MARCO Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description macrophage receptor with collagenous structure|The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8685)
External Link https://ncbi.nlm.nih.gov/gene/8685
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Genes

498 genes differentially expressed following the MARCO gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LXN latexin 0.0169229
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0152944
NEBL nebulette 0.015097
S100P S100 calcium binding protein P 0.0143935
AREG amphiregulin 0.0140481
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0138887
MAP7 microtubule-associated protein 7 0.0137966
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0134985
ANXA1 annexin A1 0.0134755
PPARG peroxisome proliferator-activated receptor gamma 0.0130239
RCAN1 regulator of calcineurin 1 0.0130001
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.0118365
CXCL8 chemokine (C-X-C motif) ligand 8 0.0115917
SRPX2 sushi-repeat containing protein, X-linked 2 0.0113004
FXYD3 FXYD domain containing ion transport regulator 3 0.0111343
TMEM47 transmembrane protein 47 0.0110652
COBL cordon-bleu WH2 repeat protein 0.0108852
SPRR3 small proline-rich protein 3 0.0107547
FABP7 fatty acid binding protein 7, brain 0.0107393
HBB hemoglobin, beta 0.0107205
PADI2 peptidyl arginine deiminase, type II 0.010462
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0103382
TSPAN1 tetraspanin 1 0.0101296
PTK2 protein tyrosine kinase 2 0.0100045
GPX1 glutathione peroxidase 1 0.00996641
LTF lactotransferrin 0.00994494
SFRP4 secreted frizzled-related protein 4 0.00991274
STOM stomatin 0.00990914
EHF ets homologous factor 0.00989238
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00985034
MALL mal, T-cell differentiation protein-like 0.00983885
PDE4B phosphodiesterase 4B, cAMP-specific 0.00975515
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00970373
SPP1 secreted phosphoprotein 1 0.00969379
ADD3 adducin 3 (gamma) 0.00964139
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00943046
RGS1 regulator of G-protein signaling 1 0.00937828
KRT13 keratin 13, type I 0.00937783
EMP1 epithelial membrane protein 1 0.00933961
THBD thrombomodulin 0.00931349
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00919462
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00913977
VCAN versican 0.0091004
MNDA myeloid cell nuclear differentiation antigen 0.00909894
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00908893
C10ORF10 chromosome 10 open reading frame 10 0.00899011
CXCL5 chemokine (C-X-C motif) ligand 5 0.00888523
MMP12 matrix metallopeptidase 12 0.00887614
PTGES prostaglandin E synthase 0.00886678
KRT19 keratin 19, type I 0.00886208
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 0.00883799
KLK6 kallikrein-related peptidase 6 0.00881765
CLCA4 chloride channel accessory 4 0.00870353
NAMPT nicotinamide phosphoribosyltransferase 0.00863727
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00862683
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00862014
APOLD1 apolipoprotein L domain containing 1 0.0085989
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00857565
IGFBP6 insulin-like growth factor binding protein 6 0.00855227
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00842486
CEMIP cell migration inducing protein, hyaluronan binding 0.00842027
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00840638
SCEL sciellin 0.0083405
ZDHHC6 zinc finger, DHHC-type containing 6 0.00833495
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00833119
CD59 CD59 molecule, complement regulatory protein 0.00832569
TSC22D1 TSC22 domain family, member 1 0.00832386
CAPRIN1 cell cycle associated protein 1 0.00832296
EPCAM epithelial cell adhesion molecule 0.00832155
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00830764
NID2 nidogen 2 (osteonidogen) 0.00829141
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00826301
CSTA cystatin A (stefin A) 0.00825258
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00820475
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00816965
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00815378
