374289 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00374022 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00373556 |
| FAM3C | family with sequence similarity 3, member C | 0.00373394 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00372596 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0037196 |
| PREB | prolactin regulatory element binding | 0.00371916 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 0.00371734 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.00370982 |
| PSPC1 | paraspeckle component 1 | 0.0037086 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.0036993 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00369144 |
| GPX3 | glutathione peroxidase 3 | 0.0036901 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00368421 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.00368389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0111372 |
| LOX | lysyl oxidase | -0.0083348 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00807965 |
| DEFB1 | defensin, beta 1 | -0.00761342 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00758984 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00753769 |
| XPO7 | exportin 7 | -0.00741096 |
| THBS1 | thrombospondin 1 | -0.0074001 |
| OSMR | oncostatin M receptor | -0.00738583 |
| MVP | major vault protein | -0.00723965 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0071703 |
| KLK7 | kallikrein-related peptidase 7 | -0.00690477 |
| S100A8 | S100 calcium binding protein A8 | -0.00689317 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00687268 |
| NNMT | nicotinamide N-methyltransferase | -0.00684395 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00679918 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00678704 |
| S100A9 | S100 calcium binding protein A9 | -0.00673441 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0066991 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0066375 |
| MGLL | monoglyceride lipase | -0.00640449 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.0063308 |
| DOK5 | docking protein 5 | -0.00617467 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.00615619 |
| LY96 | lymphocyte antigen 96 | -0.00611013 |
| KLK10 | kallikrein-related peptidase 10 | -0.00609308 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00606452 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00605059 |
| COL5A1 | collagen, type V, alpha 1 | -0.00603394 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00596578 |
| KLK11 | kallikrein-related peptidase 11 | -0.00595949 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00595675 |
| UBB | ubiquitin B | -0.00581837 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00579853 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00578026 |
| PITX3 | paired-like homeodomain 3 | -0.00574902 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00564549 |
| DAPK1 | death-associated protein kinase 1 | -0.00563111 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00561409 |
| OXTR | oxytocin receptor | -0.00558036 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00557419 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00552701 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.00552598 |
| FGA | fibrinogen alpha chain | -0.00546553 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0054582 |
| CA12 | carbonic anhydrase XII | -0.00544054 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00543102 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00540057 |
| RGCC | regulator of cell cycle | -0.00534815 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00533903 |
| IL32 | interleukin 32 | -0.00533889 |
| PDZD2 | PDZ domain containing 2 | -0.00531996 |
| TLN1 | talin 1 | -0.0053174 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00530311 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00530113 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00526531 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00525738 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00524441 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00521874 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0051819 |
| BHMT | betaine--homocysteine S-methyltransferase | -0.00514909 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00514131 |
| NVL | nuclear VCP-like | -0.00513691 |
| SCEL | sciellin | -0.00509132 |
| ADM | adrenomedullin | -0.00508559 |
| CPA4 | carboxypeptidase A4 | -0.00507586 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00506743 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00501067 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00501049 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.0049994 |
| GSPT1 | G1 to S phase transition 1 | -0.00499698 |
| PXDN | peroxidasin | -0.00498724 |
| RRAGA | Ras-related GTP binding A | -0.00498687 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00498376 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00498332 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00495339 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00493346 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00492939 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00492733 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00490207 |
| CALR | calreticulin | -0.00488236 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00487432 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00485285 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.00485139 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00482045 |
| ARG1 | arginase 1 | -0.00481803 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.0048028 |
| F2R | coagulation factor II (thrombin) receptor | -0.00476978 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00476462 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.00475592 |
| TBXA2R | thromboxane A2 receptor | -0.00473033 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00472918 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00470087 |
| KRT1 | keratin 1, type II | -0.00470023 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00469387 |
| BID | BH3 interacting domain death agonist | -0.00467006 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00465962 |
| KLK8 | kallikrein-related peptidase 8 | -0.00464539 |
| CTSD | cathepsin D | -0.00463958 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | -0.00460017 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00456082 |
| PTGES | prostaglandin E synthase | -0.00455592 |
| CCNF | cyclin F | -0.00453065 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.0045295 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00452456 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.00452144 |
| FOLR1 | folate receptor 1 (adult) | -0.00452043 |
| RUNX1 | runt-related transcription factor 1 | -0.00451602 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -0.00451039 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00450869 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00450793 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00449972 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00448406 |
| IRX5 | iroquois homeobox 5 | -0.00448288 |
| THY1 | Thy-1 cell surface antigen | -0.00447718 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00446678 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | -0.00446614 |
