MAPT Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description microtubule-associated protein tau|This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4137)
External Link https://ncbi.nlm.nih.gov/gene/4137
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Genes

499 genes differentially expressed following the MAPT gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0149724
SELENBP1 selenium binding protein 1 0.0136979
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.013555
STMN2 stathmin 2 0.0134581
PITX3 paired-like homeodomain 3 0.013364
TMPRSS4 transmembrane protease, serine 4 0.0129756
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.0125654
SNAP25 synaptosomal-associated protein, 25kDa 0.0123645
AOC1 amine oxidase, copper containing 1 0.0118104
BEX1 brain expressed, X-linked 1 0.011587
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.0112982
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.0112866
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.0112821
EMX2 empty spiracles homeobox 2 0.0112674
GJA1 gap junction protein, alpha 1, 43kDa 0.0112392
S100A9 S100 calcium binding protein A9 0.0111667
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0111547
WNT5A wingless-type MMTV integration site family, member 5A 0.010882
MXI1 MAX interactor 1, dimerization protein 0.0106478
NTS neurotensin 0.0105688
IFI27 interferon, alpha-inducible protein 27 0.0105563
VSNL1 visinin-like 1 0.0105359
VEGFA vascular endothelial growth factor A 0.0105229
RGCC regulator of cell cycle 0.0102702
ACKR3 atypical chemokine receptor 3 0.0101802
CA12 carbonic anhydrase XII 0.0101447
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.0100742
ASS1 argininosuccinate synthase 1 0.0100599
CCL20 chemokine (C-C motif) ligand 20 0.00995237
KDM5D lysine (K)-specific demethylase 5D 0.00991008
GPX2 glutathione peroxidase 2 0.00980263
STC1 stanniocalcin 1 0.00974772
CLCA4 chloride channel accessory 4 0.00973703
PRAME preferentially expressed antigen in melanoma 0.00948868
IGFBP4 insulin-like growth factor binding protein 4 0.00945054
PI3 peptidase inhibitor 3, skin-derived 0.00944612
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00934926
CSRP2 cysteine and glycine-rich protein 2 0.0091962
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00910142
MAOA monoamine oxidase A 0.00909502
FCGBP Fc fragment of IgG binding protein 0.00890468
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00884593
CST7 cystatin F (leukocystatin) 0.00881796
CXCL8 chemokine (C-X-C motif) ligand 8 0.00880614
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00880166
CFD complement factor D (adipsin) 0.00879427
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00877636
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00876688
DIPK1A divergent protein kinase domain 1A 0.00875244
C14ORF132 chromosome 14 open reading frame 132 0.00870604
ENO2 enolase 2 (gamma, neuronal) 0.00869875
RGS4 regulator of G-protein signaling 4 0.00868421
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00866598
ZIC1 Zic family member 1 0.00863974
HNMT histamine N-methyltransferase 0.00863121
EGR3 early growth response 3 0.00862068
AUTS2 autism susceptibility candidate 2 0.00852958
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00852297
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.0085069
SELE selectin E 0.00847525
STC2 stanniocalcin 2 0.00845628
FXYD3 FXYD domain containing ion transport regulator 3 0.00841453
NDRG1 N-myc downstream regulated 1 0.00831738
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00828808
PALLD palladin, cytoskeletal associated protein 0.0082593
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0082151
TUBB2A tubulin, beta 2A class IIa 0.00817494
KRT13 keratin 13, type I 0.00817344
KLK11 kallikrein-related peptidase 11 0.00812718
KLK10 kallikrein-related peptidase 10 0.00809289
NELL1 NEL-like 1 (chicken) 0.00800976
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00799983
DEFB1 defensin, beta 1 0.00798874
CXCL3 chemokine (C-X-C motif) ligand 3 0.00798387
MAB21L1 mab-21-like 1 (C. elegans) 0.0079471
PLPP3 phospholipid phosphatase 3 0.00792526
TOX3 TOX high mobility group box family member 3 0.0078477
