MAPKAPK2 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description mitogen-activated protein kinase-activated protein kinase 2|This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9261)
External Link http://www.ncbi.nlm.nih.gov/gene/9261
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Genes

39 substrates of the kinase MAPKAPK2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
AGO2 argonaute RISC catalytic component 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX5 arachidonate 5-lipoxygenase
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
BAG2 BCL2-associated athanogene 2
BCL2L1 BCL2-like 1
BECN1 beclin 1, autophagy related
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CREB1 cAMP responsive element binding protein 1
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
EEF2K eukaryotic elongation factor 2 kinase
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HSF1 heat shock transcription factor 1
HSPB1 heat shock 27kDa protein 1
KRT18 keratin 18, type I
KRT20 keratin 20, type I
LIMK1 LIM domain kinase 1
LPCAT2 lysophosphatidylcholine acyltransferase 2
LSP1 lymphocyte-specific protein 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
PARN poly(A)-specific ribonuclease
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIAS1 protein inhibitor of activated STAT, 1
PLK1 polo-like kinase 1
RCSD1 RCSD domain containing 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RTN4 reticulon 4
SRF serum response factor (c-fos serum response element-binding transcription factor)
TH tyrosine hydroxylase
TP53 tumor protein p53
TRIM28 tripartite motif containing 28
TRIM29 tripartite motif containing 29
TSC2 tuberous sclerosis 2
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFP36 ZFP36 ring finger protein
ZFP36L1 ZFP36 ring finger protein-like 1