MAPKAPK5 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mitogen-activated protein kinase-activated protein kinase 5|The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012] (NCBI Entrez Gene Database, 8550)
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Genes

381 genes differentially expressed following the MAPKAPK5 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NLRC3 NLR family, CARD domain containing 3 2.81041
IFITM10 interferon induced transmembrane protein 10 2.81041
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 2.81041
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.81041
S100A2 S100 calcium binding protein A2 2.81041
IRGM immunity-related GTPase family, M 2.81041
MEOX1 mesenchyme homeobox 1 2.81041
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 2.81041
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 2.81041
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.81041
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.81041
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.81041
MGAT4D MGAT4 family, member D 2.81041
C1QTNF1 C1q and tumor necrosis factor related protein 1 2.81041
FAM161B family with sequence similarity 161, member B 2.81041
CXCR6 chemokine (C-X-C motif) receptor 6 2.81041
HES7 hes family bHLH transcription factor 7 2.81041
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.81041
PLA2G4B phospholipase A2, group IVB (cytosolic) 2.81041
UPK1B uroplakin 1B 2.81041
RAPSN receptor-associated protein of the synapse 2.81041
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.81041
LRRIQ3 leucine-rich repeats and IQ motif containing 3 2.81041
LOC124903233 uncharacterized LOC124903233 2.81041
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 2.81041
TSPAN19 tetraspanin 19 2.81041
H4C12 H4 clustered histone 12 2.81041
PADI3 peptidyl arginine deiminase, type III 2.81041
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.6722
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 2.6722
CAPN11 calpain 11 2.6722
CD79B CD79b molecule, immunoglobulin-associated beta 2.6722
E2F3 E2F transcription factor 3 2.6722
HPR haptoglobin-related protein 2.6722
ZNF98 zinc finger protein 98 2.6722
KLHL31 kelch-like family member 31 2.6722
WNT11 wingless-type MMTV integration site family, member 11 2.6722
CHRD chordin 2.6722
PTGDR2 prostaglandin D2 receptor 2 2.6722
OR2A5 olfactory receptor, family 2, subfamily A, member 5 2.6722
RS1 retinoschisin 1 2.6722
FAM153A family with sequence similarity 153, member A 2.6722
PLVAP plasmalemma vesicle associated protein 2.6722
CLEC19A C-type lectin domain family 19, member A 2.6722
OR10A2 olfactory receptor, family 10, subfamily A, member 2 2.6722
VSTM2A V-set and transmembrane domain containing 2A 2.6722
CCL5 chemokine (C-C motif) ligand 5 2.6722
AADACL4 arylacetamide deacetylase-like 4 2.6722
ASB10 ankyrin repeat and SOCS box containing 10 2.6722
TUBB8 tubulin, beta 8 class VIII 2.6722
SCNN1G sodium channel, non voltage gated 1 gamma subunit 2.6722
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.6722
TAS2R1 taste receptor, type 2, member 1 2.6722
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.6722
FOXA1 forkhead box A1 2.6722
MUC1 mucin 1, cell surface associated 2.6722
NDRG1 N-myc downstream regulated 1 2.6722
FER1L6 fer-1-like family member 6 2.6722
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.6722
SIX3 SIX homeobox 3 2.6722
KNG1 kininogen 1 2.6722
TMPRSS11D transmembrane protease, serine 11D 2.6722
CDH5 cadherin 5, type 2 (vascular endothelium) 2.6722
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 2.6722
SACK1A scaffolding CK1 anchoring protein A 2.6722
SPINK1 serine peptidase inhibitor, Kazal type 1 2.6722