BST2 bone marrow stromal cell antigen 2 0.00781803
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00781225
CSTA cystatin A (stefin A) 0.00779655
NMD3 NMD3 ribosome export adaptor 0.00778653
HILPDA hypoxia inducible lipid droplet-associated 0.00774483
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.007716
GRB7 growth factor receptor-bound protein 7 0.00767049
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00766358
TFF3 trefoil factor 3 (intestinal) 0.00763383
SMAD3 SMAD family member 3 0.00762419
HBB hemoglobin, beta 0.0076027
BCL3 B-cell CLL/lymphoma 3 0.00756703
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00752887
PENK proenkephalin 0.00750303
PLAT plasminogen activator, tissue 0.00749138
RGS10 regulator of G-protein signaling 10 0.00747156
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00744516
SPON2 spondin 2, extracellular matrix protein 0.00742312
CFDP1 craniofacial development protein 1 0.00741017
LAMA4 laminin, alpha 4 0.00740352
CD248 CD248 molecule, endosialin 0.00738466
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00737589
TMEM176B transmembrane protein 176B 0.00736764
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00735175
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00731691
ESR1 estrogen receptor 1 0.00731488
HOXB7 homeobox B7 0.00729443
IL1RN interleukin 1 receptor antagonist 0.00725864
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.00725738
PLBD1 phospholipase B domain containing 1 0.00725267
OSR2 odd-skipped related transciption factor 2 0.00724789
SORD sorbitol dehydrogenase 0.00723794
GATA2 GATA binding protein 2 0.00722331
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00720391
HOXB6 homeobox B6 0.00717569
MMP10 matrix metallopeptidase 10 0.00716905
ETHE1 ethylmalonic encephalopathy 1 0.00716536
MPPED2 metallophosphoesterase domain containing 2 0.0071086
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00710817
NRCAM neuronal cell adhesion molecule 0.00707744
S100A14 S100 calcium binding protein A14 0.00703043
MX2 MX dynamin-like GTPase 2 0.00701564
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00695894
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00694355
HCK HCK proto-oncogene, Src family tyrosine kinase 0.0069432
ADGRL2 adhesion G protein-coupled receptor L2 0.00694198
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.006935
ARL4A ADP-ribosylation factor-like 4A 0.00692537
XCL1 chemokine (C motif) ligand 1 0.0068973
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00688792
CRIP1 cysteine-rich protein 1 (intestinal) 0.00687673
CD69 CD69 molecule 0.00686365
BIRC3 baculoviral IAP repeat containing 3 0.00685694
COG7 component of oligomeric golgi complex 7 0.0068159
GPR183 G protein-coupled receptor 183 0.00679605
MAB21L2 mab-21-like 2 (C. elegans) 0.00679549
AK4 adenylate kinase 4 0.0067939
SPARCL1 SPARC-like 1 (hevin) 0.00679232
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00676581
NEBL nebulette 0.0067519
GPM6B glycoprotein M6B 0.00675147
ACOT7 acyl-CoA thioesterase 7 0.00674507
CD83 CD83 molecule 0.00674297
HOXB2 homeobox B2 0.006742
NEO1 neogenin 1 0.00670093
TICAM1 toll-like receptor adaptor molecule 1 0.00666858
PTPRO protein tyrosine phosphatase, receptor type, O 0.00666209
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00663984
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.00663155
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00660865
CXCL14 chemokine (C-X-C motif) ligand 14 0.00657776
CNN1 calponin 1, basic, smooth muscle 0.00657523
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00657471
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00655744
NEFH neurofilament, heavy polypeptide 0.00654754
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00652679
SYT1 synaptotagmin I 0.00648201
LAMP3 lysosomal-associated membrane protein 3 0.00645566
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00645486
CCL4 chemokine (C-C motif) ligand 4 0.00639838
ADM adrenomedullin 0.00639748
CRABP2 cellular retinoic acid binding protein 2 0.00639574
CXCL6 chemokine (C-X-C motif) ligand 6 0.00636685
XAF1 XIAP associated factor 1 0.00635825
OLFML3 olfactomedin-like 3 0.00634269
