| Dataset | Pathway Commons Protein-Protein Interactions |
| Category | physical interactions |
| Type | interacting protein |
| Description | membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase|MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010] (NCBI Entrez Gene Database, 57574) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/57574 |
| Similar Terms | |
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4 interacting proteins for MARCH4 from the Pathway Commons Protein-Protein Interactions dataset.