ANKRD34A ankyrin repeat domain 34A 2.6722
SPMIP11 sperm microtubule inner protein 11 2.6722
CATSPERZ catsper channel auxiliary subunit zeta 2.6722
SPACDR sperm acrosome developmental regulator 2.6722
SLC49A3 solute carrier family 49 member 3 2.6722
VPS50 VPS50 subunit of EARP/GARPII complex 2.6722
NSG2 neuronal vesicle trafficking associated 2 2.6722
EPOP elongin BC and polycomb repressive complex 2 associated protein 2.6722
ACP3 acid phosphatase 3 2.6722
PNMA8B PNMA family member 8B 2.6722
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 2.6722
LTB4R2 leukotriene B4 receptor 2 2.6722
H2BC11 H2B clustered histone 11 2.6722
TMEM225B transmembrane protein 225B 2.6722
MUCL3 mucin like 3 2.6722
SPMIP1 sperm microtubule inner protein 1 2.6722
CIMIP2A ciliary microtubule inner protein 2A 2.6722
CIMIP7 ciliary microtubule inner protein 7 2.6722
EXOC1L exocyst complex component 1 like 2.6722
FAM240A family with sequence similarity 240 member A 2.6722
CSP2 CS pseudogene 2 2.6722
LOC124906010 uncharacterized LOC124906010 2.6722
INSYN1 inhibitory synaptic factor 1 2.6722
PVALEF parvalbumin like EF-hand containing 2.6722
MYMK myomaker, myoblast fusion factor 2.6722
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 2.6722
VN1R1 vomeronasal 1 receptor 1 2.6722
ADGRG3 adhesion G protein-coupled receptor G3 2.6722
LTA lymphotoxin alpha 2.6722
FAM90A24 family with sequence similarity 90 member A24 2.6722
OVOL1 ovo-like zinc finger 1 2.6722
GJD2 gap junction protein, delta 2, 36kDa 2.6722
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.6722
CFAP45 cilia and flagella associated protein 45 2.6722
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.6722
IL5 interleukin 5 2.6722
MSX1 msh homeobox 1 2.6722
TMEM235 transmembrane protein 235 2.6722
CDKL4 cyclin-dependent kinase-like 4 2.6722
PARVG parvin, gamma 2.6722
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 2.6722
STX11 syntaxin 11 2.6722
FIMP1 fertilization-influencing membrane protein 1 2.6722
FMO1 flavin containing monooxygenase 1 2.6722
MLN motilin 2.6722
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 2.6722
TMPRSS6 transmembrane protease, serine 6 2.6722
MAGIX MAGI family member, X-linked 2.6722
TBX10 T-box 10 2.6722
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 2.6722
F5 coagulation factor V (proaccelerin, labile factor) 2.6722
CATSPERD catsper channel auxiliary subunit delta 2.6722
RHAG Rh-associated glycoprotein 2.6722
ONECUT3 one cut homeobox 3 2.6722
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.6722
DYTN dystrotelin 2.6722
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.6722
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.6722
ARL13A ADP-ribosylation factor-like 13A 2.6722
VAX2 ventral anterior homeobox 2 2.6722
KLK4 kallikrein-related peptidase 4 2.6722
RORC RAR-related orphan receptor C 2.6722
ANKRD33 ankyrin repeat domain 33 2.6722
LHX2 LIM homeobox 2 2.6722
APOL6 apolipoprotein L, 6 2.6722
NGB neuroglobin 2.6722
HMGB4 high mobility group box 4 2.6722
PATE2 prostate and testis expressed 2 2.6722
PLGLB1 plasminogen-like B1 2.6722
QRFP pyroglutamylated RFamide peptide 2.6722
CARD6 caspase recruitment domain family, member 6 2.6722
CARD9 caspase recruitment domain family, member 9 2.6722
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.6722
GAL3ST2 galactose-3-O-sulfotransferase 2 2.6722
CDHR4 cadherin-related family member 4 2.6722
FBXO40 F-box protein 40 2.6722
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.6722
CLEC4D C-type lectin domain family 4, member D 2.6722
POU2AF1 POU class 2 associating factor 1 2.6722
ISL1 ISL LIM homeobox 1 2.6722
EMILIN1 elastin microfibril interfacer 1 2.6722