INA internexin neuronal intermediate filament protein, alpha 0.00633343
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00632063
APLP2 amyloid beta (A4) precursor-like protein 2 0.0063016
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00628999
RIMS3 regulating synaptic membrane exocytosis 3 0.00625243
CYB5A cytochrome b5 type A (microsomal) 0.00624758
PIR pirin (iron-binding nuclear protein) 0.00624251
GPM6A glycoprotein M6A 0.00623383
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00623375
COL4A5 collagen, type IV, alpha 5 0.00622642
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00621176
EHF ets homologous factor 0.00620031
SIAH2 siah E3 ubiquitin protein ligase 2 0.00619742
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00619252
DLD dihydrolipoamide dehydrogenase 0.00618323
C1ORF54 chromosome 1 open reading frame 54 0.00618195
PTHLH parathyroid hormone-like hormone 0.00617061
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00616018
FGF9 fibroblast growth factor 9 0.00615416
S100A12 S100 calcium binding protein A12 0.00610406
MEIS1 Meis homeobox 1 0.00610189
IGFBP6 insulin-like growth factor binding protein 6 0.00610072
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00609595
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00609429
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.00609029
GSE1 Gse1 coiled-coil protein 0.00606131
VWF von Willebrand factor 0.00606096
RB1 retinoblastoma 1 0.00605059
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0060319
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 0.00602895
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00601054
LY75 lymphocyte antigen 75 0.00600082
PTDSS1 phosphatidylserine synthase 1 0.00599125
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00598122
MID1IP1 MID1 interacting protein 1 0.00597968
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.00596346
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00593894
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00593594
RNH1 ribonuclease/angiogenin inhibitor 1 0.00593063
CRYBG1 crystallin beta-gamma domain containing 1 0.00591344
VCAM1 vascular cell adhesion molecule 1 0.00591331
TMPRSS2 transmembrane protease, serine 2 0.00590777
S100A8 S100 calcium binding protein A8 0.00589478
LY6D lymphocyte antigen 6 complex, locus D 0.00587236
NOTCH3 notch 3 0.00587149
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00587136
RNASET2 ribonuclease T2 0.00586818
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 0.0058634
CCL5 chemokine (C-C motif) ligand 5 0.0058614
TAC1 tachykinin, precursor 1 0.00585653
ACP3 acid phosphatase 3 0.00585617
MMP12 matrix metallopeptidase 12 0.00585411
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.00584833
SST somatostatin 0.00584109
CHEK2 checkpoint kinase 2 0.00583972
CCNG2 cyclin G2 0.0058284
XK X-linked Kx blood group 0.00582519
TRIOBP TRIO and F-actin binding protein 0.00581182
IFI6 interferon, alpha-inducible protein 6 0.00579833
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00578208
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00576094
KLK6 kallikrein-related peptidase 6 0.00573122
RAB25 RAB25, member RAS oncogene family 0.00573028
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00572683
TCAF1 TRPM8 channel-associated factor 1 0.00572602
DDT D-dopachrome tautomerase 0.00571054
IRF8 interferon regulatory factor 8 0.00570422
NCAM1 neural cell adhesion molecule 1 0.00569679
DUSP2 dual specificity phosphatase 2 0.00569434
GREB1 growth regulation by estrogen in breast cancer 1 0.00568684
INTS8 integrator complex subunit 8 0.00566715
TWIST1 twist family bHLH transcription factor 1 0.00564784
COLEC12 collectin sub-family member 12 0.00564398
BACE1 beta-site APP-cleaving enzyme 1 0.00563981
RHCG Rh family, C glycoprotein 0.005636
TGM2 transglutaminase 2 0.00563149
FBLN1 fibulin 1 0.00562495
CD177 CD177 molecule 0.00561754
PFKL phosphofructokinase, liver 0.00561138
SEPP1 selenoprotein P, plasma, 1 0.00561082
PCGF2 polycomb group ring finger 2 0.00560123
COL6A3 collagen, type VI, alpha 3 0.00559429
RNASE6 ribonuclease, RNase A family, k6 0.00559071
TMOD1 tropomodulin 1 0.00558044
