MARK4 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description MAP/microtubule affinity-regulating kinase 4|This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 57787)
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100 substrates of the kinase MARK4 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
EP300 E1A binding protein p300
YLPM1 YLP motif containing 1
ARHGAP30 Rho GTPase activating protein 30
OSBPL7 oxysterol binding protein-like 7
LMO7 LIM domain 7
RRAD Ras-related associated with diabetes
ZDHHC8 zinc finger, DHHC-type containing 8
PKP3 plakophilin 3
PGAM4 phosphoglycerate mutase family member 4
NPR1 natriuretic peptide receptor 1
PGAM1 phosphoglycerate mutase 1 (brain)
BSN bassoon presynaptic cytomatrix protein
ATF4 activating transcription factor 4
NFRKB nuclear factor related to kappaB binding protein
SENP7 SUMO1/sentrin specific peptidase 7
SPHK2 sphingosine kinase 2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
CDK17 cyclin-dependent kinase 17
KIF23 kinesin family member 23
PFDN4 prefoldin subunit 4
ISCU iron-sulfur cluster assembly enzyme
TNS3 tensin 3
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
KMT2D lysine (K)-specific methyltransferase 2D
CRTC3 CREB regulated transcription coactivator 3
KIAA1614 KIAA1614
MYO18A myosin XVIIIA
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
FRMD4A FERM domain containing 4A
FCMR Fc fragment of IgM receptor
ZNF609 zinc finger protein 609
USP40 ubiquitin specific peptidase 40
TRIM32 tripartite motif containing 32
SCEL sciellin
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
FYTTD1 forty-two-three domain containing 1
SEPN1 selenoprotein N, 1
SASH1 SAM and SH3 domain containing 1
CRTC2 CREB regulated transcription coactivator 2
AKAP5 A kinase (PRKA) anchor protein 5
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SP140 SP140 nuclear body protein
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
RANBP2 RAN binding protein 2
HDGFRP2 hepatoma-derived growth factor-related protein 2
NAV1 neuron navigator 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
LZTS1 leucine zipper, putative tumor suppressor 1
KIF13B kinesin family member 13B
ZCCHC24 zinc finger, CCHC domain containing 24
TDP1 tyrosyl-DNA phosphodiesterase 1
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ATAD2 ATPase family, AAA domain containing 2
C9ORF172 chromosome 9 open reading frame 172
DVL3 dishevelled segment polarity protein 3
JAKMIP1 janus kinase and microtubule interacting protein 1
SYNE2 spectrin repeat containing, nuclear envelope 2
FLNA filamin A, alpha
HDAC7 histone deacetylase 7
RGS10 regulator of G-protein signaling 10
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
DSP desmoplakin
DENND1A DENN/MADD domain containing 1A
TC2N tandem C2 domains, nuclear
ADCY6 adenylate cyclase 6
EDC4 enhancer of mRNA decapping 4
RGS3 regulator of G-protein signaling 3
NCOA6 nuclear receptor coactivator 6
KLC4 kinesin light chain 4
KIFC3 kinesin family member C3
DOCK7 dedicator of cytokinesis 7
UVSSA UV-stimulated scaffold protein A
MAPT microtubule-associated protein tau
NUP98 nucleoporin 98kDa
CUEDC1 CUE domain containing 1
NOP58 NOP58 ribonucleoprotein
NOP56 NOP56 ribonucleoprotein
EPN2 epsin 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
FOXO3 forkhead box O3
EIF3M eukaryotic translation initiation factor 3, subunit M
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
PPP1R12A protein phosphatase 1, regulatory subunit 12A
SCLT1 sodium channel and clathrin linker 1
R3HCC1 R3H domain and coiled-coil containing 1
DLG5 discs, large homolog 5 (Drosophila)
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SH2D3C SH2 domain containing 3C
ENDOG endonuclease G
TMCC3 transmembrane and coiled-coil domain family 3
NEK6 NIMA-related kinase 6
CCDC88B coiled-coil domain containing 88B
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
SOGA1 suppressor of glucose, autophagy associated 1
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
KIAA1468 KIAA1468
KANK2 KN motif and ankyrin repeat domains 2
AKAP11 A kinase (PRKA) anchor protein 11
SMTN smoothelin