| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | mitogen-activated protein kinase 7|The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5598) |
| External Link | https://ncbi.nlm.nih.gov/gene/5598 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the MAPK7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0193422 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0189674 |
| IFI44L | interferon-induced protein 44-like | 0.0188783 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0171316 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.016725 |
| MX1 | MX dynamin-like GTPase 1 | 0.015258 |
| DEFB1 | defensin, beta 1 | 0.0150288 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.0134068 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.013312 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0131929 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0130831 |
| IFI44 | interferon-induced protein 44 | 0.0126414 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0125145 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.0120046 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0114777 |
| FN1 | fibronectin 1 | 0.0113896 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0110015 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0108063 |
| CD93 | CD93 molecule | 0.0107375 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0105925 |
| BST2 | bone marrow stromal cell antigen 2 | 0.010264 |
| S100A7 | S100 calcium binding protein A7 | 0.0101873 |
| AK4 | adenylate kinase 4 | 0.00992248 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0098599 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00982761 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00975902 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00974895 |
| S100A2 | S100 calcium binding protein A2 | 0.00974382 |
| MYO1B | myosin IB | 0.00965075 |
| RDX | radixin | 0.00956134 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00954716 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.00951999 |
| PALMD | palmdelphin | 0.00951223 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00945595 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00945562 |
| HNMT | histamine N-methyltransferase | 0.00927835 |
| MGP | matrix Gla protein | 0.00918431 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00908676 |
| NRN1 | neuritin 1 | 0.00907085 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00902085 |
| A2M | alpha-2-macroglobulin | 0.00898214 |
| KRT14 | keratin 14, type I | 0.00897626 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0088895 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00886749 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00879437 |
| CA2 | carbonic anhydrase II | 0.0086041 |
| IL1RN | interleukin 1 receptor antagonist | 0.00850821 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00845493 |
| CNN3 | calponin 3, acidic | 0.00844409 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00838947 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00827392 |
| REEP5 | receptor accessory protein 5 | 0.00811685 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00805985 |
| GPC3 | glypican 3 | 0.00802997 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00801235 |
| EFHD1 | EF-hand domain family, member D1 | 0.00800872 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00798823 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00797331 |
| ERGIC2 | ERGIC and golgi 2 | 0.00795565 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00791504 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0078622 |
| NVL | nuclear VCP-like | 0.00783101 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00782265 |
| NID1 | nidogen 1 | 0.00781446 |
| ASS1 | argininosuccinate synthase 1 | 0.00780651 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00776207 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.0077314 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00772229 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00768078 |
| ALB | albumin | 0.00767439 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00763495 |
| HLA-B | major histocompatibility complex, class I, B | 0.0075626 |
| CD99 | CD99 molecule | 0.00755074 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00753261 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00751411 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00748752 |
| RGCC | regulator of cell cycle | 0.00748638 |
| SPRR1B | small proline-rich protein 1B | 0.0074777 |
| S100A10 | S100 calcium binding protein A10 | 0.00746385 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00739088 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00735075 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.0073393 |
| CAV2 | caveolin 2 | 0.00728624 |
| KRT23 | keratin 23, type I | 0.00726397 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00722131 |
| MIA | melanoma inhibitory activity | 0.00720989 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00717896 |
| TRIM22 | tripartite motif containing 22 | 0.00717776 |
| CP | ceruloplasmin (ferroxidase) | 0.00713721 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.00713636 |
| APOD | apolipoprotein D | 0.00713065 |
| CALML5 | calmodulin-like 5 | 0.00705032 |
| MYO1C | myosin IC | 0.00702503 |
| MT1E | metallothionein 1E | 0.00700351 |
| EXOC5 | exocyst complex component 5 | 0.00699714 |
| HMBOX1 | homeobox containing 1 | 0.00698234 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00697114 |
| SNX10 | sorting nexin 10 | 0.00695562 |
| KLK11 | kallikrein-related peptidase 11 | 0.00693652 |
| MAOB | monoamine oxidase B | 0.00693213 |
| SP110 | SP110 nuclear body protein | 0.00692587 |
| LYST | lysosomal trafficking regulator | 0.0068902 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.0068876 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00688753 |
| LY96 | lymphocyte antigen 96 | 0.00685658 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00683706 |
| FGL2 | fibrinogen-like 2 | 0.0068346 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00679641 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0067571 |
| DAZAP2 | DAZ associated protein 2 | 0.00673627 |
| STC2 | stanniocalcin 2 | 0.00672457 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00672356 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00671597 |
| ZNF395 | zinc finger protein 395 | 0.00667562 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00666908 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00665468 |
| RAB38 | RAB38, member RAS oncogene family | 0.0066125 |
| NFIB | nuclear factor I/B | 0.00658588 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00657145 |
| TYRP1 | tyrosinase-related protein 1 | 0.00656396 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00655191 |
| CTTN | cortactin | 0.00652201 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00650973 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00650597 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00649939 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00648828 |