CTSO cathepsin O 2.6722
CST1 cystatin SN 2.6722
C18ORF63 chromosome 18 open reading frame 63 2.6722
EDN1 endothelin 1 2.6722
FNDC9 fibronectin type III domain containing 9 2.6722
LRRC46 leucine rich repeat containing 46 2.6722
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.6722
MR1 major histocompatibility complex, class I-related 2.6722
RNF112 ring finger protein 112 2.6722
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.6722
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 2.6722
KLK7 kallikrein-related peptidase 7 2.6722
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 2.6722
LAMP3 lysosomal-associated membrane protein 3 2.6722
OR6A2 olfactory receptor, family 6, subfamily A, member 2 2.6722
MUC22 mucin 22 2.6722
TMEM255A transmembrane protein 255A 2.6722
RFX6 regulatory factor X, 6 2.6722
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.6722
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.6722
CCDC38 coiled-coil domain containing 38 2.6722
NLRP14 NLR family, pyrin domain containing 14 2.6722
MAGED4 melanoma antigen family D4 2.6722
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.6722
PARP10 poly (ADP-ribose) polymerase family, member 10 2.6722
LCN15 lipocalin 15 2.6722
TMEM217 transmembrane protein 217 2.6722
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.6722
TPM1 tropomyosin 1 (alpha) 2.6722
RPL3L ribosomal protein L3-like 2.6722
SFTPB surfactant protein B 2.6722
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.6722
TAS2R19 taste receptor, type 2, member 19 2.6722
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.6722
PCSK2 proprotein convertase subtilisin/kexin type 2 2.6722
GRM2 glutamate receptor, metabotropic 2 2.6722
LHX6 LIM homeobox 6 2.6722
CCDC83 coiled-coil domain containing 83 2.6722
ELP3 elongator acetyltransferase complex subunit 3 2.6722
ZPLD1 zona pellucida-like domain containing 1 2.6722
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.6722
TLDC2 TBC/LysM-associated domain containing 2 2.6722
OPALIN oligodendrocytic myelin paranodal and inner loop protein 2.6722
RTP3 receptor (chemosensory) transporter protein 3 2.6722
GBX2 gastrulation brain homeobox 2 2.6722
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.6722
EOMES eomesodermin 2.6722
LRRC38 leucine rich repeat containing 38 2.6722
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 2.6722
ANXA2R annexin A2 receptor 2.6722
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.64341
GMCL1 germ cell-less, spermatogenesis associated 1 2.61687
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.52234
SLITRK3 SLIT and NTRK-like family, member 3 2.52234
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 2.52234
KIAA2012 KIAA2012 2.52234
LIN7A lin-7 homolog A (C. elegans) 2.5127
DPPA2 developmental pluripotency associated 2 2.48949
MMP26 matrix metallopeptidase 26 2.48949
IL11RA interleukin 11 receptor, alpha 2.46253
FAM181B family with sequence similarity 181, member B 2.43711
TEAD4 TEA domain family member 4 2.40175
COL6A6 collagen, type VI, alpha 6 2.39528
H2BC5 H2B clustered histone 5 2.39528
RIPK4 receptor-interacting serine-threonine kinase 4 2.39387
NADK NAD kinase 2.38404
TFRC transferrin receptor 2.27509
NLK nemo-like kinase 2.20948
IDS iduronate 2-sulfatase 2.20448
RCAN2 regulator of calcineurin 2 2.19551
ANKRD26 ankyrin repeat domain 26 2.16937
PUM2 pumilio RNA-binding family member 2 2.15422
RUNX2 runt-related transcription factor 2 2.15422
TTC7B tetratricopeptide repeat domain 7B 2.13055
CEMIP2 cell migration inducing hyaluronidase 2 2.13055
UNC5C unc-5 homolog C (C. elegans) 2.12946
MYO9A myosin IXA 2.12661
TXK TXK tyrosine kinase 2.12661
PLK4 polo-like kinase 4 2.12661