CDK14 cyclin-dependent kinase 14 0.00557377
IFIH1 interferon induced with helicase C domain 1 0.00557031
CALB1 calbindin 1, 28kDa 0.00556888
SATB2 SATB homeobox 2 0.0055496

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -0.0232685
STK10 serine/threonine kinase 10 -0.0177843
GNAS GNAS complex locus -0.0130526
KRT7 keratin 7, type II -0.0126649
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0110621
MAP7 microtubule-associated protein 7 -0.0108255
CCN2 cellular communication network factor 2 -0.0104276
WASHC4 WASH complex subunit 4 -0.0103403
PXDN peroxidasin -0.0102686
MAGEA3 melanoma antigen family A3 -0.0102203
DAPK1 death-associated protein kinase 1 -0.00957109
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00956465
SCGB2A2 secretoglobin, family 2A, member 2 -0.00935203
BGN biglycan -0.00912822
SIRT3 sirtuin 3 -0.00909972
PLAAT3 phospholipase A and acyltransferase 3 -0.008869
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00871056
COL11A1 collagen, type XI, alpha 1 -0.00864107
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00824431
COL10A1 collagen, type X, alpha 1 -0.00801949
TYMS thymidylate synthetase -0.00799467
EPCAM epithelial cell adhesion molecule -0.00797878
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00796839
HSPA1A heat shock 70kDa protein 1A -0.00795788
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00793793
KIAA0100 KIAA0100 -0.00784091
TNIK TRAF2 and NCK interacting kinase -0.00783026
COL2A1 collagen, type II, alpha 1 -0.00777179
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.0077113
ABHD4 abhydrolase domain containing 4 -0.00767252
LPIN1 lipin 1 -0.00767031
FAM222B family with sequence similarity 222, member B -0.00766237
ANXA3 annexin A3 -0.00756082
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00739003
CD320 CD320 molecule -0.00738525
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.0073725
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00734537
PLXNC1 plexin C1 -0.007291
CCP110 centriolar coiled coil protein 110kDa -0.00721565
MZB1 marginal zone B and B1 cell-specific protein -0.00716349
CADM1 cell adhesion molecule 1 -0.00715659
TLCD3A TLC domain containing 3A -0.00710104
NT5DC2 5'-nucleotidase domain containing 2 -0.00709315
KRT18 keratin 18, type I -0.00707456
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.00706663
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00700973
BRD2 bromodomain containing 2 -0.00697212
MACROH2A1 macroH2A.1 histone -0.00694412
TSPAN13 tetraspanin 13 -0.00691198
CPB1 carboxypeptidase B1 (tissue) -0.00690041
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00688694
MAGEA12 melanoma antigen family A12 -0.00688217
VNN1 vanin 1 -0.00688181
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00688164
COQ8A coenzyme Q8A -0.00684486
TAGLN transgelin -0.00683782
ARHGAP29 Rho GTPase activating protein 29 -0.00683727
STAG3 stromal antigen 3 -0.00681632
LTF lactotransferrin -0.00677642
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00676395
MEF2C myocyte enhancer factor 2C -0.0067362
NKX2-1 NK2 homeobox 1 -0.00672168
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.00668452
ZBTB20 zinc finger and BTB domain containing 20 -0.00668078
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00666237
NKX2-2 NK2 homeobox 2 -0.00663839
CCND2 cyclin D2 -0.00658007
PXDC1 PX domain containing 1 -0.00656829
MAGEB2 melanoma antigen family B2 -0.0065029
ARMCX3 armadillo repeat containing, X-linked 3 -0.00649804
SIK1 salt-inducible kinase 1 -0.00649587
HHEX hematopoietically expressed homeobox -0.00645044
PCDH9 protocadherin 9 -0.00641109
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00639762
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00638346
KRT81 keratin 81, type II -0.0063819
SHMT1 serine hydroxymethyltransferase 1 (soluble) -0.00635937
TM4SF1 transmembrane 4 L six family member 1 -0.00635738
PNKP polynucleotide kinase 3'-phosphatase -0.00634591
TRAM1 translocation associated membrane protein 1 -0.00634239
XIC X chromosome inactivation center -0.00630392
NTM neurotrimin -0.00621058
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00620994
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00618759