| ANTXR1 | anthrax toxin receptor 1 | -0.00446419 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00445897 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00445711 |
| PRSS21 | protease, serine, 21 (testisin) | -0.0044559 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00443213 |
| POSTN | periostin, osteoblast specific factor | -0.00442454 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.00441195 |
| POPDC3 | popeye domain containing 3 | -0.00440798 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00439156 |
| IL24 | interleukin 24 | -0.00437791 |
| CD163 | CD163 molecule | -0.00435644 |
| NOX4 | NADPH oxidase 4 | -0.0043308 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00432081 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.0043149 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.0043135 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00430825 |
| HOXC10 | homeobox C10 | -0.00430727 |
| ZNF395 | zinc finger protein 395 | -0.00427986 |
| KCTD20 | potassium channel tetramerization domain containing 20 | -0.00427899 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00427738 |
| LST1 | leukocyte specific transcript 1 | -0.00425833 |
| ACTB | actin, beta | -0.00425686 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00425536 |
| ASS1 | argininosuccinate synthase 1 | -0.00424538 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.00422799 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.00422068 |
| PMM2 | phosphomannomutase 2 | -0.0042104 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00420983 |
| UPK1B | uroplakin 1B | -0.00420814 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00417855 |
| WT1 | Wilms tumor 1 | -0.00417752 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0041748 |
| CNN3 | calponin 3, acidic | -0.00417395 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.0041694 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00416412 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.0041487 |
| FMO1 | flavin containing monooxygenase 1 | -0.00414759 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | -0.00412402 |
| YIPF5 | Yip1 domain family, member 5 | -0.00411539 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | -0.00411336 |
| AIF1 | allograft inflammatory factor 1 | -0.0041086 |
| DPYS | dihydropyrimidinase | -0.00410688 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00410573 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00408185 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00407527 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00405715 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.00405177 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00405147 |
| CCKBR | cholecystokinin B receptor | -0.00402042 |
| GMFG | glia maturation factor, gamma | -0.00401986 |
| ORC1 | origin recognition complex, subunit 1 | -0.00401817 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00401777 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00401741 |
| TOR4A | torsin family 4, member A | -0.00401735 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.00401563 |
| FGB | fibrinogen beta chain | -0.00401336 |
| MRC2 | mannose receptor, C type 2 | -0.00401131 |
| SPP1 | secreted phosphoprotein 1 | -0.00400544 |
| THBS2 | thrombospondin 2 | -0.00398432 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00398403 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00397976 |
| TAGLN2 | transgelin 2 | -0.00397878 |
| IRS2 | insulin receptor substrate 2 | -0.00397277 |
| EXOC5 | exocyst complex component 5 | -0.00396585 |
| KRT17 | keratin 17, type I | -0.00396392 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | -0.00395443 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00392802 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00392671 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00388145 |
| CLDN1 | claudin 1 | -0.00386761 |
| MYO1B | myosin IB | -0.00386063 |
| CA2 | carbonic anhydrase II | -0.00385298 |
| CP | ceruloplasmin (ferroxidase) | -0.00385282 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00384644 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00384341 |
| KLF6 | Kruppel-like factor 6 | -0.00383054 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00382245 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.00382018 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00381917 |
| IFI44 | interferon-induced protein 44 | -0.00381547 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -0.0038145 |
| MEST | mesoderm specific transcript | -0.00381133 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.00381015 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00380569 |
| TFR2 | transferrin receptor 2 | -0.00380348 |
| EZR | ezrin | -0.0038019 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00380118 |
| TGM1 | transglutaminase 1 | -0.00379491 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.00379085 |
| OLFML2A | olfactomedin-like 2A | -0.00378517 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00378212 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00377342 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00375437 |
| TCTN2 | tectonic family member 2 | -0.00374955 |
| TRIM22 | tripartite motif containing 22 | -0.00373839 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00373703 |
| EPPK1 | epiplakin 1 | -0.00373043 |
| ZNF217 | zinc finger protein 217 | -0.00372244 |
| GDF15 | growth differentiation factor 15 | -0.00371964 |
| OPHN1 | oligophrenin 1 | -0.00368588 |
| PODXL | podocalyxin-like | -0.0036846 |
| TGFB1 | transforming growth factor, beta 1 | -0.00368428 |
| HCK | HCK proto-oncogene, Src family tyrosine kinase | -0.00367782 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00366338 |
| HIP1 | huntingtin interacting protein 1 | -0.00365346 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00364876 |
| SLFN12 | schlafen family member 12 | -0.00364132 |
| HSPE1 | heat shock 10kDa protein 1 | -0.00364015 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00363127 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00362901 |
| CDSN | corneodesmosin | -0.00361505 |
| EHD2 | EH-domain containing 2 | -0.00361054 |
| FJX1 | four jointed box 1 (Drosophila) | -0.00360949 |
| GTF2I | general transcription factor IIi | -0.00360499 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00360266 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.00360264 |
| HPX | hemopexin | -0.00358192 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00358093 |
| KLK12 | kallikrein-related peptidase 12 | -0.00356734 |
| LOXL2 | lysyl oxidase-like 2 | -0.00356723 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00356398 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00356002 |
| CDCA4 | cell division cycle associated 4 | -0.00355025 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00354132 |
| FAM198B | family with sequence similarity 198, member B | -0.0035392 |
| TLR4 | toll-like receptor 4 | -0.00353863 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0035311 |
| EREG | epiregulin | -0.00352242 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00352 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.00351252 |
| CBS | cystathionine-beta-synthase | -0.00350943 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0035078 |