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 2.11601
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.10374
PBX2 pre-B-cell leukemia homeobox 2 2.09734
ANO6 anoctamin 6 2.08346
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.06824
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 2.06748
ZNF33B zinc finger protein 33B 2.06438
MTF1 metal-regulatory transcription factor 1 2.06437
HEXD hexosaminidase D 2.05662
COQ10A coenzyme Q10 homolog A (S. cerevisiae) 2.0548

decreased expression

Symbol Name Standardized Value
ADCK5 aarF domain containing kinase 5 -2.81041
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.81041
BBS10 Bardet-Biedl syndrome 10 -2.81041
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -2.81041
DAP death-associated protein -2.81041
HEYL hes-related family bHLH transcription factor with YRPW motif-like -2.81041
ZCCHC4 zinc finger, CCHC domain containing 4 -2.81041
FOXL2 forkhead box L2 -2.81041
FAM222A family with sequence similarity 222, member A -2.81041
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.81041
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -2.6722
TMEM240 transmembrane protein 240 -2.6722
SCOC short coiled-coil protein -2.6722
KRTAP5-11 keratin associated protein 5-11 -2.6722
SLC46A1 solute carrier family 46 (folate transporter), member 1 -2.6722
GAGE10 G antigen 10 -2.6722
SSTR1 somatostatin receptor 1 -2.6722
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 -2.6722
HYAL3 hyaluronoglucosaminidase 3 -2.6722
PGM5 phosphoglucomutase 5 -2.6722
CD37 CD37 molecule -2.6722
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 -2.6722
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.6722
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B -2.6722
BMP8A bone morphogenetic protein 8a -2.6722
RGN regucalcin -2.6722
KIAA1755 KIAA1755 -2.6722
ADH6 alcohol dehydrogenase 6 (class V) -2.6722
ACOT12 acyl-CoA thioesterase 12 -2.6722
ICAM5 intercellular adhesion molecule 5, telencephalin -2.6722
ZNF717 zinc finger protein 717 -2.6722
DXO decapping exoribonuclease -2.6722
PNPLA5 patatin-like phospholipase domain containing 5 -2.6722
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G -2.6722
RAB27B RAB27B, member RAS oncogene family -2.6722
L2HGDH L-2-hydroxyglutarate dehydrogenase -2.6722
S100B S100 calcium binding protein B -2.6722
XKRX XK, Kell blood group complex subunit-related, X-linked -2.6722
RPL24 ribosomal protein L24 -2.6722
TBKBP1 TBK1 binding protein 1 -2.6722
PCDH20 protocadherin 20 -2.6722
COMMD3 COMM domain containing 3 -2.6722
ALX1 ALX homeobox 1 -2.6722
SEZ6L seizure related 6 homolog (mouse)-like -2.6722
BCL6B B-cell CLL/lymphoma 6, member B -2.6722
MAP4 microtubule-associated protein 4 -2.6722
S1PR1 sphingosine-1-phosphate receptor 1 -2.6722
HUS1B HUS1 checkpoint homolog b (S. pombe) -2.6722
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 -2.6722
TRIM68 tripartite motif containing 68 -2.6722
RPL14 ribosomal protein L14 -2.6722
TEKT3 tektin 3 -2.6722
SFRP1 secreted frizzled-related protein 1 -2.6722
GPR180 G protein-coupled receptor 180 -2.6722
KLK5 kallikrein-related peptidase 5 -2.6722
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -2.6722
UNG uracil-DNA glycosylase -2.6722
PRSS16 protease, serine, 16 (thymus) -2.66902
RPL37 ribosomal protein L37 -2.65662
MT1X metallothionein 1X -2.61537
ZNF391 zinc finger protein 391 -2.61006
TMEM186 transmembrane protein 186 -2.60745
CIAO2B cytosolic iron-sulfur assembly component 2B -2.55787
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.55787
SRSF9 serine/arginine-rich splicing factor 9 -2.54196
C19ORF18 chromosome 19 open reading frame 18 -2.52708
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.52135