SET SET nuclear proto-oncogene 0.00812034
NMRK1 nicotinamide riboside kinase 1 0.00807611
CLIC5 chloride intracellular channel 5 0.00805011
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00803005
C1S complement component 1, s subcomponent 0.00802926
POSTN periostin, osteoblast specific factor 0.00800107
THBS2 thrombospondin 2 0.00797996
AGTR1 angiotensin II receptor, type 1 0.0079709
S100A8 S100 calcium binding protein A8 0.00795764
NRN1 neuritin 1 0.00795469
BAMBI BMP and activin membrane-bound inhibitor 0.00794744
MAL mal, T-cell differentiation protein 0.00794498
BHLHE41 basic helix-loop-helix family, member e41 0.00793684
DLD dihydrolipoamide dehydrogenase 0.00793058
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00792046
CXCL12 chemokine (C-X-C motif) ligand 12 0.00790021
FAM107A family with sequence similarity 107, member A 0.0078855
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00787214
ITM2A integral membrane protein 2A 0.00786765
TPM4 tropomyosin 4 0.00783629
AK1 adenylate kinase 1 0.00780412
ZSCAN18 zinc finger and SCAN domain containing 18 0.00779345
SULF1 sulfatase 1 0.00775988
RGCC regulator of cell cycle 0.00772761
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00771248
SELENOT selenoprotein T 0.00769993
KLF9 Kruppel-like factor 9 0.00768011
FYB1 FYN binding protein 1 0.0076789
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00767055
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00763438
INHBA inhibin, beta A 0.00763195
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00761989
ESRP1 epithelial splicing regulatory protein 1 0.00759513
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00758543
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00757991
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00757537
CETN2 centrin, EF-hand protein, 2 0.00755949
CEL carboxyl ester lipase 0.00755776
RHOH ras homolog family member H 0.00753694
MGP matrix Gla protein 0.00748697
CD14 CD14 molecule 0.00748528
ANOS1 anosmin 1 0.00746896
STK17A serine/threonine kinase 17a 0.00746825
TSPAN6 tetraspanin 6 0.00743108
CKS2 CDC28 protein kinase regulatory subunit 2 0.00739878
TLR4 toll-like receptor 4 0.00739683
SORD sorbitol dehydrogenase 0.00737616
COPS7A COP9 signalosome subunit 7A 0.00736336
C1ORF54 chromosome 1 open reading frame 54 0.00735352
BTF3P11 basic transcription factor 3 pseudogene 11 0.00734481
COL5A2 collagen, type V, alpha 2 0.00731923
CLDN8 claudin 8 0.0072975
ADM adrenomedullin 0.00726461
MME membrane metallo-endopeptidase 0.00726143
ADIRF adipogenesis regulatory factor 0.00723639
GIMAP4 GTPase, IMAP family member 4 0.00722588
KRCC1 lysine-rich coiled-coil 1 0.0071906
ASPN asporin 0.00716684
SELL selectin L 0.00715001
WFDC2 WAP four-disulfide core domain 2 0.00714153
TLR1 toll-like receptor 1 0.00713319
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00713319
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00713229
FAR2 fatty acyl CoA reductase 2 0.0071227
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.00709996
LPXN leupaxin 0.00707105
SLC16A4 solute carrier family 16, member 4 0.00705882
APOO apolipoprotein O 0.00705683
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00704828
PCTP phosphatidylcholine transfer protein 0.00703572
OPHN1 oligophrenin 1 0.0070349
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00701012
CLDND1 claudin domain containing 1 0.00700385
TFRC transferrin receptor 0.00698675
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00698588
SCD5 stearoyl-CoA desaturase 5 0.00698501
MYOF myoferlin 0.00697146
THBS1 thrombospondin 1 0.00696749
MYO1C myosin IC 0.00694369
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00693557
RETREG1 reticulophagy regulator 1 0.00692258
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0069183
LPAR1 lysophosphatidic acid receptor 1 0.00691309
EAPP E2F-associated phosphoprotein 0.00690029
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0068776
TPM2 tropomyosin 2 (beta) 0.00680472
BIRC3 baculoviral IAP repeat containing 3 0.00678074
LHFP lipoma HMGIC fusion partner 0.00677574
IFNGR1 interferon gamma receptor 1 0.00672098
PTBP3 polypyrimidine tract binding protein 3 0.00668608