| ADI1 | acireductone dioxygenase 1 | 0.00646866 |
| BID | BH3 interacting domain death agonist | 0.00645803 |
| CSTA | cystatin A (stefin A) | 0.00642673 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.0064157 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.0064006 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00638863 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00635998 |
| ATF3 | activating transcription factor 3 | 0.00635859 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00635474 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00634584 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.00633972 |
| NEK7 | NIMA-related kinase 7 | 0.00633874 |
| PHF11 | PHD finger protein 11 | 0.00633794 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00633768 |
| EMCN | endomucin | 0.0063056 |
| TMEM140 | transmembrane protein 140 | 0.00628202 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.00627203 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00625078 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00623537 |
| FZD6 | frizzled class receptor 6 | 0.0062341 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00620672 |
| NCOA4 | nuclear receptor coactivator 4 | 0.00619143 |
| LST1 | leukocyte specific transcript 1 | 0.00617425 |
| CST6 | cystatin E/M | 0.00617038 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00616654 |
| XAF1 | XIAP associated factor 1 | 0.00616401 |
| MAL | mal, T-cell differentiation protein | 0.0061605 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00615541 |
| SMYD2 | SET and MYND domain containing 2 | 0.00614684 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00613797 |
| CRYAB | crystallin, alpha B | 0.00612923 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00610375 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00609911 |
| APOB | apolipoprotein B | 0.00608925 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00608911 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00607258 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00606124 |
| DCTN4 | dynactin 4 (p62) | 0.00602675 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00597891 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.005974 |
| APOA1 | apolipoprotein A-I | 0.00597047 |
| C3 | complement component 3 | 0.00593598 |
| H2AFV | H2A histone family, member V | 0.00592647 |
| LHFP | lipoma HMGIC fusion partner | 0.00589059 |
| MCAM | melanoma cell adhesion molecule | 0.00586877 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00586845 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00582873 |
| SAMHD1 | SAM domain and HD domain 1 | 0.00582076 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00580824 |
| APOL2 | apolipoprotein L, 2 | 0.00580792 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00579241 |
| KRT1 | keratin 1, type II | 0.00578984 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00578612 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.00577655 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00577507 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.005743 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00574124 |
| MT1G | metallothionein 1G | 0.00573936 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.00573815 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00573523 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00573435 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00571744 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00570606 |
| MT2A | metallothionein 2A | 0.00569915 |
| HAL | histidine ammonia-lyase | 0.00568865 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00568053 |
| CD52 | CD52 molecule | 0.00567588 |
| CDSN | corneodesmosin | 0.0056729 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00566302 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0056546 |
| TCTA | T-cell leukemia translocation altered | 0.00565324 |
| CANX | calnexin | 0.00565211 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00562435 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00562091 |
| DSP | desmoplakin | 0.00561986 |
| ESD | esterase D | 0.00560419 |
| KLK10 | kallikrein-related peptidase 10 | 0.00560419 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.00558136 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00558135 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00557818 |
| APOC2 | apolipoprotein C-II | 0.00557735 |
| EMP1 | epithelial membrane protein 1 | 0.00557118 |
| ENAH | enabled homolog (Drosophila) | 0.00556041 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00555916 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00555621 |
| SERINC5 | serine incorporator 5 | 0.00554967 |
| RLN1 | relaxin 1 | 0.00554861 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00554656 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.00552482 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00550855 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00550584 |
| XIC | X chromosome inactivation center | 0.00548281 |
| GHITM | growth hormone inducible transmembrane protein | 0.00547353 |
| MX2 | MX dynamin-like GTPase 2 | 0.00547158 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00547054 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00545223 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00545154 |
| EMP2 | epithelial membrane protein 2 | 0.0054451 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00542876 |
| TFRC | transferrin receptor | 0.00542664 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00542528 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00542111 |
| FAM110B | family with sequence similarity 110, member B | 0.00540154 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00540024 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.0053923 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00539064 |
| CFI | complement factor I | 0.00538573 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0053644 |
| CHN2 | chimerin 2 | 0.00536184 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.00535225 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00534054 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.00533603 |
| HLA-F | major histocompatibility complex, class I, F | 0.00533347 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00532803 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00532132 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.00530528 |
| USP18 | ubiquitin specific peptidase 18 | 0.00530449 |
| APOA2 | apolipoprotein A-II | 0.0053028 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.00529944 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.00528789 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00528331 |