PLIN2 perilipin 2 -0.00616408
CDCA4 cell division cycle associated 4 -0.00614542
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00609654
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00607681
ERGIC2 ERGIC and golgi 2 -0.0060623
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00606152
DHCR7 7-dehydrocholesterol reductase -0.00603971
ZBTB16 zinc finger and BTB domain containing 16 -0.0060373
PDLIM5 PDZ and LIM domain 5 -0.00602848
TTLL7 tubulin tyrosine ligase-like family member 7 -0.00601621
DUSP6 dual specificity phosphatase 6 -0.00601202
DCHS1 dachsous cadherin-related 1 -0.00600724
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00600665
CHMP6 charged multivesicular body protein 6 -0.00596364
CLTA clathrin, light chain A -0.00596127
MTF2 metal response element binding transcription factor 2 -0.00595539
IPO9 importin 9 -0.00594829
PRR11 proline rich 11 -0.00591934
PON3 paraoxonase 3 -0.00591339
RFTN1 raftlin, lipid raft linker 1 -0.00591284
ABHD6 abhydrolase domain containing 6 -0.00589817
TMEM230 transmembrane protein 230 -0.00586143
CRHBP corticotropin releasing hormone binding protein -0.00585999
KIF14 kinesin family member 14 -0.00585104
HRASLS HRAS-like suppressor -0.00584747
MERTK MER proto-oncogene, tyrosine kinase -0.00580466
LIPG lipase, endothelial -0.00580383
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -0.0057686
LMCD1 LIM and cysteine-rich domains 1 -0.00576721
RAN RAN, member RAS oncogene family -0.00576281
MFAP3L microfibrillar-associated protein 3-like -0.00573765
MRPS2 mitochondrial ribosomal protein S2 -0.00573413
ARMCX1 armadillo repeat containing, X-linked 1 -0.00572838
TPD52 tumor protein D52 -0.00572288
PNPLA6 patatin-like phospholipase domain containing 6 -0.00571767
G6PC3 glucose 6 phosphatase, catalytic, 3 -0.00571204
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00561897
SFTPB surfactant protein B -0.00561593
PLXND1 plexin D1 -0.00560101
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -0.00557728
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -0.00557067
DSE dermatan sulfate epimerase -0.0055706
FRZB frizzled-related protein -0.0055604
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.00554971
HAVCR1 hepatitis A virus cellular receptor 1 -0.00554795
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00554206
SFTPD surfactant protein D -0.00553068
NOP2 NOP2 nucleolar protein -0.00552602
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00551525
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00550166
FADS3 fatty acid desaturase 3 -0.00549054
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00548137
GLS glutaminase -0.00547803
ADGRF5 adhesion G protein-coupled receptor F5 -0.00546914
KANK1 KN motif and ankyrin repeat domains 1 -0.00546442
ELN elastin -0.00546055
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -0.00545129
NOP56 NOP56 ribonucleoprotein -0.00544745
INHBA inhibin, beta A -0.00544512
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -0.00543054
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -0.00541884
CENPU centromere protein U -0.00541851
PAWR PRKC, apoptosis, WT1, regulator -0.00541824
IPO13 importin 13 -0.00541617
TOMM34 translocase of outer mitochondrial membrane 34 -0.00541232
DDRGK1 DDRGK domain containing 1 -0.00541212
DNTT DNA nucleotidylexotransferase -0.00540978
C1ORF56 chromosome 1 open reading frame 56 -0.00540611
PWWP3A PWWP domain containing 3A, DNA repair factor -0.00539044
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00538471
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.00536836
C11ORF24 chromosome 11 open reading frame 24 -0.00536283
CCNA2 cyclin A2 -0.00535489
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -0.00532706
PERP PERP, TP53 apoptosis effector -0.00531226
ZMYND8 zinc finger, MYND-type containing 8 -0.00528386
TACSTD2 tumor-associated calcium signal transducer 2 -0.0052698
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00526565
CTSE cathepsin E -0.0052502
FEN1 flap structure-specific endonuclease 1 -0.00524799
RUFY3 RUN and FYVE domain containing 3 -0.00523379
SC5D sterol-C5-desaturase -0.00521859
FBLN5 fibulin 5 -0.0051937
SEC61B Sec61 beta subunit -0.00518186