SERINC5 serine incorporator 5 -2.4924
TARS1 threonyl-tRNA synthetase 1 -2.48949
FCRL5 Fc receptor-like 5 -2.47285
NRN1L neuritin 1-like -2.47285
FBL fibrillarin -2.47131
RPL7A ribosomal protein L7a -2.44733
CASP2 caspase 2, apoptosis-related cysteine peptidase -2.4413
IPO7 importin 7 -2.4413
CSNK1G2 casein kinase 1, gamma 2 -2.44067
MGAT4C MGAT4 family, member C -2.44016
RPL39 ribosomal protein L39 -2.4037
CARMIL2 capping protein regulator and myosin 1 linker 2 -2.39528
RPL12 ribosomal protein L12 -2.38597
PRDX3 peroxiredoxin 3 -2.3856
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.37798
MAPK6 mitogen-activated protein kinase 6 -2.35628
TTC7A tetratricopeptide repeat domain 7A -2.31707
RPL3 ribosomal protein L3 -2.30114
CEP192 centrosomal protein 192kDa -2.27914
CHMP4B charged multivesicular body protein 4B -2.27509
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -2.27509
AK4 adenylate kinase 4 -2.27509
RPS27 ribosomal protein S27 -2.25687
LSM12 LSM12 homolog (S. cerevisiae) -2.25487
CYTIP cytohesin 1 interacting protein -2.25286
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.25286
TMEM154 transmembrane protein 154 -2.25286
SLC35B1 solute carrier family 35, member B1 -2.21721
RPL28 ribosomal protein L28 -2.21117
CRTC2 CREB regulated transcription coactivator 2 -2.20948
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.20948
MYLK4 myosin light chain kinase family, member 4 -2.20948
IL17RE interleukin 17 receptor E -2.20948
TIMP4 TIMP metallopeptidase inhibitor 4 -2.20948
HAUS6 HAUS augmin-like complex, subunit 6 -2.20171
PPCS phosphopantothenoylcysteine synthetase -2.19235
ANK2 ankyrin 2, neuronal -2.19088
B3GAT2 beta-1,3-glucuronyltransferase 2 -2.17346
EDIL3 EGF-like repeats and discoidin I-like domains 3 -2.17176
LGALS3 lectin, galactoside-binding, soluble, 3 -2.16937
PRKG2 protein kinase, cGMP-dependent, type II -2.16687
PRELID3A PRELI domain containing 3A -2.15177
MRPS22 mitochondrial ribosomal protein S22 -2.14433
MRPL2 mitochondrial ribosomal protein L2 -2.13285
MIGA2 mitoguardin 2 -2.13285
PLD2 phospholipase D2 -2.13245
XRN1 5'-3' exoribonuclease 1 -2.13055
SLAIN2 SLAIN motif family, member 2 -2.13055
MRPL22 mitochondrial ribosomal protein L22 -2.13055
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2 -2.13055
MRPL9 mitochondrial ribosomal protein L9 -2.13055
ACTB actin, beta -2.13055
RNPS1 RNA binding protein S1, serine-rich domain -2.12803
SLC16A14 solute carrier family 16, member 14 -2.12803
TCHP trichoplein, keratin filament binding -2.12661
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -2.12201
EPHB2 EPH receptor B2 -2.10474
RACK1 receptor for activated C kinase 1 -2.09734
RPS7 ribosomal protein S7 -2.08117
MAP2K4 mitogen-activated protein kinase kinase 4 -2.07073
GAPDH glyceraldehyde-3-phosphate dehydrogenase -2.06824
ATL1 atlastin GTPase 1 -2.06748
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.06438
RPS28 ribosomal protein S28 -2.06437
EIF4A1 eukaryotic translation initiation factor 4A1 -2.06437
NUP58 nucleoporin 58 -2.05657
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.05657
CENPN centromere protein N -2.0548
FBXO42 F-box protein 42 -2.05385
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -2.05347
DEK DEK proto-oncogene -2.04626
FTCDNL1 formiminotransferase cyclodeaminase N-terminal like -2.04349
ANAPC7 anaphase promoting complex subunit 7 -2.03189
PPDPF pancreatic progenitor cell differentiation and proliferation factor -2.03189
CCT2 chaperonin containing TCP1, subunit 2 (beta) -2.03189
TMEM132A transmembrane protein 132A -2.02308
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.00449
PDE4D phosphodiesterase 4D, cAMP-specific -2.00379