| RRAD | Ras-related associated with diabetes | 0.00528163 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.00527626 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0052368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0318541 |
| TFF1 | trefoil factor 1 | -0.0192442 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0143659 |
| OLFM4 | olfactomedin 4 | -0.0141569 |
| AGR2 | anterior gradient 2 | -0.0134119 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.013119 |
| XYLT1 | xylosyltransferase I | -0.0126241 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0123585 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.011631 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0114663 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0112227 |
| FBN2 | fibrillin 2 | -0.0109786 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.010968 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0102535 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0100566 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0099689 |
| KRT19 | keratin 19, type I | -0.00994116 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00987893 |
| S100P | S100 calcium binding protein P | -0.00979737 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00966522 |
| KRT7 | keratin 7, type II | -0.00954337 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00949681 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00939441 |
| MMP7 | matrix metallopeptidase 7 | -0.00929642 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00928382 |
| PROM1 | prominin 1 | -0.00908572 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00906863 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00904236 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00893917 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00892224 |
| EFHD2 | EF-hand domain family, member D2 | -0.00892022 |
| LCN2 | lipocalin 2 | -0.00890472 |
| LOXL1 | lysyl oxidase-like 1 | -0.0087811 |
| NEBL | nebulette | -0.00859184 |
| TXLNA | taxilin alpha | -0.00855938 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00855437 |
| TSPAN12 | tetraspanin 12 | -0.00848877 |
| MARCKSL1 | MARCKS-like 1 | -0.00842155 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00841586 |
| MMP9 | matrix metallopeptidase 9 | -0.00840222 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00832144 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0082761 |
| NTS | neurotensin | -0.00826906 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00821408 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00820324 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00816465 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00806626 |
| NNMT | nicotinamide N-methyltransferase | -0.00806566 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.0080508 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00787398 |
| PRKD3 | protein kinase D3 | -0.0078569 |
| LXN | latexin | -0.00784446 |
| PCP4 | Purkinje cell protein 4 | -0.00782628 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00772541 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.00772196 |
| TESC | tescalcin | -0.00771694 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00769985 |
| RGS13 | regulator of G-protein signaling 13 | -0.00769963 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00768285 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00767702 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00764943 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00763484 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00763151 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00761882 |
| GAS1 | growth arrest-specific 1 | -0.00760242 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.00750374 |
| SIK1 | salt-inducible kinase 1 | -0.00741683 |
| FBXO11 | F-box protein 11 | -0.00740157 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00739543 |
| DACH1 | dachshund family transcription factor 1 | -0.00737306 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00735411 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -0.00734599 |
| EPHB2 | EPH receptor B2 | -0.00734089 |
| DGKZ | diacylglycerol kinase, zeta | -0.00729559 |
| HEPH | hephaestin | -0.00718992 |
| TSEN34 | TSEN34 tRNA splicing endonuclease subunit | -0.00713215 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00708073 |
| CHGB | chromogranin B | -0.00706795 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.00701325 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | -0.00691839 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00691064 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00689912 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00688853 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.00686397 |
| TBX3 | T-box 3 | -0.00685784 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00680317 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00680157 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0067899 |
| MID1 | midline 1 | -0.00673687 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.0067349 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00673174 |
| MTA1 | metastasis associated 1 | -0.00672076 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00670898 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00670878 |
| PFKM | phosphofructokinase, muscle | -0.00670228 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00666885 |
| COMP | cartilage oligomeric matrix protein | -0.00664528 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0066371 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00663534 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00661723 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00658762 |
| REG1B | regenerating islet-derived 1 beta | -0.00657305 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00656819 |
| PDGFD | platelet derived growth factor D | -0.00655203 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00654547 |
| AOC1 | amine oxidase, copper containing 1 | -0.00654527 |
| OLFM1 | olfactomedin 1 | -0.00651719 |
| NID2 | nidogen 2 (osteonidogen) | -0.00651487 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00647226 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00646741 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00640815 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00639334 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00639121 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00638695 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0063785 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00637169 |
| RRBP1 | ribosome binding protein 1 | -0.00636209 |
| REG1A | regenerating islet-derived 1 alpha | -0.00632505 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00631904 |
| PKM | pyruvate kinase, muscle | -0.00630219 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00629606 |
| TSPO | translocator protein (18kDa) | -0.00629184 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00629164 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.00628911 |