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00667723
TMEM38B transmembrane protein 38B 0.0066764
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00666894
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00665363
IRS2 insulin receptor substrate 2 0.00664242
SATB2 SATB homeobox 2 0.00663232
MYBPC1 myosin binding protein C, slow type 0.00662572
PDHX pyruvate dehydrogenase complex, component X 0.00660633
EAF2 ELL associated factor 2 0.00659189
TMEM230 transmembrane protein 230 0.0065715
PTPRD protein tyrosine phosphatase, receptor type, D 0.00657129
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00656578
IRF6 interferon regulatory factor 6 0.00656179
CTSK cathepsin K 0.0065254
S100A9 S100 calcium binding protein A9 0.00652432
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.00650216
FGF1 fibroblast growth factor 1 (acidic) 0.00650039
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00649973
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00649359
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00645903
ACOX2 acyl-CoA oxidase 2, branched chain 0.00645398
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00644604
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00644556
CFH complement factor H 0.00644214
SKAP2 src kinase associated phosphoprotein 2 0.006426
GLCE glucuronic acid epimerase 0.00640141
CHMP2B charged multivesicular body protein 2B 0.00639958
PLN phospholamban 0.00637972
LTBP1 latent transforming growth factor beta binding protein 1 0.0063728
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.00635108
GIMAP6 GTPase, IMAP family member 6 0.00634752
RAB25 RAB25, member RAS oncogene family 0.00633648
GSTO1 glutathione S-transferase omega 1 0.00631691
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00631512
DCN decorin 0.00631376
SYT1 synaptotagmin I 0.00628371
NOX4 NADPH oxidase 4 0.00628259
BSPRY B-box and SPRY domain containing 0.00627932
LGALS13 lectin, galactoside-binding, soluble, 13 0.00627296
SPAG1 sperm associated antigen 1 0.00626832
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00625672
FPR1 formyl peptide receptor 1 0.00625432
BCL2A1 BCL2-related protein A1 0.00623578
TEK TEK tyrosine kinase, endothelial 0.0062326
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 0.00623109
CDC42 cell division cycle 42 0.00622643
CFI complement factor I 0.00622096
ALCAM activated leukocyte cell adhesion molecule 0.00622
LY96 lymphocyte antigen 96 0.00620739
HIST1H2AC histone cluster 1, H2ac 0.00619699
PRDX2 peroxiredoxin 2 0.00619296
APIP APAF1 interacting protein 0.00617695
PLIN3 perilipin 3 0.00617082
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0061584
AZIN1 antizyme inhibitor 1 0.00615597
TRIM22 tripartite motif containing 22 0.00614916
GLIPR1 GLI pathogenesis-related 1 0.0061477
CLDN7 claudin 7 0.00614511
EREG epiregulin 0.00614387
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00613917
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00612943
SRGN serglycin 0.0061294
GAS1 growth arrest-specific 1 0.00612132
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00611916
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00609502
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0060853
AMACR alpha-methylacyl-CoA racemase 0.00608372
C1R complement component 1, r subcomponent 0.00608235
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00608233
CD52 CD52 molecule 0.00608037
SLIRP SRA stem-loop interacting RNA binding protein 0.00608023
MPZL2 myelin protein zero-like 2 0.00607431
TOX3 TOX high mobility group box family member 3 0.00607204
MLF1 myeloid leukemia factor 1 0.00606566
ACAT1 acetyl-CoA acetyltransferase 1 0.00603219
CXCR4 chemokine (C-X-C motif) receptor 4 0.00601968
TCTA T-cell leukemia translocation altered 0.00601291
FABP4 fatty acid binding protein 4, adipocyte 0.00600933
CTSS cathepsin S 0.00600474
RHOB ras homolog family member B 0.00600393
ELL2 elongation factor, RNA polymerase II, 2 0.00599996
CYB5A cytochrome b5 type A (microsomal) 0.00597029
LAMA4 laminin, alpha 4 0.00596848

decreased expression

Symbol Name Standardized Value
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0197169
GNAS GNAS complex locus -0.0184464