CHKA choline kinase alpha -0.00516548
STAT4 signal transducer and activator of transcription 4 -0.00516027
HOPX HOP homeobox -0.00515124
RIN3 Ras and Rab interactor 3 -0.00514837
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 -0.0051408
CCDC92 coiled-coil domain containing 92 -0.00513961
SCGB1D2 secretoglobin, family 1D, member 2 -0.00513099
CLCN4 chloride channel, voltage-sensitive 4 -0.00512371
SFPQ splicing factor proline/glutamine-rich -0.00511821
MAP3K7CL MAP3K7 C-terminal like -0.00509582
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00509437
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00508871
SCN3A sodium channel, voltage gated, type III alpha subunit -0.00507559
STAB1 stabilin 1 -0.00507057
INAVA innate immunity activator -0.00507053
THBS2 thrombospondin 2 -0.0050596
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -0.00505852
KIF5B kinesin family member 5B -0.00505479
HYI hydroxypyruvate isomerase (putative) -0.0050511
MOK MOK protein kinase -0.00504549
FXYD5 FXYD domain containing ion transport regulator 5 -0.00503203
HMBOX1 homeobox containing 1 -0.00503127
CSRP1 cysteine and glycine-rich protein 1 -0.00501023
CTNS cystinosin, lysosomal cystine transporter -0.00500625
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.00500279
PDLIM3 PDZ and LIM domain 3 -0.00500114
CHPT1 choline phosphotransferase 1 -0.00499148
KLHL41 kelch-like family member 41 -0.00498538
NDE1 nudE neurodevelopment protein 1 -0.00497876
FKBP1A FK506 binding protein 1A, 12kDa -0.00497387
ALOX5 arachidonate 5-lipoxygenase -0.00496753
RBM26 RNA binding motif protein 26 -0.00495869
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00495179
ZNF160 zinc finger protein 160 -0.00494952
AMZ2 archaelysin family metallopeptidase 2 -0.00494171
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00493476
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00493042
RGS1 regulator of G-protein signaling 1 -0.00492338
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00492256
KLF6 Kruppel-like factor 6 -0.00491993
SERHL2 serine hydrolase-like 2 -0.00490937
C9 complement component 9 -0.00490587
CCL21 chemokine (C-C motif) ligand 21 -0.00490477
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00490291
GOLT1B golgi transport 1B -0.00489827
KIF16B kinesin family member 16B -0.0048977
GRB14 growth factor receptor-bound protein 14 -0.00488449
TMEM45A transmembrane protein 45A -0.00486152
SOX10 SRY (sex determining region Y)-box 10 -0.004853
FHL1 four and a half LIM domains 1 -0.00484859
SSX1 synovial sarcoma, X breakpoint 1 -0.00484122
HIP1R huntingtin interacting protein 1 related -0.00483938
CD163 CD163 molecule -0.00483618
IVD isovaleryl-CoA dehydrogenase -0.00483555
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -0.00483236
COBL cordon-bleu WH2 repeat protein -0.00482381
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -0.00481985
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00481637
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00480738
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -0.00480269
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00480211
PPP1R26 protein phosphatase 1, regulatory subunit 26 -0.00479624
FBXL12 F-box and leucine-rich repeat protein 12 -0.00478549
VAMP8 vesicle-associated membrane protein 8 -0.0047816
NELFCD negative elongation factor complex member C/D -0.00478032
FST follistatin -0.00476733
CLU clusterin -0.00476305
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00476256
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -0.00476033
KDSR 3-ketodihydrosphingosine reductase -0.0047602
GRHPR glyoxylate reductase/hydroxypyruvate reductase -0.00475759
ANKRD6 ankyrin repeat domain 6 -0.00475648
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00474357
MYO5C myosin VC -0.00473956
GOLM1 golgi membrane protein 1 -0.00473579
COPE coatomer protein complex, subunit epsilon -0.00472893
HELLS helicase, lymphoid-specific -0.0047228
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.00471727
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00471539
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00471135
NUDC nudC nuclear distribution protein -0.00470833