| KRT8 | keratin 8, type II | -0.00627875 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00625016 |
| LAMA5 | laminin, alpha 5 | -0.00623925 |
| BCOR | BCL6 corepressor | -0.00618977 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00618709 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.00618538 |
| PLXNC1 | plexin C1 | -0.00615314 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00615166 |
| SPATA20 | spermatogenesis associated 20 | -0.00614578 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00613546 |
| PLPP3 | phospholipid phosphatase 3 | -0.00613201 |
| ZNF329 | zinc finger protein 329 | -0.00610864 |
| LAMB1 | laminin, beta 1 | -0.00609967 |
| BLNK | B-cell linker | -0.00609193 |
| GALC | galactosylceramidase | -0.00606416 |
| CLCA1 | chloride channel accessory 1 | -0.00605959 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00604596 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00603378 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00601318 |
| NRXN2 | neurexin 2 | -0.00597459 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | -0.00596808 |
| SCG5 | secretogranin V | -0.00596468 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00595715 |
| CDR2L | cerebellar degeneration-related protein 2-like | -0.00595233 |
| MACROD1 | MACRO domain containing 1 | -0.00593262 |
| LMNB2 | lamin B2 | -0.00591056 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.005867 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00586641 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00584858 |
| MMP12 | matrix metallopeptidase 12 | -0.00583923 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00583619 |
| FASN | fatty acid synthase | -0.00583351 |
| TRIM28 | tripartite motif containing 28 | -0.00583053 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00580885 |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 | -0.00580844 |
| TGFB1 | transforming growth factor, beta 1 | -0.00579438 |
| CAPN6 | calpain 6 | -0.00574228 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00572766 |
| IFT81 | intraflagellar transport 81 | -0.00570785 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00569646 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00567767 |
| APMAP | adipocyte plasma membrane associated protein | -0.00566346 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.005658 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00565746 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00563886 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00562898 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -0.00562457 |
| ZNF586 | zinc finger protein 586 | -0.00559978 |
| ISOC2 | isochorismatase domain containing 2 | -0.0055979 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00559774 |
| NOTCH2 | notch 2 | -0.00559765 |
| REG3A | regenerating islet-derived 3 alpha | -0.00559083 |
| PTCH1 | patched 1 | -0.00555757 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -0.00554426 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00553391 |
| TPM2 | tropomyosin 2 (beta) | -0.00552645 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.00552548 |
| CLU | clusterin | -0.00552534 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00552409 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -0.00551304 |
| STX1A | syntaxin 1A (brain) | -0.00548699 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00548028 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00547408 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00547061 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00546071 |
| PDZD8 | PDZ domain containing 8 | -0.00545815 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00544592 |
| FJX1 | four jointed box 1 (Drosophila) | -0.00543717 |
| TLE4 | transducin-like enhancer of split 4 | -0.00543311 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00542597 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | -0.00541971 |
| MAGEA3 | melanoma antigen family A3 | -0.00541326 |
| IFT27 | intraflagellar transport 27 | -0.00538997 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00536614 |
| GPX2 | glutathione peroxidase 2 | -0.00535773 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.0053535 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00534672 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00534583 |
| TULP4 | tubby like protein 4 | -0.0053377 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00532373 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -0.00532318 |
| LYZ | lysozyme | -0.00530667 |
| PNKP | polynucleotide kinase 3'-phosphatase | -0.00529155 |
| AHI1 | Abelson helper integration site 1 | -0.00528946 |
| DUSP2 | dual specificity phosphatase 2 | -0.00528943 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00528145 |
| DNM1 | dynamin 1 | -0.00525624 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00524975 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00524909 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00522633 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00522416 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00522129 |
| TSPAN13 | tetraspanin 13 | -0.00520281 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00519273 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | -0.00518851 |
| SHOX2 | short stature homeobox 2 | -0.00517951 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00517111 |
| RAB11A | RAB11A, member RAS oncogene family | -0.00516567 |
| RNF19B | ring finger protein 19B | -0.00516458 |
| SAFB2 | scaffold attachment factor B2 | -0.00515115 |
| KIAA0125 | KIAA0125 | -0.00514471 |
| EFNB2 | ephrin-B2 | -0.00513864 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00513765 |
| ANGPT1 | angiopoietin 1 | -0.00513256 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.00512027 |
| TRH | thyrotropin-releasing hormone | -0.00511307 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00510677 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00510311 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00510219 |
| SELENBP1 | selenium binding protein 1 | -0.00507614 |
| ATG2A | autophagy related 2A | -0.00507228 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00506168 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00505216 |
| CD81 | CD81 molecule | -0.00505171 |
| KRT20 | keratin 20, type I | -0.00504037 |
| HIRA | histone cell cycle regulator | -0.00502863 |
| GTPBP1 | GTP binding protein 1 | -0.00502349 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00500823 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00500357 |
| ATP13A2 | ATPase type 13A2 | -0.00496323 |
| LEFTY1 | left-right determination factor 1 | -0.00496273 |
| NPTX2 | neuronal pentraxin II | -0.00495661 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00494927 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00494911 |
| CCDC92 | coiled-coil domain containing 92 | -0.00494269 |