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0138319
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0138246
PCP4 Purkinje cell protein 4 -0.0120546
GOLGA8A golgin A8 family, member A -0.011982
AMDHD2 amidohydrolase domain containing 2 -0.0117749
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0113643
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.0112076
MAGEA3 melanoma antigen family A3 -0.0110636
FZD2 frizzled class receptor 2 -0.00974927
TUBA4A tubulin, alpha 4a -0.00962338
BCHE butyrylcholinesterase -0.0094537
NSG1 neuron specific gene family member 1 -0.00935017
WT1 Wilms tumor 1 -0.00934354
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00934305
MMP2 matrix metallopeptidase 2 -0.00910237
PEG10 paternally expressed 10 -0.00909241
CADM1 cell adhesion molecule 1 -0.00907016
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00900589
CHIC2 cysteine-rich hydrophobic domain 2 -0.0089883
NXN nucleoredoxin -0.00891551
PRSS21 protease, serine, 21 (testisin) -0.00870789
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -0.00866081
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00865331
TMSB15A thymosin beta 15a -0.00864883
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00855564
QPRT quinolinate phosphoribosyltransferase -0.00851727
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00849893
GSTM3 glutathione S-transferase mu 3 (brain) -0.00844332
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00831758
SLC38A1 solute carrier family 38, member 1 -0.00824853
KRT14 keratin 14, type I -0.00823838
MT1G metallothionein 1G -0.0081895
PLXNA1 plexin A1 -0.00818149
SFTPB surfactant protein B -0.00811346
CYTH1 cytohesin 1 -0.00806218
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00800296
PLD3 phospholipase D family, member 3 -0.00799323
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00788656
MXRA7 matrix-remodelling associated 7 -0.00786052
TSPAN4 tetraspanin 4 -0.00785
L1CAM L1 cell adhesion molecule -0.00778908
APOB apolipoprotein B -0.00765433
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00756468
PILRB paired immunoglobin-like type 2 receptor beta -0.00753916
AMOTL2 angiomotin like 2 -0.00750961
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00750645
TENT4A terminal nucleotidyltransferase 4A -0.00750026
NBPF10 neuroblastoma breakpoint family, member 10 -0.00748407
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00741811
SYCP2 synaptonemal complex protein 2 -0.00741454
AGRN agrin -0.00736749
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00733314
COL9A2 collagen, type IX, alpha 2 -0.00727791
MT1F metallothionein 1F -0.00725766
TGFB1 transforming growth factor, beta 1 -0.00723412
NIT1 nitrilase 1 -0.00720759
MFSD10 major facilitator superfamily domain containing 10 -0.00720737
MAEA macrophage erythroblast attacher -0.00720663
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.00717901
RRBP1 ribosome binding protein 1 -0.00714984
KLK5 kallikrein-related peptidase 5 -0.00713472
DVL1 dishevelled segment polarity protein 1 -0.00713168
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00711673
OSBPL10 oxysterol binding protein-like 10 -0.00710265
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00707813
SST somatostatin -0.00707288
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00705207
ZNF512B zinc finger protein 512B -0.00702576
GUSB glucuronidase, beta -0.00697877
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 -0.00695908
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00693395
APOA1 apolipoprotein A-I -0.00690145
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00688264
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0068796
CCL5 chemokine (C-C motif) ligand 5 -0.0068613
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00684533
SMTN smoothelin -0.00681704
ACADVL acyl-CoA dehydrogenase, very long chain -0.00681371
DHRS1 dehydrogenase/reductase (SDR family) member 1 -0.00678908
SYNGR3 synaptogyrin 3 -0.00675216
PRAME preferentially expressed antigen in melanoma -0.00675108
PCGF3 polycomb group ring finger 3 -0.00671385
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00671
CD70 CD70 molecule -0.00668821
LAMA5 laminin, alpha 5 -0.00668302
ESYT1 extended synaptotagmin-like protein 1 -0.00667625
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00666065
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00665381
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00662727
SIDT2 SID1 transmembrane family, member 2 -0.00660706
DENND4B DENN/MADD domain containing 4B -0.00660162
TTI1 TELO2 interacting protein 1 -0.00659177
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00653694
BANP BTG3 associated nuclear protein -0.00653656
CLCN7 chloride channel, voltage-sensitive 7 -0.00652195
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00651531
PFN2 profilin 2 -0.00651416
FGG fibrinogen gamma chain -0.00650449
COL7A1 collagen, type VII, alpha 1 -0.00649351
STK25 serine/threonine kinase 25 -0.006492
ARMCX6 armadillo repeat containing, X-linked 6 -0.00648859
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -0.00642095
DLK1 delta-like 1 homolog (Drosophila) -0.00641702
FAM193A family with sequence similarity 193, member A -0.00632964
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -0.00632637
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00632529
NPTX1 neuronal pentraxin I -0.00632396
TNIP1 TNFAIP3 interacting protein 1 -0.00631293
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00630312
G6PD glucose-6-phosphate dehydrogenase -0.00629173
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.00629057
FAM110B family with sequence similarity 110, member B -0.0062703
AKAP8 A kinase (PRKA) anchor protein 8 -0.00626757
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00626281
GSE1 Gse1 coiled-coil protein -0.00624368
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00624287
ELAC2 elaC ribonuclease Z 2 -0.00623893
EIF5B eukaryotic translation initiation factor 5B -0.00623419
BRD4 bromodomain containing 4 -0.00623233
NCAM1 neural cell adhesion molecule 1 -0.00623086
SOCS1 suppressor of cytokine signaling 1 -0.00622637
CBS cystathionine-beta-synthase -0.00621673
REC8 REC8 meiotic recombination protein -0.00620354
CCNI cyclin I -0.00619885
RNF167 ring finger protein 167 -0.00619594
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00618778
SRSF11 serine/arginine-rich splicing factor 11 -0.00618694
NEFM neurofilament, medium polypeptide -0.00612946
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00611122
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00610683
CCNL2 cyclin L2 -0.00610403
HIP1R huntingtin interacting protein 1 related -0.00608574
MICALL1 MICAL-like 1 -0.00606547
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00606505
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00605897
AMPD2 adenosine monophosphate deaminase 2 -0.00605142
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.006044
CDR2L cerebellar degeneration-related protein 2-like -0.0060397
MNT MAX network transcriptional repressor -0.00602495
SETDB1 SET domain, bifurcated 1 -0.00601357
SDC3 syndecan 3 -0.00600467
GLS2 glutaminase 2 (liver, mitochondrial) -0.00600236
EHD1 EH-domain containing 1 -0.00596687
ACTC1 actin, alpha, cardiac muscle 1 -0.00596315
PGRMC2 progesterone receptor membrane component 2 -0.00595106
HOMER3 homer scaffolding protein 3 -0.0059432
MEIS1 Meis homeobox 1 -0.00593829
KRT17 keratin 17, type I -0.0059355
MINK1 misshapen-like kinase 1 -0.00592976
PDE3B phosphodiesterase 3B, cGMP-inhibited -0.00592368
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00591878
NFYC nuclear transcription factor Y, gamma -0.00589653
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -0.00589628
FAM160B2 family with sequence similarity 160, member B2 -0.00589233
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -0.00589154
LY6E lymphocyte antigen 6 complex, locus E -0.0058896
DROSHA drosha, ribonuclease type III -0.00587933
MAGEA12 melanoma antigen family A12 -0.00585745
KLK11 kallikrein-related peptidase 11 -0.0058561
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -0.00585515
PENK proenkephalin -0.00585289
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.00585117
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00584497
COCH cochlin -0.00584166
RPN2 ribophorin II -0.00583394
NBEA neurobeachin -0.00582977
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0058263
FSD1 fibronectin type III and SPRY domain containing 1 -0.0058249
ATG2A autophagy related 2A -0.0058124
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00580608
GLS glutaminase -0.0057916
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00578528
DEFA6 defensin, alpha 6, Paneth cell-specific -0.00577168
ATG4B autophagy related 4B, cysteine peptidase -0.00577088
DMXL2 Dmx-like 2 -0.00576914
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.00574366
TWIST1 twist family bHLH transcription factor 1 -0.00574206
OBSL1 obscurin-like 1 -0.00573987
BCKDK branched chain ketoacid dehydrogenase kinase -0.00572311
IL13RA2 interleukin 13 receptor, alpha 2 -0.00572165
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00571697
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00571299
PLXND1 plexin D1 -0.00571044
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -0.00570706
CLUH clustered mitochondria (cluA/CLU1) homolog -0.00568927
BRD9 bromodomain containing 9 -0.00567615
SEPP1 selenoprotein P, plasma, 1 -0.00567454
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.00567209
TACC3 transforming, acidic coiled-coil containing protein 3 -0.0056664
IGSF3 immunoglobulin superfamily, member 3 -0.00565641
MT1H metallothionein 1H -0.0056493
BASP1 brain abundant, membrane attached signal protein 1 -0.00564114
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.0056394
CTSV cathepsin V -0.0056352
MEIS2 Meis homeobox 2 -0.00563263
NMU neuromedin U -0.00562056
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00561189
DGCR8 DGCR8 microprocessor complex subunit -0.00560515
SF3B4 splicing factor 3b, subunit 4, 49kDa -0.00560385
IGHMBP2 immunoglobulin mu binding protein 2 -0.0056029
ATP5F1E ATP synthase F1 subunit epsilon -0.00559383
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00558889
ZNF692 zinc finger protein 692 -0.00558607
SRRM2 serine/arginine repetitive matrix 2 -0.0055856
PDGFC platelet derived growth factor C -0.00558461
FAAP100 FA core complex associated protein 100 -0.00558417
HIC2 hypermethylated in cancer 2 -0.00557757
CDK11A cyclin-dependent kinase 11A -0.00557446
TBL1X transducin (beta)-like 1X-linked -0.00556038
HMGN3 high mobility group nucleosomal binding domain 3 -0.00555924
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00555281
SFTPA2 surfactant protein A2 -0.00553015
DGAT1 diacylglycerol O-acyltransferase 1 -0.00552658
HAUS3 HAUS augmin-like complex, subunit 3 -0.00552032
CLK2 CDC-like kinase 2 -0.00551012
TBCD tubulin folding cofactor D -0.00549514
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.00549234
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00549214
SDC4 syndecan 4 -0.00548926
CENPT centromere protein T -0.00548798
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.00548725
ADGRA3 adhesion G protein-coupled receptor A3 -0.00548679
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00547195
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00546955
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00546123
SFTPC surfactant protein C -0.00546003
CES1 carboxylesterase 1 -0.00545227
RETREG2 reticulophagy regulator family member 2 -0.00544785
DNM1 dynamin 1 -0.00543544
ZBTB17 zinc finger and BTB domain containing 17 -0.00543255
C1ORF115 chromosome 1 open reading frame 115 -0.00542919
PFKP phosphofructokinase, platelet -0.00542812
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00542549
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 -0.0054135
STK26 serine/threonine protein kinase 26 -0.00541102
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.00540588
PFAS phosphoribosylformylglycinamidine synthase -0.00540078
CCNE1 cyclin E1 -0.00539996
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -0.00539395
NOTCH2NL notch 2 N-terminal like -0.00538347
MT1HL1 metallothionein 1H-like 1 -0.00538332
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00537547
AKR1C2 aldo-keto reductase family 1, member C2 -0.00536337
TSPAN9 tetraspanin 9 -0.00536303
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.00535531
PRKCSH protein kinase C substrate 80K-H -0.00535344
TUFT1 tuftelin 1 -0.00534253